Whole transcriptome expression of trigeminal ganglia compared to dorsal root ganglia in Rattus Norvegicus.

abstract：:In vivo microdialysis was used to measure the effects of partial deafferentation of cortical cholinergic inputs on acetylcholine efflux in young (four to seven months) and aged (24-28 months) male F344/BNNIA rats. Partial deafferentation was produced by bilateral infusions of the immunotoxin 192 immunoglobulin G-sapor...

journal_title：Neuroscience

authors： Fadel J,Sarter M,Bruno JP

更新日期：1999-03-01 00:00:00

abstract：:The aim of this study was to test a possible role of A5 neurons in the expression of the pressor and tachycardic responses to conditioned fear and restraint, two forms of psychological stress. Previous Fos studies have shown that the C1 adrenergic neurons and spinally projecting neurons in the vasopressor region of th...

journal_title：Neuroscience

authors： Vianna DM,Carrive P

更新日期：2010-04-14 00:00:00

abstract：:There is increasing evidence that alterations in the focus of attention result in changes in neural responding at the most peripheral levels of the auditory system. To date, however, those studies have not ruled out differences in task demands or overall arousal in explaining differences in responding across intermoda...

journal_title：Neuroscience

authors： Srinivasan S,Keil A,Stratis K,Woodruff Carr KL,Smith DW

更新日期：2012-10-25 00:00:00

abstract：:Our study examined how different housing conditions modulated the acquisition of a spatial reference memory task and also, a reversal task in the 4-radial arm water maze (4-RAWM). The animals were randomly assigned to standard or enriched cages, and, as a type of complementary stimulation along with the environmental ...

journal_title：Neuroscience

authors： Sampedro-Piquero P,Zancada-Menendez C,Begega A

更新日期：2015-10-29 00:00:00

abstract：:Hormone therapy and estrogen therapy in postmenopausal women have been thought to ameliorate cognitive dysfunction and decrease the risk and/or progress of neurodegenerative conditions such as Alzheimer's disease and stroke. Furthermore, estrogens have been shown to exert neuroprotective actions in a variety of in vit...

journal_title：Neuroscience

authors： Wise PM

更新日期：2006-01-01 00:00:00

abstract：:In the present study, we found that amyloid-beta peptide enhanced glutamate release from primary cultured rat microglia via the Na+-dependent glutamate transporter, which was activated by extracellular K+. Glutamate transport current was measured by a conventional whole-cell patch recording mode under voltage-clamp co...

journal_title：Neuroscience

authors： Noda M,Nakanishi H,Akaike N

更新日期：1999-01-01 00:00:00

abstract：:The pathophysiologic basis of tardive dyskinesia remains unclear. It has been proposed that tardive dyskinesia may be a result of excitotoxic neurodegeneration in the striatum caused by a neuroleptic-induced increase in striatal glutamate release and impaired energy metabolism. To investigate this hypothesis, haloperi...

journal_title：Neuroscience

authors： Andreassen OA,Ferrante RJ,Beal MF,Jørgensen HA

更新日期：1998-12-01 00:00:00

abstract：:Intracerebral microdialysis was employed in awake freely moving rats to investigate the effects of nociceptin/orphanin FQ receptor ligands on glutamate extracellular levels in the substantia nigra pars reticulata. Nociceptin/orphanin FQ, ineffective at 0.1 microM, induced a prolonged stimulation of nigral glutamate le...

journal_title：Neuroscience

authors： Marti M,Guerrini R,Beani L,Bianchi C,Morari M

更新日期：2002-01-01 00:00:00

abstract：:Mitochondrial defects including reduction of a key mitochondrial tricarboxylic acid cycle enzyme alpha-ketoglutarate-dehydrogenase complex (KGDHC) are characteristic of many neurodegenerative diseases. KGDHC consists of alpha-ketoglutarate dehydrogenase, dihydrolipoyl succinyltransferase (E2k), and dihydrolipoamide de...

journal_title：Neuroscience

authors： Calingasan NY,Ho DJ,Wille EJ,Campagna MV,Ruan J,Dumont M,Yang L,Shi Q,Gibson GE,Beal MF

更新日期：2008-06-02 00:00:00

abstract：:Previous work had shown that nicotinic antagonists resulted in a marked up-regulation of alpha-bungarotoxin sites in chromaffin cells in culture. The present experiments were done to determine the intracellular mechanism(s) whereby nicotinic antagonists might mediate their effects on these receptors. Chromaffin cells ...

journal_title：Neuroscience

authors： Geertsen S,Afar R,Trifaró JM,Quik M

更新日期：1990-01-01 00:00:00

abstract：:Classic neurotransmitter phenotypes are generally predetermined and develop as a consequence of target-independent lineage decisions. A unique mode of target-dependent phenotype instruction is the acquisition of the cholinergic phenotype in the peripheral sympathetic nervous system. A body of work suggests that the sw...

journal_title：Neuroscience

authors： Schütz B,von Engelhardt J,Gördes M,Schäfer MK,Eiden LE,Monyer H,Weihe E

更新日期：2008-10-02 00:00:00

abstract：:This good laboratory practice (GLP) study of aluminum salts in Sprague-Dawley rats was conducted according to double-blind, vehicle-controlled randomized design by exposing offspring to aluminum citrate in-utero, through lactation, and then in drinking water post-weaning. Three dose levels were used: 30, 100, 300 mg A...

journal_title：Neuroscience

authors： Poirier J,Semple H,Davies J,Lapointe R,Dziwenka M,Hiltz M,Mujibi D

更新日期：2011-10-13 00:00:00

abstract：:On guinea-pig neocortical slices the spatial organization of dendrites sensitive to excitatory amino acids was studied. Extracellular recording were obtained from the the soma of layer V neurons. Responses of 135 neurons to iontophoretically applied glutamate or aspartate have been analysed. An increased firing rate t...

journal_title：Neuroscience

authors： Mednikova YS,Karnup SV

更新日期：1995-11-01 00:00:00

abstract：:Up-regulation of proBDNF in ischemic brain and the detrimental role of proBDNF on cellular survival has already been established. We propose that the up-regulated proBDNF may trigger the harmful events and evoke a secondary ischemic damage after ischemia. This study aimed to establish the neuroprotective effects of an...

journal_title：Neuroscience

authors： Rahman M,Luo H,Bobrovskaya L,Zhou XF

更新日期：2020-10-15 00:00:00

abstract：:This study was designed to examine the effect of voluntary exercise on hippocampal long-term potentiation (LTP) in morphine-dependent rats. The rats were randomly distributed into the saline-sedentary (Sal/Sed), the dependent-sedentary, the saline-exercise (Sal/Exc), and the dependent-exercise (D/Exc) groups. The Sal/...

journal_title：Neuroscience

authors： Miladi-Gorji H,Rashidy-Pour A,Fathollahi Y,Semnanian S,Jadidi M

更新日期：2014-01-03 00:00:00

abstract：:Temporal lobe epilepsy (TLE) is the most common form of focal epilepsies in adults. It is often initiated by an insult or brain injury which triggers a series of alterations which ultimately lead to seizures (epilepsy). In 50-70% of people with TLE the condition cannot be adequately treated by the present antiepilepti...

journal_title：Neuroscience

authors： van Vliet EA,Aronica E,Gorter JA

更新日期：2014-09-26 00:00:00

abstract：:In the olfactory system, the endocannabinoid system (ECS) regulates sensory perception and memory. A major structure involved in these processes is the anterior piriform cortex (aPC), but the impact of ECS signaling in aPC circuitry is still scantly characterized. Using ex vivo patch clamp experiments in mice and neur...

journal_title：Neuroscience

authors： Terral G,Varilh M,Cannich A,Massa F,Ferreira G,Marsicano G

更新日期：2020-05-01 00:00:00

abstract：:To be highly reliable, synaptic transmission needs postsynaptic receptors (Rs) in precise apposition to the presynaptic release sites. At inhibitory synapses, the postsynaptic protein gephyrin self-assembles to form a scaffold that anchors glycine and GABAARs to the cytoskeleton, thus ensuring the accurate accumulatio...

journal_title：Neuroscience

authors： Pizzarelli R,Griguoli M,Zacchi P,Petrini EM,Barberis A,Cattaneo A,Cherubini E

更新日期：2020-07-15 00:00:00

abstract：:After loading cultured rat hippocampal neurons with teh acetoxymethyl ester of the Ca2+ buffer BAPTA, or its dimethyl analogue DMB, the magnitudes of transient (20-25 s) depolarization- or excitatory amino acid-induced Ca2+ responses were reduced, as were the rates of increase and recovery of [Ca2+]i. In contrast, dur...

journal_title：Neuroscience

authors： Abdel-Hamid KM,Baimbridge KG

更新日期：1997-12-01 00:00:00

abstract：:The nucleus of the solitary tract is the site of termination of primary afferent fibers running in the facial, glossopharyngeal and vagus nerves. The present study was performed to map the distribution of glutamatergic axons terminals in the rat nucleus of the solitary tract using immunodetection of vesicular glutamat...

journal_title：Neuroscience

authors： Lachamp P,Crest M,Kessler JP

更新日期：2006-01-01 00:00:00

abstract：:Neurotransmitter release regulation is highly heterogeneous across the brain. The fundamental units of release, individual boutons, are difficult to access and poorly understood. Here we directly activated single boutons on mechanically isolated nucleus tractus solitarius (NTS) neurons to record unitary synaptic event...

journal_title：Neuroscience

authors： Jin YH,Andresen MC

更新日期：2011-10-13 00:00:00

abstract：:Tolerance to the analgesic effects of morphine results in part from the development of a compensatory response in neurons that express the opioid receptor or of neural circuits in which those neurons participate. According to this formulation, withdrawal of morphine results in an overshoot of several neuronal properti...

journal_title：Neuroscience

authors： Rohde DS,Detweiler DJ,Basbaum AI

更新日期：1996-05-01 00:00:00

abstract：:Exercise reduces the risk of developing a number of neurological disorders and increases the efficiency of cellular energy production. However, overly strenuous exercise produces oxidative stress. Proper oxygenation is crucial for the health of all tissues, and tight regulation of cellular oxygen is critical to balanc...

journal_title：Neuroscience

authors： Smeyne M,Sladen P,Jiao Y,Dragatsis I,Smeyne RJ

更新日期：2015-06-04 00:00:00

abstract：:The electrical activity of 132 neurons located in the inhibitory area of the medullary reticular formation, namely, in the medial aspects of the nucleus reticularis gigantocellularis, magnocellularis and ventralis has been recorded in precollicular decerebrate cats during sinusoidal displacement of the neck. This was ...

journal_title：Neuroscience

authors： Srivastava UC,Manzoni D,Pompeiano O,Stampacchia G

更新日期：1984-02-01 00:00:00

abstract：:The amygdala is a temporal lobe region that is implicated in emotional information processing. The amygdala also is associated with the processing and modulation of pain sensation. Recently, we demonstrated that in nonhuman primates, the amygdala is necessary for the full expression of cannabinoid-induced antinocicept...

journal_title：Neuroscience

authors： Manning BH,Martin WJ,Meng ID

更新日期：2003-01-01 00:00:00

abstract：:Mutations in γ-aminobutyric acid A receptor (GABAA) subunits and sodium channel genes, especially GABRG2 and SCN1A, have been reported to be associated with febrile seizures (FS) and genetic epilepsy with febrile seizures plus (GEFS+). GEFS+ is a well-known family of epileptic syndrome with autosomal dominant inherita...

journal_title：Neuroscience

authors： Li X,Guo S,Liu K,Zhang C,Chang H,Yang W,Rong S,Hu Q,Cui J,Wang F,Sun T

更新日期：2020-07-01 00:00:00

abstract：:Since functional imaging of whole body movements is not feasible with functional magnetic resonance imaging (fMRI), the present study presents in vivo functional near-infrared spectroscopy (fNIRS) as a suitable technique to measure body movement effects on fronto-temporo-parietal cortical activation in single- and dua...

journal_title：Neuroscience

authors： Metzger FG,Ehlis AC,Haeussinger FB,Schneeweiss P,Hudak J,Fallgatter AJ,Schneider S

更新日期：2017-02-20 00:00:00

abstract：:Carbon monoxide (CO), like other gaseous neuromodulators, has a dual nature as both a toxic gas and a physiologically relevant signaling molecule. In the nervous system, high concentrations of CO can lead to neuronal injury while lower concentrations are found to be neuroprotective. The number of cellular targets affe...

journal_title：Neuroscience

authors： Estes S,Zhong LR,Artinian L,Rehder V

更新日期：2015-12-17 00:00:00

abstract：:Sensory neurons mediate diabetic peripheral neuropathy. Using a mouse model of diabetic peripheral neuropathy (BKS.Cg-m+/+Lepr(db)/J (db/db) mice) and cultured dorsal root ganglion (DRG) neurons, the present study showed that hyperglycemia downregulated miR-146a expression and elevated interleukin-1 receptor-activated...

journal_title：Neuroscience

authors： Wang L,Chopp M,Szalad A,Zhang Y,Wang X,Zhang RL,Liu XS,Jia L,Zhang ZG

更新日期：2014-02-14 00:00:00

abstract：:Several isoforms of integrin subunits are expressed in Schwann cells and mediate Schwann cell interactions with axons. Here, we identify α6 and β1 integrins as heterodimeric proteins expressed in Schwann cells and define their functions in axonal regeneration. α6 and β1 integrins are induced in Schwann cells in the sc...

journal_title：Neuroscience

authors： Chang IA,Kim KJ,Namgung U

更新日期：2018-02-10 00:00:00