Abstract:
BACKGROUND:The use of whole-cell pertussis vaccine has led to a significant decline in incidence of the disease among children. This change in the epidemiological profile led to an increased number of cases among teenagers and adults, as a result of loss of immunity to the disease or vaccine after approximately 10 years. An increased number of cases was also observed among non-immunized or partially immunized infants. Licensure of the DTP vaccine against diphtheria, tetanus, and acellular pertussis formulated specifically for patients over 10 years of age (Tdap) suggests the possibility of controlling pertussis in the most affected age groups over the past few years. SOURCES OF DATA:Data were collected from MEDLINE. The research was limited to the period between January 1995 and January 2006. SUMMARY OF THE FINDINGS:In some countries there are two Tdap vaccines licensed for patients over 10 years of age. One of them contains five immunogenic components of Bordetella pertussis (pertussis toxin, filamentous hemagglutinin, fimbriae 2 and 3, and pertactin), and the other contains three components (pertactin, filamentous hemagglutinin, and inactivated pertussis toxin), the latter being the only one licensed in Brazil up to now. Although the composition of the two vaccines differs, studies show that they have similar effectiveness and immunogenicity. Some authors, however, emphasize that it is difficult to make a precise assessment of the immunological response to the vaccine and its duration. Several countries currently recommend the use of Tdap vaccine for adolescents. Canada has extended the target population up to 54 years of age. The guideline is that this group should receive one dose of the vaccine to reinforce the basic immunization scheme. This is based on study results that show that the vaccine-induced immunity lasts for around 6 to 12 years. Assessments of the economic impact of routine use of the vaccine in adolescents showed a positive cost-benefit ratio. Results of the epidemiological impact depend on the quality of diagnosis so that data reflect the reality of the disease. CONCLUSIONS:Although some questions remain to be clarified, the literature indicates the possibility of solving the "reappearance" of whooping cough (pertussis) with the use of Tdap vaccine. Perhaps the strategy of using a second booster dose in adolescence to replace the double diphtheria and tetanus vaccine should be adopted immediately.
journal_name
J Pediatr (Rio J)journal_title
Jornal de pediatriaauthors
de Carvalho AP,Pereira EMdoi
10.2223/JPED.1491subject
Has Abstractpub_date
2006-07-01 00:00:00pages
S15-24issue
3 Suppleissn
0021-7557issn
1678-4782journal_volume
82pub_type
杂志文章,评审abstract:OBJECTIVE:To assess the carotid intima-media thickness and factors associated with cardiovascular disease in children and adolescents with chronic kidney disease. MATERIAL AND METHODS:Observational, cross-sectional study carried out at the Universidade Federal de São Paulo (chronic kidney disease outpatient clinics) w...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.1016/j.jped.2018.06.010
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:To present an updated review of the most common upper respiratory infections (URI) in children seen by the pediatrician in outpatient clinics, for better diagnostic and therapeutic decisions. SOURCES:References from Medline database were reviewed. The most relevant articles were selected. SUMMARY OF THE FIN...
journal_title:Jornal de pediatria
pub_type: 杂志文章,评审
doi:10.2223/jped.1002
更新日期:2003-05-01 00:00:00
abstract:OBJECTIVE:This article presents a review of the main aspects related to lung transplant in children and shows the experience of the first medical team to perform this procedure in Latin America. SOURCES:Literature review of scientific articles, using the MEDLINE and Lilacs databases. SUMMARY OF THE FINDINGS:The artic...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:
更新日期:2002-11-01 00:00:00
abstract::OBJECTIVE: This study aimed to determine the prevalence of recurrent episodes of pneumonia in patients referred to the pulmonology outpatient unit at "Serviço de Pneumologia Pediatrica" of the Instituto de Puericultura e Pediatria Martagão Gesteira/UFRJ and to review the recurrent concept in accordance to medical refe...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/jped.32
更新日期:2000-01-01 00:00:00
abstract:OBJECTIVE:The main concepts involved in the therapeutic management of intracranial hypertension are revisited, including pathophysiology, monitoring, the traditional approach, and also the presentation of recently proposed therapies. SOURCE OF DATA:The main medical literature data bases (especially Medline and Lilacs)...
journal_title:Jornal de pediatria
pub_type: 杂志文章,评审
doi:10.2223/jped.1090
更新日期:2003-11-01 00:00:00
abstract:OBJECTIVE:To investigate the association between postpartum depression and the occurrence of exclusive breastfeeding. METHOD:This is a cross-sectional study conducted in the states of the Northeast region, during the vaccination campaign in 2010. The sample consisted of 2583 mother-child pairs, with children aged from...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.1016/j.jped.2016.08.005
更新日期:2017-01-01 00:00:00
abstract::OBJECTIVE: To present and discuss the indications, the endoscopic and histologic findings and the complications of upper digestive endoscopies carried out in children and adolescents.METHODS: We have done 228 endoscopies in pediatric patients with ages between 3 months to 19 years (x=5.7 y) during a period of 8 months...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/jped.410
更新日期:1998-01-01 00:00:00
abstract::OBJECTIVE: Review the theoretical bases on the maintenance of the acid-basic balance, the pathophysiology of the disturbances and its therapeutics in the child.METHODS: References were obtained from computerized searches on the National Library of Medicine (Medline), recent review articles and personal files.RESULTS: ...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/jped.393
更新日期:1999-11-01 00:00:00
abstract::OBJECTIVES: To identify rubella prevalence in different ages and population groups and rubella susceptibility of pregnant and postpartum women according to age, number of children and spontaneous abortion. METHODS: Cross-sectional study of sero-survey type. Children and students were selected in day-care centers and s...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/jped.470
更新日期:1998-11-01 00:00:00
abstract:OBJECTIVE:To review the most important aspects of the clinical presentation and treatment of children with cancer in intensive care units. SOURCE OF DATA:Medline (1970 to 2003); search terms: children, cancer, oncology, intensive care, complications. General and pediatric oncology textbooks. SUMMARY OF THE FINDINGS:P...
journal_title:Jornal de pediatria
pub_type: 杂志文章,评审
doi:10.2223/jped.1100
更新日期:2003-11-01 00:00:00
abstract:OBJECTIVE:To review the main causes of new bronchopulmonary dysplasia and the strategies utilized to decrease its incidence in extremely low birth weight infants. SOURCES OF DATA:For this review a MEDLINE search from 1966 to October 2004, the Cochrane Database, abstracts from the Society for Pediatric Research and rec...
journal_title:Jornal de pediatria
pub_type: 杂志文章,评审
doi:10.2223/1304
更新日期:2005-03-01 00:00:00
abstract:OBJECTIVE:to evaluate changes in the biochemical profile of children treated or being treated for moderate or severe stunting in a nutrition recovery and education center. METHODS:this was a retrospective longitudinal study of 263 children treated at this center between August of 2008 to August of 2011, aged 1 to 6 ye...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.1016/j.jped.2013.12.007
更新日期:2014-07-01 00:00:00
abstract:OBJECTIVE:To analyze the implementation of a protocol proposed by the Brazilian National Health Surveillance Agency (Agência Nacional de Vigilância Sanitária - ANVISA) to improve sepsis diagnosis in very low birth weight newborns. METHODS:This was a prospective study that evaluated the implementation of a protocol inv...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.1016/j.jped.2013.01.009
更新日期:2013-09-01 00:00:00
abstract:OBJECTIVE:To describe the characteristics of macrophage activation syndrome associated with juvenile idiopathic arthritis. DESCRIPTION:This is a retrospective study involving 462 patients with juvenile idiopathic arthritis. Seven (1.5%) of those patients suffered from systemic onset juvenile idiopathic arthritis and d...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:
更新日期:2004-11-01 00:00:00
abstract:OBJECTIVE:To meta-analyze health-related quality of life in pediatric patients with chronic kidney disease in comparison to healthy patients according to the dimensions of the PedsQL instrument. SOURCES OF DATA:A systematic review was performed with meta-analysis for the mean difference in each of the health-related q...
journal_title:Jornal de pediatria
pub_type: 杂志文章,评审
doi:10.1016/j.jped.2020.10.013
更新日期:2020-12-17 00:00:00
abstract::OBJECTIVES: To describe the characteristics of the patients not resuscitated in a university affiliated pediatric hospital. To characterize the data registered in the chart regarding the resuscitation and evaluate ethical and legal aspects of CPR (cardiopulmonary resuscitation). METHODS: Retrospective study of 176 dea...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/jped.89
更新日期:2000-11-01 00:00:00
abstract::OBJECTIVE: Evaluation of epidemiological, clinical and laboratory features of Plasmodium vivax malaria in children and adolescents. METHODS: This study was carried out in the Malaria Program of the Evandro Chagas Institute (Belém, Pará), from January 1995 to November 1996. 100 children and adolescents with the diagnos...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/jped.295
更新日期:1999-05-01 00:00:00
abstract::OBJECTIVE: To study plasma levels of IL-1beta and IL-6 in order to distinguish the presence of bacterial infection in newborn infants with fever. METHODS: A cohort of 117 newborn infants with postnatal age equal to or less than 5 days, with no previous use of antibiotic therapy, and with clinical suspicion of bacteria...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/jped.253
更新日期:1999-01-01 00:00:00
abstract::OBJECTIVE: Growth curves can be used to assess intrauterine growth, to predict diseases in newborns, and to characterize different populations. The objective of this study was to obtain intrauterine growth curves of newborns from the maternity ward of the Hospital Albert Einstein (MAE) and compare them with intrauteri...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/jped.202
更新日期:2001-05-01 00:00:00
abstract:OBJECTIVE:Report the incidence, epidemiology, clinical features, death, and vaccination status of patients with whooping cough and perform genotypic characterization of isolates of B. pertussis identified in the state of Paraná, during January 2007 to December 2013. METHODS:Cross-sectional study including 1,209 patien...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.1016/j.jped.2014.09.004
更新日期:2015-07-01 00:00:00
abstract:OBJECTIVE:Duchenne muscular dystrophy, an X-linked genetic disease, leads to progressive muscle weakness mainly in the lower limbs. Motor function tests help to monitor disease progression. Can low-cost, simple assessments help in the diagnostic suspicion of Duchenne muscular dystrophy? The authors aim to define the se...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.1016/j.jped.2019.02.003
更新日期:2020-01-01 00:00:00
abstract::Immediate skin test reactions are the hallmark of atopic diseases. EMLA (eutectic mixture of local anesthetics) is a local anesthetic that reduces the pain and apprehension for skin testing. We studied EMLA effects on the skin prick test with allergen and histamine. Reactions were evaluated by means of wheal and flare...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/jped.613
更新日期:1996-07-01 00:00:00
abstract::In order to better understand the natural history of chronic functional constipation, a questionnaire was applied to 163 children and infants, before beginning standardized treatment. Median age (range) at start was 3 mo(0-108 mo) but age at arrival at the Pediatric Gastroenterology Unit was 53 mo(2-146 mo). In 62.4% ...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/jped.688
更新日期:1994-09-01 00:00:00
abstract:OBJECTIVE:To review well-known aspects of exogenous surfactant therapy, and to discuss controversial points regarding the current state of research. SOURCES:Review of the literature, using Medline and Cochrane Database Library, in association with the authors' experience in relation to exogenous surfactant replacement...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:10.2223/jped.900
更新日期:2002-11-01 00:00:00
abstract:OBJECTIVE:To report a case of an infant with endstage renal failure caused by primary hyperoxaluria. METHODS:The review of the literature showed the rarity of the disease. In France, the prevalence is about 1.05/million and the incidence rate is 0.12/million/year. A survey, performed in international specialized cente...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:
更新日期:2002-03-01 00:00:00
abstract:OBJECTIVES:To identify the prevalence of iron deficiency in the population studied, as well as verifying if such deprivation is associated with vitamin A deficiency. METHODS:One hundred seventy-nine children, > or = 24 months and < 72 months of age, with no diarrhea and/or fever at collection were studied. Vitamin A d...
journal_title:Jornal de pediatria
pub_type: 杂志文章
doi:
更新日期:2005-03-01 00:00:00
abstract:OBJECTIVE:To assess the incidence of brain death (BD) and its medical management and adopted protocols after its diagnosis in seven pediatric intensive care units (PICUs) located in three Brazilian regions. METHODS:A cross-sectional and multicenter study was conducted, based on the retrospective review of medical reco...
journal_title:Jornal de pediatria
pub_type: 杂志文章,多中心研究
doi:10.2223/JPED.1594
更新日期:2007-03-01 00:00:00
abstract::The purpose of the authors in this article was to evaluate the effects of supplementing maternal milk with two different caloric formulas on the growth of premature newborns until they reached 40 weeks of post-conceptional age. Seventy premature infants weighing < 1750g at birth were randomized: 35 adequate for gestat...
journal_title:Jornal de pediatria
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.2223/jped.607
更新日期:1996-05-01 00:00:00
abstract:OBJECTIVE:To present an up-to-date and critical review regarding food allergies, focusing mainly on treatment and prevention. SOURCES:Review of published literature searched on MEDLINE database; those data which were the most up-to-date and representative were selected (2000-2006). The search included the European Soc...
journal_title:Jornal de pediatria
pub_type: 杂志文章,评审
doi:10.2223/JPED.1587
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:To contribute with information about the adequate administration of drugs during breastfeeding. SOURCES OF DATA:MEDLINE articles from 1993 to 2004, and Lilacs articles from 1995 to 2004 were selected in Portuguese, Spanish and English, by including the following keywords: breastfeeding, lactation, drugs and ...
journal_title:Jornal de pediatria
pub_type: 杂志文章,评审
doi:10.2223/1246
更新日期:2004-11-01 00:00:00