The management of dyslipidaemias in antiretroviral-treated HIV infection: a systematic review.

abstract：OBJECTIVES:To study the impact of highly active antiretroviral therapy (HAART) on isotype switching and avidity maturation of HIV-1-specific immunoglobulin G (IgG) in patients with primary HIV-1 infection (PHI). METHODS:We studied the emergence and the evolution of anti-HIV IgG antibodies by quantitative immunoblottin...

journal_title：HIV medicine

authors： Adalid-Peralta L,Grangeot-Keros L,Rudent A,Ngo-Giang-Huong N,Krzysiek R,Goujard C,Deveau C,Le Gall M,Meyer L,Emilie D,Rouzioux C

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVES:Antiretroviral therapy (ART) in HIV-infected patients is associated with increased cardiovascular risk. Circulating markers of endothelial dysfunction may be used to study early atherogenesis. The aim of our study was to investigate changes in such markers during initiation of ART. METHODS:In 115 HIV-positi...

journal_title：HIV medicine

authors： Kristoffersen US,Kofoed K,Kronborg G,Giger AK,Kjaer A,Lebech AM

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVES:Efforts are needed to improve informed consent of participants in research. The Strategic Timing of AntiRetroviral Therapy (START) study provides a unique opportunity to study the effect of length and complexity of informed consent documents on understanding and satisfaction among geographically diverse part...

journal_title：HIV medicine

authors： Denning E,Sharma S,Smolskis M,Touloumi G,Walker S,Babiker A,Clewett M,Emanuel E,Florence E,Papadopoulos A,Sánchez A,Tavel J,Grady C,International Network for Strategic Initiatives in Global HIV Trials (INSIGHT) START Study Grou

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVES:In adults with horizontally acquired HIV infection, an inverted CD4:CD8 ratio is associated with persistent immune activation, size of HIV reservoir and predicts an increased risk of non-AIDS-defining adverse events. Normalization of this ratio with antiretroviral therapy (ART) is suboptimal in adults, despi...

journal_title：HIV medicine

authors： Seers T,Vassallo P,Pollock K,Thornhill JP,Fidler S,Foster C

更新日期：2018-10-01 00:00:00

abstract：OBJECTIVE:To measure the evolution of proviral HIV-1 DNA levels in patients receiving highly active antiretroviral therapy (HAART) compared to those treated with HAART plus interleukin-2 (IL-2) and hydroxyurea. DESIGN:Prospective randomised trial. METHODS:Twenty-two HIV-1 infected patients were randomly assigned to a...

journal_title：HIV medicine

authors： Lafeuillade A,Poggi C,Chadapaud S,Hittinger G,Khiri H,Halfon P

更新日期：2001-07-01 00:00:00

abstract：OBJECTIVES:Dyslipidaemia has become a common problem in HIV disease, especially in patients on current antiretroviral therapy. However, the pathogenic mechanisms involved are not well understood or documented using conventional lipid measurements. METHODS:Using a cross-sectional design, the prevalence of abnormal stan...

journal_title：HIV medicine

authors： Rimland D,Guest JL,Hernández I,Del Rio C,Le NA,Brown WV

更新日期：2005-09-01 00:00:00

abstract：OBJECTIVES:A significant percentage of patients infected with HIV-1 experience only suboptimal CD4 cell recovery while treated with combination therapy (cART). It is still unclear whether viral properties such as cell tropism play a major role in this incomplete immune response. This study therefore intended to follow ...

journal_title：HIV medicine

authors： Bader J,Schöni-Affolter F,Böni J,Gorgievski-Hrisoho M,Martinetti G,Battegay M,Klimkait T,Swiss HIV Cohort Study.

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVES:This paper examines changes in barriers to HIV testing amongst gay men. We compared data collected in 2000 and 2010 to assess changes in HIV testing behaviours, in community-level perceptions of barriers to HIV testing, and in the relative contributions of barrier measures. METHODS:Cross-sectional surveys w...

journal_title：HIV medicine

authors： Flowers P,Knussen C,Li J,McDaid L

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVE:Data from observational cohorts may be influenced by population structure and loss to follow-up (LTFU). Quality of care may be associated with participation in cohort networks. We aimed to study the participation, characteristics and retention rates of immigrants in the Swiss HIV Cohort Study (SHCS). METHODS...

journal_title：HIV medicine

authors： Thierfelder C,Weber R,Elzi L,Furrer H,Cavassini M,Calmy A,Bernasconi E,Gutmann C,Ledergerber B,Swiss HIV Cohort Study Group.

更新日期：2012-02-01 00:00:00

abstract：OBJECTIVES:Different experimental approaches have shown that, despite plasma viral loads under the threshold of detection, HIV-1 frequently continues to replicate in patients receiving potent antiretroviral therapy. However, whether this low-grade viral replication is sufficient for the generation of new major quasispe...

journal_title：HIV medicine

authors： Birk M,Aleman S,Visco-Comandini U,Sönnerborg A

更新日期：2000-10-01 00:00:00

abstract：OBJECTIVES:The perceived threat of HIV transmission through spitting and biting is evidenced by the increasing use of "spit hoods" by Police Forces in the UK. In addition, a draft parliamentary bill has called for increased penalties for assaults on emergency workers, citing the risk of communicable disease transmissio...

journal_title：HIV medicine

authors： Cresswell FV,Ellis J,Hartley J,Sabin CA,Orkin C,Churchill DR

更新日期：2018-04-23 00:00:00

abstract：OBJECTIVES:Adipose tissue affects several aspects of the cellular immune system, but prior epidemiological studies have differed on whether a higher body mass index (BMI) promotes CD4 T-cell recovery on antiretroviral therapy (ART). The objective of this analysis was to assess the relationship between BMI at ART initia...

journal_title：HIV medicine

authors： Koethe JR,Jenkins CA,Lau B,Shepherd BE,Silverberg MJ,Brown TT,Blashill AJ,Anema A,Willig A,Stinnette S,Napravnik S,Gill J,Crane HM,Sterling TR,North American AIDS Cohort Collaboration on Research and Design (NA-ACCORD).

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to compare the metabolic and morphological effects of enfuvirtide plus an optimized background (OB) regimen vs. OB alone (control group) in treatment-experienced patients in the T-20 vs. Optimized Regimen Only (TORO) studies. METHODS:Body composition and metabolic changes were invest...

journal_title：HIV medicine

authors： Cooper DA,Cordery DV,Reiss P,Henry K,Nelson M,O'Hearn M,Reynes J,Arastéh K,Chung J,Rowell L,Guimaraes D,Bertasso A,TORO 1 and TORO 2 Study Groups.

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:Mucocutaneous manifestations such as oral candidiasis (OC) and seborrheic dermatitis (SD) are very common HIV-related opportunistic events and are usually initial markers of immunodeficiency. AIM:The purpose of this study was to evaluate the efficacy of highly active antiretroviral therapy (HAART) in the re...

journal_title：HIV medicine

authors： Dunic I,Vesic S,Jevtovic DJ

更新日期：2004-01-01 00:00:00

abstract：OBJECTIVES:With the prolonged survival time of AIDS patients, complications of various systems and organs of HIV infection are increasingly prominent. These diseases have become the major factors influencing the quality of life and prognosis of HIV-infected persons, and multidisciplinary cooperation treatment is urgent...

journal_title：HIV medicine

authors： Lin L,Li TS

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:To study the impact of effective highly active antiretroviral therapy (HAART) on the preservation of long-term CD4 memory cells induced by vaccines in HIV-1-infected patients. METHODS:Thirty HIV-1-positive patients on HAART with undetectable viral load were randomized into three groups: 10 received HIV-1 rgp...

journal_title：HIV medicine

authors： Hejdeman B,Leandersson AC,Fredriksson EL,Sandström E,Wahren B,Bratt G

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to investigate HIV testing practice among female sex workers (FSWs) and men who have sex with men (MSM) in Tbilisi, Georgia and to identify determinants of never testing behaviour among MSM. METHODS:Data obtained in two rounds of bio-behavioural surveys among FSWs (2006 and 2009) an...

journal_title：HIV medicine

authors： Tsereteli N,Chikovani I,Chkhaidze N,Goguadze K,Shengelia N,Rukhadze N

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVES:The incidence of sexually transmitted infections (STIs) and HIV infection remains high in gay, bisexual, and other men who have sex with men (MSM) in the UK, and sexualized drug use ("chemsex") and injecting drug use ("slamsex") may play a part in this. We aimed to characterize HIV-positive MSM engaging in c...

journal_title：HIV medicine

authors： Pufall EL,Kall M,Shahmanesh M,Nardone A,Gilson R,Delpech V,Ward H,Positive Voices study group.

更新日期：2018-04-01 00:00:00

abstract：OBJECTIVES:Pregnant women experience physiological changes during pregnancy that can have a significant impact on antiretroviral pharmacokinetics. Ensuring optimal plasma concentrations of antiretrovirals is essential for maternal health and to minimize the risk of vertical transmission. Here we describe atazanavir/rit...

journal_title：HIV medicine

authors： Else LJ,Jackson V,Brennan M,Back DJ,Khoo SH,Coulter-Smith S,Lambert JS

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVES:To determine whether HIV-infected mothers knew the HIV status of their children, enabling the offer of targeted testing of children at risk. METHODS:All HIV-positive women attending the genitourinary medicine clinic at a district general hospital in the United Kingdom were asked whether they had children an...

journal_title：HIV medicine

authors： Eisenhut M,Sharma V,Kawsar M,Balachandran T

更新日期：2008-04-01 00:00:00

abstract：:A 25-year-old HIV-infected African albino woman developed an aggressive Merkel cell carcinoma on her face and at least 10 basal cell carcinomas, mainly on sun-exposed parts of her body. HIV infection, immune deficiency and sun exposure are known risk factors for the development of Merkel cell carcinoma. Chemotherapy a...

journal_title：HIV medicine

authors： Colebunders R,Bottieau E,Van den Brande J,Colpaert C,Van Marck E

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVES:The World Health Organization (WHO) recommends screening HIV-infected people for cryptococcal antigens to identify cryptococcosis, a major cause of AIDS-related deaths. As the burden of cryptococcosis is unknown in South Africa's KwaZulu-Natal province, we assessed the cryptococcal antigenuria prevalence amo...

journal_title：HIV medicine

authors： Drain PK,Kleene JM,Coleman SM,Losina E,Katz JN,Giddy J,Ross D,Freedberg KA,Bassett IV

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Metabolic diseases are frequently observed in HIV-infected persons and, as the risk of contracting these diseases is age-related, their prevalence will increase in the future as a consequence of the benefits of antiretroviral therapy (ART). SUMMARY OF GUIDELINES:All HIV-infected persons should be screened a...

journal_title：HIV medicine

authors： Lundgren JD,Battegay M,Behrens G,De Wit S,Guaraldi G,Katlama C,Martinez E,Nair D,Powderly WG,Reiss P,Sutinen J,Vigano A,EACS Executive Committee.

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVES:The aims of the present study were to estimate the prevalence of renal impairment (RI) among HIV-infected adult patients and to investigate the associated factors. METHODS:A cross-sectional survey was conducted in a French hospital-based cohort. Clearance of creatinine (CC) was calculated using the Cockcrof...

journal_title：HIV medicine

authors： Déti EK,Thiébaut R,Bonnet F,Lawson-Ayayi S,Dupon M,Neau D,Pellegrin JL,Malvy D,Tchamgoué S,Dabis F,Morlat P,Groupe d'Epidémiologie Clinique du SIDA en Aquitaine.

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:The world-wide AIDS epidemic is reflected in Western Europe in an increasing number of HIV-infected persons who originate from Africa. We describe the characteristics and response to antiretroviral therapy (ART) of HIV-infected patients born in Africa and living in France. METHODS:Analysis of data from the ...

journal_title：HIV medicine

authors： Breton G,Lewden C,Spire B,Salmon D,Brun-Vézinet F,Duong M,Allavena C,Leport C,Salamon R,APROCO COPILOTE ANRS CO8 Study Group.

更新日期：2007-04-01 00:00:00

abstract：OBJECTIVES:We examined whether insulin-resistant lipodystrophic HIV-infected patients with known high fasting prehepatic insulin secretion rates (FISRs) displayed alterations in first-phase prehepatic insulin response to intravenous glucose (ISREG0-10 min). METHODS:Eighteen normoglycaemic lipodystrophic HIV-infected (...

journal_title：HIV medicine

authors： Haugaard SB,Andersen O,Pedersen SB,Dela F,Deacon CF,Holst JJ,Iversen J,Madsbad S

更新日期：2006-04-01 00:00:00

abstract：OBJECTIVES:Mortality in young people with perinatally acquired HIV infection (PHIV) following transfer to adult care has not been characterized in the UK. We conducted a multicentre audit to establish the number of deaths and associated factors. METHODS:Fourteen adult clinics caring for infected young people reported ...

journal_title：HIV medicine

authors： Fish R,Judd A,Jungmann E,O'Leary C,Foster C,HIV Young Persons Network (HYPNet).

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVES:Socio-economic factors and lifestyle are known to differ across geographies and populations, which may result in distinct risk profiles for cardiovascular disease (CVD). This study assessed carotid intima-media thickness (CIMT), a proxy for CVD, and its determinants in two groups of people living with HIV (P...

journal_title：HIV medicine

authors： Roozen G,Vos AG,Tempelman HA,Venter W,Grobbee DE,Scheuermaier K,Klipstein-Grobusch K

更新日期：2020-07-01 00:00:00

abstract：:We describe the characteristics of HIV post-exposure prophylaxis (PEP) recipients and PEP indications at 56 Dean Street, a central London sexual health clinic. PEP was prescribed on 577 occasions. Most (97%) was given for unprotected anal intercourse. Over a fifth of exposures involved recreational drug use. Of the pa...

journal_title：HIV medicine

authors： Whitlock G,Nwokolo N,McOwan A

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVE:To assess adherence to the British HIV Association (BHIVA) 2001 guidelines for the management of HIV-infected pregnant women. METHODS:A survey and a case note review were carried out using structured questionnaires sent to providers of adult HIV care in the UK and Ireland. Participants were women with HIV in...

journal_title：HIV medicine

authors： McDonald C,Curtis H,de Ruiter A,Johnson MA,Welch J,British HIV Association (BHIVA) and the BHIVA audit subcommittee.

更新日期：2006-07-01 00:00:00