Abstract:
:Tendons and ligaments are related connective tissues that join muscle to bone and bone to bone, respectively. Tendon and ligament injuries are widely distributed clinical problems in society and while healing of such disorders can occur, the original biological properties of the tissue do not return to normal. In this review, recent work on tendon and ligament development and the use of growth factors for successful cellular therapy of tendon and ligament disorders are discussed. In addition, anti-inflammatory concepts for the treatment of tendon and ligament injuries and recent developments in stem cell engineering for tendon and ligament tissues are examined. Lastly, gene transfer strategies for therapeutic applications to heal tendon and ligament disorders are reviewed.
journal_name
Regen Medjournal_title
Regenerative medicineauthors
Hoffmann A,Gross Gdoi
10.2217/17460751.1.4.563subject
Has Abstractpub_date
2006-07-01 00:00:00pages
563-74issue
4eissn
1746-0751issn
1746-076Xjournal_volume
1pub_type
杂志文章,评审abstract::Latest developments in the field of stem cell research and regenerative medicine compiled from publicly available information and press releases from nonacademic institutions in March 2020. ...
journal_title:Regenerative medicine
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abstract:AIMS:An extensive colonization of surgical meshes with autologous fibroblasts may reduce complications. Therefore, we aimed to establish a technique that allows isolation and propagation of fibroblasts from vaginal biopsies. Using these cells we tested the applicability of several clinically applied meshes for fibrobla...
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abstract::Diabetes mellitus represents a global epidemic affecting over 350 million patients worldwide and projected by the WHO to surpass the 500 million patient mark within the next two decades. Besides Type 1 and Type 2 diabetes mellitus, the study of the endocrine compartment of the pancreas is of great translational intere...
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abstract:AIMS:To investigate neural stem cell (NSC) interactions with striatal tissue following engraftment and the effects of growth factors. MATERIALS & METHODS:Organotypic striatal slice cultures established from neonatal rats were used as an ex vivo model system. Survival, integration and differentiation of grafted NSCs fr...
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journal_title:Regenerative medicine
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journal_title:Regenerative medicine
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journal_title:Regenerative medicine
pub_type: 杂志文章,评审
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journal_title:Regenerative medicine
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journal_title:Regenerative medicine
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journal_title:Regenerative medicine
pub_type: 杂志文章
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journal_title:Regenerative medicine
pub_type: 杂志文章
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journal_title:Regenerative medicine
pub_type: 杂志文章,评审
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journal_title:Regenerative medicine
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journal_title:Regenerative medicine
pub_type: 杂志文章,评审
doi:10.2217/17460751.2.4.425
更新日期:2007-07-01 00:00:00
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更新日期:2011-11-01 00:00:00
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journal_title:Regenerative medicine
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更新日期:2007-01-01 00:00:00
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abstract::Aim: We aim to show that the use of nondigested micro-fragmented adipose tissue (MFat™, Lipogems®) is a viable alternative for treatment of joint pain and inflammation associated dysfunction in shoulder osteoarthritis (OA). Materials & methods: A total of 25 subjects with OA received an injection of MFat™ and were fol...
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