Abstract：
:For many years, operative dentistry has been using regenerative approaches to treat dental disease. The use of calcium hydroxide to stimulate reparative or reactionary dentin is clearly an example of such a therapeutic strategy. The advent of tissue engineering is allowing dentistry to move forward in the use of regeneration as an underlying principle for the treatment of dental disease. Tissue engineering is a multi-disciplinary science that brings together biology, engineering and clinical sciences with developing new tissues and organs. It is based on fundamental principles that involve the identification of appropriate cells, the development of conducive scaffolds and an understanding of the morphogenic signals required to induce cells to regenerate the tissues that were lost. This review is focused on the presentation and discussion of existing literature that covers the engineering of enamel, dentin and pulp, as well on the engineering of entire teeth. There are clearly major road-blocks to overcome before such strategies move to the clinic and are used regularly to treat patients. However, existing evidence strongly suggests that the engineering of new dental structures to replace tissues lost during the process of caries or trauma will have a place in the future of operative dentistry.
journal_name
Oper Dentjournal_title
Operative dentistryauthors
Nör JEdoi
10.2341/06-000subject
Has Abstractpub_date
2006-11-01 00:00:00pages
633-42issue
6eissn
0361-7734issn
1559-2863journal_volume
31pub_type
杂志文章,评审abstract：OBJECTIVE:The purpose of this study was to evaluate the effect of phosphoric acid pre-etching times on shear bond strength (SBS) and surface free energy (SFE) with single-step self-etch adhesives. METHODS:The three single-step self-etch adhesives used were: 1) Scotchbond Universal Adhesive (3M ESPE), 2) Clearfil tri-S...
journal_title：Operative dentistry
pub_type： 杂志文章
doi：10.2341/15-221-L
更新日期：2016-07-01 00:00:00
abstract：:The current study investigated the influence of carbamide peroxide on the flexural strength of tooth-colored restorative materials at two environmental temperatures. Seven restorative materials were used, including four resin composites (Filtek Z350, Filtek Z250, Synergy Flow and Filtek P60), a polyacid-modified compo...
journal_title：Operative dentistry
pub_type： 杂志文章
doi：10.2341/09-139-L
更新日期：2010-05-01 00:00:00
abstract：:This study evaluated the cytotoxicity of four single component dentin bonding agents: Syntac Single Component, Prime & Bond 2.1, Single Bond and One Up Bond F. The test materials were applied on dentin discs of dentin barrier models in the same way as in the clinical procedures recommended by each manufacturer. Cell v...
journal_title：Operative dentistry
pub_type： 杂志文章
doi：
更新日期：2003-07-01 00:00:00
abstract：:Of the many factors under their control, clinicians can manipulate light-exposure duration but must deal with a set intensity of light emitted from the dental curing unit. This research investigates the interdependence of exposure duration and source intensity on resin cure at various depths within a simulated light-c...
journal_title：Operative dentistry
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：:This study evaluated the regional tensile bond strength of a dual-cure resin composite core material to root canal dentin using photo and dual-cure adhesives and different modes of polymerization. Nineteen extracted premolars were decoronated and their root canals prepared to a depth of 8 mm and a width of 1.4 mm usin...
journal_title：Operative dentistry
pub_type： 杂志文章
doi：
更新日期：2003-09-01 00:00:00
abstract：:Hard tissue modification by means of laser irradiation is becoming popular in dentistry, since it promotes assorted responses between the tooth and the restorative material. Some studies on the bond strength of adhesive systems to Nd:YAG irradiated teeth have shown distinctive behaviors when irradiation was applied be...
journal_title：Operative dentistry
pub_type： 杂志文章
doi：10.2341/05-110
更新日期：2006-09-01 00:00:00
abstract：OBJECTIVES:To evaluate the effect of application protocol in resin-enamel microshear bond strength (μSBS), in situ degree of conversion, and etching pattern of three universal adhesive systems. METHODS AND MATERIALS:Sixty-three extracted third molars were sectioned in four parts (buccal, lingual, and proximals) and di...
journal_title：Operative dentistry
pub_type： 杂志文章
doi：10.2341/15-213-L
更新日期：2016-09-01 00:00:00
abstract：:This in vitro study evaluated the interfacial integrity of Class II resin composite restorations. The influence of a flowable composite and additional enamel etching was also evaluated. Deep, saucer-shaped Class II cavities were prepared in the mesial and distal proximal surfaces of 25 extracted human molars and assig...
journal_title：Operative dentistry
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2001-01-01 00:00:00
abstract：:The steady increase in online health information seeking by patients is ingrained in central notions of patient-centered care and shared decision-making models reflected in operative dentistry and the healthcare industry at large. More patients today seek health information prior to an appointment, communicate their f...
journal_title：Operative dentistry
pub_type： 杂志文章
doi：10.2341/14-312-LIT
更新日期：2015-09-01 00:00:00
abstract：:This case report illustrates how to restore severely compromised teeth with direct composite restorations. The size of the restorations presented is often considered by dentists as being a contraindication for direct composites. Hence, the technique is explained step by step, addressing the crucial points. ...
journal_title：Operative dentistry
pub_type： 杂志文章
doi：10.2341/15-001-T
更新日期：2016-09-01 00:00:00
abstract：OBJECTIVE:The purpose of this study was to evaluate the effects of different desensitizing agents on the prevention of root caries when applied to root surfaces. MATERIALS AND METHODS:Thirty human roots were sectioned into quarters with a 3 × 4 mm window. A desensitizer (VX, Clinpro™ XT Varnish; SP, Seal & Protect®; o...
journal_title：Operative dentistry
pub_type： 杂志文章
doi：10.2341/11-007-L
更新日期：2012-05-01 00:00:00
abstract：:The molar proximal half-crown cast gold restoration may be an ideal choice for the conservative treatment of teeth with only one compromised proximal aspect. ...
journal_title：Operative dentistry
pub_type： 杂志文章
doi：10.2341/10-T1
更新日期：2010-03-01 00:00:00
abstract：:The effect of microabrasion on human enamel has been well documented; however, no information is available on its effect on dentin or restorative materials. The purpose of this study was to evaluate the effect of the microabrasion technique on the surface roughness of restorative materials and enamel and dentin surfac...
journal_title：Operative dentistry
pub_type： 杂志文章
doi：
更新日期：1996-03-01 00:00:00
abstract：:Excessive etching of the dentin may decrease bond strength because the adhesive may fail to completely infiltrate to the base of the over-etched demineralized collagen network. The purpose of the present study was to evaluate the influence of increasing etching times on the microtensile bond strength of Single Bond an...
journal_title：Operative dentistry
pub_type： 杂志文章
doi：
更新日期：1999-05-01 00:00:00
abstract：:This study determined the influence of light curing protocols and matrix type on the margin quality and marginal seal of Class II resin-based composite restorations. In extracted human molars, box-shaped MOD cavities with 1 mm wide interproximal bevels were prepared with cervical margins located at least 1 mm coronal ...
journal_title：Operative dentistry
pub_type： 杂志文章
doi：10.2341/04-194
更新日期：2006-01-01 00:00:00
abstract：:The effect of interdental separation of a special separation ring and wooden wedge was investigated. In a split-mouth design, 27 patients were randomly assigned to one of two groups (W or S). In 11 patients, an interdental wooden wedge (Hawe-Neos) was placed (group W), and in 16 patients, a separation ring (Composi-Ti...
journal_title：Operative dentistry
pub_type： 杂志文章,随机对照试验
doi：10.2341/06-73
更新日期：2007-05-01 00:00:00
abstract：:This study examined the relationship between the bond agent application duration and the dentin bond strength of several single-application bonding systems. The restorative material/ bonding systems used were Reactmer, with its single-application bonding system Reactmer Bond (RB, Shofu Inc, Kyoto, Japan); Palfique Est...
journal_title：Operative dentistry
pub_type： 杂志文章
doi：
更新日期：2002-05-01 00:00:00
abstract：:This article outlines an atraumatic isolation approach and a conservative instrumentation sequence, followed by use of a highly viscous, rapid-setting, capsulated glass ionomer cement to manage a difficult deep proximal-cervical Class V lesion. ...
journal_title：Operative dentistry
pub_type： 杂志文章
doi：
更新日期：2004-05-01 00:00:00
abstract：:The DIAGNOdent, a device used in caries detection, uses a laser to excite fluorescence from pigments in carious tooth structure. In clinical use assessing occlusal surfaces, distance and tooth structure may separate the instrument's tip from the fluorescent source.The aim of this in vitro study was to examine the effe...
journal_title：Operative dentistry
pub_type： 杂志文章
doi：10.2341/10-179-L
更新日期：2012-03-01 00:00:00
abstract：:The aim of this study was to compare five all-in-one bonding agents with respect to microleakage, microtensile bond strength (μTBS), degree of conversion (DC) and the impact of cavity configuration. The materials tested were Adper Easy Bond, Clearfil S3 Bond, iBond, Optibond All-in-One, Xeno IV, and Adper Single Bond ...
journal_title：Operative dentistry
pub_type： 杂志文章
doi：10.2341/14-185-LR1
更新日期：2015-09-01 00:00:00
abstract：:This study evaluated the two-year clinical performance of two minimally invasive cavity preparation techniques, bur and laser, in Class I occlusal resin composite restorations. Twenty-seven patients, each having at least one pair of occlusal caries, were enrolled in this study. For each patient, one of the cavities wa...
journal_title：Operative dentistry
pub_type： 杂志文章
doi：10.2341/09-339-C
更新日期：2010-09-01 00:00:00
abstract：PURPOSE:To investigate the effect of different light-curing units and depths on the degree of conversion (DC) through Fourier transform infrared spectroscopy (FTIR) and Knoop Hardness Number (KHN) of a silorane-based composite resin (Filtek LS, 3M ESPE, St Paul, MN, USA) (LS). MATERIALS AND METHODS:LS specimens mounte...
journal_title：Operative dentistry
pub_type： 杂志文章
doi：10.2341/12-479
更新日期：2014-05-01 00:00:00
abstract：OBJECTIVES:To evaluate the effect of different surface treatments on the bond strength to a composite and a polymer-infiltrated ceramic CAD/CAM block after six-month artificial aging. METHODS AND MATERIALS:Two types of CAD/CAM blocks (Cerasmart, GC; Enamic, Vita Zahnfabrik) were cut in slabs of 4-mm thickness, divided...
journal_title：Operative dentistry
pub_type： 杂志文章
doi：10.2341/15-263-L
更新日期：2017-01-01 00:00:00
abstract：:The purpose of this double-blind clinical trial was to compare the retention rate in noncarious Class V lesions of two resin-based composite restorative materials with contrasting stiffness. Isolation with retraction cord, pressed paper triangles, and cotton rolls was used to closely mimic the procedures generally use...
journal_title：Operative dentistry
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：2000-01-01 00:00:00
abstract：OBJECTIVES:It has been reported that bleaching generates an increase in the activity of osteoclasts in vitro. We quantified the RANK-L and IL-1β biomarkers in a double-blind, randomized clinical trial evaluating the in vivo effect of hydrogen peroxide (35%) and peroxide carbamide (37%) six months after whitening. METH...
journal_title：Operative dentistry
pub_type： 杂志文章,随机对照试验
doi：10.2341/18-023-C
更新日期：2019-11-01 00:00:00
abstract：:A technique of restoring Class II posterior restorations with resin-based composite and a pre-polymerized composite insert was presented. This technique is intended to aid the practitioner in obtaining tight, broad, proximal contacts without having to purchase special instruments or materials. This method is not time-...
journal_title：Operative dentistry
pub_type： 杂志文章
doi：
更新日期：2004-07-01 00:00:00
abstract：:This study evaluated the effects of acid etching of the enamel and the combination of different light sources (halogen light, light-emitting diodes [LEDs], and LED/Laser) and the bleaching product on color change, penetration of hydrogen peroxide (H2O2), and cytotoxicity over time. The color change (ΔE) and the amount...
journal_title：Operative dentistry
pub_type： 杂志文章
doi：10.2341/14-364-L
更新日期：2016-01-01 00:00:00
abstract：:This study compared the viscoelastic properties of restorative and flowable bulk-fill resin-based composites (RBCs) with their conventional counterparts and evaluated the impact of aqueous solutions on viscoelastic properties. The materials examined included three conventional RBCs (Filtek Z350, Tetric N Ceram, and Be...
journal_title：Operative dentistry
pub_type： 杂志文章
doi：10.2341/19-005-L
更新日期：2020-03-01 00:00:00
abstract：:This in vitro study evaluated microleakage in Class II cavities restored with dental composite and varying light-curing units and the temperature of the composite when subjected to a thermocycling test. Ninety cavities were prepared on the proximal surfaces of bovine teeth and randomly divided according to the light-c...
journal_title：Operative dentistry
pub_type： 杂志文章
doi：10.2341/10-226-LR1
更新日期：2011-01-01 00:00:00
abstract：:This study compared microleakage of composite bonded to etched flattened enamel in seven groups of five extracted maxillary molars. The facial enamel of the molars was ground flat and etched for 20 seconds with 37% phosphoric acid gel. In one group, etching gel was not rinsed but dried only. In four groups, gel was ri...
journal_title：Operative dentistry
pub_type： 杂志文章
doi：
更新日期：1993-01-01 00:00:00
