Microwave hyperthermia treatment increases heat shock proteins in human skeletal muscle.

Abstract:

OBJECTIVE:To test the hypothesis that microwave hyperthermia treatment (MHT) increases heat shock proteins (HSPs) in the human vastus lateralis muscle. METHODS:Four untrained healthy male volunteers participated in this study. The lateral side of the thigh of one leg (heated leg) was heated with a microwave generator (2.5 GHz, 150 W) for 20 min. At 1 day after the MHT, a muscle sample was taken from the heated leg. A control sample was taken from the unheated leg on another day of the MHT. For both legs, HSP90, HSP72 and HSP27 levels were compared. RESULTS:The HSP90, HSP72 and HSP27 levels in heated legs were significantly higher than those in control legs (p<0.05). CONCLUSIONS:Application of MHT can increase the levels of several HSPs in human skeletal muscle.

journal_name

Br J Sports Med

authors

Ogura Y,Naito H,Tsurukawa T,Ichinoseki-Sekine N,Saga N,Sugiura T,Katamoto S

doi

10.1136/bjsm.2006.032938

subject

Has Abstract

pub_date

2007-07-01 00:00:00

pages

453-5; discussion 455

issue

7

eissn

0306-3674

issn

1473-0480

pii

bjsm.2006.032938

journal_volume

41

pub_type

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