Abstract:
OBJECTIVES:Increased levels of reactive oxygen species lead to oxidative stress. Recent data suggest increased lipid peroxidation (LPO) levels and oxidative stress in periodontitis. Malondialdehyde (MDA), a significant LPO product, increases in oxidative stress. In this study, MDA levels and total oxidant status (TOS) in serum, saliva and gingival crevicular fluid (GCF) were investigated in patients with chronic periodontitis (CP). MATERIALS AND METHODS:Thirty-six CP patients and 28 periodontally healthy controls were included in the study. Following clinical measurements and samplings, MDA and TOS levels were measured by high-performance liquid chromatography and a novel automatic colorimetric method, respectively. RESULTS:While the saliva and GCF MDA levels, and serum, saliva and GCF TOS values were significantly higher in the CP group than the control group (p<0.05), no significant difference in serum MDA levels was found (p>0.05). Strong positive correlations were observed between periodontal parameters and MDA and TOS levels (p<0.05). CONCLUSIONS:The results revealed that LPO significantly increased locally in the periodontal pocket/oral environment, while TOS displayed both systemic and local increases in periodontitis. The findings suggest that increased LPO and TOS may play an important role in the pathology of periodontitis, and are closely related to the clinical periodontal status.
journal_name
J Clin Periodontoljournal_title
Journal of clinical periodontologyauthors
Akalin FA,Baltacioğlu E,Alver A,Karabulut Edoi
10.1111/j.1600-051X.2007.01091.xsubject
Has Abstractpub_date
2007-07-01 00:00:00pages
558-65issue
7eissn
0303-6979issn
1600-051Xpii
CPE1091journal_volume
34pub_type
杂志文章abstract::The present investigation was undertaken to evaluate the periodontal response after resolution of inflammation in a situation of established marginal periodontitis, but in the presence of active, continued tooth hypermobility. Periodontitis was induced unilaterally around mandibular second and third bicuspids in 4 squ...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1983.tb01286.x
更新日期:1983-07-01 00:00:00
abstract::To assess the clinical efficacy of adjunctive supragingival irrigation with buffered 0.3% acetylsalicylic acid (ASA), 60 patients with periodontitis receiving supportive periodontal therapy were randomly assigned to 1 of 3 home regimens: (1) 1x daily adjunctive supragingival irrigation with 300 ml water immediately fo...
journal_title:Journal of clinical periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1111/j.1600-051x.1995.tb00173.x
更新日期:1995-06-01 00:00:00
abstract::An experimental study was designed to compare the claimed antibacterial effect of Betadine and Blend-a-med Fluid with the known plaque growth inhibiting effect of a 0.2% aqueous solution of chlorhexidine digluconate (Hibitane). Before the test perios for 5 days. During the following week they cleaned their teeth mecha...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1976.tb00038.x
更新日期:1976-11-01 00:00:00
abstract::A socio-ecologic conceptual model for periodontal diseases has been proposed. The model, which includes 4 items: health-care organization, human biology, behavioral factors, and environment, has been tested on a random-sample of 50-year-old Oslo citizens. The investigation is based on a clinical examination as well as...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1993.tb00775.x
更新日期:1993-09-01 00:00:00
abstract:AIM:To compare immediate surgery to scaling and root planing (SRP) in the treatment of advanced periodontitis focusing on the prevalence of residual pockets after treatment and cost-effectiveness (1); to elucidate the adjunctive effects of azithromycin in a second-treatment phase (2) up to 36 months. MATERIALS AND MET...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/jcpe.12434
更新日期:2015-08-01 00:00:00
abstract:AIM:The aim of this study was to determine the prevalence and the structure of the leukotoxin promoter region of Actinobacillus actinomycetemcomitans in an ethnic Chinese population. METHOD:Subgingival plaque samples were collected from 42 patients with moderate to advanced periodontitis and 50 periodontally healthy p...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1034/j.1600-051x.2001.028009886.x
更新日期:2001-09-01 00:00:00
abstract:AIM:The aim of this study was to compare peri-implant conditions between fully edentulous (FES) and partially edentulous subjects (PES). MATERIAL AND METHODS:A systematic review was conducted. The MEDLINE, EMBASE and COCHRANE databases were searched for publications up to January 1st 2012. Studies reporting on the ble...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,评审
doi:10.1111/jcpe.12013
更新日期:2013-03-01 00:00:00
abstract:AIM:This study aimed to evaluate the clinical effectiveness of the probiotic Lactobacillus reuteri as an adjunct to non-surgical periodontal therapy (NSPT). MATERIALS AND METHODS:A double-blind, paralleled-arm, placebo-controlled and randomized clinical trial was conducted. Probiotics L. reuteri or placebo lozenges we...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1111/jcpe.13191
更新日期:2019-12-01 00:00:00
abstract:AIM:This study analysed the status of DNA methylation in the promoter region of the IL8 gene in oral mucosa cells from healthy, smoker and non-smoker subjects with chronic periodontitis and compared these findings among groups with mRNA levels. MATERIAL AND METHODS:Genomic DNA from epithelial oral cells of 41 healthy ...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051X.2009.01446.x
更新日期:2009-09-01 00:00:00
abstract::Periodontal disease indicators were evaluated according to the periodontal treatment need system (PTNS) in random samples of 35-year-old citizens of Oslo in 1973 and 1984. The study indicated that although periodontal disease was a common finding in both samples, there was a significant reduction in score C (indicatin...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1990.tb00021.x
更新日期:1990-04-01 00:00:00
abstract::The amount of plaque accumulation was assessed in an intraindividual study comprising 10 individuals. During different 2-week periods, the test subjects used nylon floss (unwaxed, waxed and specially treated), silk floss (unwaxed and waxed), Superfloss or triangular toothpicks for interdental tooth cleaning. Only teet...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1980.tb02158.x
更新日期:1980-12-01 00:00:00
abstract::Periodontitis is generally considered to be a consequence of an unfavourable host-parasite interaction in which bacteria are the determinants of disease. An intense search continues for the bacteria, specific or non-specific, that are responsible for periodontitis and various forms of the periodontal diseases have bee...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,评审
doi:10.1111/j.1600-051x.1995.tb00125.x
更新日期:1995-02-01 00:00:00
abstract:AIM:To investigate the prevalence of tetM, tetQ, nim and bla(TEM) antimicrobial resistance genes in subgingival and tongue samples of Greek subjects. MATERIALS AND METHODS:Fifty-four subjects participated in the present study. Participants each contributed with one pooled subgingival sample from the mesiobuccal surfac...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051X.2009.01425.x
更新日期:2009-07-01 00:00:00
abstract:AIM:The purpose of this study was to evaluate the relationship between periodontal disease and general health status in community-dwelling elderly using serum albumin concentration as a criterion index of the severity of an underlying disease and nutrition status. METHODS:Serum albumin level was detected by the bromcr...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051X.2005.00901.x
更新日期:2006-05-01 00:00:00
abstract:OBJECTIVE:To compare the clinical outcomes related to implants following lateral augmentation procedures (GBR, bone grafts, split osteotomy) with implants placed in pristine sites. MATERIAL AND METHODS:A systematic review of all prospective studies of implants placed simultaneously or as a second surgery following lat...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,meta分析,评审
doi:10.1111/j.1600-051X.2008.01269.x
更新日期:2008-09-01 00:00:00
abstract::Dental caries and periodontal disease are common in industrialized countries and caries is increasing in non-industrialized countries. The predominant method of coping with the disease problem has been to treat rather than prevent the diseases, an approach which has obviously failed to cope with the problem as shown b...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1979.tb02113.x
更新日期:1979-12-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to investigate the association between serum lipids and periodontal infection and the role of serum lipids in the association between body weight and periodontal infection. MATERIAL AND METHODS:The Health 2000 Health Examination Survey, which included 8028 subjects aged 30 or older l...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051X.2008.01331.x
更新日期:2008-12-01 00:00:00
abstract:OBJECTIVES:The study aimed at evaluating the 2-year results obtained following combined surgical resective and regenerative treatment of advanced peri-implantitis defects comparing two methods of surface debridement/decontamination (DD). MATERIAL & METHODS:Twenty-four patients (n = 26 combined supra- and intrabony def...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1600-051X.2012.01867.x
更新日期:2012-08-01 00:00:00
abstract::A companion study reported that new connective tissue attachment did not occur to a surgically denuded root surface when transplanted into a normal periodontium. It was the purpose of this study to evaluate periodontal healing adjacent to a citric acid treated denuded root surface. In four squirrel monkeys, 12 teeth w...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1982.tb02105.x
更新日期:1982-11-01 00:00:00
abstract::The present study evaluates the healing of an experimental standardized full thickness excisional wound in the palate of a sialadenectomized rat model. Experimental rats underwent sialadenectomy of the submandibular and sublingual glands and ligation of the parotid ducts. A full thickness circular wound, 3 mm in diame...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1992.tb00657.x
更新日期:1992-05-01 00:00:00
abstract::This study compared oral irrigation and rinsing with chlorhexidine (CHX) and placebo in the treatment of naturally occurring chronic gingivitis. 44 subjects with at least 6 interproximal sites which bled on probing were randomly distributed on a double-blind basis into 4 treatment groups, placebo-rinse, CHX-rinse (0.1...
journal_title:Journal of clinical periodontology
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1990-09-01 00:00:00
abstract:OBJECTIVES:To determine the plaque-removing ability of a Sonicare Plus electric toothbrush in an in vitro model. MATERIAL AND METHODS:Multispecies oral biofilms derived from human saliva were grown on hydroxyapatite discs in a constant-depth film fermenter. The biofilms were placed in a typodont model so that they mim...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1034/j.1600-051x.2003.00307.x
更新日期:2003-07-01 00:00:00
abstract:AIMS:The aims of this study were to evaluate the effect of mechanical periodontal treatment with local application of minocycline (APT) on serum adiponectin as a marker of insulin resistance improvement in type 2 diabetes mellitus (T2DM) patients and to investigate if effect of APT on serum adiponectin level was sustai...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章,随机对照试验
doi:10.1111/j.1600-051X.2008.01359.x
更新日期:2009-02-01 00:00:00
abstract:AIM:The pathophysiology of periodontal diseases involves aspects of immunity and bone remodelling. Considering the role of the kinin B1 receptor (Bdkrb1) in inflammation and healing, the purpose of this study was to evaluate the contribution of Bdkrb1 to the pathogenesis of periodontitis. MATERIAL AND METHODS:We used ...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/jcpe.12097
更新日期:2013-07-01 00:00:00
abstract:AIM:To identify the molecular mechanisms mediating the persistent defensive functions of the self-renewing junctional epithelium (JE). MATERIALS AND METHODS:Two strains of Wnt reporter mice, Axin2CreErt2/+ ;R26RmTmG/+ and Axin2LacZ/+ , were employed, along with three clinically relevant experimental scenarios where th...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/jcpe.13371
更新日期:2020-12-01 00:00:00
abstract:AIM AND BACKGROUND:The position of the most apical inter-dental portion of the alveolar crest is classically used in osseous resective surgery (ORS) to establish the amount of the inter-proximal and buccal/lingual bone resection. Supracrestal fibres connected to the root cementum are always present coronal to the alveo...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051X.2006.01027.x
更新日期:2007-02-01 00:00:00
abstract:AIM:The aim of this study was to assess the use of a micro-brush to remove plaque deposits from subgingival, periodontally involved root surfaces in vivo. METHODS:30 periodontally involved teeth requiring extraction for periodontal or prosthetic reasons in 26 adult patients were utilised. For inclusion, teeth had to d...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1034/j.1600-051x.2001.028009820.x
更新日期:2001-09-01 00:00:00
abstract::The subgingival microflora was assessed by means of dark field microscopy in 106 pockets of 47 subjects with long-term insulin-dependent diabetes mellitus (IDD). The microbiota of 55 healthy sulci (probing depth < 4 mm) and 51 periodontally diseased (probing depth > or = 4 and 6 mm) pockets were analyzed. The mean dur...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1996.tb00536.x
更新日期:1996-02-01 00:00:00
abstract::The purpose of this study was to document and characterize epithelial remnants (EPRs) of the crestal periodontium of the deciduous dentition of a diphyodont and compare them with EPR units found in the corresponding area of the permanent dentition. 7 beagle dogs were used. At the age of 10 weeks (deciduous dentition) ...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/j.1600-051x.1994.tb00754.x
更新日期:1994-10-01 00:00:00
abstract:AIM:In this study, we investigated the effect of differences in periodontal status in the masticatory performance of dentate subjects with the same occlusal supporting area. MATERIALS AND METHODS:The subjects of the analysis were classified into those of Eichner A1-3 (n = 1094) and Eichner B1-4 (n = 529). Subjects' pe...
journal_title:Journal of clinical periodontology
pub_type: 杂志文章
doi:10.1111/jcpe.12241
更新日期:2014-05-01 00:00:00