Prevalence and factors associated with renal impairment in HIV-infected patients, ANRS C03 Aquitaine Cohort, France.

abstract：OBJECTIVES:Antiretroviral therapy during pregnancy is recommended to reduce the risk of mother-to-child transmission of HIV and for maternal care management. Physiological changes during pregnancy can affect pharmacokinetics, potentially altering pharmacological activity. We therefore evaluated the pharmacokinetics of ...

journal_title：HIV medicine

authors： Zorrilla CD,Wright R,Osiyemi OO,Yasin S,Baugh B,Brown K,Coate B,Verboven P,Mrus J,Falcon R,Kakuda TN

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVES:Antiretroviral therapy (ART) in HIV-infected patients is associated with increased cardiovascular risk. Circulating markers of endothelial dysfunction may be used to study early atherogenesis. The aim of our study was to investigate changes in such markers during initiation of ART. METHODS:In 115 HIV-positi...

journal_title：HIV medicine

authors： Kristoffersen US,Kofoed K,Kronborg G,Giger AK,Kjaer A,Lebech AM

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVES:Across Europe, almost a third of individuals infected with HIV do not enter health care until late in the course of their infection. Surveillance to identify the extent to which late presentation occurs remains inadequate across Europe and is further complicated by the lack of a common clinical definition of...

journal_title：HIV medicine

authors： Antinori A,Coenen T,Costagiola D,Dedes N,Ellefson M,Gatell J,Girardi E,Johnson M,Kirk O,Lundgren J,Mocroft A,D'Arminio Monforte A,Phillips A,Raben D,Rockstroh JK,Sabin C,Sönnerborg A,De Wolf F,European Late Presenter

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVES:An article by the Swiss AIDS Commission states that patients with stably suppressed viraemia [i.e. several successive HIV-1 RNA plasma concentrations (viral loads, VL) below the limits of detection during 6 months or more of highly active antiretroviral therapy (HAART)] are unlikely to be infectious. Questio...

journal_title：HIV medicine

authors： Combescure C,Vallier N,Ledergerber B,Cavassini M,Furrer H,Rauch A,Battegay M,Bernasconi E,Vernazza P,Hirschel B,Swiss HIV Cohort Study.

更新日期：2009-09-01 00:00:00

abstract：OBJECTIVES:Our objective was to identify patient factors associated with being untreated for hepatitis C virus (HCV) infection in HIV-coinfected patients. METHODS:A prospective longitudinal study was carried out. HIV-infected patients with active chronic HCV infection included in the HERACLES cohort (NCT02511496) cons...

journal_title：HIV medicine

authors： Rivero-Juarez A,Tellez F,Castaño-Carracedo M,Merino D,Espinosa N,Santos J,Macias J,Paniagua-García M,Zapata-Lopez A,Collado A,Gómez-Vidal MA,Perez-Stachowski J,Muñoz-Medina L,Fernandez-Fuertes E,Rivero A,Grupo de estudio de

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND:AIDS-related lymphoma (ARL) remains the main cause of AIDS-related deaths in the combined antiretroviral therapy (cART) era. Although most ARLs are associated with the Epstein-Barr virus (EBV), whether patients with high EBV burden are more at risk of developing ARL is unknown. This study investigated the re...

journal_title：HIV medicine

authors： Leruez-Ville M,Seng R,Morand P,Boufassa F,Boue F,Deveau C,Rouzioux C,Goujard C,Seigneurin JM,Meyer L

更新日期：2012-09-01 00:00:00

abstract：OBJECTIVES:To determine whether HIV-infected mothers knew the HIV status of their children, enabling the offer of targeted testing of children at risk. METHODS:All HIV-positive women attending the genitourinary medicine clinic at a district general hospital in the United Kingdom were asked whether they had children an...

journal_title：HIV medicine

authors： Eisenhut M,Sharma V,Kawsar M,Balachandran T

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVES:TMC125-C227, an exploratory phase II, randomized, controlled, open-label trial, compared the efficacy and safety of TMC125 (etravirine) with an investigator-selected protease inhibitor (PI) in nonnucleoside reverse transcriptase inhibitor (NNRTI)-resistant, protease inhibitor-naïve, HIV-1-infected patients. ...

journal_title：HIV medicine

authors： Ruxrungtham K,Pedro RJ,Latiff GH,Conradie F,Domingo P,Lupo S,Pumpradit W,Vingerhoets JH,Peeters M,Peeters I,Kakuda TN,De Smedt G,Woodfall B,TMC125-C227 study group.

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Several studies have compared mitochondrial DNA (mtDNA) content in tissue from HIV-1-infected patients on highly active antiretroviral therapy with and without evidence of lipodystrophy, the diagnosis of which was based on subjective clinical assessment. OBJECTIVES:The aim of this study was to assess the ut...

journal_title：HIV medicine

authors： Casula M,van der Valk M,Wit FW,Nievaard MA,Reiss P

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVES:Few studies have explored the optimal dosing for efavirenz in individuals from China. We investigated plasma efavirenz concentrations and their association with efficacy and tolerance of efavirenz 600 mg daily in Chinese HIV-infected adults. METHODS:An analysis was performed using plasma samples from 455 pa...

journal_title：HIV medicine

authors： Guo F,Cheng X,Hsieh E,Du X,Fu Q,Peng W,Li Y,Song X,Routy JP,Li T

更新日期：2018-05-15 00:00:00

abstract：OBJECTIVE:As a proactive diagnosis of diabetes mellitus (DM) may prevent the onset of severe complications, we used an oral glucose tolerance test (OGTT) to check for impaired glucose tolerance (IGT) and DM in patients with long-standing HIV infection and long durations of exposure to antiretroviral drugs with normal f...

journal_title：HIV medicine

authors： Gianotti N,Visco F,Galli L,Barda B,Piatti P,Salpietro S,Bigoloni A,Vinci C,Nozza S,Gallotta G,Lazzarin A,Castagna A

更新日期：2011-02-01 00:00:00

abstract：OBJECTIVES:Although current guidelines recommend resistance testing prior to antiretroviral therapy (ART) reinitiation after treatment interruptions, virological failure of first-line ritonavir-boosted, protease-inhibitor (PI/r)-containing ART is associated with low emergent PI resistance. In patients experiencing unsc...

journal_title：HIV medicine

authors： Tinago W,O'Halloran JA,O'Halloran RM,Macken A,Lambert JS,Sheehan GJ,Mallon PW

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVES:As more HIV-positive individuals receive antiretroviral therapy (ART), payers are seeking options for covering these increased and sustained drug costs. Strategic use of available generic antiretroviral (ARV) formulations may be feasible. De-simplifying a single-tablet co-formulation (STF) into two or more t...

journal_title：HIV medicine

authors： Krentz HB,Campbell S,Lahl M,Gill MJ

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:In the debate about legalization of euthanasia very little attention has so far been given to the opinion of the patient. OBJECTIVE:To assess the opinion of persons with HIV infection in Europe. METHODS:A cross-sectional survey of persons with HIV infection attending HIV/AIDS treatment centres or HIV suppo...

journal_title：HIV medicine

authors： Andraghetti R,Foran S,Colebunders R,Tomlinson D,Vyras P,Borleffs CJ,Fleerackers Y,Schrooten W,Borchert M

更新日期：2001-01-01 00:00:00

abstract：OBJECTIVES:A significant percentage of patients infected with HIV-1 experience only suboptimal CD4 cell recovery while treated with combination therapy (cART). It is still unclear whether viral properties such as cell tropism play a major role in this incomplete immune response. This study therefore intended to follow ...

journal_title：HIV medicine

authors： Bader J,Schöni-Affolter F,Böni J,Gorgievski-Hrisoho M,Martinetti G,Battegay M,Klimkait T,Swiss HIV Cohort Study.

更新日期：2016-09-01 00:00:00

abstract：OBJECTIVES:Whether treatment-experienced HIV-1-infected patients with an acquired K103N mutation after failing nonnucleoside reverse transcriptase inhibitor (NNRTI) regimens can be treated with rilpivirine is unknown. The aim of this pilot study was to evaluate the efficacy of rilpivirine/tenofovir/emtricitabine in HIV...

journal_title：HIV medicine

authors： Rokx C,Verbon A,Rijnders BJ

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVES:Involvement of people living with HIV (PLHIV) in the design of HIV cure studies is important, given the potential risks to participants. We present results of an international survey of PLHIV to define these issues and inform cure research. METHODS:PLHIV were recruited in June-November 2014 through HIV webs...

journal_title：HIV medicine

authors： Simmons R,Kall M,Collins S,Cairns G,Taylor S,Nelson M,Fidler S,Porter K,Fox J,Collaborative HIV Eradication of viral Reservoirs (CHERUB) Survey collaboration.

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to investigate the association of adiposity with longitudinal kidney function change in 544 HIV-infected persons in the Study of Fat Redistribution and Metabolic Change in HIV infection (FRAM) cohort over 5 years of follow-up. METHODS:The regional distribution of muscle and adipose ...

journal_title：HIV medicine

authors： Malkina A,Scherzer R,Shlipak MG,Bacchetti P,Tien PC,Grunfeld C,Kosmiski L,Peralta CA

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVES:Hepatitis C virus (HCV) has emerged as an important health problem in the era of effective HIV treatment. However, very few data exist on the health status and disease burden of HIV/HCV-coinfected Canadians. METHODS:HIV/HCV-coinfected patients were enrolled prospectively in a multicentre cohort from 16 cent...

journal_title：HIV medicine

authors： Klein MB,Rollet KC,Saeed S,Cox J,Potter M,Cohen J,Conway B,Cooper C,Côté P,Gill J,Haase D,Haider S,Hull M,Moodie E,Montaner J,Pick N,Rachlis A,Rouleau D,Sandre R,Tyndall M,Walmsley S,Canadian HIV-HCV Cohort Inve

更新日期：2013-01-01 00:00:00

abstract：OBJECTIVE:A prospective study was carried out to assess HIV-1 and HIV-2 mother-to-child transmission (MTCT) rates in Portugal between 1999 and 2005 by analysing the proportion of diagnosed infected children born to HIV-positive mothers. MATERIALS AND METHODS:Serial blood samples were collected from 1315 children at ri...

journal_title：HIV medicine

authors： Pádua E,Almeida C,Nunes B,Cortes Martins H,Castela J,Neves C,Paixão MT

更新日期：2009-03-01 00:00:00

abstract：OBJECTIVE:People living with HIV infection are at increased risk for developing cardiovascular disease (CVD). Safe and effective interventions for lowering CVD risk in HIV infection are high priorities. We conducted a prospective, randomized, controlled study to evaluate whether a yoga lifestyle intervention improves C...

journal_title：HIV medicine

authors： Cade WT,Reeds DN,Mondy KE,Overton ET,Grassino J,Tucker S,Bopp C,Laciny E,Hubert S,Lassa-Claxton S,Yarasheski KE

更新日期：2010-07-01 00:00:00

abstract：OBJECTIVES:Rapid HIV testing (RHT) is well established in many countries, but it is new in Australia since a policy change in 2011. We assessed service provider acceptability of RHT before and after its implementation in four Sydney public sexual health clinics. METHODS:Service providers were surveyed immediately afte...

journal_title：HIV medicine

authors： Conway DP,Guy R,McNulty A,Couldwell DL,Davies SC,Smith DE,Keen P,Cunningham P,Holt M,Sydney Rapid HIV Test Study.

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVES:Financial stress has been identified as a barrier to antiretroviral adherence, but only in resource- limited settings. Almost half of HIV-infected Australian adults earn no regular income and, despite highly subsidised antiretroviral therapy and universal health care, 3% of HIV-infected Australians cease ant...

journal_title：HIV medicine

authors： McAllister J,Beardsworth G,Lavie E,MacRae K,Carr A

更新日期：2013-02-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to identify and describe the characteristics of persons born in the UK who acquire HIV infection abroad. METHODS:Analyses using case reports and follow-up data from the national HIV database held at the Health Protection Agency were performed. RESULTS:Fifteen per cent (2066 of 13 8...

journal_title：HIV medicine

authors： Rice B,Gilbart VL,Lawrence J,Smith R,Kall M,Delpech V

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVES:Direct-acting antiviral agents (DAAs) have become the standard of care for the treatment of chronic hepatitis C virus (HCV) infection. We aimed to assess treatment uptake and efficacy in routine clinical settings among HIV/HCV coinfected patients after the introduction of the first generation DAAs. METHODS:...

journal_title：HIV medicine

authors： Schaerer V,Haubitz S,Kovari H,Ledergerber B,Ambrosioni J,Cavassini M,Stoeckle M,Schmid P,Decosterd L,Aouri M,Böni J,Günthard HF,Furrer H,Metzner KJ,Fehr J,Rauch A,Swiss HIV Cohort Study.

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Limited studies have suggested increased incidence rates and unusual clinical presentations of appendicitis among HIV-infected patients during the pre-highly active antiretroviral therapy (HAART) era. Data in the HAART era are sparse, and no study has evaluated potential HIV-related risk factors for the deve...

journal_title：HIV medicine

authors： Crum-Cianflone N,Weekes J,Bavaro M

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVES:Abacavir (ABC) selects for four mutations (K65R, L74V, Y115F and M184V) in HIV-1 reverse transcriptase (RT), both in vitro and during monotherapy in vivo. The aim of this analysis was to compare the selection of these and other nucleoside reverse transcriptase inhibitor (NRTI)-associated mutations by ABC-con...

journal_title：HIV medicine

authors： Lanier ER,Givens N,Stone C,Griffin P,Gibb D,Walker S,Tisdale M,Irlbeck D,Underwood M,St Clair M,Ait-Khaled M

更新日期：2004-11-01 00:00:00

abstract：OBJECTIVES:We assessed whether changes at week 12 in markers of bone turnover, inflammation, and immune activation were associated with clinically important (≥ 5%) bone mineral density (BMD) loss from baseline to week 48 at the proximal femur (hip) and lumbar spine in the SECOND-LINE study. METHODS:We measured concent...

journal_title：HIV medicine

authors： Mwasakifwa GE,Amin J,White CP,Center JR,Kelleher A,Boyd MA

更新日期：2020-09-01 00:00:00

abstract：OBJECTIVES:We provide the first estimate of HIV prevalence among trans and gender-diverse people living in England and compare outcomes of people living with HIV according to gender identity. METHODS:We analysed a comprehensive national HIV cohort and a nationally representative self-reported survey of people accessin...

journal_title：HIV medicine

authors： Kirwan PD,Hibbert M,Kall M,Nambiar K,Ross M,Croxford S,Nash S,Webb L,Wolton A,Delpech VC

更新日期：2021-02-01 00:00:00

abstract：OBJECTIVES:We evaluated the efficacy and tolerability of lamivudine + dolutegravir in a cohort of HIV-1 infected, treatment-experienced patients with undetectable HIV-RNA. METHODS:Time to treatment discontinuation (TD) and virological failure (VF) and their predictors were assessed in a multicenter cohort of HIV-1 inf...

journal_title：HIV medicine

authors： Borghetti A,Baldin G,Lombardi F,Ciccullo A,Capetti A,Rusconi S,Sterrantino G,Latini A,Cossu MV,Gagliardini R,De Luca A,Di Giambenedetto S

更新日期：2018-03-24 00:00:00