The colinearity of the Sh2/A1 orthologous region in rice, sorghum and maize is interrupted and accompanied by genome expansion in the triticeae.

abstract：:Hybrid sterility is a common form of reproductive isolation between nascent species. Although hybrid sterility is routinely documented and genetically dissected in speciation studies, its developmental basis is rarely examined, especially in generations beyond the F1 generation. To identify phenotypic and genetic dete...

journal_title：Genetics

authors： Schwahn DJ,Wang RJ,White MA,Payseur BA

更新日期：2018-12-01 00:00:00

abstract：:Dis3 encodes a conserved RNase that degrades or processes all RNA species via an N-terminal PilT N terminus (PIN) domain and C-terminal RNB domain that harbor, respectively, endonuclease activity and 3'-5' exonuclease activity. In Schizosaccharomyces pombe, dis3 mutations cause chromosome missegregation and failure in...

journal_title：Genetics

authors： Snee MJ,Wilson WC,Zhu Y,Chen SY,Wilson BA,Kseib C,O'Neal J,Mahajan N,Tomasson MH,Arur S,Skeath JB

更新日期：2016-06-01 00:00:00

abstract：:The biological basis of exercise behavior is increasingly relevant for maintaining healthy lifestyles. Various quantitative genetic studies and selection experiments have conclusively demonstrated substantial heritability for exercise behavior in both humans and laboratory rodents. In the "High Runner" selection exper...

journal_title：Genetics

authors： Hillis DA,Yadgary L,Weinstock GM,Pardo-Manuel de Villena F,Pomp D,Fowler AS,Xu S,Chan F,Garland T Jr

更新日期：2020-11-01 00:00:00

abstract：:In the sensory system of C. elegans, the candidate odorant receptor gene str-2 is strongly expressed in one of the two AWC neurons and weakly in both ASI neurons. Asymmetric AWC expression results from suppression of str-2 expression by a Ca2+/MAPK signaling pathway in one of the AWC neurons early in development. Here...

journal_title：Genetics

authors： Lans H,Jansen G

更新日期：2006-07-01 00:00:00

abstract：:Drosophila melanogaster males deficient for the crystal (cry) locus of the Y chromosome that carry between 15 and 60 copies of the X-linked Stellate (Ste) gene are semisterile, have elevated levels of nondisjunction, produce distorted sperm genotype ratios (meiotic drive), and evince hyperactive transcription of Ste i...

journal_title：Genetics

authors： Belloni M,Tritto P,Bozzetti MP,Palumbo G,Robbins LG

更新日期：2002-08-01 00:00:00

abstract：:The timing of lethality caused by homozygosity for a null allele of the epidermal growth factor receptor (Egfrtm1Mag) in mice is strongly dependent on genetic background. Initial attempts to genetically map background modifiers using Swiss-derived, outbred CD-1 mice were unsuccessful. To investigate the genetic archit...

journal_title：Genetics

authors： Strunk KE,Amann V,Threadgill DW

更新日期：2004-08-01 00:00:00

abstract：:Understanding the initiation of meiosis and the relationship of this event with other key cytogenetic processes are major goals in studying the genetic control of meiosis in higher plants. Our genetic and structural analysis of two mutant alleles of the ameiotic1 gene (am1 and am1-praI) suggest that this locus plays a...

journal_title：Genetics

authors： Golubovskaya I,Grebennikova ZK,Avalkina NA,Sheridan WF

更新日期：1993-12-01 00:00:00

abstract：:RNA editing refers to post-transcriptional processes that alter the base sequence of RNA. Recently, hundreds of new RNA editing targets have been reported. However, the mechanisms that determine the specificity and degree of editing are not well understood. We examined quantitative variation of site-specific editing i...

journal_title：Genetics

authors： Gu T,Gatti DM,Srivastava A,Snyder EM,Raghupathy N,Simecek P,Svenson KL,Dotu I,Chuang JH,Keller MP,Attie AD,Braun RE,Churchill GA

更新日期：2016-02-01 00:00:00

abstract：:Research on the genetics of natural populations was revolutionized in the 1990s by methods for genotyping noninvasively collected samples. However, these methods have remained largely unchanged for the past 20 years and lag far behind the genomics era. To close this gap, here we report an optimized laboratory protocol...

journal_title：Genetics

authors： Snyder-Mackler N,Majoros WH,Yuan ML,Shaver AO,Gordon JB,Kopp GH,Schlebusch SA,Wall JD,Alberts SC,Mukherjee S,Zhou X,Tung J

更新日期：2016-06-01 00:00:00

abstract：:Caenorhabditis elegans' behavioral states, like those of other animals, are shaped by its immediate environment, its past experiences, and by internal factors. We here review the literature on C. elegans behavioral states and their regulation. We discuss dwelling and roaming, local and global search, mate finding, sle...

journal_title：Genetics

authors： Flavell SW,Raizen DM,You YJ

更新日期：2020-10-01 00:00:00

abstract：:The swi8+ gene of Schizosaccharomyces pombe appears to be involved in the termination step of copy synthesis during mating-type (MT) switching. Mutations in swi8 confer a general mutator phenotype and, in particular, generate specific mutations in the MT region. Sequencing of the MT cassettes of the h90 swi8-137 mutan...

journal_title：Genetics

authors： Fleck O,Rudolph C,Albrecht A,Lorentz A,Schär P,Schmidt H

更新日期：1994-11-01 00:00:00

abstract：:The behaviour of two "meiotic drive" systems, Segregation-Distorter (SD) and the sex chromosome sc(4)sc(8) has been examined in the same meiocyte. It has been found that the two systems interact in a specific way. When the distorting effects of SD and sc(4)sc(8) are against each other, there is no detectable interacti...

journal_title：Genetics

authors： Miklos GL,Yanders AF,Peacock WJ

更新日期：1972-09-01 00:00:00

abstract：:Sex differences occur in most species and affect a variety of biological traits including morphology, behavior, and life history. The nematode Caenorhabditis elegans exists as a population of self-fertile hermaphrodites with occasional males, which differ anatomically and behaviorally from hermaphrodites. Here we show...

journal_title：Genetics

authors： van den Berg MC,Woerlee JZ,Ma H,May RC

更新日期：2006-06-01 00:00:00

abstract：:Tetrahymena is a useful eukaryotic model for biochemistry and molecular cell biology studies. We previously demonstrated that targeted ectopic DNA elimination, also called co-Deletion (coDel), can be induced by the introduction of an internal eliminated sequence (IES)-target DNA chimeric construct. In this study, we d...

journal_title：Genetics

authors： Hayashi A,Mochizuki K

更新日期：2015-09-01 00:00:00

abstract：:A plausible explanation for many MHC-linked diseases is lacking. Sequencing of the MHC class I region (coding units or full contigs) in several human and nonhuman primate haplotypes allowed an analysis of single nucleotide variations (SNV) across this entire segment. This diversity was not evenly distributed. It was r...

journal_title：Genetics

authors： Shiina T,Ota M,Shimizu S,Katsuyama Y,Hashimoto N,Takasu M,Anzai T,Kulski JK,Kikkawa E,Naruse T,Kimura N,Yanagiya K,Watanabe A,Hosomichi K,Kohara S,Iwamoto C,Umehara Y,Meyer A,Wanner V,Sano K,Macquin C,Ikeo K,T

更新日期：2006-07-01 00:00:00

abstract：:Rodent inbred line crosses are widely used to map genetic loci associated with complex traits. This approach has proven to be powerful for detecting quantitative trait loci (QTL); however, the resolution of QTL locations, typically approximately 20 cM, means that hundreds of genes are implicated as potential candidate...

journal_title：Genetics

authors： Li R,Lyons MA,Wittenburg H,Paigen B,Churchill GA

更新日期：2005-03-01 00:00:00

abstract：:Eukaryotic chromosome segregation requires a protein complex known as the kinetochore that mediates attachment between mitotic spindle microtubules and centromere-specific nucleosomes composed of the widely conserved histone variant CENP-A. Mutations in kinetochore proteins of the fission yeast Schizosaccharomyces pom...

journal_title：Genetics

authors： Gao C,Langbein L,Kamal F,George AA,Walworth NC

更新日期：2017-10-01 00:00:00

abstract：:A multi-locus model for complete positive assortative mating is discussed. For a two-locus model, if the gene frequencies for the two loci are different, as they are likely to be, it is shown that in equilibrium the population is not composed of only two homozygous types, as is usually thought. The limiting distributi...

journal_title：Genetics

authors： Ghai GL

更新日期：1973-12-01 00:00:00

abstract：:We have studied the deletion of inverted repeats cloned into the EcoRI site within the CAT gene of plasmid pBR325. A cloned inverted repeat constitutes a palindrome that includes both EcoRI sites flanking the insert. In addition, the two EcoRI sites represent direct repeats flanking a region of palindromic symmetry. A...

journal_title：Genetics

authors： Sinden RR,Zheng GX,Brankamp RG,Allen KN

更新日期：1991-12-01 00:00:00

abstract：:Biofilms are microbial communities that form on surfaces. They are the primary form of microbial growth in nature and can have detrimental impacts on human health. Some strains of the budding yeast Saccharomyces cerevisiae form colony biofilms, and there is substantial variation in colony architecture between biofilm-...

journal_title：Genetics

authors： Granek JA,Murray D,Kayrkçi Ö,Magwene PM

更新日期：2013-02-01 00:00:00

abstract：:Filamentous fungi undergo cytokinesis by forming crosswalls termed septa. Here, we describe the genetic and physiological controls governing septation in Aspergillus nidulans. Germinating conidia do not form septa until the completion of their third nuclear division. The first septum is invariantly positioned at the b...

journal_title：Genetics

authors： Harris SD,Morrell JL,Hamer JE

更新日期：1994-02-01 00:00:00

abstract：:The mitochondrial genotype of all F(1) female offspring (426 individuals) of a single Drosophila mauritiana female, heteroplasmic for two types of mtDNA (a short and a long genome), was established. All descendants were heteroplasmic. The earliest eggs laid by this female show the cytoplasmic genetic structure of ovar...

journal_title：Genetics

authors： Solignac M,Génermont J,Monnerot M,Mounolou JC

更新日期：1987-12-01 00:00:00

abstract：:In Drosophila and other insects egg production is related to the nutrients available. Somehow the nutritional status of the environment is translated into hormonal signs that can be "read" by each individual egg chamber, influencing the decision to either develop into an egg or die. We have shown that BR-C is a contro...

journal_title：Genetics

authors： Terashima J,Bownes M

更新日期：2004-08-01 00:00:00

abstract：:The back-to-back geometry of sister kinetochores is essential in preventing loss or damage of chromosomes during mitosis. Kinetochore orientation is generated in part by a process of resolving kinetochores at the centromere (centromere resolution) prior to spindle interactions. Because few of the genes required for ce...

journal_title：Genetics

authors： Stanvitch G,Moore LL

更新日期：2008-01-01 00:00:00

abstract：:A two-locus model is used to analyze the effectiveness of a mixture of insecticides in delaying resistance, compared to the use of the insecticides singly. The effects of factors such as recombination, effective dominance, initial value of allele frequencies and initial value of linkage disequilibrium are considered. ...

journal_title：Genetics

authors： Mani GS

更新日期：1985-04-01 00:00:00

abstract：:Levels of genetic variation and linkage disequilibrium (LD) are critical factors in association mapping methods as well as in identification of loci that have been targets of selection. Maize, an outcrosser, has a high level of sequence variation and a limited extent of LD. Sorghum, a closely related but largely self-...

journal_title：Genetics

authors： Hamblin MT,Mitchell SE,White GM,Gallego J,Kukatla R,Wing RA,Paterson AH,Kresovich S

更新日期：2004-05-01 00:00:00

abstract：:The X chromosome requires special treatment in the mapping of quantitative trait loci (QTL). However, most QTL mapping methods, and most computer programs for QTL mapping, have focused exclusively on autosomal loci. We describe a method for appropriate treatment of the X chromosome for QTL mapping in experimental cros...

journal_title：Genetics

authors： Broman KW,Sen S,Owens SE,Manichaikul A,Southard-Smith EM,Churchill GA

更新日期：2006-12-01 00:00:00

abstract：:Serrate (Ser) is an essential gene in Drosophila melanogaster best known for the Ser dominant (SerD) allele and its effects on wing development. Animals heterozygous or homozygous for SerD are viable and exhibit loss of wing margin tissue and associated bristles and hairs. The Beaded of Goldschmidt (BdG) allele of Ser...

journal_title：Genetics

authors： Hukriede NA,Fleming RJ

更新日期：1997-02-01 00:00:00

abstract：:Resolving the mechanistic and genetic bases of reproductive barriers between species is essential to understanding the evolutionary forces that shape speciation. Intrinsic hybrid incompatibilities are often treated as fixed between species, yet there can be considerable variation in the strength of reproductive isolat...

journal_title：Genetics

authors： Larson EL,Vanderpool D,Sarver BAJ,Callahan C,Keeble S,Provencio LL,Kessler MD,Stewart V,Nordquist E,Dean MD,Good JM

更新日期：2018-07-01 00:00:00

abstract：:The bovine Growth Hormone gene (bGH) is an attractive candidate gene for milk production in cattle. Single-strand conformation polymorphisms at bGH were identified and used to define haplotype configurations at this gene in the Israeli Holstein dairy cattle population (Bos taurus) and in the parent animals of the Inte...

journal_title：Genetics

authors： Lagziel A,Lipkin E,Soller M

更新日期：1996-03-01 00:00:00