Requirement of histidine kinases HP0165 and HP1364 for acid resistance in Helicobacter pylori.

abstract：:L-phase variants and small colony (G-phase) variants derived from penicillinase-producing Staphylococcus aureus strains were tested for penicillinase (beta lactamase) production. A refined variation of the modified Gots test for penicillinase was used to demonstrate penicillinase synthesis. Penicillinase synthesis was...

journal_title：Infection and immunity

authors： Simon HJ,Yin EJ

更新日期：1970-11-01 00:00:00

abstract：:Syphilis has been recognized as a disease since the late 1400s, yet there is no practical vaccine available. One impediment to the development of a vaccine is the lack of understanding of multiple reinfections in humans despite the development of robust immune responses during the first episode. It has been shown that...

journal_title：Infection and immunity

authors： Morgan CA,Lukehart SA,Van Voorhis WC

更新日期：2003-10-01 00:00:00

abstract：:The ability to bind and utilize hemin is a trait common to many human pathogens. Nevertheless, the relationship between Legionella pneumophila, the agent of Legionnaires' disease, and hemin has received little attention. Thus, we explored the capacity of a virulent, serogroup 1 strain of L. pneumophila to bind hemin a...

journal_title：Infection and immunity

authors： O'Connell WA,Hickey EK,Cianciotto NP

更新日期：1996-03-01 00:00:00

abstract：:In vitro or animal models have been used to investigate the pathogenesis of Helicobacter pylori infection. However, extrapolation to humans of results obtained with these heterologous models remains difficult. We have developed a new model for the study of H. pylori infection that uses human entire embryonic stomachs ...

journal_title：Infection and immunity

authors： Lozniewski A,Muhale F,Hatier R,Marais A,Conroy MC,Edert D,le Faou A,Weber M,Duprez A

更新日期：1999-04-01 00:00:00

abstract：:Both interleukin-17A (IL-17A) and IL-17F are proinflammatory cytokines that have an important role in intestinal homeostasis via receptor signaling. These cytokines have been characterized in chickens, but very little is known about their receptors and their functional activity. We provide here the first description o...

journal_title：Infection and immunity

authors： Kim WH,Jeong J,Park AR,Yim D,Kim S,Chang HH,Yang SH,Kim DH,Lillehoj HS,Min W

更新日期：2014-09-01 00:00:00

abstract：:The tetrasaccharide 3-deoxy-alpha-D-manno-2-octulosonic acid (alpha-KDO) (2----8)-alpha-KDO(2----4)-alpha-KDO(2----6)-beta GlcNAc, a partial structure of chlamydial lipopolysaccharide (LPS) representing a genus-specific epitope, was synthesized and covalently linked to bovine serum albumin, resulting in an artificial ...

journal_title：Infection and immunity

authors： Fu Y,Baumann M,Kosma P,Brade L,Brade H

更新日期：1992-04-01 00:00:00

abstract：:Bacterial lipopolysaccharide (LPS) is a potent stimulus of cells, yet a target protein for LPS has not been defined. We used two approaches to define LPS-binding sites on cell surfaces: one assay measured binding of LPS-coated erythrocytes (ELPS) to cultured human cells, and a second measured binding of a radiolabeled...

journal_title：Infection and immunity

authors： Golenbock DT,Hampton RY,Raetz CR,Wright SD

更新日期：1990-12-01 00:00:00

abstract：:The filarial nematode Onchocerca volvulus is the causative organism of river blindness. Our previous studies demonstrated an essential role for endosymbiotic Wolbachia bacteria in corneal disease, which is characterized by neutrophil infiltration into the corneal stroma and the development of corneal haze. To determin...

journal_title：Infection and immunity

authors： Gillette-Ferguson I,Daehnel K,Hise AG,Sun Y,Carlson E,Diaconu E,McGarry HF,Taylor MJ,Pearlman E

更新日期：2007-12-01 00:00:00

abstract：:Because of the unavailability of a suitable antigen, specific in vitro lymphocyte reactivity has not been investigated in persons who have had systemic blastomycosis. Twelve persons who had recovered from blastomycosis were evaluated, and all were found to exhibit strongly positive and apparently specific in vitro cel...

journal_title：Infection and immunity

authors： Bradsher RW,Alford RH

更新日期：1981-08-01 00:00:00

abstract：:Strains of Bacteroides fragilis associated with diarrhea in children (termed enterotoxigenic B. fragilis, or ETBF) produce a heat-labile ca. 20-kDa protein toxin (BFT). The purpose of this study was to examine the activity of BFT on polarized monolayers of human intestinal epithelial cells (T84 cells). In Ussing chamb...

journal_title：Infection and immunity

authors： Chambers FG,Koshy SS,Saidi RF,Clark DP,Moore RD,Sears CL

更新日期：1997-09-01 00:00:00

abstract：:We examined the way the major outer membrane protein OmpA of Salmonella enterica serovar Typhimurium is recognized by the mouse immune system, by raising a panel of 12 monoclonal antibodies (MAbs) against this protein. Interaction between OmpA and these MAbs is competitively inhibited with several-hundredfold dilution...

journal_title：Infection and immunity

authors： Singh SP,Williams YU,Miller S,Nikaido H

更新日期：2003-07-01 00:00:00

abstract：:Effector mechanisms resulting from alternative complement pathway (ACP) activation cannot act efficiently against Yersinia enterocolitica serotype O3, as indicated by poor C3 to C9 consumption and by survival in EGTA (ethyleneglycoldiaminetetraacetic acid) Mg-serum. These results were not influenced by the lack or pre...

journal_title：Infection and immunity

authors： Wachter E,Brade V

更新日期：1989-07-01 00:00:00

abstract：:Antimicrobial peptides play an important role in host defense against Vibrio cholerae Generally, the V. cholerae O1 classical biotype is polymyxin B (PB) sensitive and El Tor is relatively resistant. Detection of classical biotype traits like the production of classical cholera toxin and PB sensitivity in El Tor strai...

journal_title：Infection and immunity

authors： Samanta P,Mandal RS,Saha RN,Shaw S,Ghosh P,Dutta S,Ghosh A,Imamura D,Morita M,Ohnishi M,Ramamurthy T,Mukhopadhyay AK

更新日期：2020-04-20 00:00:00

abstract：:Neisseria gonorrhoeae, the causative agent of the sexually transmitted infection (STI) gonorrhea, is a growing public health threat for which a vaccine is urgently needed. We characterized the functional role of the gonococcal MetQ protein, which is the methionine binding component of an ABC transporter system, and as...

journal_title：Infection and immunity

authors： Semchenko EA,Day CJ,Seib KL

更新日期：2017-01-26 00:00:00

abstract：:Patent filarial infection is associated with the downregulation of parasite-specific immune reactivity. In the present study, the relationship between in vitro parasite antigen-specific humoral and cellular immune responsiveness was investigated in Brugia pahangi-infected jirds and in jirds immunized with soluble anti...

journal_title：Infection and immunity

authors： Prier RC,Lammie PJ

更新日期：1988-12-01 00:00:00

abstract：:The amount of crude Campylobacter jejuni enterotoxin present in culture products was quantitated by comparing the response of these preparations with that of pure Escherichia coli heat-labile toxin (LT) in the Chinese hamster ovary assay and in enzyme-linked immunosorbent assays that used GM ganglioside or antisera to...

journal_title：Infection and immunity

authors： Klipstein FA,Engert RF

更新日期：1984-08-01 00:00:00

abstract：:The generation of leukotrienes (LTC4, LTD4, LTE4, and LTB4; 12-epi-LTB4 isomer) from human granulocytes by thiol-activated toxins (streptolysin O, alveolysin from Bacillus alvei, and theta toxin from Clostridium perfringens) is described. The release occurs under noncytolytic conditions. Although LTB4 is the major com...

journal_title：Infection and immunity

authors： Bremm KD,König W,Pfeiffer P,Rauschen I,Theobald K,Thelestam M,Alouf JE

更新日期：1985-12-01 00:00:00

abstract：:Bordetella dermonecrotizing toxin (DNT) stimulates the assembly of actin stress fibers and focal adhesions by deamidating Gln63 of the small GTPase Rho. To clarify the functional and structural organization of DNT, we cloned and sequenced the DNT gene and examined the functions of various DNT mutants. Our analyses of ...

journal_title：Infection and immunity

authors： Kashimoto T,Katahira J,Cornejo WR,Masuda M,Fukuoh A,Matsuzawa T,Ohnishi T,Horiguchi Y

更新日期：1999-08-01 00:00:00

abstract：:We have determined the nucleotide sequence of the 1.4-kilobase DNA fragment containing the plasminogen activator gene (pla) of Yersinia pestis, which determines both plasminogen activator and coagulase activities of the species. The sequence revealed the presence of a 936-base-pair open reading frame that constitutes ...

journal_title：Infection and immunity

authors： Sodeinde OA,Goguen JD

更新日期：1989-05-01 00:00:00

abstract：:Herpes simplex virus type 1 (HSV-1) glycoprotein gC was purified by affinity chromatography with an immunosorbent column containing monoclonal antibody to HSV-1 gC, and its reactivity with rabbit antisera was measured by enzyme-linked immunosorbent assay and sodium dodecyl sulfate-polyacrylamide gel electrophoretic an...

journal_title：Infection and immunity

authors： Zweig M,Heilman CJ Jr,Bladen SV,Showalter SD,Hampar B

更新日期：1983-08-01 00:00:00

abstract：:Adult volunteers received a booster dose (4 x 10(8) CFU) of attenuated Vibrio cholerae CVD 103-HgR oral vaccine 15 or 24 months after primary immunization. The immune response was modest, presumably due to rapid clearance of the vaccine strain by a primed immune system. ...

journal_title：Infection and immunity

authors： Cryz SJ Jr,Levine MM,Losonsky G,Kaper JB,Althaus B

更新日期：1992-09-01 00:00:00

abstract：:Monoclonal antibodies were produced against the HAR-13 strain (A) of Chlamydia trachomatis. By an indirect immunofluorescence technique, three clones (1-7, 2-8, 9F) were found to produce antibody that reacted only with serotype A strains. Clone 3-5 produced antibody that cross-reacted with serotypes A, C, H, I, and J....

journal_title：Infection and immunity

authors： Clark RB,Nachamkin I,Schatzki PF,Dalton HP

更新日期：1982-12-01 00:00:00

abstract：:We report the cloning and expression of Ac-GST-1, a novel glutathione S-transferase from the adult hookworm Ancylostoma caninum, and its possible role in parasite blood feeding and as a vaccine target. The predicted Ac-GST-1 open reading frame contains 207 amino acids (mass, 24 kDa) and exhibited up to 65% amino acid ...

journal_title：Infection and immunity

authors： Zhan B,Liu S,Perally S,Xue J,Fujiwara R,Brophy P,Xiao S,Liu Y,Feng J,Williamson A,Wang Y,Bueno LL,Mendez S,Goud G,Bethony JM,Hawdon JM,Loukas A,Jones K,Hotez PJ

更新日期：2005-10-01 00:00:00

abstract：:Hydrogen peroxide (H2O2) is a by-product of glycerol metabolism in mycoplasmas and has been shown to cause cytotoxicity for cocultured eukaryotic cells. There appears to be selective pressure for mycoplasmas to retain the genes needed for glycerol metabolism. This has generated interest and speculation as to their fun...

journal_title：Infection and immunity

authors： Szczepanek SM,Boccaccio M,Pflaum K,Liao X,Geary SJ

更新日期：2014-12-01 00:00:00

abstract：:Some clinical strains of Vibrio cholerae non-O1 produce an extracellular factor that evokes a rapid and dramatic cytotoxic response which manifests as cell rounding of Chinese hamster ovary (CHO) and HeLa cells without accompanying membrane damage. This study was performed to establish the identity of the non-membrane...

journal_title：Infection and immunity

authors： Saha PK,Koley H,Nair GB

更新日期：1996-08-01 00:00:00

abstract：:γ9δ2 T cells provide a natural bridge between innate and adaptive immunity, rapidly and potently respond to pathogen infection in mucosal tissues, and are prominently induced by both tuberculosis (TB) infection and bacillus Calmette Guérin (BCG) vaccination. Mycobacterium-expanded γ9δ2 T cells represent only a subset ...

journal_title：Infection and immunity

authors： Xia M,Hesser DC,De P,Sakala IG,Spencer CT,Kirkwood JS,Abate G,Chatterjee D,Dobos KM,Hoft DF

更新日期：2016-08-19 00:00:00

abstract：:The adherence of Trichomonas vaginalis NYH 286 to host cells was evaluated by using monolayer cultures of HeLa and HEp-2 epithelial cells and human fibroblast cell lines. Saturation of sites on HeLa cells was achieved, yielding a maximal T. vaginalis NYH 286-to-cell ratio of two. The ability of radiolabeled NYH 286 to...

journal_title：Infection and immunity

authors： Alderete JF,Garza GE

更新日期：1985-12-01 00:00:00

abstract：:The type III secretion system (T3SS) encoded by the Salmonella pathogenicity island 2 (SPI2) has a central role in systemic infections by Salmonella enterica and for the intracellular phenotype. Intracellular S. enterica uses the SPI2-encoded T3SS to translocate a set of effector proteins into the host cell, which mod...

journal_title：Infection and immunity

authors： Hansen-Wester I,Chakravortty D,Hensel M

更新日期：2004-05-01 00:00:00

abstract：:The symptoms of Lyme disease are caused by inflammation induced by species of the Borrelia burgdorferisensu lato complex. The various presentations of Lyme disease in the population suggest that differences exist in the intensity and regulation of the host response to the spirochete. Previous work has described correl...

journal_title：Infection and immunity

authors： Siebers EM,Liedhegner ES,Lawlor MW,Schell RF,Nardelli DT

更新日期：2020-10-19 00:00:00

abstract：:The acute phase of Chagas' disease is accompanied by immunosuppression. To explore the underlying mechanism(s), we used an in vitro culture system in which the capacities of activated human peripheral blood mononuclear cells to express interleukin-2 receptors (IL-2R) and proliferate are markedly inhibited in the prese...

journal_title：Infection and immunity

authors： Beltz LA,Kierszenbaum F,Sztein MB

更新日期：1989-08-01 00:00:00