Abstract:
:A consensus microsatellite-based linkage map of the turbot (Scophthalmus maximus) was constructed from two unrelated families. The mapping panel was derived from a gynogenetic family of 96 haploid embryos and a biparental diploid family of 85 full-sib progeny with known linkage phase. A total of 242 microsatellites were mapped in 26 linkage groups, six markers remaining unlinked. The consensus map length was 1343.2 cM, with an average distance between markers of 6.5 +/- 0.5 cM. Similar length of female and male maps was evidenced. However, the mean recombination at common intervals throughout the genome revealed significant differences between sexes, approximately 1.6 times higher in the female than in the male. The comparison of turbot microsatellite flanking sequences against the Tetraodon nigroviridis genome revealed 55 significant matches, with a mean length of 102 bp and high sequence similarity (81-100%). The comparative mapping revealed significant syntenic regions among fish species. This study represents the first linkage map in the turbot, one of the most important flatfish in European aquaculture. This map will be suitable for QTL identification of productive traits in this species and for further evolutionary studies in fish and vertebrate species.
journal_name
Geneticsjournal_title
Geneticsauthors
Bouza C,Hermida M,Pardo BG,Fernández C,Fortes GG,Castro J,Sánchez L,Presa P,Pérez M,Sanjuán A,de Carlos A,Alvarez-Dios JA,Ezcurra S,Cal RM,Piferrer F,Martínez Pdoi
10.1534/genetics.107.075416subject
Has Abstractpub_date
2007-12-01 00:00:00pages
2457-67issue
4eissn
0016-6731issn
1943-2631pii
177/4/2457journal_volume
177pub_type
杂志文章相关文献
GENETICS文献大全abstract::The plant mitochondrial genome is composed of a set of molecules of various sizes that generate each other through recombination between repeated sequences. Molecular observations indicate that these different molecules are present in an equilibrium state. Different compositions of molecules have been observed within ...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1996-09-01 00:00:00
abstract::Neurospora crassa is an established reference organism to investigate carotene biosynthesis and light regulation. However, there is little evidence of its capacity to produce secondary metabolites. Here, we report the role of the fungal-specific regulatory velvet complexes in development and secondary metabolism (SM) ...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.119.302277
更新日期:2019-07-01 00:00:00
abstract::Population structure parameters commonly used for diploid species are reexamined for the particular case of tetrasomic inheritance (autotetraploid species). Recurrence equations that describe the evolution of identity probabilities for neutral genes in an "island model" of population structure are derived assuming tet...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1998-10-01 00:00:00
abstract::The behavior of chromosomal inversions in Escherichia coli depends upon the region they affect. Regions flanking the replication terminus have been termed nondivisible zones (NDZ) because inversions ending in the region were either deleterious or not feasible. This regional phenomenon is further analyzed here. Thirty ...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:2001-04-01 00:00:00
abstract::During animal development, transcription factor activities are modulated by several means, including subcellular localization. The Hox cofactor Extradenticle (Exd) has a dynamic subcellular localization, such that Exd is cytoplasmic by default, but is nuclear when complexed with another homeodomain protein, Homothorax...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.106.066449
更新日期:2007-04-01 00:00:00
abstract::Clf1p is an essential, highly conserved protein in S. cerevisiae that has been implicated in pre-mRNA splicing. Clf1p's ortholog in Drosophila, Crn, is required for normal cell proliferation. Cells depleted of Clf1p arrest primarily with large buds, a single nucleus, a 2C DNA content, and a short, intact mitotic spind...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:2002-04-01 00:00:00
abstract::In Saccharomyces cerevisiae, the Rad52 protein plays a role in both RAD51-dependent and RAD51-independent recombination pathways. We characterized a rad52 mutant, rad52-329, which lacks the C-terminal Rad51-interacting domain, and studied its role in RAD51-independent recombination. The rad52-329 mutant is completely ...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:2003-12-01 00:00:00
abstract::The back-to-back geometry of sister kinetochores is essential in preventing loss or damage of chromosomes during mitosis. Kinetochore orientation is generated in part by a process of resolving kinetochores at the centromere (centromere resolution) prior to spindle interactions. Because few of the genes required for ce...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.107.075275
更新日期:2008-01-01 00:00:00
abstract::In contrast to our growing understanding of patterns of additive genetic variance in single- and multi-trait combinations, the relative contribution of nonadditive genetic variance, particularly dominance variance, to multivariate phenotypes is largely unknown. While mechanisms for the evolution of dominance genetic v...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.115.175489
更新日期:2015-05-01 00:00:00
abstract::We have selected 210 mutants able to grow on sucrose in the presence of 2-deoxyglucose. We identified recessive mutations in three major complementation groups that cause constitutive (glucose-insensitive) secreted invertase synthesis. Two groups comprise alleles of the previously identified HXK2 and REG1 genes, and t...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1987-02-01 00:00:00
abstract::Previous studies on gene expression in aneuploids revealed numerous trans-acting dosage effects. Segmental aneuploidy of each varied chromosomal region exhibited predominantly inverse effects on several target genes. Here, dosage regulation was examined in a maize (Zea mays L.) ploidy series where the complete genomic...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1996-04-01 00:00:00
abstract::We describe 83 recessive autosomal male-sterile mutations, generated by single P element mutagenesis in Drosophila melanogaster. Each mutation has been localized to a lettered subdivision of the polytene map. Reversion analyses, as well as complementation tests using available chromosomal deficiencies, indicate that t...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1993-10-01 00:00:00
abstract::Reproductive isolation that initiates speciation is likely caused by incompatibility among multiple loci in organisms belonging to genetically diverging populations. Laboratory C57BL/6J mice, which predominantly originated from Mus musculus domesticus, and a MSM/Ms strain derived from Japanese wild mice (M. m. molossi...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.106.062976
更新日期:2007-01-01 00:00:00
abstract::Because some metabolic intermediates are involved in more than one pathway, crosstalk between pathways is crucial to maintaining homeostasis. AMP and histidine biosynthesis pathways are coregulated at the transcriptional level in response to adenine availability. 5'-Phosphoribosyl-4-carboxamide-5-aminoimidazole (AICAR...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.104.039396
更新日期:2005-05-01 00:00:00
abstract::The initiation of postembryonic cell divisions by the gonadal precursors of C. elegans requires the activity of gon-2. gon-2 encodes a predicted cation channel (GON-2) of the TRPM subfamily of TRP proteins and is likely to mediate the influx of Ca(2+) and/or Mg(2+). We report here that mutations in gem-4 (gon-2 extrag...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:2003-10-01 00:00:00
abstract::The X and Y chromosomes of Drosophila melanogaster each contain a cluster of several hundred ribosomal RNA genes (rDNA). A nontranscribed spacer region separates adjacent rRNA genes and contains tandem copies of 240 bp repeats that include the initiation site for RNA polymerase I transcription. We show here that Droso...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1990-06-01 00:00:00
abstract::Genomic imprinting is well known as a regulatory property of a few specific chromosomal regions and leads to differential behavior of maternally and paternally inherited alleles. We surveyed the activity of two reporter genes in 23 independent P-element insertions on the heterochromatic Y chromosome of Drosophila mela...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:2002-11-01 00:00:00
abstract::We consider inference for demographic models and parameters based upon postprocessing the output of an MCMC method that generates samples of genealogical trees (from the posterior distribution for a specific prior distribution of the genealogy). This approach has the advantage of taking account of the uncertainty in t...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.107.071910
更新日期:2007-09-01 00:00:00
abstract::RecQ helicases function in the maintenance of genome stability in many organisms. The filamentous fungus Neurospora crassa has two RecQ homologs, QDE3 and RECQ2. We found that the qde-3 recQ2 double mutant showed a severe growth defect. The growth defect was alleviated by mutation in mei-3, the homolog of yeast RAD51,...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.105.041756
更新日期:2006-01-01 00:00:00
abstract::A genetic linkage map was constructed in a backcross family of the red flour beetle, Tribolium castaneum, based largely on sequences from bacterial artificial chromosome (BAC) ends and untranslated regions from random cDNA's. In most cases, dimorphisms were detected using heteroduplex or single-strand conformational p...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.104.032227
更新日期:2005-06-01 00:00:00
abstract::Multilocus surveys of sequence variation can be used to identify targets of directional selection, which are expected to have reduced levels of variation. Following a population bottleneck, the signal of directional selection may be hard to detect because many loci may have low variation by chance and the frequency sp...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.105.054312
更新日期:2006-06-01 00:00:00
abstract::Mutants at the snail locus are zygotically acting embryonic lethals that affect dorsoventral patterning. A comparison of seven mutant alleles shows considerable variation in expressivity and a graded effect along the dorsoventral axis: more extreme alleles result in the abnormal development of the dorsally derived ect...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1984-10-01 00:00:00
abstract::We developed stochastic population genetic theory for mitochondrial and chloroplast genes, using an infinite alleles model appropriate for molecular genetic data. We considered the effects of mutation, random drift, and migration in a finite island model on selectively neutral alleles. Recurrence equations were obtain...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1989-03-01 00:00:00
abstract::In a recent not in this journal (MARUYAMA 1973), one of us has considered, for a certain genetic model, the variance of the distribution of the number of loci having a given gene frequency. The formula given is incorrect. This brief note considers this problem and notes the correct solution in one particular case. ...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1975-05-01 00:00:00
abstract::The neutral rate of allelic substitution is analyzed for a class-structured population subject to a stationary stochastic demographic process. The substitution rate is shown to be generally equal to the effective mutation rate, and under overlapping generations it can be expressed as the effective mutation rate in new...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.114.163345
更新日期:2014-05-01 00:00:00
abstract::Yeast cells subjected to a reversible thermal arrest of meiosis yielded progressively fewer spores per ascus as the arrest was extended. Dissection of two-spored asci by a newly developed method that prevents selection of false asci revealed that the spores were not a random sample of the haploid meiotic products. Mos...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1980-03-01 00:00:00
abstract::We present the results of a restriction site survey of variation at five loci in Drosophila athabasca, complimenting a previous study of the period locus. There is considerably greater differentiation between the three semispecies of D. athabasca at the period locus and two other X-linked genes (no-on-transient-A and ...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1996-10-01 00:00:00
abstract::Sir2 is a highly conserved NAD+-dependent histone deacetylase that functions in heterochromatin formation and promotes replicative life span (RLS) in the budding yeast, Saccharomyces cerevisiae Within the yeast rDNA locus, Sir2 is required for efficient cohesin recruitment and maintaining the stability of the tandem a...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.119.302047
更新日期:2019-05-01 00:00:00
abstract::The additive genomic variance in linear models with random marker effects can be defined as a random variable that is in accordance with classical quantitative genetics theory. Common approaches to estimate the genomic variance in random-effects linear models based on genomic marker data can be regarded as estimating ...
journal_title:Genetics
pub_type: 杂志文章
doi:10.1534/genetics.119.302324
更新日期:2019-10-01 00:00:00
abstract::Various measures have been proposed for characterizing the statistical association that arises between alleles at different loci. Hedrick has compared these measures with the standardized measure D' proposed by Lewontin on the grounds that this latter measure is independent of allele frequency. Although D' has the sam...
journal_title:Genetics
pub_type: 杂志文章
doi:
更新日期:1988-11-01 00:00:00