Abstract:
:Various measures have been proposed for characterizing the statistical association that arises between alleles at different loci. Hedrick has compared these measures with the standardized measure D' proposed by Lewontin on the grounds that this latter measure is independent of allele frequency. Although D' has the same range for all allelic frequencies, in fact, D' is not "independent" of allele frequency, and no measure with that general property is possible for the multilocus association problem. The insolubility of this problem arises from the ill-defined nature of general "association."
journal_name
Geneticsjournal_title
Geneticsauthors
Lewontin RCsubject
Has Abstractpub_date
1988-11-01 00:00:00pages
849-52issue
3eissn
0016-6731issn
1943-2631journal_volume
120pub_type
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