Conversion from cyclosporine-based immunosuppression to tacrolimus/mycophenolate mofetil in patients with refractory and ongoing acute renal allograft rejection.

abstract：BACKGROUND:Chronic nephrotoxic effects of calcineurin inhibitors may be responsible for late allograft dysfunction and reduced allograft half-life. Mammalian target of rapamycin inhibitors (mTOR-i's), a newer class of immunosuppressant, do not have the chronic nephrotoxic effects shown with calcineurin inhibitors (CNI)...

journal_title：Annals of transplantation

authors： Toz H,Sen S,Celik HA,Yilmaz M,Hur E,Hoscoskun C,Ozkahya M,Aydin HH

更新日期：2011-04-01 00:00:00

abstract：BACKGROUND:Induction of the hepatic and intestinal cytochrome P450-3A4 system and intestinal P-glycoprotein is an unavoidable consequence of rifampin administration which requires substantial increase in tacrolimus dose when given concurrently. Chronic diarrhea is known to precipitate tacrolimus toxicity irrespective o...

journal_title：Annals of transplantation

authors： Abdel Halim M,Al-Otaibi T,Gheith O,El-Kholy O,Abdel Tawab K,Said T,Nair P,Nampoory MR

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Institut Georges Lopez-1 (IGL-1) is a new preservation solution with lower potassium and lower viscosity than University Wisconsin solution (UW). These characteristics which improve liver preservation lead us to evaluate clinical effects of IGL-1 in a randomized controlled study with UW. MATERIAL/METHODS:Fr...

journal_title：Annals of transplantation

authors： Dondéro F,Paugam-Burtz C,Danjou F,Stocco J,Durand F,Belghiti J

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Pseudoaneurysm is a very rare and unusual form of myocardial rupture, with complications such as chest trauma, inflammation, acute myocardial infarction, and infection. Although this rare complication has already been reported, it has never been found in a transplanted patient. CASE REPORT:We present the ca...

journal_title：Annals of transplantation

authors： Urbanowicz T,Katarzyński S,Puślecki M,Budniak W,Araszkiewicz A,Łanocha M,Pyda M,Straburzyńska-Migaj E,Jemielity M

更新日期：2014-06-26 00:00:00

abstract：:Organ transplantation program has been slowly developing over last 30 years. The number of DD (deceased donors) stabilized on the level of approximately 13/million of population. Multiorgan donation has been 45%, due to some problems with donor management. Polish Transplant Coordinating Center POLTRANSPLANT which is r...

journal_title：Annals of transplantation

authors： Czerwinski J,Antoszkiewicz K,Malanowski P,Durlik M,Kaliciński P,Lisik W,Wałaszewski J,Rowiński W

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Sulforaphane is a naturally occuring antioxidative and anti-inflammatory isothiocyanat. In this study, its impact on experimental kidney transplantation was evaluated. MATERIAL AND METHODS:Male Brown Norway rats (n=112) were used as experimental animals. Donor kidneys were harvested and stored for 12 hours ...

journal_title：Annals of transplantation

authors： Cekauskas A,Bruns H,Manikas M,Herr I,Gross ML,Zorn M,Jankevicius F,Strupas K,Schemmer P

更新日期：2013-09-18 00:00:00

abstract：BACKGROUND:Transplantation is the only effective method of treatment for end-stage and acute liver failure. Increased average survival time has been observed, and results from improved surgical technique and amended immunosuppression protocols. However, longer survival of patients after orthotopic liver transplantation...

journal_title：Annals of transplantation

authors： Rongies W,Stepniewska S,Lewandowska M,Smolis-Bak E,Dolecki W,Sierdzinski J,Trzepla E,Cholewinska G,Stankiewicz W

更新日期：2011-07-01 00:00:00

abstract：:Aim of this monocentric study is to compare the outcome of 101 renal transplants performed in patients older than 55 years with single kidney retrieved from donors older than 50 years, with 263 transplants performed in patients younger than 55 years transplanted with young kidneys. Delayed graft function (DGF) had sim...

journal_title：Annals of transplantation

authors： Bertoni E,Rosati A,Zanazzi M,Di Maria L,Becherelli P,Gallo M,Salvadori M

更新日期：2004-01-01 00:00:00

abstract：:BACKGROUND Correction of hypovitaminosis D is simple, but it is unclear whether it is associated with an accelerated decline of renal allograft function in pediatric renal transplantation patients. This retrospective single center cohort study aimed at analyzing the effect of vitamin D and covariates on the slope of 1...

journal_title：Annals of transplantation

authors： Wile B,Yoo E,Alvarez Elias AC,Subramanian L,Eager K,Sharma AP,Filler G

更新日期：2018-04-17 00:00:00

abstract：:Transplantation of hands in humans has become an accepted therapeutic modality. A hand transplant is composed of various tissues of different degree of immunogenicity. In addition, skin contains own resident bacterial flora that may become virulent in the ischemic and rejecting graft. Discrimination between skin rejec...

journal_title：Annals of transplantation

authors： Cakala M,Olszewski WL

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:The impact of treated preoperative bacterial infections on the outcome of living-donor liver transplantation (LDLT) is not well defined. The aim of this study was to determine the frequency of pre-transplant bacterial infections within one month before LDLT and their impact on the post-transplant morbidity a...

journal_title：Annals of transplantation

authors： Hara T,Soyama A,Takatsuki M,Hidaka M,Carpenter I,Kinoshita A,Adachi T,Kitasato A,Kuroki T,Eguchi S

更新日期：2014-12-23 00:00:00

abstract：:BACKGROUND Inflammatory activity of the artery can be assessed by measuring 18F-fluorodeoxyglucose (18F-FDG) uptake with positron emission tomography computed tomography (PET/CT). Improvement in vascular function after renal transplantation has been reported, but no studies have used 18F-FDG PET/CT to examine the chan...

journal_title：Annals of transplantation

authors： Yoon HE,Kim Y,Kim SD,Oh JK,Chung YA,Shin SJ,Yang CW,Seo SM

更新日期：2018-06-15 00:00:00

abstract：BACKGROUND:Morbid obesity is associated with liver pathology, most commonly non-alcoholic steatohepatitis (NASH) leading to cirrhosis. However, the morbid obesity impedes qualification for organ transplantation. CASE REPORT:We present a case report of a 56-year-old woman who underwent bariatric procedure followed by l...

journal_title：Annals of transplantation

authors： Marszałek R,Ziemiański P,Łągiewska B,Pacholczyk M,Domienik-Karłowicz J,Trzebicki J,Wierzbicki Z,Jankowski K,Kosieradzki M,Wasiak D,Jonas M,Pruszczyk P,Durlik M,Lisik W,Chmura A

更新日期：2015-02-25 00:00:00

abstract：BACKGROUND:Organ transplantation increases the risk of cancer including lymphomas through various and insidious mechanisms. In this study, we aimed to gather and analyze data of 5 international studies on late onset lymphoproliferative disorders after renal and liver transplantation. MATERIAL/METHODS:We conducted a co...

journal_title：Annals of transplantation

authors： Khedmat H,Taheri S

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Galectins are a family of soluble lectins expressed in a variety of tissues, which play many important regulatory roles in inflammation, immunity, and cancer. The up-regulation of galectin-3 in hypertrophied hearts and the development of fibrosis have been shown in experimental studies. Increased galectin-3 ...

journal_title：Annals of transplantation

authors： Beiras-Fernandez A,Weis F,Rothkopf J,Kaczmarek I,Ledderose C,Dick A,Keller T,Beiras A,Kreth S

更新日期：2013-11-22 00:00:00

abstract：OBJECTIVES:Aim of the study was to assess frequency and risk factors of steroid resistant cellular rejection (SRR) in heart transplant recipients, to determine methods of its treatment, and to evaluate influence of steroid resistant rejection and method of its treatment on short- and long-term results. METHODS:All pts...

journal_title：Annals of transplantation

authors： Zakliczyński M,Nozyński J,Zakliczyńska H,Kozłowska K,Trzcińska I,Szewczyk M,Konecka-Mrówka D,Foremny J,Swierad M,Przybylski R,Pisarska H,Wojarski J,Durmała J,Zembala M

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Early initiation of enteral nutrition is recommended after some surgical procedures. This study retrospectively analyzed the effects of addition of early enteral nutrition (EEN) support during the postoperative phase in patients after living-donor liver transplantation (LDLT). MATERIAL AND METHODS:The subje...

journal_title：Annals of transplantation

authors： Ei S,Shinoda M,Itano O,Obara H,Kitago M,Hibi T,Yagi H,Abe Y,Matsubara K,Ono Y,Kawachi S,Hoshino K,Kuroda T,Tanabe M,Kitagawa Y

更新日期：2015-06-25 00:00:00

abstract：:BACKGROUND Autologous stem cell transplantation (ASCT) has become a standard procedure in multiple myeloma (MM) patients. Cryopreservation (CRYO) of stem cells may be associated with adverse reactions of dimethyl sulfoxide. Previous studies showed that stem cell storage at 4°C (non-cryopreserved [NC] method) may have ...

journal_title：Annals of transplantation

authors： Piriyakhuntorn P,Tantiworawit A,Rattanathammethee T,Hantrakool S,Chai-Adisaksopha C,Rattarittamrong E,Norasetthada L

更新日期：2020-12-11 00:00:00

abstract：:The use of xenografts could relieve the chronically inadequate supply of human organs for transplantation, but doubts have been expressed about the general acceptability of transplanting animal organs into human. Some researchers and clinicians have chosen to ignore negative attitudes towards clinical xenotransplantat...

journal_title：Annals of transplantation

authors： Mohacsi PJ,Thompson JF,Quine S

更新日期：1998-01-01 00:00:00

abstract：:For each individual, there is a limit to the capacity to perform exercise. The limitation, however, depends on the nature of the task and is also influenced by a number of other factors. Muscle strength is determined largely by muscle mass, specifically muscle cross-sectional area, but is also influenced by neural dri...

journal_title：Annals of transplantation

authors： Maughan RJ

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:The early phase of MPA exposure has rarely been investigated after solid organ transplantation, especially in heart transplantation patients. We evaluated the association between exposure to mycophenolic acid (MPA), a main metabolite of mycophenolate mofetil (MMF), and clinical events within 3 months after h...

journal_title：Annals of transplantation

authors： Roan JN,Chou CH,Hsu CH,Wu SY,Huang YC,Yang YJ,Luo CY

更新日期：2013-02-05 00:00:00

abstract：:BACKGROUND Acute graft-versus-host disease (aGVHD) remains the most common and challenging complication after allogeneic hematopoietic stem cell transplantation (allo-HSCT). An important obstacle to the therapeutic effect of aGVHD is the inability to identify risk factors for an individual patient at the onset of symp...

journal_title：Annals of transplantation

authors： Wang F,Cai B,Wang L,Gu Z,Luo L,Wei H,Zhao S,Guan L,Wang X,Wang L,Liu D,Gao C

更新日期：2017-02-03 00:00:00

abstract：:Ano-genital neoplasia is about 20 x more common in renal transplant patients than the general population. Neoplasms in the immunosuppressed are more morbid and mortal because: patients are younger; tumors are more undifferentiated; they have more and larger foci; more sites are involved; neoplasms tend to persist, rec...

journal_title：Annals of transplantation

authors： Sillman FH,Sentovich S,Shaffer D

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:This retrospective single-center study was undertaken to assess the occurrence of de novo neoplasms in renal transplant recipients according to the immunosuppressive regimen and time after transplantation. MATERIAL/METHODS:Observation encompassed 1028 patients transplanted between the years 1983-2006 and fo...

journal_title：Annals of transplantation

authors： Watorek E,Boratynska M,Smolska D,Patrzalek D,Klinger M

更新日期：2011-04-01 00:00:00

abstract：OBJECTIVES AND METHODS:Brain death related hemodynamic instability and/or cardiac dysfunction is frequently described in the potential organ donor which may lead to exclusion of the heart from transplantation. The underlying mechanisms are controversely discussed. Therefore, in the present study, potential brain death ...

journal_title：Annals of transplantation

authors： Szabó G,Hackert T,Buhmann V,Sebening C,Vahl CF,Hagl S

更新日期：2000-01-01 00:00:00

abstract：:Ischemic reperfusion injury is a complex pathophysiological event associated with significant impairment of multiple vascular and cellular responses. Oxidative damage due to the presence of radical oxygen species is the essential step that initiates a wide range of intracellular stress signaling processes that culmina...

journal_title：Annals of transplantation

authors： Toledo-Pereyra LH,Lopez-Neblina F,Toledo AH

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Autologous peripheral blood stem cell transplantation (PBSCT) is commonly used in the treatment of lymphoma patients. G-CSF is widely used to boost white blood cell recovery. However, there are no clear data indicating which strategy of using G-CSF provides the most benefit. The aim of our study was to compa...

journal_title：Annals of transplantation

authors： Wyleżoł I,Snarski E,Markiewicz M,Kyrcz-Krzemień S,Jędrzejczak WW,Walewski J

更新日期：2013-07-02 00:00:00

abstract：:BACKGROUND Minimally invasive surgery (MIS) has rapidly advanced, but its use in transplant patients has lagged. We share our experience of MIS for patients after kidney and liver transplantation and compare our results with similar studies in the literature. MATERIAL AND METHODS This study included 14 MIS (12 laparos...

journal_title：Annals of transplantation

authors： Hsu DW,Chang CM,Hsu CS,Yin WY

更新日期：2020-06-16 00:00:00

abstract：UNLABELLED:In spite of progress in biotechnology, isolation of porcine pancreatic islets remains a difficult task with unpredictable results. One reason could be the lack of knowledge as to the expression of extracellular matrix proteins in porcine exocrine and endocrine tissues, particularly in "islet capsules". Such ...

journal_title：Annals of transplantation

authors： Meyer T,Czub S,Chodnewska I,Beutner U,Hamelmann W,Klöck G,Zimmermann U,Thiede A,Ulrichs K

更新日期：1997-01-01 00:00:00

abstract：:Recovery of the patients after transplantation of non-renal organs may be complicated by multi-faceted chronic renal failure (CKD) which is regarded as an independent risk factor of graft dysfunction and mortality. The occurrence of CKD in non-renal transplant recipients depends mainly on a type of transplanted organ,...

journal_title：Annals of transplantation

authors： Nowicki M,Zwiech R

更新日期：2005-01-01 00:00:00