Abstract:
OBJECTIVE:To determine the plasma levels of substance P (SP) in patients with postoperative stiffness after arthroscopic rotator cuff repair. DESIGN:Plasma samples were obtained at 15 months from surgery from two groups of patients who underwent arthroscopic repair of a rotator cuff tear. In group 1, 30 subjects (14 men, 16 women; mean age 64.6 years, range 47 to 78) with shoulder stiffness 15 months after arthroscopic rotator cuff repair were recruited. In group 2, 30 patients (11 men, 19 women; mean age 57.8 years, range 45 to 77) were evaluated 15 months after successful arthroscopic rotator cuff repair. Immunoassays were performed with commercially available assay kits to measure the plasma levels of SP. RESULTS:Plasma levels of SP in patients with postoperative stiffness were significantly greater than those in the control group (mean 81.06 (SD 27.76) versus 23.49 (5.64), p<0.05). CONCLUSIONS:The plasma concentrations of substance P in patients with shoulder stiffness after arthroscopic rotator cuff repair are higher compared with plasma levels of SP in patients with a good postoperative outcome. The neuronal upregulation of SP shown in the plasma of patients with postoperative shoulder stiffness may underlie not only the symptoms but also its development of adhesive capsulitis.
journal_name
Br J Sports Medjournal_title
British journal of sports medicineauthors
Franceschi F,Longo UG,Ruzzini L,Morini S,Battistoni F,Dicuonzo G,Maffulli N,Denaro Vdoi
10.1136/bjsm.2007.040931subject
Has Abstractpub_date
2008-09-01 00:00:00pages
742-5issue
9eissn
0306-3674issn
1473-0480pii
bjsm.2007.040931journal_volume
42pub_type
杂志文章abstract::Regular physical exercise reduces cardiovascular morbidity and mortality. A small proportion of athletes, however, are at increased risk of exercise-related sudden cardiac death (SCD) as a result of quiescent cardiac anomalies. The preventable nature of such deaths has prompted the medical and sporting governing bodie...
journal_title:British journal of sports medicine
pub_type: 杂志文章,评审
doi:10.1136/bjsm.2008.054874
更新日期:2009-09-01 00:00:00
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journal_title:British journal of sports medicine
pub_type: 杂志文章,随机对照试验
doi:10.1136/bjsm.2009.064840
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abstract:OBJECTIVES:Randomised controlled trials (RCTs) can evaluate how well a particular exercise programme reduces cancer treatment-related side effects. Adequate design and reporting of the exercise prescription employed in RCTs is central to interpreting study findings and translating effective interventions into practice....
journal_title:British journal of sports medicine
pub_type: 杂志文章,评审
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journal_title:British journal of sports medicine
pub_type: 杂志文章
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journal_title:British journal of sports medicine
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doi:10.1136/bjsm.2007.035733
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journal_title:British journal of sports medicine
pub_type: 杂志文章,meta分析,评审
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pub_type: 杂志文章
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journal_title:British journal of sports medicine
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journal_title:British journal of sports medicine
pub_type: 杂志文章,评审
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journal_title:British journal of sports medicine
pub_type: 杂志文章,评审
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更新日期:1997-06-01 00:00:00
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journal_title:British journal of sports medicine
pub_type: 杂志文章,评审
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pub_type: 杂志文章
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journal_title:British journal of sports medicine
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journal_title:British journal of sports medicine
pub_type: 杂志文章
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pub_type: 杂志文章
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