WITHDRAWN: Role of NCAM in Spine Dynamics and Synaptogenesis.

abstract：:Recent evidence reveals that prolactin gene expression (PRL-GE) in mammotropes occurs in pulses, but the molecular process(es) underlying this phenomenon remains unclear. Earlier, we have identified an E-box (E-box133) in the rat PRL promoter that binds several circadian elements and is critical for this dynamic proce...

journal_title：Neurochemical research

authors： Bose S,Ganguly S,Kumar S,Boockfor FR

更新日期：2016-06-01 00:00:00

abstract：:Sex differences exist in the functioning of the two brain corticosteroid receptor systems. Ovarian steroid replacement alters receptor mRNA expression, receptor binding capacities, and receptor affinity. The abundance of both mineralocorticoid receptor (MR) and glucocorticoid receptor (GR) message can be reduced by es...

journal_title：Neurochemical research

authors： Turner BB

更新日期：1997-11-01 00:00:00

abstract：:The wobbler mouse suffers an autosomal recessive mutation producing severe neurodegeneration and astrogliosis in spinal cord. It has been considered a model for amyotrophic lateral sclerosis. We have studied in these animals the expression of two proteins, the growth-associated protein (GAP-43) and the NADPH-diaphoras...

journal_title：Neurochemical research

authors： González Deniselle MC,González SL,Lima AE,Wilkin G,De Nicola AF

更新日期：1999-01-01 00:00:00

abstract：:Chlorpyrifos (CPF), an organophosphorus insecticide is known to cause ill health in non-target animals by inducing oxidative stress. In this study influence of cold stress (15°C and 20°C) and age as modulating factors on CPF induced oxidative stress was addressed to assess age-related differences and vulnerability in ...

journal_title：Neurochemical research

authors： Basha PM,Poojary A

更新日期：2011-02-01 00:00:00

abstract：:Protein kinase A (PKA) plays a crucial role in tau hyperphosphorylation, an early event of Alzheimer disease (AD), and 17beta-estradiol replacement in aging women forestalls the onset of AD. However, the role of estradiol in PKA-induced tau hyperphosphorylation is not known. Here, we investigated the effect of 17beta-...

journal_title：Neurochemical research

authors： Liu XA,Zhu LQ,Zhang Q,Shi HR,Wang SH,Wang Q,Wang JZ

更新日期：2008-09-01 00:00:00

abstract：:Selective blockade of a subset of GABA(A) receptors may be involved in the antipsychotic effects of Clozapine and several other antipsychotic drugs. Seven antipsychotic drugs, and 11 drugs classified as antidepressants that only partially reverse the inhibitory effect of 1 microM GABA on [35S]TBPS binding, do not yiel...

journal_title：Neurochemical research

authors： Squires RF,Saederup E

更新日期：1997-02-01 00:00:00

abstract：:The neurotoxic effects of aluminum are generally associated with reduced antioxidant capacity, increased oxidative stress and apoptosis, which lead to the induction of neurodegenerative processes. Curcumin has a lipophilic polyphenol character and effects of antioxidant and anti-apoptotic. The present study was undert...

journal_title：Neurochemical research

authors： Kar F,Hacioglu C,Uslu S,Kanbak G

更新日期：2019-08-01 00:00:00

abstract：:The elevated plus maze (EPM) is an animal model of anxiety used to test the effects of anxioselective drugs. The loss of the anxiolytic effect of drugs during the second exposure to the EPM is called the "one trial tolerance" (OTT) phenomenon. The present study was designed to investigate the relationship between the ...

journal_title：Neurochemical research

authors： Kocahan S,Akillioglu K

更新日期：2013-07-01 00:00:00

abstract：:The dorsal raphe nucleus (DRN) has been suggested playing an important role in the pathophysiology of post-traumatic stress disorder (PTSD), however the underlying cellular mechanisms are not fully understood. The endoplasmic reticulum (ER) is a critical organelle for synthesis of membrane and secretory proteins, and ...

journal_title：Neurochemical research

authors： Xie J,Han F,Shi Y

更新日期：2014-04-01 00:00:00

abstract：:Histidinemia is an inherited metabolic disorder biochemically characterized by high concentrations of histidine in biological fluids. Usually affected patients are asymptomatic although some individuals have mental retardation and speech disorders. Considering the high prevalence of histidinemia and the scarce informa...

journal_title：Neurochemical research

authors： Rojas DB,Gemelli T,de Andrade RB,Campos AG,Dutra-Filho CS,Wannmacher CM

更新日期：2012-05-01 00:00:00

abstract：:The control and maintenance of the intracellular redox state is an essential task for cells and organisms. NAD(+) and NADH constitute a redox pair crucially involved in cellular metabolism as a cofactor for many dehydrogenases. In addition, NAD(+) is used as a substrate independent of its redox-carrier function by enz...

journal_title：Neurochemical research

authors： Wilhelm F,Hirrlinger J

更新日期：2012-11-01 00:00:00

abstract：:The present work describes the kinetics of enkephalin hydrolysis by plasma enzymes and the fragmentation pattern of both the parent peptide and of the first hydrolysis by-products. The degradation kinetics were followed by positive identification of the hydrolysis fragments by chromatographic methods, by amino acid an...

journal_title：Neurochemical research

authors： Roscetti G,Possenti R,Bassano E,Roda LG

更新日期：1985-10-01 00:00:00

abstract：:In this study, we investigated if subunit displacement and/or alterations in proteasome biosynthesis are responsible for the changes in the levels of constitutive proteasomes (c-20S), immunoproteasomes (i-20S) and the activators PA28 and PA700 in neurons and astrocytes cultured with a cytokine mixture (IFN-γ/TNF-α/IL-...

journal_title：Neurochemical research

authors： Shanley KL,Hu CL,Bizzozero OA

更新日期：2020-04-01 00:00:00

abstract：:We review here the possible mechanisms of neuronal degeneration caused by L-cysteine, an odd excitotoxin. L-Cysteine lacks the omega carboxyl group required for excitotoxic actions via excitatory amino acid receptors, yet it evokes N-methyl-D-aspartate (NMDA) -like excitotoxic neuronal death and potentiates the Ca2+ i...

journal_title：Neurochemical research

authors： Janáky R,Varga V,Hermann A,Saransaari P,Oja SS

更新日期：2000-10-01 00:00:00

abstract：:The diversification of neuronal subtypes during corticogenesis is fundamental to the establishment of the complex cortical structure. Although subtype specification has been assumed to occur in neural progenitor cells, increasing evidence has begun to reveal the plasticity of subtype determination in immature neurons....

journal_title：Neurochemical research

authors： Oishi K,Nakajima K

更新日期：2018-01-01 00:00:00

abstract：:This study was designed to investigate the effects of chronic toluene inhalation in high concentration on lipid peroxidation, antioxidant enzyme activities and ultrastructural changes in the sciatic nerves of rats. Male Wistar albino rats (150-250 g) were divided in two experimental groups: the control and the toluene...

journal_title：Neurochemical research

authors： Coskun O,Oter S,Korkmaz A,Armutcu F,Kanter M

更新日期：2005-01-01 00:00:00

abstract：:Ciliary neurotrophic factor (CNTF) is a promyelinating trophic factor that plays an important role in multiple sclerosis (MS). However, mechanisms by which CNTF expression could be increased in the brain are poorly understood. Recently we have discovered anti-inflammatory and immunomodulatory activities of sodium benz...

journal_title：Neurochemical research

authors： Modi KK,Jana M,Mondal S,Pahan K

更新日期：2015-11-01 00:00:00

abstract：:Disturbance in cholesterol homeostasis appears to be an important factor in the pathogenesis of neurodegenerative disorders. The aim of the present study was to investigate sterol regulatory element binding protein (SREBP) levels in the nuclear extracts of human neuroblastoma cells and the possible interaction of beta...

journal_title：Neurochemical research

authors： Kelicen P,Cincioğlu M,Hizli F,Nordberg A

更新日期：2009-05-01 00:00:00

abstract：:We studied the dose-response characteristics and the temporal profile of inhibition of brain nitric oxide (NO) synthase (NOS) elicited by i.v. administration of the NOS inhibitor nitro-L-arginine methyl ester (L-NAME). L-NAME was administered i.v. in awake rats equipped with a venous cannula. L-NAME was injected in cu...

journal_title：Neurochemical research

authors： Iadecola C,Xu X,Zhang F,Hu J,el-Fakahany EE

更新日期：1994-04-01 00:00:00

abstract：:We estimated catecholamine levels in CSF of 15 epileptics and 75 non-neurological patients utilizing a high performance liquid chromatograph with a highly sensitive fluorometer and found the following results: The dopamine (DA) levels in males were significantly higher than those in females, while norepinephrine (NE) ...

journal_title：Neurochemical research

authors： Hiramatsu M,Fujimoto N,Mori A

更新日期：1982-10-01 00:00:00

abstract：:Rats were long-term morphine-intoxicated by a fluid-diet model ensuring an equal nutrient intake in morphinized and control rats. Uptake of neurotransmitters and D-ala2-met5-enkephalinamide (Enk) was studied in the particulate fractions (obtained at 10,000 g) from well defined brain regions of long-term intoxicated an...

journal_title：Neurochemical research

authors： Rönnbäck L,Hansson E,Cupello A,Rapallino MV,Zeuchner J,Rosengren L

更新日期：1986-02-01 00:00:00

abstract：:We examined the impact of peroxiredoxin-I (Prx-I) and peroxiredoxin-II (Prx-II) stable transduction on oxidative stress in PC12 neurons and NIH3T3 fibroblasts and found variability depending on cell type and Prx subtype. In PC12 neurons, Prx-II suppressed reactive oxygen species (ROS) generation by 36% (p < 0.01) rela...

journal_title：Neurochemical research

authors： Simzar S,Ellyin R,Shau H,Sarafian TA

更新日期：2000-12-01 00:00:00

abstract：:We analyzed two disease model groups with rats infected by Japanese encephalitis virus (JEV), a 90-day group and a 180-day group after JEV infection. The time measured by the modified pole test showed that motor activities in these two groups were slower than those of age-matched control groups. Striatal dopamine (DA)...

journal_title：Neurochemical research

authors： Hamaue N,Ogata A,Terado M,Ohno K,Kikuchi S,Sasaki H,Tashiro K,Hirafuji M,Minami M

更新日期：2006-12-01 00:00:00

abstract：:The real-time iontophoretic method has measured volume fraction and tortuosity of the interstitial component of extracellular space in many regions and under different conditions. To interpret these data computer models of the interstitial space (ISS) of the brain are constructed by representing cells as Basic Cellula...

journal_title：Neurochemical research

authors： Nicholson C,Kamali-Zare P

更新日期：2020-01-01 00:00:00

abstract：:Addiction is a debilitating, chronic psychiatric disorder that is difficult to cure completely owing to the high rate of relapse. Behavioral sensitization is considered to may underlie behavioral changes, such as relapse, caused by chronic abuse of psychomotor stimulants. Thus, its animal models have been widely used ...

journal_title：Neurochemical research

authors： Li L,Liu X,Qiao C,Chen G,Li T

更新日期：2016-10-01 00:00:00

abstract：:Mice with a heterozygous knock-out of the myelin protein P0 gene (P0+/-) develop a neuropathy similar to human Charcot-Marie-Tooth disease. They are indistinguishable from wild-types (WT) at birth and develop a slowly progressing demyelinating neuropathy. The aim of this study was to investigate whether the regenerati...

journal_title：Neurochemical research

authors： Rosberg MR,Alvarez S,Krarup C,Moldovan M

更新日期：2013-06-01 00:00:00

abstract：:(E)-2-(1-hydroxyl-4-oxocyclohexyl) ethyl caffeine (HOEC), a naturally caffeic ester isolated from Incarvillea mairei, has been reported to possess anti-inflammatory activity by targeting 5-lipoxygenase. However, its other potential activities have yet to be explored. In this study, we measured antioxidant activity of ...

journal_title：Neurochemical research

authors： Chen B,Yue R,Yang Y,Zeng H,Chang W,Gao N,Yuan X,Zhang W,Shan L

更新日期：2015-03-01 00:00:00

abstract：:The composition of retrogradely transported axonal proteins was examined by acrylamide gel electrophoresis and gel autoradiography in the experimental neuropathy induced in rats by p-bromophenylacetylurea (BPAU). Protein composition was normal during the early phase of retrograde transport but showed significant abnor...

journal_title：Neurochemical research

authors： Oka N,Brimijoin S

更新日期：1993-06-01 00:00:00

abstract：:The effects of vinpocetine on internal Na+ (Na(i)), cAMP accumulation, internal Ca2+ (Ca(i)) and excitatory amino acid neurotransmitters release, under resting and under depolarized conditions, was investigated in rat striatum synaptosomes. Veratridine (20 microM) or high K+ (30 mM) were used as depolarizing agents. R...

journal_title：Neurochemical research

authors： Sitges M,Nekrassov V

更新日期：1999-12-01 00:00:00

abstract：:The aim of this study is to investigate differences in thyroid-stimulating hormone (TSH) level in patients with acute schizophrenia, unipolar depression, bipolar depression and bipolar mania. Serum level of TSH was measured in 1,685 Caucasian patients (1,064 women, 63.1%; mean age 46.4). Mean serum TSH concentration w...

journal_title：Neurochemical research

authors： Wysokiński A,Kłoszewska I

更新日期：2014-07-01 00:00:00