Abstract:
:Fibroblast growth factors (FGFs) are known to be synthesized in the central nervous system (CNS) and to act on CNS cells in vitro, but less is known about their synthesis, expression, and role in vivo. In this work, using specific anti-acidic fibroblast growth factor (aFGF) antibodies, we have shown for the first time, by immunohistochemistry, that aFGF is expressed in spinal cord cells of young adult normal mice. This expression is predominant in the cell nucleus. Using immunohistochemical double staining procedures, we identified the cell type expressing aFGF as neurons, astrocytes, and oligodendrocytes, but for each type, cells were not all positively immunostained.
journal_name
J Neurosci Resjournal_title
Journal of neuroscience researchauthors
Tourbah A,Oliver L,Jeanny JC,Gumpel Mdoi
10.1002/jnr.490290417subject
Has Abstractpub_date
1991-08-01 00:00:00pages
560-8issue
4eissn
0360-4012issn
1097-4547journal_volume
29pub_type
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journal_title:Journal of neuroscience research
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