Abstract:
:The ionophores A23187 and bromolasalocid (Br-X537A) acted synergistically in translocating Ca(2+) from an aqueous into an organic immiscible phase or in mediating Ca(2+) transport across the organic phase, the effects obtained in the simultaneous presence of both ionophores being greater than those expected from a summation of the individual effects of each ionophore. The nuclear magnetic resonance spectrum obtained when the complexation of Ca(2+) occurred in the presence of both ionophores differed strikingly from the individual spectra obtained with the A23187-Ca and Br-X537A-Ca complexes. These findings indicate that the two ionophores are able to form hybrid complexes with Ca(2+).
journal_name
Proc Natl Acad Sci U S Aauthors
Deleers M,Gelbcke M,Malaisse WJdoi
10.1073/pnas.78.1.279subject
Has Abstractpub_date
1981-01-01 00:00:00pages
279-82issue
1eissn
0027-8424issn
1091-6490journal_volume
78pub_type
杂志文章abstract::Cedar virus (CedV) is a bat-borne henipavirus related to Nipah virus (NiV) and Hendra virus (HeV), zoonotic agents of fatal human disease. CedV receptor-binding protein (G) shares only ∼30% sequence identity with those of NiV and HeV, although they can all use ephrin-B2 as an entry receptor. We demonstrate that CedV a...
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journal_title:Proceedings of the National Academy of Sciences of the United States of America
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