FcgammaRIII mediates immunoglobulin G-induced interleukin-10 and is required for chronic Leishmania mexicana lesions.

abstract：:Henle 407 and HeLa cells were compared as hosts for Shigella dysenteriae at a low multiplicity of infection. Efficiency of attachment and invasion without centrifugation, as well as selectivity for pathogenic over nonpathogenic S. dysenteriae without Congo red, were much greater for Henle 407 cells than for HeLa cells...

journal_title：Infection and immunity

authors： Sen A,Leon MA,Palchaudhuri S

更新日期：1990-07-01 00:00:00

abstract：:When phagocytosis of Staphylococcus aureus by human polymorphonuclear leukocytes (PMN) takes place on the surface of cultured human endothelial cells, the endothelial monolayers are damaged by lysosomal enzymes that are released by the PMN. Because PMN can phagocytose opsonized as well as unopsonized staphylococci on ...

journal_title：Infection and immunity

authors： Vandenbroucke-Grauls CM,Thijssen HM,Verhoef J

更新日期：1987-06-01 00:00:00

abstract：:The combining sites of type 1 fimbrial lectins of various species of enterobacteria were studied by measuring the inhibitory activity of linear and branched oligosaccharides and several glycosides of D-mannose on the agglutination of yeast cells by the organisms. The results showed that all five strains of Escherichia...

journal_title：Infection and immunity

authors： Firon N,Ofek I,Sharon N

更新日期：1984-03-01 00:00:00

abstract：:Recombinant adenylate cyclase toxoids are shown to deliver inserted foreign CD4(+)-T-cell epitopes into the major histocompatibility complex class II presentation pathway, inducing a specific CD4(+)-T-cell response in vivo and yielding in vitro stimulation of specific CD4(+) T cells at a 100-times-higher molar efficie...

journal_title：Infection and immunity

authors： Loucká J,Schlecht G,Vodolánová J,Leclerc C,Sebo P

更新日期：2002-02-01 00:00:00

abstract：:Sterile sonic-treated materials of pneumococci grown in media containing N-acetylmannosamine as the carbohydrate source were lethal for mice. Purification of the toxic factor led to its identification as the enzyme neuraminidase. ...

journal_title：Infection and immunity

authors： Kelly R,Greiff D

更新日期：1970-07-01 00:00:00

abstract：:Virulent Treponema pallidum organisms, extracted from infected rabbit testes, were subjected to velocity sedimentation in discontinuous gradients of Hypaque, a high density, low viscosity material. After centrifugation of extracts at 20 C for 45 min at 100,000 x g, treponemes separated into two distinct bands based up...

journal_title：Infection and immunity

authors： Baseman JB,Nichols JC,Rumpp JW,Hayes NS

更新日期：1974-11-01 00:00:00

abstract：:A receptor moiety and blood group substance recognized by the O75X adhesin was studied. Well-defined erythrocytes representing different blood group systems and bacterial derivatives carrying plasmid pBJN406 encoding the adhesin were used in a direct hemagglutination assay. We showed that Dr blood group antigen, a com...

journal_title：Infection and immunity

authors： Nowicki B,Moulds J,Hull R,Hull S

更新日期：1988-05-01 00:00:00

abstract：:In bacterial infections, mononuclear and polymorphonuclear phagocytes are key components of host defenses. Recent investigations have indicated that chemokines are able to recruit and activate phagocytes. In particular, interleukin-8 (IL-8) attracts polymorphonuclear leukocytes (PMNs), while monocyte chemoattractant p...

journal_title：Infection and immunity

authors： Tonetti MS,Imboden MA,Gerber L,Lang NP,Laissue J,Mueller C

更新日期：1994-09-01 00:00:00

abstract：:The purpose of this study was to localize antigenic regions on the flagellin protein of Campylobacter jejuni 81116. This strain has two flagellin genes, flaA and flaB, which are 95% identical; only flaA seems to be expressed in motile C. jejuni 81116 cells. Fragments of flaA and flaB were cloned in the bacterial expre...

journal_title：Infection and immunity

authors： Nuijten PJ,van der Zeijst BA,Newell DG

更新日期：1991-03-01 00:00:00

abstract：:Type II secretion (T2S) is one means by which Gram-negative pathogens secrete proteins into the extracellular milieu and/or host organisms. Based upon recent genome sequencing, it is clear that T2S is largely restricted to the Proteobacteria, occurring in many, but not all, genera in the Alphaproteobacteria, Betaprote...

journal_title：Infection and immunity

authors： Cianciotto NP,White RC

更新日期：2017-04-21 00:00:00

abstract：:The biological response to endotoxin mediated through the Toll-like receptor 4 (TLR4)-MD-2 receptor complex is directly related to lipid A structure or configuration. Endotoxin structure may also influence activation of the MyD88-dependent and -independent signaling pathways of TLR4. To address this possibility, human...

journal_title：Infection and immunity

authors： Zughaier SM,Zimmer SM,Datta A,Carlson RW,Stephens DS

更新日期：2005-05-01 00:00:00

abstract：:Subunits of a proline-rich coccidioidal antigen (Ag2/PRA) of Coccidioides immitis were analyzed by comparison as vaccines in mice. The optimal dose of plasmid vaccine encoding full-length Ag2/PRA was determined to be between 10 and 100 microg. Mice vaccinated with plasmids encoding amino acids (aa) 1 to 106 were as pr...

journal_title：Infection and immunity

authors： Peng T,Shubitz L,Simons J,Perrill R,Orsborn KI,Galgiani JN

更新日期：2002-07-01 00:00:00

abstract：:Monoclonal antibodies to the capsular polysaccharide of Cryptococcus neoformans produce distinct capsular reactions and have biological activities that are determined by serotype specificity. In the present study, polyclonal rabbit anticapsular antibodies were cross-absorbed to produce serotype specificities similar t...

journal_title：Infection and immunity

authors： MacGill TC,MacGill RS,Kozel TR

更新日期：2001-02-01 00:00:00

abstract：:An immunoregulatory mechanism involving release of neutralizing autoantibodies (Aabs) to self cytokines during bacterial infections is presented herein. Intraperitoneal inoculation of Haemophilus influenzae type b into Sprague-Dawley rats resulted in a self-limiting meningitis. High levels of cells expressing mRNA for...

journal_title：Infection and immunity

authors： Bakhiet M,Diab A,Mahamustafa,Jiezhu,Lindqvist L,Link H

更新日期：1997-08-01 00:00:00

abstract：:Trefoil family factor 2 (TFF2), also known as spasmolytic peptide, is a low-molecular-weight protein that is upregulated in gastric tissues infected with Helicobacter or having other inflammatory conditions, but a precise function is yet to be elucidated. The role of TFF2 in the development of gastritis, colitis, and ...

journal_title：Infection and immunity

authors： Kurt-Jones EA,Cao L,Sandor F,Rogers AB,Whary MT,Nambiar PR,Cerny A,Bowen G,Yan J,Takaishi S,Chi AL,Reed G,Houghton J,Fox JG,Wang TC

更新日期：2007-01-01 00:00:00

abstract：:Candida albicans serotype A (C. albicans A) possesses a specific antigen, designated antigen 6, which resides in mannans on the cell surface. To determine the role of the mannan moiety of the C. albicans cell wall in adherence to buccal epithelial cells, we used antigen 6-deficient mutants which had been isolated by s...

journal_title：Infection and immunity

authors： Miyakawa Y,Kuribayashi T,Kagaya K,Suzuki M,Nakase T,Fukazawa Y

更新日期：1992-06-01 00:00:00

abstract：:Extracts of specific granules and azurophil granules from human neutrophils were tested for their bactericidal activity against various lipopolysaccharide mutants of Salmonella typhimurium LT-2. Three purified granule populations, one specific and two azurophil, were obtained by isopycnic centrifugation of homogenized...

journal_title：Infection and immunity

authors： Rest RF,Cooney MH,Spitznagel JK

更新日期：1978-01-01 00:00:00

abstract：:Three-month-old male Crl:CD1(ICR)BR and C3H/HeJ mice were fed chow containing Candida albicans for 14 days, while similar control mice were fed regular food. Stool cultures were done for all mice before and after administration of the special diet. Stool cultures were repeated 48 h, 1 week, and 1 and 3 months after st...

journal_title：Infection and immunity

authors： Samonis G,Anaissie EJ,Rosenbaum B,Bodey GP

更新日期：1990-06-01 00:00:00

abstract：:The predominant gram-positive bacteria in 47 fecal specimens from 10 healthy men were studied by microscopic and cultural counts, by the characterization and tentative identification of isolates, and by the use of fluorescein isothiocyanate (FITC)-conjugated globulins prepared using some of the isolates. Gram-positive...

journal_title：Infection and immunity

authors： Gossling J,Slack JM

更新日期：1974-04-01 00:00:00

abstract：:Invasive aspergillosis is a major threat for patients suffering from chronic granulomatous disease (CGD). Although Aspergillus fumigatus is the most commonly encountered Aspergillus species, the presence of A. nidulans appears to be disproportionately high in CGD patients. The purpose of this study was to investigate ...

journal_title：Infection and immunity

authors： Henriet SS,Hermans PW,Verweij PE,Simonetti E,Holland SM,Sugui JA,Kwon-Chung KJ,Warris A

更新日期：2011-02-01 00:00:00

abstract：:Chronic infections play a significant role in the morbidity and mortality of patients with chronic airflow limitation. By stimulating airway inflammation, persistent infection has the potential to cause airway fibrosis. However, in patient this condition is most typically found in lungs damaged by other factors, such ...

journal_title：Infection and immunity

authors： McIntosh JC,Simecka JW,Ross SE,Davis JK,Miller EJ,Cassell GH

更新日期：1992-07-01 00:00:00

abstract：:Methicillin-resistant Staphylococcus aureus (MRSA) is responsible for large numbers of postsurgical nosocomial infections across the United States and worldwide. Propofol anesthesia is widely used in surgery and in intensive care units, and recent evidence indicates that even brief exposure to propofol can substantial...

journal_title：Infection and immunity

authors： Visvabharathy L,Freitag NE

更新日期：2017-06-20 00:00:00

abstract：:Antibody rises to various virus subcomponents were measured by enzyme-linked immunosorbent assay in the paired sera of volunteers experimentally infected with human coronavirus 229E group viruses. Most of the antibody made during infection was directed against the virus surface projections, with only small amounts of ...

journal_title：Infection and immunity

authors： Macnaughton MR,Hasony HJ,Madge MH,Reed SE

更新日期：1981-03-01 00:00:00

abstract：:Exposure of hamster tracheal rings in organ culture to virulent Mycoplasma pneumoniae organisms leads to alterations in macromolecular biosynthesis and metabolic activity of the respiratory epithelial cells. Avirulent organisms derived from the same parent strain do not produce these effects. During the course of infe...

journal_title：Infection and immunity

authors： Hu PC,Collier AM,Baseman JB

更新日期：1975-04-01 00:00:00

abstract：:The effect of continuous exposure to 80% oxygen on newborn mice with Ureaplasma urealyticum pneumonia was determined. Mice were inoculated intranasally with either U. urealyticum or sterile broth and then housed in either 80% oxygen or room air (21% oxygen). The mice were sacrificed at either 7 or 14 days after inocul...

journal_title：Infection and immunity

authors： Crouse DT,Cassell GH,Waites KB,Foster JM,Cassady G

更新日期：1990-11-01 00:00:00

abstract：:Under certain circumstances, soluble antigens, particulate antigens, and/or microorganisms have been shown to bind to primate erythrocytes via complement receptor 1 (CR1) in the presence of specific antibodies and complement. This immune adherence reaction, specific for CR1, can lead to neutralization of antigens in t...

journal_title：Infection and immunity

authors： Powers JH,Buster BL,Reist CJ,Martin E,Bridges M,Sutherland WM,Taylor RP,Scheld WM

更新日期：1995-04-01 00:00:00

abstract：:Bacterial lipopolysaccharide (LPS) is a potent stimulus of cells, yet a target protein for LPS has not been defined. We used two approaches to define LPS-binding sites on cell surfaces: one assay measured binding of LPS-coated erythrocytes (ELPS) to cultured human cells, and a second measured binding of a radiolabeled...

journal_title：Infection and immunity

authors： Golenbock DT,Hampton RY,Raetz CR,Wright SD

更新日期：1990-12-01 00:00:00

abstract：:The NikR protein is a nickel-dependent regulatory protein which is a member of the ribbon-helix-helix family of transcriptional regulators. The gastric pathogen Helicobacter pylori expresses a NikR ortholog, which was previously shown to mediate regulation of metal metabolism and urease expression, but the mechanism g...

journal_title：Infection and immunity

authors： Ernst FD,Kuipers EJ,Heijens A,Sarwari R,Stoof J,Penn CW,Kusters JG,van Vliet AH

更新日期：2005-11-01 00:00:00

abstract：:Immunologically competent mice and mice with defined immunological deficiencies were infected with Plasmodium yoelii. Splenomegaly, enhanced phagocytosis, and anemia were most marked in infected mice having intact thymic tissue. Whereas the spleens of infected nude mice increased minimally in size, the relative blood ...

journal_title：Infection and immunity

authors： Roberts DW,Weidanz WP

更新日期：1978-06-01 00:00:00

abstract：:Monoclonal antibody MASC1-MR9 of isotype immunoglobulin M was generated in LOU/C rats by immunization with heat-killed Salmonella thompson (serogroup C1, O-antigen 6,7 lipopolysaccharide) bacteria which had been further enriched for O-antigen by coating with homologous lipopolysaccharide. Eight monoclonal antibodies w...

journal_title：Infection and immunity

authors： Nnalue NA,Weintraub A,Lindberg AA

更新日期：1991-01-01 00:00:00