Abstract：
AIMS:To assess knowledge of colorectal cancer (CRC) symptoms among outpatient attendees, and to review disease stage, presentation and duration of symptoms in patients diagnosed with CRC. METHODS:A questionnaire survey was used to evaluate knowledge of symptoms of CRC and other malignancies. A review of patients diagnosed with CRC during a two-year period was performed. RESULTS:Of 350 survey participants 26.6% could name a CRC symptom, compared to 53.4% for lung cancer and 71.5% for breast cancer. Of 102 patients diagnosed with CRC 3.9% had Dukes A disease, 32.4% had Dukes B, 39.2% had Dukes C and 24.5% had distant metastases. Forty per cent of patients presented acutely. The mean duration of symptoms was 24 weeks. CONCLUSIONS:Knowledge of CRC symptoms is poor and is reflected in the percentage of late stage and emergency presentations. Increasing public awareness of CRC may lead to earlier presentation and improved survival.
journal_name
Ir J Med Scijournal_title
Irish journal of medical scienceauthors
Manning AT,Waldron R,Barry Kdoi
10.1007/BF03167968subject
Has Abstractpub_date
2006-10-01 00:00:00pages
55-7issue
4eissn
0021-1265issn
1863-4362journal_volume
175pub_type
杂志文章abstract：INTRODUCTION:The amino acid taurine has an established role in attenuating lung fibrosis secondary to bleomycin-induced injury. This study evaluates taurine's effect on TGF-beta1 expression and the development of lung fibrosis after single-dose thoracic radiotherapy. METHODS:Four groups of C57/Bl6 mice received 14 Gy ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-009-0389-2
更新日期：2010-03-01 00:00:00
abstract：:Management of subcutaneous insulin resistance remains a difficult problem which can be treated by administering insulin intravenously by means of infusion pumps. We wish to report the case of a 31 year old primigravida with subcutaneous insulin resistance who developed a hitherto undescribed clinical complication of c...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02943015
更新日期：1994-02-01 00:00:00
abstract：:The Dublin Soft Tissue Sarcoma Panel was established in 1989 with a view to achieving a unified approach to diagnosis and management of soft tissue and visceral sarcomas. This interim report presents data on 265 prospectively-evaluated patients and on a separate retrospective series of 126 patients. The patients in th...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02943260
更新日期：1994-05-01 00:00:00
abstract：BACKGROUND:Suicidal behaviour has become recognised as a major public health problem. AIM:To examine hospital-treated parasuicide and suicide in the Southern and Mid-Western Health Boards. METHODS:Parasuicide data were derived from independent data collection in general and psychiatric hospitals and prisons between 1...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02914492
更新日期：2003-07-01 00:00:00
abstract：BACKGROUND:Patients' awareness of the increased cardiovascular risk associated with their diabetes is poorly documented. AIM:The aim of this study was to assess the awareness of diabetes complications among patients with diabetes in Ireland. METHODS:Patients attending diabetes outpatient clinics in two teaching hospi...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-009-0301-0
更新日期：2009-12-01 00:00:00
abstract：BACKGROUND:Hypertension (HT) is a disease associated with endothelial dysfunction which is related to some adipokines and pro- and anti-inflammatory cytokines. AIMS:Our aim was to investigate roles of apelin, omentin-1, and vaspin in essential HT and to evaluate their relationships with other pro- and anti-inflammator...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-020-02272-w
更新日期：2021-02-01 00:00:00
abstract：INTRODUCTION:The case report is the cornerstone of both medical teaching and writing. However, during recent years the value of the case report has been questioned, so much so that it has been abandoned by many journals. The aim of this study was to assess case reports published by the Irish Journal of Medical Science ...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/s11845-010-0649-1
更新日期：2011-06-01 00:00:00
abstract：PURPOSE:The purpose of this study is to introduce peer teaching of communication skills to first-year anaesthesia trainees in Ireland and to evaluate their perception of this teaching modality. METHODS:Seventy-nine first-year anaesthesia trainees participated in a novel peer-led communication skills programme over a 2...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-017-1637-5
更新日期：2018-02-01 00:00:00
abstract：:Changes in endothelial cell (EC) morphology occur at sites of physiological lymphocyte traffic and in areas of chronic inflammation. Previous studies have shown that EC shape changes also occur in vitro following exposure of EC monolayers to peripheral blood mononuclear cell (PBMC)-derived conditioned media (CM). In t...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02942828
更新日期：1994-08-01 00:00:00
abstract：BACKGROUND:Low birth weight (LBW) is a leading cause of infant mortality and morbidity, and a specific risk for the development of neuro-developmental and academic problems. AIM:To examine the medical, cognitive and academic outcomes of VLBW (<1,500 g) children, born in one maternity hospital in Dublin between 1995 an...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-013-1040-9
更新日期：2014-12-01 00:00:00
abstract：:More than 300 risk factors for coronary artery disease (CAD) have been described. There are important geographical and racial differences in both the prevalence of CAD and of potential risk factors. The purpose of this study was to determine the relationship between both the presence and extent of angiographically def...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02943801
更新日期：1996-04-01 00:00:00
abstract：BACKGROUND:The survey of lifestyles, attitudes and nutrition (SLAN) is a national representative sample of 6,539 adults. AIMS:To report on both global and disease specific measures of self-reported morbidity according to age, gender and medical card status. METHODS:Reported rates of morbidity are given for angina, he...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03170499
更新日期：2002-07-01 00:00:00
abstract：:A case of cervical pregnancy resulting in intra abdominal rupture in the first trimester is reported. The clinical features of this rare cause of uterine rupture are outlined. Pathological examination of the uterus showed placenta percreta. ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02942011
更新日期：1989-01-01 00:00:00
abstract：BACKGROUND:Gallbladder stone with symptom is an indication of cholecystectomy according to the current guideline. However, about 80% of gallstone patients are asymptomatic. The identification of gallbladder stone patients likely to develop symptomatic complications would be of benefit in clinical practice. AIMS:The ai...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-019-02161-x
更新日期：2020-08-01 00:00:00
abstract：INTRODUCTION:Heparin-induced thrombocytopenia syndrome (HITS) is an infrequent complication of heparin anticoagulation. CASE REPORT:We present the case of a 44-year-old male who was admitted with acute ischaemia of his right lower limb. He was initially treated with unfractionated heparin and thrombolysis, but subsequ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-010-0531-1
更新日期：2012-09-01 00:00:00
abstract：:Percutaneous tracheostomy (PCT) facilitates easy, bedside insertion of a tracheostomy tube. The percutaneous approach to tracheostomy is used in some parts of the world. This is the first report of a PCT method, in Ireland. The percutaneous technique appears to have advantages over conventional, surgical tracheostomy....
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02996321
更新日期：1993-10-01 00:00:00
abstract：:Total hip arthroplasty (THA) is an effective and durable treatment option for hip osteoarthritis (OA). As life expectancy continues to increase, so too will the demand for joint arthroplasty in the 10th decade of life, frequently in cases involving osteoarthritis of both hips. Simultaneous bilateral total hip arthropl...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/s11845-017-1572-5
更新日期：2017-11-01 00:00:00
abstract：:A questionnaire survey was carried out to estimate activity levels in a sample of 784 men and women aged 35 to 64 years in County Kilkenny, Ireland. Men were more likely to have sedentary, heavy or very heavy work activity while the majority of women had moderate activity during an average day. Only a small minority o...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF02950440
更新日期：1991-01-01 00:00:00
abstract：:Approximately one-third of patients with Crohn's disease have a distinct fibrostenosing phenotype predisposing them to recurrent intestinal stricture formation. The intestinal fibroblast was thought to play a critical role in the abnormal wound healing which ends in stricture formation. Recognising this, a laboratory-...
journal_title：Irish journal of medical science
pub_type： 传,历史文章,杂志文章,评审
doi：10.1007/s11845-018-1850-x
更新日期：2018-11-01 00:00:00
abstract：BACKGROUND:Understanding the impact of a publication by using bibliometric indices becomes an essential activity not only for universities and research institutes but also for individual academicians. This paper aims to provide a brief review of the current bibliometric tools used by authors and editors and proposes an...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/s11845-018-1936-5
更新日期：2019-08-01 00:00:00
abstract：AIMS:Many studies have suggested Cytomegalovirus infection might be implicated in steroid-refractory inflammatory bowel disease (IBD), in which situation management is extremely difficult. CMV infection being a potential cause of IBD have drawn great attention of clinicians, with insufficient evidence to reach conclusi...
journal_title：Irish journal of medical science
pub_type： 杂志文章,meta分析
doi：10.1007/s11845-018-1752-y
更新日期：2018-11-01 00:00:00
abstract：BACKGROUND:Over the last decade there have been significant changes in the prescribing of antidiabetic therapies. It is of interest to know about these trends and variations in the Irish population so that future prescribing patterns can be estimated. AIMS:To examine the trends in prescribed antidiabetic treatments, i...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-013-1011-1
更新日期：2014-06-01 00:00:00
abstract：BACKGROUND:Ankylosing spondylitis (AS) is characterised by insidious onset lower back pain. Poor symptom recognition results in delays in diagnosis of up to 11 years. Despite the widespread use of anti-tumour necrosis factor alpha (anti-TNFα) therapy, work disability remains a challenging problem in AS. METHODS:A retr...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-013-1054-3
更新日期：2014-12-01 00:00:00
abstract：BACKGROUND:Cadmium (Cd) is an environmental and industrial pollutant that induces a broad spectrum of toxicological effects, influences a variety of human organs, and is associated with poor semen quality and male infertility. Increasing evidence demonstrates that Cd induces testicular germ cell apoptosis in rodent ani...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-017-1595-y
更新日期：2017-11-01 00:00:00
abstract：BACKGROUND:Of over 20 different scoring systems to evaluate outcome following calcaneal fracture, the Maryland Foot Score has broad current acceptance. A general health survey, the Short Form 36 (SF 36) has also been used. AIMS:The study compared two scoring systems for assessing the outcome of open reduction and inte...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03166916
更新日期：2000-04-01 00:00:00
abstract：BACKGROUND:This article is a follow-up to an audit performed by the Department of Surgery and published in the Irish Journal of Medical Science in 1996. This audit reviewed all cases of Infantile Hypertrophic Pyloric Stenosis (IHPS) operated on over 22 years up to 1991. AIMS:We aim to demonstrate that radiologic inves...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/BF03169126
更新日期：2005-04-01 00:00:00
abstract：:Hepatic haemangiosarcoma is a rare condition although there are known carcinogens in 25%. This case reports hepatic haemangiosarcoma in a 59 year old man with psoriasis and Crohn's disease who had previously received combined treatment with psoralen and UVA light. ...
journal_title：Irish journal of medical science
pub_type： 杂志文章,评审
doi：10.1007/BF02942382
更新日期：1992-12-01 00:00:00
abstract：BACKGROUND:The presence of nodal metastases is the single most important prognostic factor in penile cancer. However, reliable assessment of nodal status in clinically node-negative (cN0) patients poses a challenge. Approximately 20% of these patients harbour occult nodal metastases. Currently available non-invasive ra...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-017-1558-3
更新日期：2017-11-01 00:00:00
abstract：OBJECTIVE:Evaluate condylar, ramal, and condylar plus ramal vertical mandibular asymmetry in patients with unilateral posterior crossbite (UPCB) and in patients with unilateral cleft lip and palate (UCLP) compared with subjects having normal occlusion. DESIGN:This cross-sectional study evaluated panoramic radiographs ...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-013-1020-0
更新日期：2014-09-01 00:00:00
abstract：BACKGROUND:'Slaintecare' aims to address complex patient care needs in an integrated fashion with an emphasis on patient-centred, patient-empowered community care.Currently there is a lack of knowledge of the impact of rare disease management in primary care and of the information tools required by general practitioner...
journal_title：Irish journal of medical science
pub_type： 杂志文章
doi：10.1007/s11845-019-02168-4
更新日期：2020-08-01 00:00:00
