当前位置： SCI文献检索 > NEUROSCIENCE期刊下所有文献 > Barosensory cells in the nucleus tractus solitarius receive convergent input from group III muscle afferents and central command.

Barosensory cells in the nucleus tractus solitarius receive convergent input from group III muscle afferents and central command.

Abstract：

:Some neural mechanism must prevent the full expression of the baroreceptor reflex during static exercise because arterial blood pressure increases even though the baroreceptors are functioning. Two likely candidates are central command and input from the thin fiber muscle afferents evoking the exercise pressor reflex. Recently, activation of the mesencephalic locomotor region, an anatomical locus for central command, was found to inhibit the discharge of nucleus tractus solitarius cells that were stimulated by arterial baroreceptors in decerebrated cats. In contrast, the effect of thin fiber muscle afferent input on the discharge of nucleus tractus solitarius cells stimulated by baroreceptors is not known. Consequently in decerebrated unanesthetized cats, we examined the responses of barosensory nucleus tractus solitarius cells to stimulation of thin fiber muscle afferents and to stimulation of the mesencephalic locomotor region, a maneuver which evoked fictive locomotion. We found that electrical stimulation of either the mesencephalic locomotor region or the gastrocnemius nerve at current intensities that recruited group III afferents inhibited the discharge of nucleus tractus solitarius cells receiving baroreceptor input. We also found that the inhibitory effects of both gastrocnemius nerve stimulation and mesencephalic locomotor region stimulation converged onto the same barosensory nucleus tractus solitarius cells. We conclude that the nucleus tractus solitarius is probably the site whereby input from both central command and thin fiber muscle afferents function to reset the baroreceptor reflex during exercise.

journal_name

Neuroscience

journal_title

Neuroscience

authors

Degtyarenko AM,Kaufman MP

doi

10.1016/j.neuroscience.2006.02.050

subject

Has Abstract

pub_date

2006-07-07 00:00:00

pages

1041-50

issue

3

eissn

0306-4522

issn

1873-7544

pii

S0306-4522(06)00303-4

journal_volume

140

pub_type

杂志文章

相关文献

NEUROSCIENCE文献大全
  • Chronic stress modulates neural and cardiovascular responses during reversal learning.

    abstract：:Animal studies have revealed that chronic stress shifts cognitive strategies from the flexible goal-directed action to the simple and rigid habit action. In addition, stress-induced atrophy in the prefrontal cortex and dorsomedial striatum which are involved in the goal-directed action and hypertrophy of the dorsolate...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2011.07.014

    authors： Ohira H,Matsunaga M,Kimura K,Murakami H,Osumi T,Isowa T,Fukuyama S,Shinoda J,Yamada J

    更新日期：2011-10-13 00:00:00

  • An autoradiographic analysis of ascending projections from the medullary reticular formation in the rat.

    abstract：:Ascending projections from the several nuclei of the medullary reticular formation were examined using the autoradiographic method. The majority of fibers labeled after injections of [3H]leucine into nucleus gigantocellularis ascended within Forel's tractus fasciculorum tegmenti which is located ventrolateral to the m...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(86)90305-2

    authors： Vertes RP,Martin GF,Waltzer R

    更新日期：1986-11-01 00:00:00

  • The mossy fiber projection of the nucleus reticularis tegmenti pontis to the flocculus and adjacent ventral paraflocculus in the cat.

    abstract：:The pontine projection of the flocculus and adjacent ventral paraflocculus was investigated with antegrade and retrograde axonal tracer techniques. Injections of horseradish peroxidase into the floccular complex revealed subsets of labeled neurons in the nucleus reticularis tegmenti pontis, the nucleus raphe pontis an...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(84)90049-6

    authors： Gerrits NM,Epema AH,Voogd J

    更新日期：1984-03-01 00:00:00

  • Pharmacological suppression of the median raphe nucleus with serotonin1A agonists, 8-OH-DPAT and buspirone, produces hippocampal theta rhythm in the rat.

    abstract：:The effects on the hippocampal electroencephalogram of microinjections of procaine hydrochloride and the serotonin1A agonists, 8-OH-DPAT and buspirone, into the median raphe nucleus were examined in the urethane anesthetized rat. Injections of procaine, 8-OH-DPAT or buspirone into the median raphe nucleus produced a c...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(94)90255-0

    authors： Vertes RP,Kinney GG,Kocsis B,Fortin WJ

    更新日期：1994-05-01 00:00:00

  • Adenosine receptors linked to adenylate cyclase activity in human neuroblastoma cells: modulation during cell differentiation.

    abstract：:In IMR32 neuroblastoma cells, the two adenosine receptor agonists N6-R-phenylisopropyladenosine and 5'-N-ethylcarboxamidoadenosine dose-dependently stimulated membrane adenylate cyclase activity with potencies consistent with the presence of adenosine receptors of the A2-subtype. The S enantiomer of N6-R-phenylisoprop...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(89)90173-5

    authors： Abbracchio MP,Cattabeni F,Clementi F,Sher E

    更新日期：1989-01-01 00:00:00

  • Identification of neural pathways involved in genital reflexes in the female: a combined anterograde and retrograde tracing study.

    abstract：:The medial preoptic area (MPOA) is important for reproductive behavior in females. However, the descending pathways mediating these responses to the spinal motor output are unknown. The MPOA does not directly innervate the spinal cord. Therefore, pathways mediating MPOA-induced changes in sexual behavior must relay in...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2004.04.063

    authors： Marson L,Foley KA

    更新日期：2004-01-01 00:00:00

  • Pharmacological properties of AC-3933, a novel benzodiazepine receptor partial inverse agonist.

    abstract：:We investigated in this study the pharmacological properties of AC-3933 (5-(3-methoxyphenyl)-3-(5-methyl-1,2,4-oxadiazol-3-yl)-1,6-naphthyridin-2(1H)-one), a novel benzodiazepine receptor (BzR) partial inverse agonist. AC-3933 potently inhibited [3H]-flumazenil binding to rat whole brain membrane with a Ki value of 5....

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2013.10.031

    authors： Hashimoto T,Kiyoshi T,Kohayakawa H,Iwamura Y,Yoshida N

    更新日期：2014-01-03 00:00:00

  • Expression of agrin in the developing and adult rat brain.

    abstract：:Agrin, a synaptic basal lamina protein, is essential for the formation of the vertebrate neuromuscular junction. Agrin's role in synaptogenesis in the central nervous system has, however, not been elucidated. Therefore, we performed immunohistochemical analysis of agrin localization in adult rat brain using agrin-spec...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/s0306-4522(96)00345-4

    authors： Cohen NA,Kaufmann WE,Worley PF,Rupp F

    更新日期：1997-01-01 00:00:00

  • Quantitation of neurokinin 1 receptor internalization and recycling in guinea-pig myenteric neurons.

    abstract：:Agonist-induced endocytosis and recycling of G protein-coupled receptors contributes to desensitization and resensitization of the receptors. In this study, we have used fluorescence immunohistochemistry, confocal microscopy and digital image analysis to quantify the proportion of receptor in the cytoplasm and on the ...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/s0306-4522(98)00176-6

    authors： Southwell BR,Seybold VS,Woodman HL,Jenkinson KM,Furness JB

    更新日期：1998-12-01 00:00:00

  • Ubiquitination and E3 Ubiquitin Ligases in Rare Neurological Diseases with Comorbid Epilepsy.

    abstract：:Ubiquitination is a post-translational modification that can dynamically alter the function, degradation and transport of a protein, as well as its interaction with other proteins, and activity of an enzyme. Dysfunctional ubiquitination is detrimental to normal cellular functions, and can result in severe diseases. Ov...

    journal_title：Neuroscience

    pub_type： 杂志文章,评审

    doi：10.1016/j.neuroscience.2019.12.030

    authors： Zhu J,Tsai NP

    更新日期：2020-01-21 00:00:00

  • Form of dual-specificity tyrosine-(Y)-phosphorylation-regulated kinase 1A nonphosphorylated at tyrosine 145 and 147 is enriched in the nuclei of astroglial cells, adult hippocampal progenitors, and some cholinergic axon terminals.

    abstract：:Compelling lines of evidence indicate that overexpression of dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A (DYRK1A) in subjects with trisomy 21 (Down syndrome[DS]) contributes to the abnormal structure and function of the DS brain. In the present study, we used a novel, phospho-dependent antibody r...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2011.08.028

    authors： Kida E,Walus M,Jarząbek K,Palminiello S,Albertini G,Rabe A,Hwang YW,Golabek AA

    更新日期：2011-11-10 00:00:00

  • Pre- and post-synaptic effects of manipulating surface charge with divalent cations at the photoreceptor synapse.

    abstract：:Persistence of horizontal cell (HC) light responses in extracellular solutions containing low Ca2+ plus divalent cations to block Ca2+ currents (ICa) has been attributed to Ca2+-independent neurotransmission. Using a retinal slice preparation to record both ICa and light responses, we demonstrate that persistence of H...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2004.08.043

    authors： Cadetti L,Thoreson WB,Piccolino M

    更新日期：2004-01-01 00:00:00

  • Drug therapies for attentional disorders alter the signal-to-noise ratio in the superior colliculus.

    abstract：:Despite high levels of use, the mechanism of action of effective pharmacotherapies in attention deficit hyperactivity disorder (ADHD) is unknown. It has recently been hypothesized that one site of therapeutic action is the midbrain superior colliculus, a structure traditionally associated with visual processing, but a...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2009.09.007

    authors： Dommett EJ,Overton PG,Greenfield SA

    更新日期：2009-12-15 00:00:00

  • Effects of estradiol on the stimulation of dopamine turnover in mesolimbic and nigrostriatal systems by cocaine- and amphetamine-regulated transcript peptide in female rats.

    abstract：:The present studies aimed to determine whether estradiol (E(2)) modulates the stimulation of cocaine- and amphetamine-regulated transcript (CART) peptide in the mesolimbic and nigrostriatal dopaminergic systems. I.c.v. administration of the CART peptide (55-102, 1 microg/3 microl) increased dopamine turnover (3,4-dihy...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2008.01.086

    authors： Shieh KR,Yang SC

    更新日期：2008-07-17 00:00:00

  • Evidence for beta corticomuscular coherence during human standing balance: Effects of stance width, vision, and support surface.

    abstract：:The role of the cerebral cortex in maintaining human standing balance remains unclear. Beta corticomuscular coherence (CMC) provides a measure of communication between the sensory-motor cortex and muscle, but past literature has not demonstrated significant beta CMC during human stance. This study evaluated the effect...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2015.04.009

    authors： Jacobs JV,Wu G,Kelly KM

    更新日期：2015-07-09 00:00:00

  • Mouse strains that lack spinal dynorphin upregulation after peripheral nerve injury do not develop neuropathic pain.

    abstract：:Several experimental models of peripheral neuropathy show that a significant upregulation of spinal dynorphin A and its precursor peptide, prodynorphin, is a common consequence of nerve injury. A genetically modified mouse strain lacking prodynorphin does not exhibit sustained neuropathic pain after nerve injury, supp...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2003.08.021

    authors： Gardell LR,Ibrahim M,Wang R,Wang Z,Ossipov MH,Malan TP Jr,Porreca F,Lai J

    更新日期：2004-01-01 00:00:00

  • Heme oxygenase-1, heme oxygenase-2 and biliverdin reductase in peripheral ganglia from rat, expression and plasticity.

    abstract：:The expression of inducible and constitutive heme oxygenase and biliverdin reductase was studied in normal and cultured peripheral ganglia from adult rats, using immunocytochemistry and in situ hybridization. Dramatic changes were induced by one to two days' culturing of dorsal root ganglia, nodose ganglia, otic gangl...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/s0306-4522(99)00466-2

    authors： Magnusson S,Ekström J,Elmér E,Kanje M,Ny L,Alm P

    更新日期：2000-01-01 00:00:00

  • Glycosaminoglycans boost insulin-like growth factor-I-promoted neuroprotection: blockade of motor neuron death in the wobbler mouse.

    abstract：:Wobbler mice display forelimb weakness, altered paw positioning, reduced running speed, muscle atrophy and motor neuron loss; co-treatment with glycosaminoglycans and insulin-like growth factor-I counteracts the progression of the disease. Reportedly, treatment with glycosaminoglycans or insulin-like growth factor-I s...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/s0306-4522(99)00095-0

    authors： Vergani L,Losa M,Lesma E,Di Giulio AM,Torsello A,Müller EE,Gorio A

    更新日期：1999-01-01 00:00:00

  • Molecular characterization and functional expression of a substance P receptor from the sympathetic ganglion of Rana catesbeiana.

    abstract：:Substance P is an important neuropeptide neurotransmitter in the central, autonomic and enteric nervous systems. In sympathetic ganglia, substance P is thought to play a role in modulating synaptic transmission. Release of substance P by neuronal stimulation or direct application of substance P to ganglionic neurons i...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/s0306-4522(97)00027-4

    authors： Simmons MA,Brodbeck RM,Karpitskiy VV,Schneider CR,Neff DP,Krause JE

    更新日期：1997-08-01 00:00:00

  • Repeated forced swim stress enhances CFA-evoked thermal hyperalgesia and affects the expressions of pCREB and c-Fos in the insular cortex.

    abstract：:Stress affects brain activity and promotes long-term changes in multiple neural systems. Exposure to stressors causes substantial effects on the perception and response to pain. In several animal models, chronic stress produces lasting hyperalgesia. The insular (IC) and anterior cingulate cortices (ACC) are the region...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2013.11.045

    authors： Imbe H,Kimura A,Donishi T,Kaneoke Y

    更新日期：2014-02-14 00:00:00

  • Whole transcriptome expression of trigeminal ganglia compared to dorsal root ganglia in Rattus Norvegicus.

    abstract：:The trigeminal ganglia (TG) subserving the head and the dorsal root ganglia (DRG) subserving the rest of the body are homologous handling sensory neurons. Differences exist, as a number of signaling substances cause headache but no pain in the rest of the body. To date, very few genes involved in this difference have ...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2017.03.027

    authors： Kogelman LJA,Christensen RE,Pedersen SH,Bertalan M,Hansen TF,Jansen-Olesen I,Olesen J

    更新日期：2017-05-14 00:00:00

  • Src controls neuronal migration by regulating the activity of FAK and cofilin.

    abstract：:Migration of postmitotic neurons in the developing cortex along radial glial fiber is essential for the formation of cortical layers. Several neurological diseases are caused by defects in neuronal migration, underlining the importance of this process for brain function. Multiple molecules are involved in this process...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2015.02.025

    authors： Wang JT,Song LZ,Li LL,Zhang W,Chai XJ,An L,Chen SL,Frotscher M,Zhao ST

    更新日期：2015-04-30 00:00:00

  • Ultrastructural correlates of experimentally altered transmitter release efficacy in frog motor nerve terminals.

    abstract：:After experimentally inducing long term changes in transmitter release, a series of frog neuromuscular junctions were studied with intracellular recording and then semi-serially sectioned and examined in the electron microscope. Transmitter release per unit length of motor nerve terminal was well correlated with sever...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/0306-4522(85)90187-3

    authors： Herrera AA,Grinnell AD,Wolowske B

    更新日期：1985-11-01 00:00:00

  • Probiotics treatment improves diabetes-induced impairment of synaptic activity and cognitive function: behavioral and electrophysiological proofs for microbiome-gut-brain axis.

    abstract：:Diabetes mellitus-induced metabolic disturbances underlie the action of many systems including some higher functions of the brain such as learning and memory. Plenty of evidence supports the effects of probiotics on the function of many systems including the nervous system. Here we report the effect of probiotics trea...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2013.02.055

    authors： Davari S,Talaei SA,Alaei H,Salami M

    更新日期：2013-06-14 00:00:00

  • Role of nitric oxide in the ethylcholine aziridinium model of delayed apoptotic neurodegeneration in vivo and in vitro.

    abstract：:The involvement of nitric oxide in neurodegenerative processes still remains incompletely characterized. Although nitric oxide has been reported to be an important mediator in neuronal degeneration in different models of cell death involving NMDA-receptor activation, increasing evidence for protective mechanisms has b...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/s0306-4522(99)00599-0

    authors： Lautenschlager M,Onufriev MV,Gulyaeva NV,Harms C,Freyer D,Sehmsdorf U,Ruscher K,Moiseeva YV,Arnswald A,Victorov I,Dirnagl U,Weber JR,Hörtnagl H

    更新日期：2000-01-01 00:00:00

  • Effect of tricyclodecan-9-yl potassium xanthate (D609) on phospholipid metabolism and cell death during oxygen-glucose deprivation in PC12 cells.

    abstract：:Alterations in lipid metabolism play an integral role in neuronal death in cerebral ischemia. Here we used an in vitro model, oxygen-glucose deprivation (OGD) of rat pheochromocytoma (PC12) cells, and analyzed changes in phosphatidylcholine (PC) and sphingomyelin (SM) metabolism. OGD (4-8 h) of PC12 cells triggered a ...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2007.02.022

    authors： Larsen EC,Hatcher JF,Adibhatla RM

    更新日期：2007-05-25 00:00:00

  • Status epilepticus induces a TrkB to p75 neurotrophin receptor switch and increases brain-derived neurotrophic factor interaction with p75 neurotrophin receptor: an initial event in neuronal injury induction.

    abstract：:In neuronal cultures it has been demonstrated that neurotrophins can elicit neuronal death through the p75 neurotrophic receptor (p75ntr) in the absence of concomitant Trk signaling. However, it was suggested that p75ntr induces neuronal death after status epilepticus (SE) in neuronal populations that express relative...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2008.04.038

    authors： Unsain N,Nuñez N,Anastasía A,Mascó DH

    更新日期：2008-06-26 00:00:00

  • Alternative Splicing and the Intracellular Domain Mediate TM-agrin's Ability to Differentially Regulate the Density of Excitatory and Inhibitory Synapse-like Specializations in Developing CNS Neurons.

    abstract：:Agrin is a multi-domain protein best known for its essential function during formation of the neuromuscular junction. Alternative mRNA splicing at sites named y and z in the C-terminal part of agrin regulates its interaction with a receptor complex consisting of the agrin-binding low-density lipoprotein receptor-relat...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2019.09.011

    authors： Handara G,Kröger S

    更新日期：2019-11-01 00:00:00

  • Essential role of mu opioid receptor in the regulation of delta opioid receptor-mediated antihyperalgesia.

    abstract：:Analgesic effects of delta opioid receptor (DOR) -selective agonists are enhanced during persistent inflammation and arthritis. Although the underlying mechanisms are still unknown, membrane density of DOR was shown to be increased 72 h after induction of inflammation, an effect abolished in mu opioid receptor (MOR) -...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2007.09.060

    authors： Gendron L,Pintar JE,Chavkin C

    更新日期：2007-12-19 00:00:00

  • Distribution of serotonin receptor 5-HT6 mRNA in rat neuronal subpopulations: A double in situ hybridization study.

    abstract：:The 5-HT6 receptor (5-HT6R) is almost exclusively expressed in the brain and has emerged as a promising target for cognitive disorders, including Alzheimer's disease. In the present study, we have determined the cell types on which the 5-HT6R is expressed by colocalizing 5-HT6R mRNA with that of a range of neuronal an...

    journal_title：Neuroscience

    pub_type： 杂志文章

    doi：10.1016/j.neuroscience.2015.09.064

    authors： Helboe L,Egebjerg J,de Jong IE

    更新日期：2015-12-03 00:00:00