CD4:CD8 ratio in children with perinatally acquired HIV-1 infection.

abstract：OBJECTIVES:Pregnant women experience physiological changes during pregnancy that can have a significant impact on antiretroviral pharmacokinetics. Ensuring optimal plasma concentrations of antiretrovirals is essential for maternal health and to minimize the risk of vertical transmission. Here we describe atazanavir/rit...

journal_title：HIV medicine

authors： Else LJ,Jackson V,Brennan M,Back DJ,Khoo SH,Coulter-Smith S,Lambert JS

更新日期：2014-11-01 00:00:00

abstract：OBJECTIVE:To quantify HIV-RNA in plasma, in lymphoid tissue and proviral DNA in peripheral blood mononuclear cells and to relate these to immunological markers among patients with plasma viral load counts of

journal_title：HIV medicine

authors： Katzenstein TL,Ullum H,Røge BT,Wandall J,Dickmeiss E,Barrington T,Skinhøj P,Gerstoft J

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:ODIN (once-daily darunavir in treatment-experienced patients) was a 48-week, phase III, randomized, open-label trial comparing once-daily (qd) darunavir/ritonavir (DRV/r) 800/100 mg with twice-daily (bid) DRV/r 600/100 mg, both with an optimized background regimen [OBR; at least two nucleoside reverse transc...

journal_title：HIV medicine

authors： Sension M,Cahn P,Domingo P,Hodder S,Opsomer M,Lathouwers E,Van de Casteele T,Tomaka F

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVES:Socio-economic factors and lifestyle are known to differ across geographies and populations, which may result in distinct risk profiles for cardiovascular disease (CVD). This study assessed carotid intima-media thickness (CIMT), a proxy for CVD, and its determinants in two groups of people living with HIV (P...

journal_title：HIV medicine

authors： Roozen G,Vos AG,Tempelman HA,Venter W,Grobbee DE,Scheuermaier K,Klipstein-Grobusch K

更新日期：2020-07-01 00:00:00

abstract：OBJECTIVES:There is increasing in vitro and in vivo evidence that reduced zidovudine (ZDV) susceptibility is generated by the selective pressure conferred by other nucleoside reverse transcriptase inhibitors (NRTIs). However, the degree to which this occurs in clinical practice remains unclear. We assessed phenotypic a...

journal_title：HIV medicine

authors： Gilleece Y,Torti C,Mandalia S,Gazzard BG,Pillay D,Pozniak AL

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVES:We provide the first estimate of HIV prevalence among trans and gender-diverse people living in England and compare outcomes of people living with HIV according to gender identity. METHODS:We analysed a comprehensive national HIV cohort and a nationally representative self-reported survey of people accessin...

journal_title：HIV medicine

authors： Kirwan PD,Hibbert M,Kall M,Nambiar K,Ross M,Croxford S,Nash S,Webb L,Wolton A,Delpech VC

更新日期：2021-02-01 00:00:00

abstract：OBJECTIVE:To assess the incidence and consequences of adverse reactions among African HIV-positive pregnant women treated with fixed-dose combinations of a nevirapine-containing antiretroviral (ARV) triple therapy. METHODS:A retrospective analysis of the clinical files of 703 HIV-1-positive pregnant women treated with...

journal_title：HIV medicine

authors： Marazzi MC,Germano P,Liotta G,Guidotti G,Loureiro S,da Cruz Gomes A,Valls Blazquez MC,Narciso P,Perno CF,Mancinelli S,Palombi L

更新日期：2006-07-01 00:00:00

abstract：OBJECTIVES:It has been suggested that chronic hepatitis C virus (HCV) infection depletes mitochondrial DNA (mtDNA) in the liver. Because decreased mtDNA levels were also found in humans infected with HIV, we investigated whether HIV may have aggravated hepatic mtDNA depletion in individuals with HCV infection. METHODS...

journal_title：HIV medicine

authors： Bäuerle J,Laguno M,Mauss S,Mallolas J,Murillas J,Miquel R,Schmutz G,Setzer B,Gatell JM,Walker UA

更新日期：2005-03-01 00:00:00

abstract：OBJECTIVES:The perceived threat of HIV transmission through spitting and biting is evidenced by the increasing use of "spit hoods" by Police Forces in the UK. In addition, a draft parliamentary bill has called for increased penalties for assaults on emergency workers, citing the risk of communicable disease transmissio...

journal_title：HIV medicine

authors： Cresswell FV,Ellis J,Hartley J,Sabin CA,Orkin C,Churchill DR

更新日期：2018-04-23 00:00:00

abstract：OBJECTIVE:To compare virological and immunological responses to nevirapine (NVP)-based and efavirenz (EFV)-based highly active antiretroviral therapy (HAART) regimens in antiretroviral-naïve patients with advanced HIV infection. METHODS:A retrospective observational cohort study was conducted on antiretroviral-naïve H...

journal_title：HIV medicine

authors： Manosuthi W,Sungkanuparph S,Vibhagool A,Rattanasiri S,Thakkinstian A

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to describe the prevalence and correlates of chronic obstructive pulmonary disease (COPD) in a multicentre international cohort of persons living with HIV (PLWH). METHODS:We performed a cross-sectional analysis of adult PLWH, naïve to HIV treatment, with baseline CD4 cell count > 50...

journal_title：HIV medicine

authors： Kunisaki KM,Niewoehner DE,Collins G,Nixon DE,Tedaldi E,Akolo C,Kityo C,Klinker H,La Rosa A,Connett JE,International Network for Strategic Initiatives in Global HIV Trials (INSIGHT) START Study Group.

更新日期：2015-04-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to measure and compare national continuum of HIV care estimates in Europe and Central Asia in three key subpopulations: men who have sex with men (MSM), people who inject drugs (PWID) and migrants. METHODS:Responses to a 2016 European Centre for Disease Prevention and Control (ECDC)...

journal_title：HIV medicine

authors： Brown AE,Attawell K,Hales D,Rice BD,Pharris A,Supervie V,Van Beckhoven D,Delpech VC,An der Heiden M,Marcus U,Maly M,Noori T

更新日期：2018-05-08 00:00:00

abstract：OBJECTIVES:We evaluated the efficacy and tolerability of lamivudine + dolutegravir in a cohort of HIV-1 infected, treatment-experienced patients with undetectable HIV-RNA. METHODS:Time to treatment discontinuation (TD) and virological failure (VF) and their predictors were assessed in a multicenter cohort of HIV-1 inf...

journal_title：HIV medicine

authors： Borghetti A,Baldin G,Lombardi F,Ciccullo A,Capetti A,Rusconi S,Sterrantino G,Latini A,Cossu MV,Gagliardini R,De Luca A,Di Giambenedetto S

更新日期：2018-03-24 00:00:00

abstract：OBJECTIVE:To study the impact of effective highly active antiretroviral therapy (HAART) on the preservation of long-term CD4 memory cells induced by vaccines in HIV-1-infected patients. METHODS:Thirty HIV-1-positive patients on HAART with undetectable viral load were randomized into three groups: 10 received HIV-1 rgp...

journal_title：HIV medicine

authors： Hejdeman B,Leandersson AC,Fredriksson EL,Sandström E,Wahren B,Bratt G

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVES:We describe the management of a cohort of eight HIV-positive patients on antiretroviral medication with evidence of pancreatic insufficiency consisting of chronic diarrhoea and a low faecal elastase measurement. PATIENTS AND METHODS:Twenty-two patients with chronic diarrhoea for whom a faecal elastase measu...

journal_title：HIV medicine

authors： Price DA,Schmid ML,Ong EL,Adjukeiwicz KM,Peaston B,Snow MH

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to describe a UK-wide process to assess adherence to guidelines for the routine investigation and monitoring of HIV-positive adults aged ≥ 50 years and provide clinical services with individual feedback to support improvement in quality of care. METHODS:The British HIV Association (...

journal_title：HIV medicine

authors： Ekong N,Curtis H,Ong E,Sabin CA,Chadwick D,British HIV Association (BHIVA) Audit and Standards Sub-Committee.

更新日期：2020-08-01 00:00:00

abstract：OBJECTIVES:Across Europe, almost a third of individuals infected with HIV do not enter health care until late in the course of their infection. Surveillance to identify the extent to which late presentation occurs remains inadequate across Europe and is further complicated by the lack of a common clinical definition of...

journal_title：HIV medicine

authors： Antinori A,Coenen T,Costagiola D,Dedes N,Ellefson M,Gatell J,Girardi E,Johnson M,Kirk O,Lundgren J,Mocroft A,D'Arminio Monforte A,Phillips A,Raben D,Rockstroh JK,Sabin C,Sönnerborg A,De Wolf F,European Late Presenter

更新日期：2011-01-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to assess indicator condition (IC) guided HIV testing in Estonia from 2012-2015. METHODS:We used Estonian Health Insurance Fund (EHIF) data. EHIF is the core purchaser of health care services in Estonia, covering health care costs for insured people (94% of the total population). Af...

journal_title：HIV medicine

authors： Rüütel K,Lemsalu L,Lätt S,OptTEST by HiE.

更新日期：2018-02-01 00:00:00

abstract：:The 2015 Paediatric European Network for Treatment of AIDS (PENTA) guidelines provide practical recommendations on the management of HIV-1 infection in children in Europe and are an update to those published in 2009. Aims of treatment have progressed significantly over the last decade, moving far beyond limitation of ...

journal_title：HIV medicine

authors： Bamford A,Turkova A,Lyall H,Foster C,Klein N,Bastiaans D,Burger D,Bernadi S,Butler K,Chiappini E,Clayden P,Della Negra M,Giacomet V,Giaquinto C,Gibb D,Galli L,Hainaut M,Koros M,Marques L,Nastouli E,Niehues T,Nog

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Metabolic diseases are frequently observed in HIV-infected persons and, as the risk of contracting these diseases is age-related, their prevalence will increase in the future as a consequence of the benefits of antiretroviral therapy (ART). SUMMARY OF GUIDELINES:All HIV-infected persons should be screened a...

journal_title：HIV medicine

authors： Lundgren JD,Battegay M,Behrens G,De Wit S,Guaraldi G,Katlama C,Martinez E,Nair D,Powderly WG,Reiss P,Sutinen J,Vigano A,EACS Executive Committee.

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVE:To assess adherence to the British HIV Association (BHIVA) 2001 guidelines for the management of HIV-infected pregnant women. METHODS:A survey and a case note review were carried out using structured questionnaires sent to providers of adult HIV care in the UK and Ireland. Participants were women with HIV in...

journal_title：HIV medicine

authors： McDonald C,Curtis H,de Ruiter A,Johnson MA,Welch J,British HIV Association (BHIVA) and the BHIVA audit subcommittee.

更新日期：2006-07-01 00:00:00

abstract：OBJECTIVES:The extent to which highly active antiretroviral therapy (HAART) affects human papillomavirus (HPV) acquisition and clearance in HIV-infected women is not well understood. We sought to describe high-risk HPV detection and clearance rates over time since HAART initiation, based on time-varying HIV viral load ...

journal_title：HIV medicine

authors： Kang M,Cu-Uvin S

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVES:As more HIV-positive individuals receive antiretroviral therapy (ART), payers are seeking options for covering these increased and sustained drug costs. Strategic use of available generic antiretroviral (ARV) formulations may be feasible. De-simplifying a single-tablet co-formulation (STF) into two or more t...

journal_title：HIV medicine

authors： Krentz HB,Campbell S,Lahl M,Gill MJ

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVES:Few studies have explored the optimal dosing for efavirenz in individuals from China. We investigated plasma efavirenz concentrations and their association with efficacy and tolerance of efavirenz 600 mg daily in Chinese HIV-infected adults. METHODS:An analysis was performed using plasma samples from 455 pa...

journal_title：HIV medicine

authors： Guo F,Cheng X,Hsieh E,Du X,Fu Q,Peng W,Li Y,Song X,Routy JP,Li T

更新日期：2018-05-15 00:00:00

abstract：INTRODUCTION:Hyperlipidaemia is a recognized complication of HIV antiretroviral therapy. The interactions among HIV, viral hepatitis, antiretroviral therapies and lipids are poorly understood. METHODS:Ontario HIV Treatment Network Cohort Study participants with at least one lipid level after highly active antiretrovir...

journal_title：HIV medicine

authors： Diong C,Raboud J,Li M,Cooper C,Ontario HIV Treatment Network Cohort Study Team.

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVES:In recent years, new technologies and new approaches to scale up HIV testing have emerged. The objective of this paper was to synthesize the body of recent evidence on strategies aimed at increasing the uptake and coverage of HIV testing outside of health care settings in the European Union (EU)/European Eco...

journal_title：HIV medicine

authors： Croxford S,Tavoschi L,Sullivan AK,Combs L,Raben D,Delpech V,Jakobsen SF,Amato-Gauci AJ,Desai S

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:In the debate about legalization of euthanasia very little attention has so far been given to the opinion of the patient. OBJECTIVE:To assess the opinion of persons with HIV infection in Europe. METHODS:A cross-sectional survey of persons with HIV infection attending HIV/AIDS treatment centres or HIV suppo...

journal_title：HIV medicine

authors： Andraghetti R,Foran S,Colebunders R,Tomlinson D,Vyras P,Borleffs CJ,Fleerackers Y,Schrooten W,Borchert M

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:AIDS-related lymphoma (ARL) remains the main cause of AIDS-related deaths in the combined antiretroviral therapy (cART) era. Although most ARLs are associated with the Epstein-Barr virus (EBV), whether patients with high EBV burden are more at risk of developing ARL is unknown. This study investigated the re...

journal_title：HIV medicine

authors： Leruez-Ville M,Seng R,Morand P,Boufassa F,Boue F,Deveau C,Rouzioux C,Goujard C,Seigneurin JM,Meyer L

更新日期：2012-09-01 00:00:00

abstract：:Despite advances in the treatment of HIV disease, the incidence and mortality of invasive cryptococcal disease remain significant. A matched, case-control study was performed to examine the impact of highly active antiretroviral therapy (HAART) and azole use on the incidence of invasive cryptococcal disease in HIV-inf...

journal_title：HIV medicine

authors： Cantey PT,Stephens DS,Rimland D

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVES:The aim of the study was to determine the factors that may contribute to decreases in bone mineral density (BMD) in patients with AIDS. METHODS:This was a prospective, non-randomized study. Dual X-ray absorptiometry (DXA) was used to determine the BMD of the lumbar spine, femoral neck and distal radius in t...

journal_title：HIV medicine

authors： Rivas P,Górgolas M,García-Delgado R,Díaz-Curiel M,Goyenechea A,Fernández-Guerrero ML

更新日期：2008-02-01 00:00:00