Abstract：
:Oral verrucous carcinoma (OVC) is a rare variant of squamous cell carcinoma with a characteristic morphology and specific behavior. To date, few studies are available focusing the prevalence and clinicopathologic features of the oral verrucous carcinoma in Brazilian population. A total of 3,500 primary oral well-differentiated squamous cell carcinoma surgically excised in the A.C. Camargo Cancer Hospital and Amaral Carvalho Cancer Hospital, Brazil, from 1980 to 2000 were retrospectively reviewed. Twenty cases of verrucous carcinomas were identified, most of them occurring in older male with age above the sixth decade, the sites frequently affected being the lower lip and the hard palate. Microscopically, the tumor showed a heavily keratinized lesion with compressive invasion pattern, little atypia, and free surgical margins. The local recurrence was verified in 38.5% of the patients with oral verrucous carcinoma; however, regional recurrence and distant metastasis were not verified. The results suggest that, although it is less frequent and with excellent prognosis, the verrucous carcinoma presents a potential for local recurrence that should be considered during the surgical planning of this neoplasm in the oral cavity.
journal_name
Clin Oral Investigjournal_title
Clinical oral investigationsauthors
Oliveira DT,de Moraes RV,Fiamengui Filho JF,Fanton Neto J,Landman G,Kowalski LPdoi
10.1007/s00784-006-0050-7subject
Has Abstractpub_date
2006-09-01 00:00:00pages
205-9issue
3eissn
1432-6981issn
1436-3771journal_volume
10pub_type
杂志文章abstract：OBJECTIVES:A multicentric randomized, 3-year prospective study was conducted to determine for how long Biodentine, a new biocompatible dentine substitute, can remain as a posterior restoration. MATERIALS AND METHODS:First, Biodentine was compared to the composite Z100®, to evaluate whether and for how long it could be...
journal_title：Clinical oral investigations
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1007/s00784-012-0701-9
更新日期：2013-01-01 00:00:00
abstract：OBJECTIVES:Bony reconstruction of jaw defects using the free fibular flap and dental rehabilitation mostly requires insertion of dental implants within the transferred fibula bone. The aim of this paper was to discuss results of the implant stability with data on the possible benefit for the patient's quality of life a...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-015-1487-3
更新日期：2016-01-01 00:00:00
abstract：:Fluoride is used in dentistry as a prophylactic agent to reduce caries rates due to the demineralization/remineralization effect and its influence on the metabolism of cariogenic bacteria. The purpose of this study was to evaluate the cytotoxic effects of sodium fluoride (NaF) on three different cell lines and the ant...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-002-0157-4
更新日期：2002-06-01 00:00:00
abstract：:This paper presents a short review of three groups of tools which can be or are used for the tissue engineering of mineralized oral structures: growth factor delivery systems (GFDS) and surface bioactivation with covalent bound peptides or with nanomechanically linked proteins. According to the reported personal exper...
journal_title：Clinical oral investigations
pub_type： 杂志文章,评审
doi：10.1007/s007840050128
更新日期：2000-06-01 00:00:00
abstract：:A total of 110 patients with neurofibromatosis 1 (NF1) were evaluated for their dental health. Appropriate cohorts from national Finnish databases were used as reference. The results showed that NF1 patients presented lower rate of caries compared to controls in age groups under 35 years. The differences between NF1 p...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-009-0341-x
更新日期：2011-02-01 00:00:00
abstract：OBJECTIVES:We sought to identify oral symptoms found in hyperparathyroidism and compare their rate of occurrence, as well as potential variations in sequelae between primary, secondary, and tertiary hyperparathyroidism. MATERIALS AND METHODS:Database searches were performed through EMBASE and PubMed, with a continual ...
journal_title：Clinical oral investigations
pub_type： 杂志文章,评审
doi：10.1007/s00784-017-2124-0
更新日期：2018-01-01 00:00:00
abstract：OBJECTIVES:To evaluate and compare the obturation quality of mineral trioxide aggregate (MTA) and Biodentine placed with hand condensation or indirect ultrasonic activation technique in teeth models simulating perforating internal root resorption (IRR) using micro-computed tomographic (micro-CT) imaging. MATERIALS AND...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-018-2502-2
更新日期：2019-02-01 00:00:00
abstract：:This retrospective study investigated the frequency and time history of chipping or facings failure of three-unit and four-unit tooth-supported metal ceramic (MC) fixed partial prostheses (FPDs). Six hundred fifty-four MC FPDs were inserted according to a standardized treatment protocol at the Department of Prosthodon...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-011-0511-5
更新日期：2012-04-01 00:00:00
abstract：OBJECTIVE:Aggregatibacter actinomycetemcomitans, specially its highly leucotoxic strain (JP2 clone), represents an etiological factor for the onset and progression of aggressive types of periodontitis. The aims of this investigation were to investigate the most relevant periodontal pathogens in the subgingival microbio...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-015-1653-7
更新日期：2016-09-01 00:00:00
abstract：OBJECTIVES:The objective of this study was to evaluate the bond strength of three root-end filling materials (MTAA-MTA Angelus, MTAS-experimental MTA Sealer, and ZOE- zinc oxide and eugenol cement) in retrograde preparations performed with different ultrasonic tips (CVD, Trinity, and Satelec). MATERIALS AND METHOD:Nin...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-015-1708-9
更新日期：2016-11-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to evaluate the acidogenicity of dual-species biofilms of bifidobacteria and Streptococcus mutans. MATERIALS AND METHODS:The following strains were tested: Bifidobacterium dentium DSM20436, Parascardovia denticolens DSM10105, and Scardovia inopinata DSM10107. Streptococcus mutans UA...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-016-1958-1
更新日期：2017-06-01 00:00:00
abstract：OBJECTIVE:To evaluate the contamination level of toothbrushes by mutans streptococci (MS) and the efficacy of antimicrobial solutions: cetylpyridinium chloride 0.05 % (CPC; Cepacol™) and chlorhexidine 0.12 % (CHX; Periogard™), to disinfect toothbrushes of preschool-aged children in day-care centers. MATERIAL AND METHO...
journal_title：Clinical oral investigations
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00784-013-1169-y
更新日期：2014-11-01 00:00:00
abstract：OBJECTIVES:Recent scientific evidences suggest a relevant role of the oral cavity in the transmission and pathogenicity of SARS-CoV-2. METHODS:A literature search was performed in PubMed, up to April 30, 2020, focusing on SARS-CoV-2, COVID-19, oral cavity, and antimicrobial agents. RESULTS:Oral viral load of SARS-CoV...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-020-03413-2
更新日期：2020-08-01 00:00:00
abstract：OBJECTIVES:The main purpose of this study was to investigate the detailed healing process of the roots and surrounding periodontium [cementum, periodontal ligament (PDL), and bone] at different time points after intentional root damage with miniscrew implants (MSIs). MATERIALS AND METHODS:After cone-beam computed tomo...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-017-2194-z
更新日期：2018-03-01 00:00:00
abstract：OBJECTIVES:The aim of the study was to measure the percentage of volume of voids and gaps in the apical third of root canals obturated with two techniques using micro-computed tomography. MATERIALS AND METHODS:Fifty-four single-rooted teeth were collected and root canal-prepared. The roots were randomly allocated into...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-012-0875-1
更新日期：2013-11-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to investigate the chemokine expression profiles in gingival crevicular fluid (GCF) and serum in patients with advanced chronic periodontitis and to assess the impact of smoking on local and systemic levels of chemokines. MATERIALS AND METHODS:Thirty patients with chronic periodonti...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-014-1314-2
更新日期：2015-06-01 00:00:00
abstract：BACKGROUND:Few studies regarding the distribution of pediatric oral diseases are available. Thus, the aim of this study was to investigate the incidence and demographic profile of neoplasms and non-neoplastic lesions among children and adolescents (0-19 years old). METHODS:A retrospective descriptive cross-sectional s...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-018-2581-0
更新日期：2019-04-01 00:00:00
abstract：:The purpose of this study was to determine the risk of microbiological transmission into the dental laboratory via impressions and dental stone models. Metal master models were contaminated with Bacillus subtilis and Streptococcus sanguis. Impressions in alginate, polyvinylsiloxane, and polyether were used, and models...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-002-0174-3
更新日期：2002-09-01 00:00:00
abstract：OBJECTIVE:The present study aimed to identify and quantify the elution of monomers of five different resin-based CAD/CAM blocks (RCBs) using HPLC. METHODS:Five different RCBs were used in the study: GC Cerasmart (CS), Voco Grandio blocs (GR), 3M Lava Ultimate (LU), Shofu Block (SB), and Vita Enamic (VE). Fifteen sampl...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-020-03377-3
更新日期：2021-01-01 00:00:00
abstract：OBJECTIVES:The present longitudinal study aimed to compare changes in the lower third molar position and nerve involvement in orthodontically treated patients with and without premolar extractions. MATERIALS AND METHODS:The sample consisted of pretreatment and posttreatment panoramic radiographs of 349 orthodontically...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-013-1148-3
更新日期：2014-09-01 00:00:00
abstract：OBJECTIVES:Candida albicans is the most common fungal pathogen in humans, but other Candida species cause candidosis. Candida species display significant differences in their susceptibility to antimycotic drugs. Patients with symptomatic or erythematous oral lichen planus (OLP) commonly have Candida infection requiring...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-012-0757-6
更新日期：2013-04-01 00:00:00
abstract：OBJECTIVES:Determine the association between sialadenitis and osteonecrosis of the jaw (ONJ) in head and neck cancer (HNC) patients with varying severity of sialadenitis, treatment modalities, and cancer locations. MATERIALS AND METHODS:A total of 40,168 HNC patients, including 1907 ONJ subjects and 7559 matched compa...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-018-2465-3
更新日期：2019-02-01 00:00:00
abstract：OBJECTIVES:To assess the association between periodontal disease and Helicobacter pylori (H. pylori) infection in oral cavity. MATERIALS AND METHODS:We searched PubMed, Embase, Web of Science, Cochrane library, Gray literature, and clinicaltrials.gov for eligible studies up to September 25, 2019. Odds ratios (ORs) and...
journal_title：Clinical oral investigations
pub_type： 杂志文章,meta分析
doi：10.1007/s00784-020-03330-4
更新日期：2020-07-01 00:00:00
abstract：OBJECTIVES:Transglutaminase-2 (TGM-2) protein is involved in the cross-linking of matrix proteins resulting in several fibrotic disorders and can be induced by reactive oxygen species (ROS). Little is known about its role in the development of oral submucocal fibrosis (OSF). Hence, we hypothesize that TGM-2 may have a ...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-015-1579-0
更新日期：2016-06-01 00:00:00
abstract：OBJECTIVE:The aim of this work was to evaluate the anti-inflammatory and antiresorptive effects of Calendula officinalis (CLO) on alveolar bone loss (ABL) in rats. MATERIAL AND METHODS:Male Wistar rats were subjected to ABL by ligature with nylon thread around the second upper left molar. The contralateral hemimaxilla...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-017-2308-7
更新日期：2018-07-01 00:00:00
abstract：OBJECTIVES:We aimed at investigating whether the interaction between the local inflammation, periodontitis, and obesity is independently associated with systemic inflammation. METHODS:From the population-based Study of Health in Pomerania, 3366 participants, without (2366) and with (1000) obesity, were studied for the...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-020-03514-y
更新日期：2020-08-22 00:00:00
abstract：OBJECTIVES:The objective of this study was to evaluate the inhibition of demineralization around enamel-dentin/restoration interface after dentin pretreatment with 2.5% titanium tetrafluoride (TiF4). MATERIALS AND METHODS:Forty dental class V cavities at the cementoenamel junction were distributed into four groups (n ...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-015-1573-6
更新日期：2016-05-01 00:00:00
abstract：OBJECTIVE:Biomechanical orthodontics loading of the periodontium initiates a cascade of inflammatory signaling events that induce periodontal remodeling and finally facilitate orthodontic tooth movement. Pattern recognition receptors such as toll-like receptors (TLRs) have been well characterized for their ability to i...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-019-03111-8
更新日期：2020-04-01 00:00:00
abstract：OBJECTIVES:Detecting bacterial activity is considered a promising approach to monitor shifts from symbiosis to dysbiosis in oral microbiome. The present study aimed at investigating both the relative bacterial activity and the lactate dehydrogenase (ldh) gene expression of caries-associated bacteria in a site-specific ...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s00784-020-03691-w
更新日期：2020-11-23 00:00:00
abstract：:The present study examines the three-dimensional (3D) morphology of early approximal subsurface enamel caries lesions and subjacent dentin reactions in deciduous molars. Twenty-three extracted primary molars were embedded in Technovit 9100 and serial sections were cut using a saw microtome. Forty approximal lesions we...
journal_title：Clinical oral investigations
pub_type： 杂志文章
doi：10.1007/s007840050066
更新日期：1998-12-01 00:00:00
