Mathematical simulation of dose-effect relationships for fish eggs exposed chronically to ionizing radiation.

Abstract:

:A mathematical model which simulates the observed dose-effect relationships for fish eggs exposed to chronic irradiation is presented. The model assumes that the exposed fish eggs may exist in one of the following states: normally developing, reversibly damaged, and lethally damaged. Reversible damages may be recovered by repairing mechanisms which are spent for the repairing processes. The model was applied to describe the observed differences in effects of chronic exposure for quickly (2 weeks) and slowly (up to 20 weeks) developing fish eggs. Calculations were performed for dose rates of chronic irradiation ranging from 10 to 300 mGy/day. Two types of radiation effects were considered-the effect on eggs survival (percentage of survived eggs at time t), and the depletion of the repairing pool (in percentage of its maximal value). The model predictions have been compared with the experimental data from the EPIC database. This comparison showed that the model adequately describes the radiation effects in fish eggs of different species, within a wide range of chronic radiation exposures.

journal_name

Radiat Environ Biophys

authors

Kryshev AI,Sazykina TG,Badalian KD

doi

10.1007/s00411-006-0058-z

subject

Has Abstract

pub_date

2006-09-01 00:00:00

pages

195-201

issue

3

eissn

0301-634X

issn

1432-2099

journal_volume

45

pub_type

杂志文章
  • Mortality from solid cancers other than lung, liver, and bone in relation to external dose among plutonium and non-plutonium workers in the Mayak Worker Cohort.

    abstract::Exposure to ionizing radiation has well-documented long-term effects on cancer rates and other health outcomes in humans. While in vitro experimental studies had demonstrated that the nature of some radiation effects depend on both total dose of the radiation and the dose rate (i.e., the pattern of dose distribution o...

    journal_title:Radiation and environmental biophysics

    pub_type: 杂志文章

    doi:10.1007/s00411-016-0670-5

    authors: Sokolnikov M,Preston D,Stram DO

    更新日期:2017-03-01 00:00:00

  • Late effects of local irradiation on the expression of inflammatory markers in the Arteria saphena of C57BL/6 wild-type and ApoE-knockout mice.

    abstract::Combined action of irradiation (IR), shear stress, and high blood pressure is well recognized to induce damage to vasculature, while data on pathological effects of IR in large peripheral vessels with low blood pressure are scarce. The purpose of the present study was hence to investigate time- and dose-dependent effe...

    journal_title:Radiation and environmental biophysics

    pub_type: 杂志文章

    doi:10.1007/s00411-013-0492-7

    authors: Patties I,Habelt B,Rosin B,Dörr W,Hildebrandt G,Glasow A

    更新日期:2014-03-01 00:00:00

  • Residual radiation effect in the murine hematopoietic stem cell compartment.

    abstract::Stem cells surviving radiation injury may carry defects which contribute to long-term effects. The ratio of 125-iododeoxyuridine (IUdR) uptake into spleens of lethally irradiated recipient mice between day 3 and day 5 after cell transfusion revealed reduced proliferative ability (PF) of spleen seeding cells in paralle...

    journal_title:Radiation and environmental biophysics

    pub_type: 杂志文章

    doi:10.1007/BF01211733

    authors: von Wangenheim KH,Peterson HP,Feinendegen LE

    更新日期:1986-01-01 00:00:00

  • NOREC, a Monte Carlo code for simulating electron tracks in liquid water.

    abstract::The work reported here was originally motivated by a discussion of Monte Carlo computer codes for electron transport in water given in Report No. 130 by the National Council on Radiation Protection and Measurements (NCRP). It was pointed out (correctly) that a published depth-dose distribution calculated by the Oak Ri...

    journal_title:Radiation and environmental biophysics

    pub_type: 杂志文章

    doi:10.1007/s00411-003-0201-z

    authors: Semenenko VA,Turner JE,Borak TB

    更新日期:2003-10-01 00:00:00

  • The effect of high energy electron irradiation on blood-brain barrier permeability to haloperidol and stobadin in rats.

    abstract::The heads of rats were irradiated by 4 MeV electrons in doses 90, 180, and 360 Gy. The observed times of deaths ranged 120-600, 60-420, and 150-370 min after 90, 180, and 360 Gy, respectively. A dose dependent decrease of the brain uptake index of haloperidol was observed 1 and 3 h post radiation. On the other hand an...

    journal_title:Radiation and environmental biophysics

    pub_type: 杂志文章

    doi:10.1007/BF01210512

    authors: Trnovec T,Volenec K,Bezek S,Kállay Z,Durisová M,Scasnár V,Kubu M,Svoboda V

    更新日期:1991-01-01 00:00:00

  • Analysis of chromosome aberrations in human peripheral lymphocytes induced by in vitro alpha-particle irradiation.

    abstract::Irradiation of human lymphocytes by alpha-particles under different conditions has been seen to be substantially more effective in the induction of dicentric chromosomes than irradiation by gamma-rays. However, the relative biological effectiveness (RBE) determined in these studies differed by a factor of more than 10...

    journal_title:Radiation and environmental biophysics

    pub_type: 杂志文章

    doi:10.1007/s004110050028

    authors: Schmid E,Hieber L,Heinzmann U,Roos H,Kellerer AM

    更新日期:1996-08-01 00:00:00

  • Cause-of-death registers in radiation-contaminated areas of the Russian Federation and Kazakhstan.

    abstract::Since the early 1990s, information on radiation-exposed populations other than those exposed from the Chernobyl accident in 1986 has become increasingly available for international scientific research. It is essential to understand how the cohorts of exposed populations have been defined and what mechanisms can be use...

    journal_title:Radiation and environmental biophysics

    pub_type: 杂志文章,评审

    doi:10.1007/s00411-001-0128-1

    authors: Winkelmann RA,Tretyakov FD,Startsev NV,Kolyado IB,Gusev BI,Grosche B,Storm HH,Hall P

    更新日期:2002-03-01 00:00:00

  • Radiation risks in perspective: radiation-induced cancer among cancer risks.

    abstract::The majority of the public in industrial countries believes that pollution and low doses of radiation are threats to good health. As a matter of fact, when these putative risks are compared to those originating from lifestyle, they appear very small. In particular, the risks associated with low doses of irradiation, e...

    journal_title:Radiation and environmental biophysics

    pub_type: 杂志文章,评审

    doi:10.1007/pl00007682

    authors: Tubiana M

    更新日期:2000-03-01 00:00:00

  • Subtraction of background damage in PFGE experiments on DNA fragment-size distributions.

    abstract::The non-random distribution of DNA breakage in pulsed-field gel electrophoresis (PFGE) experiments poses a problem of proper subtraction of the background damage to obtain a fragment-size distribution due to radiation only. As been pointed out by various authors, a naive bin-to-bin subtraction of the background signal...

    journal_title:Radiation and environmental biophysics

    pub_type: 杂志文章

    doi:10.1007/s00411-007-0098-z

    authors: Ponomarev AL,Belli M,Hahnfeldt PJ,Hlatky L,Sachs RK,Cucinotta FA

    更新日期:2007-06-01 00:00:00

  • The relationship between sensitivity to 60-Hz electric fields and induced transmembrane potentials in plants root cells.

    abstract::Growth rates and cell diameters were determined from 12 species of plant roots exposed to a 60-Hertz (Hz) electric field of 360 Volts per meter (V/m) in an aqueous inorganic nutrient medium [conductivity: 0.07-0.09 Siemens per meter (S/m)]. The degree of growth depression ranged from zero to nearly 100 percent of cont...

    journal_title:Radiation and environmental biophysics

    pub_type: 杂志文章

    doi:10.1007/BF01210937

    authors: Inoue M,Miller MW,Carstensen EL,Brayman AA

    更新日期:1985-01-01 00:00:00

  • Risk of second bone sarcoma following childhood cancer: role of radiation therapy treatment.

    abstract::Bone sarcoma as a second malignancy is rare but highly fatal. The present knowledge about radiation-absorbed organ dose-response is insufficient to predict the risks induced by radiation therapy techniques. The objective of the present study was to assess the treatment-induced risk for bone sarcoma following a childho...

    journal_title:Radiation and environmental biophysics

    pub_type: 杂志文章

    doi:10.1007/s00411-013-0510-9

    authors: Schwartz B,Benadjaoud MA,Cléro E,Haddy N,El-Fayech C,Guibout C,Teinturier C,Oberlin O,Veres C,Pacquement H,Munzer M,N'guyen TD,Bondiau PY,Berchery D,Laprie A,Hawkins M,Winter D,Lefkopoulos D,Chavaudra J,Rubino C,D

    更新日期:2014-05-01 00:00:00

  • Voxel-based computational models of real human anatomy: a review.

    abstract::Computational models of human anatomy are mathematical representations of human anatomy designed to be used in dosimetry calculations. They have been used in dosimetry calculations for radiography, radiotherapy, nuclear medicine, radiation protection and to investigate the effects of low frequency electromagnetic fiel...

    journal_title:Radiation and environmental biophysics

    pub_type: 杂志文章,评审

    doi:10.1007/s00411-003-0221-8

    authors: Caon M

    更新日期:2004-02-01 00:00:00

  • Effects of mixed neutron-gamma irradiation in vivo on the cell surfaces of murine blood cells.

    abstract::For studies on cell membranes, mice were exposed to mixed neutron + gamma reactor-radiation in the range of total doses from 0.5 to 4.5 Gy. Changes in functional activity of plasma membranes of erythrocytes, platelets, and lymphocytes were followed by a lectin-binding technique at various intervals afterwards. The amo...

    journal_title:Radiation and environmental biophysics

    pub_type: 杂志文章

    doi:10.1007/BF01407598

    authors: Kubasova T,Antal S,Somosy Z,Köteles GJ

    更新日期:1984-01-01 00:00:00

  • Photoproducts generated from hematoporphyrin under high-intensity picosecond flash photolysis. Evidences for involvement of biophotonic processes.

    abstract::Hematoporphyrin (Hp) solutions were subjected to a wide range high intensity (0.2-10.0 GW/cm2) near-UV laser pulse radiation (lambda exc = 355 nm, pulse duration 30 ps). The formation of stable Hp photoproducts was followed by UV-VIS absorption spectroscopy and liquid-gel column chromatography. As judged by the influe...

    journal_title:Radiation and environmental biophysics

    pub_type: 杂志文章

    doi:10.1007/BF01210525

    authors: Gantchev T,Keskinova E,Kaltchev M,Angelov D

    更新日期:1990-01-01 00:00:00

  • A comparative kinetic study on the conversion of fluoresceindiacetate to fluorescein in living cells and in vitro.

    abstract::The kinetics of fluoresceindiacetate (FDA)-hydrolysis in erythrocytes, CHO-cells and homogenized cells was investigated by means of fluorescence spectroscopy. At a 10(-6)m FDA concentration the enzymatic conversion in the homogenized cells can be described by first order reactions. When studying intact cells, total ki...

    journal_title:Radiation and environmental biophysics

    pub_type: 杂志文章

    doi:10.1007/BF01331024

    authors: Sontag W

    更新日期:1977-04-27 00:00:00

  • Microirradiation of cells with energetic heavy ions.

    abstract::The ion microprobe SNAKE at the Munich 14 MV tandem accelerator achieves beam focussing by a superconducting quadrupole doublet and can make use of a broad range of ions and ion energies, from 20 MeV protons to 200 MeV gold ions. Because of these properties, SNAKE is particularly attractive for biological microbeam ex...

    journal_title:Radiation and environmental biophysics

    pub_type: 杂志文章

    doi:10.1007/s00411-003-0222-7

    authors: Hauptner A,Dietzel S,Drexler GA,Reichart P,Krücken R,Cremer T,Friedl AA,Dollinger G

    更新日期:2004-02-01 00:00:00

  • Radio-biologically motivated modeling of radiation risks of mortality from ischemic heart diseases in the Canadian fluoroscopy cohort study.

    abstract::Recent analyses of the Canadian fluoroscopy cohort study reported significantly increased radiation risks of mortality from ischemic heart diseases (IHD) with a linear dose-response adjusted for dose fractionation. This cohort includes 63,707 tuberculosis patients from Canada who were exposed to low-to-moderate dose f...

    journal_title:Radiation and environmental biophysics

    pub_type: 杂志文章

    doi:10.1007/s00411-019-00819-9

    authors: Schöllnberger H,Kaiser JC,Eidemüller M,Zablotska LB

    更新日期:2020-03-01 00:00:00

  • Stem cell kinetics in spleen and bone marrow after single and fractionated irradiation of infant mice.

    abstract::The number and type of stem cells in spleen and bone marrow of mice were determined after exposure to a single dose of 150 R on day 6, to a single dose of 500 R on day 6 or day 9 or to a fractionated dose of 150 R + 350 R on day 6 and 9. The stem cells were assayed on the basis of colony forming units (CFU) in spleen ...

    journal_title:Radiation and environmental biophysics

    pub_type: 杂志文章

    doi:10.1007/BF01324267

    authors: Gerber GB,Maes J

    更新日期:1980-01-01 00:00:00

  • Distribution of radiation induced lesions in human chromosomes and dose-effect relation analysed with G-banding.

    abstract::Human female lymphocytes were exposed to X-rays in vitro at 7 different doses between 40-280 R. In 830 metaphases chromosome analyses were carried out with either conventional staining or G-banding, respectively. 486 breakpoints are non-randomly distributed between chromosomes and chromosome arms. An excess of lesions...

    journal_title:Radiation and environmental biophysics

    pub_type: 杂志文章

    doi:10.1007/BF01340573

    authors: Bauchinger M,Götz G

    更新日期:1979-01-01 00:00:00

  • Calculation on spectrum of direct DNA damage induced by low-energy electrons including dissociative electron attachment.

    abstract::In this work, direct DNA damage induced by low-energy electrons (sub-keV) is simulated using a Monte Carlo method. The characteristics of the present simulation are to consider the new mechanism of DNA damage due to dissociative electron attachment (DEA) and to allow determining damage to specific bases (i.e., adenine...

    journal_title:Radiation and environmental biophysics

    pub_type: 杂志文章

    doi:10.1007/s00411-016-0681-2

    authors: Liu W,Tan Z,Zhang L,Champion C

    更新日期:2017-03-01 00:00:00

  • Irradiated stem cells and ageing of the haematopoietic system.

    abstract::In the work presented here, changes in haematopoiesis of mice (B6129SF2/J) were studied 1 year after their whole-body exposure to a dose of 7 Gy (72% of mice survived). The irradiated mice were compared with non-irradiated younger (4 months of age) and older (16 months of age) mice. There was a significant increase in...

    journal_title:Radiation and environmental biophysics

    pub_type: 杂志文章

    doi:10.1007/s00411-012-0401-5

    authors: Vávrová J,Sinkorová Z,Rezáčová M,Tichý A,Filip S,Mokrý J,Lukášová E

    更新日期:2012-05-01 00:00:00

  • Reconstruction of the contamination of the Techa River in 1949-1951 as a result of releases from the "Mayak" Production Association.

    abstract::More accurate reconstruction of the radioactive contamination of the Techa River system in 1949-1951 has been made on the basis of refined data on the amounts and the rate of discharge of radionuclides into the Techa River from the Mayak Production Association; this has led to the development of a modified Techa River...

    journal_title:Radiation and environmental biophysics

    pub_type: 历史文章,杂志文章

    doi:10.1007/s00411-012-0414-0

    authors: Shagina NB,Vorobiova MI,Degteva MO,Peremyslova LM,Shishkina EA,Anspaugh LR,Napier BA

    更新日期:2012-11-01 00:00:00

  • Impact of the Great East Japan Earthquake on feeding methods and newborn growth at 1 month postpartum: results from the Fukushima Health Management Survey.

    abstract::This study examined the effects of three disasters (the Great East Japan Earthquake of March 11, 2011, followed by a tsunami and the Fukushima Daiichi Nuclear Power Plant accident) on feeding methods and growth in infants born after the disasters. Using results from the Fukushima Health Management Survey, Soso Distric...

    journal_title:Radiation and environmental biophysics

    pub_type: 杂志文章

    doi:10.1007/s00411-016-0636-7

    authors: Kyozuka H,Yasuda S,Kawamura M,Nomura Y,Fujimori K,Goto A,Yasumura S,Abe M

    更新日期:2016-05-01 00:00:00

  • Nuclear energy: health impact of carbon-14.

    abstract::Estimates are presented on the carbon-14 generation rates in several reactor types and in peaceful nuclear explosions. If the carbon-14 generated in light water reactors is released, the population radiation dose rate it causes initially will be comparable to that resulting from the krypton-85 and tritium generated in...

    journal_title:Radiation and environmental biophysics

    pub_type: 杂志文章

    doi:10.1007/BF01331176

    authors: Pohl RO

    更新日期:1976-12-23 00:00:00

  • The contribution of soil adhesion to radiocaesium uptake by leafy vegetables.

    abstract::The Goiânia accident, Brazil, was used as an opportunity to quantify the contributions of different mechanisms, in particular mass loading, leading to caesium uptake by leafy vegetables in a semi-urban environment contaminated with 137Cs. Soil splash contributions of 70-90% were quantified for lettuce and 50-60% for g...

    journal_title:Radiation and environmental biophysics

    pub_type: 杂志文章

    doi:10.1007/BF01210458

    authors: Amaral EC,Paretzke HG,Campos MJ,Pires do Rio MA,Franklin M

    更新日期:1994-01-01 00:00:00

  • Effect of thiol reagents and ionizing radiation on the permeability of erythrocyte membrane for spin-labeled non-electrolytes.

    abstract::Four different thiol reagents: p-chloromercuribenzoic acid (pCMB), mercuric chloride (HgCl2), N-ethylmaleimide (NEM), and 5,5'-dithiobis-(2-nitrobenzoic acid) (DTNB) were employed as agents modifying the transport of a hydrophilic and hydrophobic non-electrolyte spin labels: 4-hydroxy-2,2,6,6-tetramethylpiperidine-1-o...

    journal_title:Radiation and environmental biophysics

    pub_type: 杂志文章

    doi:10.1007/BF01323760

    authors: Gwoździński K,Bartosz G,Leyko W

    更新日期:1983-01-01 00:00:00

  • TEL1 from Saccharomyces cerevisiae suppresses chromosome aberrations induced by ionizing radiation in ataxia-telangiectasia cells without affecting cell cycle checkpoints.

    abstract::The TEL1 gene from Saccharomyces cerevisiae has been shown to be the closest sequence homologue to ATM, the gene mutated in ataxia-telangiectasia (A-T) patients. Functional homology shared between the ATM and Tell proteins has recently been demonstrated based on heterologous expression of the TEL1 gene in human cells ...

    journal_title:Radiation and environmental biophysics

    pub_type: 杂志文章

    doi:10.1007/s00411-001-0125-4

    authors: Cao JP,Meyn MS,Eckardt-Schupp F,Fritz E

    更新日期:2001-12-01 00:00:00

  • Laser flash photolysis study on antioxidant properties of hydroxycinnamic acid derivatives.

    abstract::The antioxidant properties of hydroxycinnamic acid derivatives (HCA) were studied by laser flash photolysis. The transient species with maximum absorption at 360 nm were assigned to the phenoxyl radical of HCA. The SO (4) (.-) induced oxidation of HCA was also investigated. It was shown that the interaction of SO (4) ...

    journal_title:Radiation and environmental biophysics

    pub_type: 杂志文章

    doi:10.1007/s00411-006-0041-8

    authors: Zhu H,Zhao H,Zhang Z,Wang W,Yao S

    更新日期:2006-05-01 00:00:00

  • Simplified Bayesian method: application in cytogenetic biological dosimetry of mixed n + γ radiation fields.

    abstract::This article describes the application of a simplified Bayesian method for estimation of doses from a mixed field using cytogenetic biological dosimetry, taking as an example neutron and gamma radiation emitted from the MARIA nuclear research reactor in Poland. The Bayesian approach is a good alternative to the common...

    journal_title:Radiation and environmental biophysics

    pub_type: 杂志文章

    doi:10.1007/s00411-018-0764-3

    authors: Słonecka I,Łukasik K,Fornalski KW

    更新日期:2019-03-01 00:00:00

  • Modelling of the temporal indoor radon variation in Bulgaria.

    abstract::In this study, temporal variations of indoor radon concentrations in Bulgaria were investigated. The radon concentrations were measured by nuclear track detectors as part of the Bulgarian National Survey, performed in the dwellings of 28 regional districts. The detectors were exposed through a year in two consecutive ...

    journal_title:Radiation and environmental biophysics

    pub_type: 杂志文章

    doi:10.1007/s00411-019-00789-y

    authors: Ivanova K,Stojanovska Z

    更新日期:2019-08-01 00:00:00