Cord blood stem cell transplantation in primary immune deficiencies.

abstract：PURPOSE OF REVIEW:Children with asthma require care that is seamlessly coordinated so that asthma symptoms are recognized and managed at home and at school. The purpose of this review is to discuss recent consensus recommendations in school-based asthma care. RECENT FINDINGS:The School-based Asthma Management Program ...

journal_title：Current opinion in allergy and clinical immunology

authors： Kakumanu S,Antos N,Szefler SJ,Lemanske RF Jr

更新日期：2017-04-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews recent findings on the skin microbiome. It provides an update on the current understanding of the role of microbiota in healthy skin and in inflammatory and allergic skin diseases. RECENT FINDINGS:Advances in computing and high-throughput sequencing technology have enabled in-dep...

journal_title：Current opinion in allergy and clinical immunology

authors： Zeeuwen PL,Kleerebezem M,Timmerman HM,Schalkwijk J

更新日期：2013-10-01 00:00:00

abstract：PURPOSE OF THE REVIEW:Recent studies on the pathogenesis of allergy in both man and experimental animals continue to show the importance of commensal bacteria in the gastrointestinal tract in stimulating and directing the immune system. The interest in modulating commensal bacterial flora with prebiotics and probiotics...

journal_title：Current opinion in allergy and clinical immunology

authors： Savilahti E,Kuitunen M,Vaarala O

更新日期：2008-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Knowledge of the epidemiology, natural history and risk factors of insect-venom allergy is crucial for improving the clinical management of allergic patients. This review focuses on the recent research on these aspects of Hymenoptera-sting anaphylactic reactions. RECENT FINDINGS:The latest data from ...

journal_title：Current opinion in allergy and clinical immunology

authors： Bilò BM,Bonifazi F

更新日期：2008-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize the current knowledge on remodeling in chronic sinus disease. RECENT FINDINGS:Chronic sinus disease is characterized by persistent inflammation of the nasal and paranasal mucosa and is currently classified into two major subgroups on the basis of the absence (CRSsNP) or presence (CRSwNP)...

journal_title：Current opinion in allergy and clinical immunology

authors： Van Bruaene N,Bachert C

更新日期：2011-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to compare and contrast the newer inhaled corticosteroid (ICS) ciclesonide with older ICSs in terms of pharmacodynamic and pharmacokinetic properties and how these affect comparative efficacy. In addition, clinical dosing strategies for ICSs including as-needed use will b...

journal_title：Current opinion in allergy and clinical immunology

authors： Stoloff SW,Kelly HW

更新日期：2011-08-01 00:00:00

abstract：PURPOSE:The aim of this review is to highlight the prevalence of allergic rhinitis in athletes and the impact this condition may have on their athletic performance. Furthermore, the optimal management of medical conditions in the elite athlete forms an important part of protecting the health of the athlete. RECENT FIN...

journal_title：Current opinion in allergy and clinical immunology

authors： Dijkstra HP,Robson-Ansley P

更新日期：2011-04-01 00:00:00

abstract：PURPOSE OF REVIEW:One strategy to improve asthma control is to identify risk factors for uncontrolled asthma in epidemiologic studies and then consider those risk factors as potential targets for intervention. This article reviews predictors of impairment based on validated tools and predictors of severe asthma exacerb...

journal_title：Current opinion in allergy and clinical immunology

authors： Schatz M

更新日期：2012-06-01 00:00:00

abstract：:Conventional immunotherapy may be associated with the development of adverse reactions, including anaphylaxis, due to the use of increasing doses of allergen. Standardization of extracts is necessary in order to assess the correct amount of allergen administered. In recent years, increased knowledge on the molecular s...

journal_title：Current opinion in allergy and clinical immunology

authors： Pomés A,Chapman MD

更新日期：2001-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to describe the impact of asthma treatment non-adherence on patients and the healthcare system, and to outline areas of responsibility towards improved adherence. RECENT FINDINGS:The average cost of healthcare expenses for each person in the United States in 2002 was 544...

journal_title：Current opinion in allergy and clinical immunology

authors： Bender BG,Rand C

更新日期：2004-06-01 00:00:00

abstract：PURPOSE OF REVIEW:In the concept of food allergy prevention, no successful strategy could be identified until now. Although interventional trials using probiotics, prebiotics, hydrolyzed formula and bacterial lysates early in infancy were found to reduce the incidence of atopic dermatitis, no effect on food sensitizati...

journal_title：Current opinion in allergy and clinical immunology

authors： Lau S

更新日期：2013-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Vitamin D deficiency has been rediscovered as a public-health problem worldwide. It has been postulated that vitamin D deficiency may explain a portion of the asthma epidemic. The purpose of this review is to present the evidence for a role of vitamin D in asthma. RECENT FINDINGS:Both animal models a...

journal_title：Current opinion in allergy and clinical immunology

authors： Litonjua AA

更新日期：2009-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an update on the syndrome X-linked hypogammaglobulinemia with isolated growth hormone deficiency, focusing on the pedigree described originally. RECENT FINDINGS:An additional case of X-linked hypogammaglobulinemia with isolated growth hormone deficiency and an unaffected male have been bor...

journal_title：Current opinion in allergy and clinical immunology

authors： Stewart DM,Tian L,Notarangelo LD,Nelson DL

更新日期：2005-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome is a fatal syndrome of overwhelming autoimmunity. Recent identification of FOXP3 as the causative gene and realization that this same gene defect occurs in the mutant mouse Scurfy has yielded new insights and hopes of unraveling ...

journal_title：Current opinion in allergy and clinical immunology

authors： Torgerson TR,Ochs HD

更新日期：2002-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Despite asthma being widely regarded as a heterogeneous disease, a consensus for an accurate system of classification has not been agreed. Recent studies have suggested that the recognition of subphenotypes of asthma based on the pattern of airway inflammation may be particularly useful in increasing ...

journal_title：Current opinion in allergy and clinical immunology

authors： Green RH,Brightling CE,Bradding P

更新日期：2007-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The current EAACI/GA²LEN/EDF/WAO treatment guidelines for the management of urticaria recommend omalizumab as fourth-line therapy. Within the last year, many reports of omalizumab treatment in chronic urticaria have been published. RECENT FINDINGS:Two multicenter, randomized, placebo-controlled trial...

journal_title：Current opinion in allergy and clinical immunology

authors： Metz M,Maurer M

更新日期：2012-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Mastocytosis is a rare disease characterized by increased mast cells in skin and/or internal organs. We evaluate the impact of mastocytosis on diagnosis and treatment of Hymenoptera venom allergy. RECENT FINDINGS:Patients with Hymenoptera venom allergy who suffer from mastocytosis develop life-threat...

journal_title：Current opinion in allergy and clinical immunology

authors： Ruëff F,Placzek M,Przybilla B

更新日期：2006-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of the present review is to describe recent approaches aimed at improving the treatment of allergic diseases through allergen-specific immunotherapy (SIT). Special emphasis will be given to the approach based on specific targeting of the major histocompatibility complex (MHC) class-II anti...

journal_title：Current opinion in allergy and clinical immunology

authors： Crameri R,Kündig TM,Akdis CA

更新日期：2009-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide a fast overview about the introduction and development of anticholinergic drugs in Western medicine to their current indications particularly in asthma. RECENT FINDINGS:Although short-acting muscarinic antagonists have been positioned in the last 15 years for the treatment of adults and ch...

journal_title：Current opinion in allergy and clinical immunology

authors： Rodrigo GJ

更新日期：2018-02-01 00:00:00

abstract：:A number of recent cohort and cross-sectional studies have contributed substantial knowledge to factors that influence the early development of asthma. Here, we summarize the recent evidence for the role of early life events such as prenatal factors, infections, diet and allergen exposure, and discuss the implications...

journal_title：Current opinion in allergy and clinical immunology

authors： Peat JK,Mellis CM

更新日期：2002-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Due to the continuously changing environmental conditions, it is necessary to regularly monitor and update the spectrum of contact allergens that elicit contact dermatitis. New contact allergens and known contact allergens with currently increasing importance need to be identified for diagnostic and p...

journal_title：Current opinion in allergy and clinical immunology

authors： Brasch J

更新日期：2007-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Asthma and rhinitis are commonly associated and they influence their respective control. New observations have contributed to better understand how to assess those conditions and how they influence each other. RECENT FINDINGS:Recent studies found that not only the intensity, but also the duration of ...

journal_title：Current opinion in allergy and clinical immunology

authors： Boulay ME,Morin A,Laprise C,Boulet LP

更新日期：2012-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Allergic diseases have only recently gained serious attention in Africa. This review discusses recent studies that have focused on allergy among Africans and people of African ancestry. RECENT FINDINGS:Time trend studies of the prevalence of allergies in Africa show a consistent increase over a perio...

journal_title：Current opinion in allergy and clinical immunology

authors： Obeng BB,Hartgers F,Boakye D,Yazdanbakhsh M

更新日期：2008-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To provide an overview on the role of gut mucosal immunity in the development of tolerance against allergy to food. RECENT FINDINGS:The gastrointestinal tract, through innate and specific immunologic factors, acts as a defense against ingested antigens. In addition to the mucous membrane integrity an...

journal_title：Current opinion in allergy and clinical immunology

authors： Chahine BG,Bahna SL

更新日期：2010-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To review the results from recent studies that assessed the burden of allergic diseases on the patients' every-day life, or contributed to new advances in monitoring quality-of-life in allergic disorders. This review will not report the numerous clinical trials that included quality-of-life as an outc...

journal_title：Current opinion in allergy and clinical immunology

authors： Leynaert B,Soussan D

更新日期：2003-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of the present review is to describe new antilymphangiogenic treatment strategies and recent findings on strain-dependency of corneal lymphangiogenesis and the interdependency between blood and lymphatic vessel growth. RECENT FINDINGS:Studies on mice have revealed that apart from haemangi...

journal_title：Current opinion in allergy and clinical immunology

authors： Regenfuss B,Bock F,Cursiefen C

更新日期：2012-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To familiarize the reader with the recent developments in the identification of food protein allergens by proteomics mass spectrometry-based methods, named allergenomics. RECENT FINDINGS:The proteomic analysis of food protein allergens has became a hot topic in the food safety field in recent years. ...

journal_title：Current opinion in allergy and clinical immunology

authors： Di Girolamo F,Muraca M,Mazzina O,Lante I,Dahdah L

更新日期：2015-06-01 00:00:00

abstract：PURPOSE OF REVIEW:The phenomenon of intrinsic or nonatopic asthma continues to raise questions about the possible role of IgE-mediated mechanisms in asthma pathogenesis. With the current availability of anti-IgE therapy for asthma, clarification of this issue has never been more timely and relevant. RECENT FINDINGS:Th...

journal_title：Current opinion in allergy and clinical immunology

authors： Corrigan C

更新日期：2004-02-01 00:00:00

abstract：PURPOSE OF REVIEW:The purpose of this review is to summarize the recent evidence on the effect of cleaning jobs on asthma, based on case reports and series of occupational asthma among cleaners, and epidemiological studies on the relationship between different characteristics of cleaning and asthma risk, as well as to ...

journal_title：Current opinion in allergy and clinical immunology

authors： Jaakkola JJ,Jaakkola MS

更新日期：2006-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Personalized medicine encompasses the use of biological information such as genomics to provide tailored interventions for patients. The review explores the ethical, legal, and social issues that have emerged with personalized medicine and must be considered because of the complex nature of providing ...

journal_title：Current opinion in allergy and clinical immunology

authors： Joly Y,Saulnier KM,Osien G,Knoppers BM

更新日期：2014-10-01 00:00:00