Outcomes of transplantation in children with primary hepatic malignancy.

Abstract:

:HBL and HCC are the most common hepatic malignancies in children. The role of OLT in children with HCC is still a matter of debate. The aim of this study was to review our experience of OLT for HCC. Medical records of patients (<18 yr) who underwent OLT for HCC were reviewed and compared to children who underwent OLT for HBL and for indications other than malignancy. There were 25 patients: HCC (10 cases) and HBL (15 cases). The actuarial patient survival for HCC at one and five yr was 100% and 83.3%, for the HBL group the survival was 86.7% at both one and five yr, and for indications (n=377) other than malignancy the patient survival for pediatric OLT at our center was 87.7% and 84.7% at one and five yr, respectively. The actuarial recurrence free survival at five yr was 83.3% for HCC and 66.8% for HBL. In conclusion, OLT is a good therapeutic modality for children with HCC and HBL.

journal_name

Pediatr Transplant

authors

Beaunoyer M,Vanatta JM,Ogihara M,Strichartz D,Dahl G,Berquist WE,Castillo RO,Cox KL,Esquivel CO

doi

10.1111/j.1399-3046.2007.00751.x

subject

Has Abstract

pub_date

2007-09-01 00:00:00

pages

655-60

issue

6

eissn

1397-3142

issn

1399-3046

pii

PTR751

journal_volume

11

pub_type

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