当前位置： SCI文献检索 > ATHEROSCLEROSIS期刊下所有文献 > Serum tissue inhibitor of metalloproteinases-1 and higher risk features of coronary plaque: a volumetric multivessel intravascular ultrasound study.

Serum tissue inhibitor of metalloproteinases-1 and higher risk features of coronary plaque: a volumetric multivessel intravascular ultrasound study.

Abstract：

AIMS:The purpose of this study was to determine the relationship between higher-risk features of coronary plaque and serum levels of matrix metalloproteinase (MMP) family enzymes in the stable angina patients. METHODS AND RESULTS:In 36 patients, 75 coronary lesions were assessed by intravascular ultrasound. For each of the plaques remodelling index, mean calcium arc and plaque burden were measured. Positive remodelling and the values of the calcium arc and plaque burden above the respective medians were regarded as the higher-risk features and summarised for each lesion. Serum levels of MMP-2, -3, -7, -9, and tissue inhibitor of MMP (TIMP)-1 and -2 were measured in all patients. TIMP-1 level was the independent predictor of presence of a lesion with positive remodelling (OR 1.032; 95% CI: 1.004-1.061) and of a lesion with higher plaque burden (OR 1.026; 95% CI: 1.003-1.049) in a given patient. Whereas, MMP-2 level was an independent predictor of presence of a lesion with higher calcium arc (OR 1.035; 95% CI: 1.001-1.071). TIMP-1 level (p=0.003) was also an independent predictor of a number of higher-risk features in the highest-risk plaque in a given patient. CONCLUSIONS:TIMP-1 level correlates with clustering of plaque features associated with higher risk of complications in stable angina patients.

journal_name

Atherosclerosis

journal_title

Atherosclerosis

authors

Kruk M,Kalińczuk L,Pregowski J,Przyłuski J,Janas J,Chmielak Z,Demkow M,Debski A,Ciszewski A,Otto B,Witkowski A,Ruzyłło W

doi

10.1016/j.atherosclerosis.2006.08.045

subject

Has Abstract

pub_date

2007-10-01 00:00:00

pages

e57-63

issue

2

eissn

0021-9150

issn

1879-1484

pii

S0021-9150(06)00531-4

journal_volume

194

pub_type

杂志文章

相关文献

ATHEROSCLEROSIS文献大全
  • Peritoneal macrophages are distinct from monocytes and adherent macrophages.

    abstract：OBJECTIVE:Peritoneal macrophages are used in many studies related to atherosclerosis. In situ, they are non-adherent and upon culturing, they adhere and function as scavengers of modified lipoproteins and dead apoptotic cells. They also produce growth factors, suggesting that they may provide life-supporting function a...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2011.09.014

    authors： Selvarajan K,Moldovan L,Chandrakala AN,Litvinov D,Parthasarathy S

    更新日期：2011-12-01 00:00:00

  • Effect of endothelium on beta-VLDL metabolism by cultured smooth muscle cells of differing phenotype.

    abstract：:The effect of endothelial cells (EC) on the binding and internalisation of beta-very low density lipoprotein (beta-VLDL) and the subsequent accumulation of lipid was investigated in cultured smooth muscle cells (SMC) of different phenotype. The following combinations were examined: (i) SMC cultured and incubated with ...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/0021-9150(88)90302-4

    authors： Horrigan S,Campbell JH,Campbell GR

    更新日期：1988-05-01 00:00:00

  • Hypocholesterolemic effects of cholestyramine and colestipol in patients with familial defective apolipoprotein B-100.

    abstract：:Familial defective apolipoprotein B-100 (FDB) is a dominantly inherited disorder associated with hypercholesterolemia, in which substitution of the amino acid glutamine for arginine at position 3500 in the apoprotein B molecule results in LDL particles which bind poorly to the LDL receptor. To date, patients with FDB ...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/0021-9150(93)90130-m

    authors： Schmidt EB,Illingworth DR,Bacon S,Mahley RW,Weisgraber KH

    更新日期：1993-01-25 00:00:00

  • Relation between epicardial fat thickness and coronary flow reserve in women with chest pain and angiographically normal coronary arteries.

    abstract：OBJECTIVE:A significant proportion of women with angina-like chest pain and angiographically normal coronary arteries have microvascular dysfunction as detected by reduced coronary blood flow reserve (CFR). Classical clinical risk factors of atherosclerosis poorly predict this scenario. We sought to assess whether incr...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2008.09.038

    authors： Sade LE,Eroglu S,Bozbaş H,Ozbiçer S,Hayran M,Haberal A,Müderrisoğlu H

    更新日期：2009-06-01 00:00:00

  • Distribution of intimal smooth muscle cell masses and their relationship to early atherosclerosis in the abdominal aortas of young swine.

    abstract：:In the abdominal aortas of young mash-fed swine, intimal cell masses (pads, cushions) are located predominantly away from blood vessel orifices. They are found scattered throughout the aorta but nevertheless have a definite pattern of distribution. In the distal one half of the abdominal aorta, they are more frequent ...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/s0021-9150(79)80007-6

    authors： Scott RF,Thomas WA,Lee WM,Reiner JM,Florentin RA

    更新日期：1979-11-01 00:00:00

  • Apolipoprotein E polymorphism and atherosclerosis: association of the epsilon4 allele with defects in the internal elastic lamina.

    abstract：:The defects in the internal elastic lamina (IEL) have been proposed to be important for the migration of smooth muscle cells into the intima during atherosclerosis. We investigated the association of a genetic factor--apolipoprotein E (apoE) genotype--with the number of gaps in the IEL of the artery wall in 123 consec...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/s0021-9150(00)00388-9

    authors： Ilveskoski E,Järvinen O,Sisto T,Karhunen PJ,Laippala P,Lehtimäki T

    更新日期：2000-11-01 00:00:00

  • Nonalcoholic fatty liver disease and advanced fibrosis are associated with left ventricular diastolic dysfunction.

    abstract：BACKGROUND AND AIMS:Nonalcoholic fatty liver disease (NAFLD) may be associated with a wide spectrum of cardiac abnormalities, which share many metabolic risk factors. This study aimed to evaluate whether NAFLD is associated with left ventricular (LV) diastolic dysfunction independent of other classical risk factors. M...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2018.03.027

    authors： Chung GE,Lee JH,Lee H,Kim MK,Yim JY,Choi SY,Kim YJ,Yoon JH,Kim D

    更新日期：2018-05-01 00:00:00

  • Endothelium-dependent vasodilation, insulin resistance and the metabolic syndrome in an elderly cohort: the Prospective Investigation of the Vasculature in Uppsala Seniors (PIVUS) study.

    abstract：BACKGROUND:Only a few previous studies have investigated endothelium-dependent vasodilation in the metabolic syndrome (MetS). In the Prospective Study of the Vasculature in Uppsala Seniors (PIVUS) study, different techniques to assess vasodilation in conduit and resistance arteries were evaluated in relation to the Met...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2007.01.014

    authors： Lind L

    更新日期：2008-02-01 00:00:00

  • Inability of plasma high-density lipoproteins to inhibit cell adhesion molecule expression in human coronary artery endothelial cells.

    abstract：:High-density lipoproteins (HDL) have several antiatherogenic actions, including the ability to sequester cellular cholesterol, to protect low-density lipoproteins from oxidation and to inhibit platelet aggregation. An early event in atherogenesis is the adhesion and recruitment of blood monocytes, a process mediated b...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/s0021-9150(00)00444-5

    authors： Stannard AK,Khan S,Graham A,Owen JS,Allen SP

    更新日期：2001-01-01 00:00:00

  • Soluble intercellular adhesion molecule-1 and interleukin-6 levels reflect endothelial dysfunction in patients with primary hypercholesterolaemia treated with atorvastatin.

    abstract：:Adhesion molecules and cytokines are involved in the pathogenesis of intimal injury in atherosclerosis but their relationship with endothelial function remains unclear. The objectives of this study were to examine the effects of atorvastatin on soluble adhesion molecules, interleukin-6 (IL-6) and brachial artery endot...

    journal_title：Atherosclerosis

    pub_type： 临床试验,杂志文章

    doi：10.1016/s0021-9150(03)00193-x

    authors： Nawawi H,Osman NS,Annuar R,Khalid BA,Yusoff K

    更新日期：2003-08-01 00:00:00

  • Total cholesterol and stroke mortality in middle-aged and elderly adults: A prospective cohort study.

    abstract：BACKGROUND AND AIMS:The association between cholesterol and stroke has been inconsistent. This study aimed to examine the association between total cholesterol (TC) and mortality from total stroke and stroke subtypes. METHODS:503,340 Korean adults aged 40-80 years without a history of heart disease or stroke participa...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2017.12.003

    authors： Yi SW,Shin DH,Kim H,Yi JJ,Ohrr H

    更新日期：2018-03-01 00:00:00

  • Detection of atherosclerotic cardiovascular disease influences the perceived need for aggressive lipid management.

    abstract：BACKGROUND AND AIMS:Overt atherosclerotic cardiovascular disease (ASCVD) warrants aggressive lipid lowering. Imaging for ambiguous symptoms suggesting ischemia or for clarification of CV risk in asymptomatic individuals often uncovers previously unknown ASCVD. Guidelines do not provide clear recommendations for aggress...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2017.06.006

    authors： Mancini GBJ,Gupta M,Tsigoulis M,Cannon CP,Genest J,Ray KK,Santos RD,Watts GF,Raggi P

    更新日期：2017-08-01 00:00:00

  • Alcohol consumption and its relation to lipid-based cardiovascular risk factors among middle-aged women: the role of HDL(3) cholesterol.

    abstract：:To study the association of alcohol consumption and lipid-based cardiovascular risk factors among middle-age women, cross-sectional analysis among 274 middle-aged healthy women with different drinking habits and a follow-up analysis of alcoholic women during abstinence was performed. Serum total cholesterol, low and h...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/s0021-9150(00)00369-5

    authors： Sillanaukee P,Koivula T,Jokela H,Pitkäjärvi T,Seppä K

    更新日期：2000-10-01 00:00:00

  • Plasma proprotein convertase subtilisin-kexin type 9 does not change during 24h insulin infusion in healthy subjects and type 2 diabetic patients.

    abstract：PURPOSE:Proprotein convertase subtilisin-kexin type 9 (PCSK9) promotes low density lipoprotein (LDL) receptor degradation, thereby providing a key pathway for LDL metabolism. PCSK9 mRNA expression may be upregulated by insulin in murine models. Here we examined effects of exogenous hyperinsulinemia on plasma PCSK9 leve...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2010.10.028

    authors： Kappelle PJ,Lambert G,Dullaart RP

    更新日期：2011-02-01 00:00:00

  • The clinical importance of serum γ-glutamyltransferase level as an early predictor of obesity development in Korean men.

    abstract：BACKGROUND AND OBJECTIVE:Serum γ-glutamyl transferase (GGT) levels are known to be positively associated with obesity. We aimed at verifying an association between baseline GGT levels and the development of obesity in Korean men. PATIENTS AND METHODS:This prospective cohort study was performed on 18,510 initially non-...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2013.01.029

    authors： Suh YJ,Park SK,Choi JM,Ryoo JH

    更新日期：2013-04-01 00:00:00

  • The inherent accuracy of 1H NMR spectroscopy to quantify plasma lipoproteins is subclass dependent.

    abstract：:Proton NMR spectroscopy as a means to quantify lipoprotein subclasses has received wide clinical interest. The experimental part is a fast routine procedure that contrasts favourably to other lipoprotein measurement protocols. The difficulties in using (1)H NMR, however, are in uncovering the subclass specific informa...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2006.04.020

    authors： Ala-Korpela M,Lankinen N,Salminen A,Suna T,Soininen P,Laatikainen R,Ingman P,Jauhiainen M,Taskinen MR,Héberger K,Kaski K

    更新日期：2007-02-01 00:00:00

  • The effect of acute exercise on high density lipoprotein-cholesterol and the subfractions in females.

    abstract：:The effect of an acute exercise session on high density lipoprotein-cholesterol (HDL-C) and the subfractions HDL2-C and HDL3-C was determined for 9 healthy females (VO2max = 46.62 +/- 4.82 ml X kg-1 min-1). Each subject underwent a continuous 40-min run on a treadmill at a workload corresponding to 70% of VO2max. A ve...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/0021-9150(87)90120-1

    authors： Swank AM,Robertson RJ,Deitrich RW,Bates M

    更新日期：1987-02-01 00:00:00

  • Imatinib treatment attenuates growth and inflammation of angiotensin II induced abdominal aortic aneurysm.

    abstract：BACKGROUND:Abdominal aortic aneurysm (AAA) is characterized by vascular remodeling with increased infiltration of inflammatory cells and apoptosis/modulation of vascular smooth muscle cells (SMCs). Imatinib is a selective inhibitor of several tyrosine kinases, including PDGF receptors, Abl, and c-kit. The objective of ...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2016.04.006

    authors： Vorkapic E,Dugic E,Vikingsson S,Roy J,Mäyränpää MI,Eriksson P,Wågsäter D

    更新日期：2016-06-01 00:00:00

  • Reproducibility and biological variability of HDL's vascular functional assays.

    abstract：BACKGROUND:Recent failures of clinical trials promoting HDL-elevating therapies have prompted research groups to focus on its functional activity in disease. Endothelial effects of HDL can be measured with in vitro cell assays. The reproducibility and biological relevance of these assays have not been explored both in ...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2015.06.005

    authors： O'Neill F,McLoughlin E,Riwanto M,Manz J,Adler A,Sutill E,Khan T,Haywood R,Kay CW,D'Aiuto F,Charakida M,Landmesser U,Deanfield J

    更新日期：2015-08-01 00:00:00

  • LDL concentration is correlated with the removal from the plasma of a chylomicron-like emulsion in subjects with coronary artery disease.

    abstract：:In animal model studies, the uptake of chylomicron remnants after entering in the space of Disse occurs mainly by low-density lipoprotein (LDL) receptor and LDL receptor-related protein (LRP). In subjects, the relative importance of each one of these receptors for the clearance of chylomicron remnants is not fully und...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/s0021-9150(01)00661-x

    authors： Sposito AC,Santos RD,Hueb W,Ventura LI,Vinagre CC,Ramires JA,Maranhão RC

    更新日期：2002-04-01 00:00:00

  • Fetal aortic cholesterol concentration and metabolism: relationship to plasma cholesterol and potential role of placental factors.

    abstract：:The relationship of fetal plasma cholesterol levels to aortic free and esterified cholesterol concentration was determined in the rabbit during gestation. Plasma cholesterol levels (mg/dl) in early fetuses were markedly high and decreased at term. While aortic free cholesterol content increased with fetal age, cholest...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/0021-9150(89)90096-8

    authors： Cayatte AJ,Subbiah MT

    更新日期：1989-04-01 00:00:00

  • Fatigability and functional performance among older adults with low-normal ankle-brachial index: Cross-sectional findings from the Baltimore Longitudinal Study of Aging.

    abstract：BACKGROUND AND AIMS:Peripheral artery disease (PAD) is associated with poor mobility and fatigue, but the relationship between preclinical ankle-brachial index (ABI) and early markers of fatigue and functional decline has not been defined. METHODS:570 adults, 50 and older, from the Baltimore Longitudinal Study of Agin...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2018.03.037

    authors： Martinez-Amezcua P,Matsushita K,Simonsick EM,Ferrucci L,Schrack JA

    更新日期：2018-05-01 00:00:00

  • Blood pressure disturbances and endothelial dysfunction markers in children and adolescents with type 1 diabetes.

    abstract：OBJECTIVE:Being the earliest step on the way to atherosclerosis, endothelial dysfunction is particularly escalated in diabetes. This study aimed at assessing endothelial dysfunction and blood pressure disturbances in young patients with type 1 diabetes mellitus (T1DM) and defining their interrelations. METHODS:The stu...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2014.09.006

    authors： Machnica L,Deja G,Polanska J,Czupryniak L,Szymanska-Garbacz E,Loba J,Jarosz-Chobot P

    更新日期：2014-11-01 00:00:00

  • A brief review paper of the efficacy and safety of atorvastatin in early clinical trials.

    abstract：:Preclinical and clinical data on atorvastatin, a new 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, indicate that it has superior activity in treating a variety of dyslipidemic disorders characterized by elevations in low-density lipoprotein cholesterol (LDL-C) and/or triglycerides. Results for p...

    journal_title：Atherosclerosis

    pub_type： 杂志文章,评审

    doi：10.1016/s0021-9150(97)06066-8

    authors： Bakker-Arkema RG,Best J,Fayyad R,Heinonen TM,Marais AD,Nawrocki JW,Black DM

    更新日期：1997-05-01 00:00:00

  • Increased expression of C-reactive protein and tissue factor in acute coronary syndrome lesions: Correlation with serum C-reactive protein, angioscopic findings, and modification by statins.

    abstract：BACKGROUND:Serum C-reactive protein (CRP) is a strong risk predictor of cardiovascular events, and tissue factor (TF) plays a central role in thrombus formation of advanced atherosclerotic plaques. Aim of the present study was to quantify in situ CRP and TF in coronary atherectomy specimens associated with acute corona...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2008.03.028

    authors： Andrié RP,Bauriedel G,Braun P,Höpp HW,Nickenig G,Skowasch D

    更新日期：2009-01-01 00:00:00

  • Characterization of LncRNA expression profile and identification of novel LncRNA biomarkers to diagnose coronary artery disease.

    abstract：BACKGROUND AND AIMS:Dysregulation of long non-coding RNAs (lncRNAs) has been proven to be involved in the pathogenesis of coronary artery disease (CAD). However, it remains to be extensively explored. Thus, the present study aims to study expression patterns, biological functions, and diagnostic value of lncRNAs in CAD...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/j.atherosclerosis.2018.06.866

    authors： Li L,Wang L,Li H,Han X,Chen S,Yang B,Hu Z,Zhu H,Cai C,Chen J,Li X,Huang J,Gu D

    更新日期：2018-08-01 00:00:00

  • Fibrinogen, factor VII clotting activity and coronary artery disease severity.

    abstract：:To asses the relationship between fibrinogen, factor VII coagulant (VIIc) activity and extent of coronary artery disease, we studied 43 white males shown to have greater than 50% stenosis of at least one major coronary artery. Thirty six had a definite history of myocardial infarction at least 3 months earlier and wer...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/0021-9150(90)90108-u

    authors： Broadhurst P,Kelleher C,Hughes L,Imeson JD,Raftery EB

    更新日期：1990-12-01 00:00:00

  • Tissue lipoprotein lipase in the hyperthyroid rat. Effect of growth and aging.

    abstract：:The hydrolysis of lipoprotein triglycerides is catalyzed by lipoprotein lipase (LPL), an enzyme found in many tissues. We have examined tissue LPL activity (LPLA) in rats with experimentally-induced hyperthyroidism. In younger, lighter rats, hyperthyroidism was accompanied by a decrease in LPL in adipose tissue wherea...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/0021-9150(77)90088-0

    authors： Wilson DE,Jubiz W,Flowers CM,Carlile SI,Adolf AM

    更新日期：1977-03-01 00:00:00

  • Plasma lipid peroxidation in hyperlipidemic chickens.

    abstract：:Laying and genetically defective non-laying hens were evaluated for plasma lipid and plasma peroxidation levels. The non-layers developed extreme hyperlipidemia as well as greatly increased levels of lipid peroxidation. It was concluded that the concurrent presence of lipid peroxidation products must be considered whe...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/0021-9150(85)90143-1

    authors： Smith T,Toda T,Kummerow FA

    更新日期：1985-10-01 00:00:00

  • Recombinant proapoA-I(Lys107del) shows impaired lipid binding associated with reduced binding to plasma high density lipoprotein.

    abstract：:In the present study apoA-I (Lys 107del), a naturally occurring human apoA-I variant with a deletion of Lys 107, was expressed in E. coli to examine the effect of this mutation on lipid binding, cholesterol efflux and lecithin:cholesterol acyltranferase (LCAT) activation. Dimyristoyl phosphatidylcholine (DMPC) binding...

    journal_title：Atherosclerosis

    pub_type： 杂志文章

    doi：10.1016/s0021-9150(01)00496-8

    authors： Huang W,Matsunaga A,Li W,Han H,Hoang A,Kugi M,Koga T,Sviridov D,Fidge N,Sasaki J

    更新日期：2001-11-01 00:00:00