当前位置： SCI文献检索 > JOURNAL OF CLINICAL PERIODONTOLOGY期刊下所有文献 > Supportive periodontal therapy using mechanical instrumentation or 2% minocycline gel: a 12 month randomized, controlled, single masked pilot study.

Supportive periodontal therapy using mechanical instrumentation or 2% minocycline gel: a 12 month randomized, controlled, single masked pilot study.

Abstract：

OBJECTIVE:To compare the short-term performance of subgingival local delivery of 2% minocycline gel and conventional subgingival debridement in supportive periodontal therapy (SPT) patients. METHODS:Forty adult patients having completed active treatment for moderate to advanced chronic periodontitis were included in a randomized, controlled, single masked maintenance care pilot study. Sites with residual pocket probing depths > or =5 mm and bleeding on probing were treated with either minocycline gel (minocycline-group) or scaling and root planing only (debridement-group) at baseline, 3, 6, and 9 months. Clinical and microbiological examinations were performed at baseline, 3, 6, 9, and 12 months. RESULTS:Full-mouth plaque and bleeding scores remained <10% and <20%, respectively, for both groups throughout the study. In both groups there was a persistent reduction in number of teeth and sites with probing pocket depths > or =5 mm (p<0.05) with no significant differences between the groups. The prevalence of Porphyromonas gingivalis, Tannerella forsythia, Treponema denticola, Actinobacillus actinomycetemcomitans, Prevotella intermedia, and Prevotella nigrescens, remained at levels < or =10(5) in the majority of patients and sites in both groups. CONCLUSION:This pilot study failed to show a difference between local delivery of 2% minocycline gel as mono-therapy and traditional subgingival debridement in patients on SPT.

journal_name

J Clin Periodontol

journal_title

Journal of clinical periodontology

authors

McColl E,Patel K,Dahlen G,Tonetti M,Graziani F,Suvan J,Laurell L

doi

10.1111/j.1600-051X.2005.00879.x

keywords:

subject

Has Abstract

pub_date

2006-02-01 00:00:00

pages

141-50

issue

2

eissn

0303-6979

issn

1600-051X

pii

CPE879

journal_volume

33

pub_type

杂志文章,随机对照试验

相关文献

JOURNAL OF CLINICAL PERIODONTOLOGY文献大全
  • Effect of ultrasonic debridement using a chlorhexidine irrigant on circulating levels of lipopolysaccharides and interleukin-6.

    abstract：AIM:Transient bacteraemia and endotoxaemia, and elevated levels of systemic cytokines have been reported following subgingival debridement. This study aimed to investigate the effect of chlorhexidine (CHX) solution on circulating levels of lipopolysaccharide (LPS) and interleukin-6 (IL-6) when used as an irrigant durin...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章,随机对照试验

    doi：10.1111/j.1600-051X.2008.01221.x

    authors： Lee MK,Ide M,Coward PY,Wilson RF

    更新日期：2008-05-01 00:00:00

  • Soft tissue volume augmentation at dental implant sites using a volume stable three-dimensional collagen matrix - histological outcomes of a preclinical study.

    abstract：AIM:The aim of this study was to test whether or not soft tissue augmentation with a collagen matrix (VCMX) leads to a similar increase in ridge width around dental implants compared to the use of an autogenous subepithelial connective tissue graft (SCTG). MATERIALS AND METHODS:In 12 dogs, immediate dental implants we...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1111/jcpe.12635

    authors： Thoma DS,Naenni N,Benic GI,Hämmerle CH,Jung RE

    更新日期：2017-02-01 00:00:00

  • Interleukin-1 gene polymorphism and periodontal status. A case-control study.

    abstract：OBJECTIVES:This case-control study examined polymorphisms at the interleukin-1 gene in relation to periodontal status, subgingival bacteria and systemic antibodies to periodontal microbiota. METHODS:132 periodontitis patients were age- and gender-matched with 73 periodontally intact controls. Full-mouth clinical asses...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1034/j.1600-051x.2001.028005389.x

    authors： Papapanou PN,Neiderud AM,Sandros J,Dahlén G

    更新日期：2001-05-01 00:00:00

  • Periodontal repair in dogs: space-providing ePTFE devices increase rhBMP-2/ACS-induced bone formation.

    abstract：BACKGROUND:Recombinant human bone morphogenetic protein-2 (rhBMP-2) technologies have been shown to enhance alveolar bone formation significantly. Biomaterial (carrier) limitations, however, have restricted their biologic potential for indications where compressive forces may limit the volume of bone formed. The object...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1034/j.1600-051x.2003.00364.x

    authors： Wikesjö UM,Xiropaidis AV,Thomson RC,Cook AD,Selvig KA,Hardwick WR

    更新日期：2003-08-01 00:00:00

  • C-reactive protein in patients with coexistent periodontal disease and acute coronary syndromes.

    abstract：AIM:To evaluate periodontal disease (PD) influence on changes in high-sensitivity C-reactive protein (hsCRP) concentrations in patients with acute coronary syndromes and coexistent PD. MATERIALS AND METHODS:Dental examinations were carried out in a group of 50 consecutive patients, less than 60 years old, hospitalized...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1111/j.1600-051X.2006.00931.x

    authors： Czerniuk MR,Górska R,Filipiak KJ,Opolski G

    更新日期：2006-06-01 00:00:00

  • Healing of the dento-epithelial junction following the use of dental floss.

    abstract：:The healing of the dento-epithelial junction following the use of dental floss was studied on 28 first premolars in seven children who were under orthodontic treatment. On the mesial surfaces the floss was brought to the depth of the pocket and moved back and forth three to five times, while being pressed against the ...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1111/j.1600-051x.1981.tb02354.x

    authors： Waerhaug J

    更新日期：1981-04-01 00:00:00

  • Intra- and extra-oral halitosis: finding of a new form of extra-oral blood-borne halitosis caused by dimethyl sulphide.

    abstract：AIM:The aim of this study was to unravel the origen and cause of intra-oral and extra-oral halitosis. MATERIAL AND METHODS:We studied 58 patients complaining of halitosis, using gas chromatography of volatile sulphur compounds (VSCs) in mouth and nose breath, organoleptic scoring of mouth and nose breath, Halimeter re...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1111/j.1600-051X.2007.01116.x

    authors： Tangerman A,Winkel EG

    更新日期：2007-09-01 00:00:00

  • MMP3 and TIMP1 variants contribute to chronic periodontitis and may be implicated in disease progression.

    abstract：AIM:Matrix metalloproteinases (MMPs) play a key role in the tissue destruction characteristic of chronic periodontitis. The purpose of this study was to investigate the association of MMP and TIMP polymorphisms with chronic periodontitis in two populations. MATERIAL AND METHODS:A total of 34 polymorphisms spanning 12 ...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1111/j.1600-051X.2012.01902.x

    authors： Letra A,Silva RM,Rylands RJ,Silveira EM,de Souza AP,Wendell SK,Garlet GP,Vieira AR

    更新日期：2012-08-01 00:00:00

  • A "case control" study on the rôle of HLA DR4 in severe periodontitis and rapidly progressive periodontitis. Identification of types and subtypes using molecular biology (PCR.SSO).

    abstract：:HLA DR4 antigens have been considered as a risk factor in periodontal disease. The aim of this "case control" study was to verify and to provide fuller clarification of such data. "Cases" or patients had to be aged between 20 and 48 years. They presented at least 5 sites spread over several teeth with an attachment lo...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1034/j.1600-051x.1999.260203.x

    authors： Bonfil JJ,Dillier FL,Mercier P,Reviron D,Foti B,Sambuc R,Brodeur JM,Sedarat C

    更新日期：1999-02-01 00:00:00

  • Digital subtraction radiography in assessing bone changes in periodontal defects following guided tissue regeneration.

    abstract：:19 patients with a total of 23 periodontal lesions were selected for the study. Following flap-elevation, an occlusive membrane (Gore Tex) adjusted to the size and shape of the lesion was applied. The membrane was removed 4-6 weeks later by a 2nd operation. Clinical attachment levels were measured and intraoral radiog...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1111/j.1600-051x.1992.tb00641.x

    authors： Wenzel A,Warrer K,Karring T

    更新日期：1992-03-01 00:00:00

  • Actinobacillus actinomycetemcomitans in Chinese adults. Serotype distribution and analysis of the leukotoxin gene promoter locus.

    abstract：:The aim of the present study was to examine the Actinobacillus actinomycetemcomitans carrier rate in Chinese subjects, and to determine serotype distribution, presence of the leukotoxin gene lktA and the structure of the lktA-promoter region. Subgingival microbiological samples were obtained from 31 Chinese subjects w...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1034/j.1600-051x.1999.260803.x

    authors： Mombelli A,Gmür R,Lang NP,Corbert E,Frey J

    更新日期：1999-08-01 00:00:00

  • Evidence grade associating periodontitis with preterm birth and/or low birth weight: II: a systematic review of randomized trials evaluating the effects of periodontal treatment.

    abstract：AIM:The aim of this systematic review was to evaluate whether maternal periodontal disease treatment (MPDT) can reduce the incidence of preterm birth (PB) and/or low birth weight (LBW). METHODS:The Cochrane Central Register of Controlled Trials, MEDLINE and EMBASE were searched for entries up to October 2010 without r...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章,meta分析,评审

    doi：10.1111/j.1600-051X.2011.01761.x

    authors： Chambrone L,Pannuti CM,Guglielmetti MR,Chambrone LA

    更新日期：2011-10-01 00:00:00

  • Cleaning effectiveness of chewing sticks among Tanzanian schoolchildren.

    abstract：:The oral hygiene of habitual chewing stick and toothbrush users who participated in an oral health education (OHE) programme in schools was evaluated. The study comprised all chewing stick users (n = 45) in standard 4 in 8 randomly selected experimental schools and all chewing stick users (n = 17) in standard 4 in 4 r...

    journal_title：Journal of clinical periodontology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1111/j.1600-051x.1992.tb01157.x

    authors： van Palenstein Helderman WH,Munck L,Mushendwa S,Mrema FG

    更新日期：1992-08-01 00:00:00

  • Multi-centre, randomized clinical trial on the efficacy and safety of recombinant human platelet-derived growth factor with β-tricalcium phosphate in human intra-osseous periodontal defects.

    abstract：AIM:the objective of the study was to evaluate the safety and efficacy of a formulation containing recombinant human platelet-derived growth factor (rhPDGF-BB) and β-tricalcium phosphate (β-TCP) in patients with periodontal defects and to compare it with those of β-TCP alone. MATERIALS AND METHODS:in this double-blind...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1111/j.1600-051X.2010.01639.x

    authors： Jayakumar A,Rajababu P,Rohini S,Butchibabu K,Naveen A,Reddy PK,Vidyasagar S,Satyanarayana D,Pavan Kumar S

    更新日期：2011-02-01 00:00:00

  • Occurrence and risk indicators of increased probing depth in an adult Brazilian population.

    abstract：BACKGROUND/AIMS:There is little information about the occurrence and risk indicators for periodontal diseases in Latin America. The present study describes the prevalence, extent and severity of periodontal probing depth (PPD) and assesses the association between demographic, behavioural and environmental risk indicato...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1111/j.1600-051X.2005.00637.x

    authors： Susin C,Valle P,Oppermann RV,Haugejorden O,Albandar JM

    更新日期：2005-02-01 00:00:00

  • Crevicular fluid prostaglandin E2 levels in periodontitis-resistant and periodontitis-susceptible adults.

    abstract：:The aim of this cross-sectional study was to determine concentrations of prostaglandin E2 (PGE2) in gingival crevicular fluid (GCF) in a cohort of periodontal disease-resistant (PDR) adults with chronic gingivitis but with minimal evidence of bone loss, and to compare these data with GCF-PGE2 levels in patients with u...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1111/j.1600-051x.1998.tb02405.x

    authors： Heasman PA,Lauffart BL,Preshaw PM

    更新日期：1998-12-01 00:00:00

  • Prevalence of Actinobacillus actinomycetemcomitans and clinical conditions in children and adolescents from rural and urban areas of central Italy.

    abstract：BACKGROUND:The aim of this study was to report on the prevalence of Actinobacillus actinomycetemcomitans (Aa) and the periodontal clinical conditions in children and adolescents from a rural area of central Italy compared with the ones from an urban area of the same region. METHOD:The study population consisted of 780...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1034/j.1600-051x.2000.027008549.x

    authors： Paolantonio M,di Bonaventura G,di Placido G,Tumini V,Catamo G,di Donato A,Piccolomini R

    更新日期：2000-08-01 00:00:00

  • Polymorphisms of the interleukin-18 gene in periodontitis patients.

    abstract：BACKGROUND:Interleukin (IL)-18 regulates the expression of the proinflammatory cytokine interferon (IFN)-gamma. The present study sought to test the putative involvement of six different IL-18 gene polymorphisms in pre-disposition to destructive periodontal disease. METHODS:A total of 123 patients with periodontitis a...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1111/j.1600-051X.2005.00711.x

    authors： Folwaczny M,Glas J,Török HP,Tonenchi L,Paschos E,Bauer B,Limbersky O,Folwaczny C

    更新日期：2005-05-01 00:00:00

  • A critically severe gingival bleeding following non-surgical periodontal treatment in patients medicated with anti-platelet.

    abstract：BACKGROUND:Only a few dental procedures have been reported to cause life-threatening bleeding. All of these cases followed surgical intervention. MATERIAL AND METHODS:In this paper, we report a case of severe bleeding following non-surgical periodontal procedures in a patient treated with a dual anti-platelet regimen ...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1111/j.1600-051X.2008.01206.x

    authors： Elad S,Chackartchi T,Shapira L,Findler M

    更新日期：2008-04-01 00:00:00

  • Aging and microcirculatory dynamics in human gingiva.

    abstract：:There have been no published reports characterizing gingival vascular function in humans of different ages. In this study, we compared gingival vascular dynamics in 60 healthy male humans ranging in age from 18-75 years (young, 18-25 years (Y); middle, 35-45 years (M); old, 65-75 years (O), 20 subjects/group). Both vi...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1111/j.1600-051x.1993.tb00393.x

    authors： Matheny JL,Johnson DT,Roth GI

    更新日期：1993-08-01 00:00:00

  • Antibody responses to suspected periodontal pathogens in elderly subjects with periodontal disease.

    abstract：:Little is known about the relationship of aging to periodontal disease. The immune response undergoes aging-related changes resulting in loss of functional capacity. The aim of this study was to investigate the relationship between levels of serum IgG antibodies against suspected periodontal pathogenic microorganisms ...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1111/j.1600-051x.1995.tb01782.x

    authors： McArthur WP,Bloom C,Taylor M,Smith J,Wheeler T,Magnusson NI

    更新日期：1995-11-01 00:00:00

  • Labial soft tissue volume evaluation of different techniques for ridge preservation after tooth extraction: a randomized controlled clinical trial.

    abstract：OBJECTIVE:To volumetrically evaluate soft tissue changes of different ridge preservation techniques compared to spontaneous healing 6 months after tooth extraction. MATERIALS AND METHODS:In each of 40 patients, one single-rooted tooth was extracted and four treatment modalities were randomly assigned to the following ...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章,随机对照试验

    doi：10.1111/jcpe.12246

    authors： Schneider D,Schmidlin PR,Philipp A,Annen BM,Ronay V,Hämmerle CH,Attin T,Jung RE

    更新日期：2014-06-01 00:00:00

  • Effectiveness and clinical performance of early implant placement for the replacement of single teeth in anterior areas: A systematic review.

    abstract：AIM:To assess the effectiveness and clinical performance of early implant placement, 4-8 (Type 2) or 12-16 weeks (Type 3) after extraction, in single anterior sites. METHODS:Studies reporting on Type 2 and Type 3 implant placement were identified. Findings were summarized in evidence tables. Main outcome was implant s...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1111/jcpe.13092

    authors： Graziani F,Chappuis V,Molina A,Lazarin R,Schmid E,Chen S,Salvi GE

    更新日期：2019-06-01 00:00:00

  • Subgingival debridement of root surfaces with a micro-brush: macroscopic and ultrastructural assessment.

    abstract：AIM:The aim of this study was to assess the use of a micro-brush to remove plaque deposits from subgingival, periodontally involved root surfaces in vivo. METHODS:30 periodontally involved teeth requiring extraction for periodontal or prosthetic reasons in 26 adult patients were utilised. For inclusion, teeth had to d...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1034/j.1600-051x.2001.028009820.x

    authors： Carey HM,Daly CG

    更新日期：2001-09-01 00:00:00

  • Mechanical and chemical implant decontamination in surgical peri-implantitis treatment: preclinical "in vivo" study.

    abstract：OBJECTIVE:The aim of the present study was to evaluate the effect of a titanium brush and chemical agents following surgical treatment of experimental peri-implantitis. MATERIAL AND METHODS:Six implants were installed in the mandible of eight beagle dogs (unit of analysis) 3 months after tooth extraction. Experimental...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1111/jcpe.12566

    authors： Carral C,Muñoz F,Permuy M,Liñares A,Dard M,Blanco J

    更新日期：2016-08-01 00:00:00

  • Benefits of fibre retention osseous resective surgery in the treatment of shallow infrabony defects: a double-blind, randomized, clinical trial describing clinical, radiographic and patient-reported outcomes.

    abstract：BACKGROUND:The aim of this randomized clinical trial was to evaluate the efficacy of Apically Positioned Flap with Fibre Retention Osseous Resective Surgery (FibReORS) or Osseous Resective Surgery (ORS) to treat periodontal pockets associated with infrabony defect ≤3 mm at posterior natural teeth. MATERIAL AND METHODS...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章,随机对照试验

    doi：10.1111/jcpe.12042

    authors： Cairo F,Carnevale G,Nieri M,Mervelt J,Cincinelli S,Martinolli C,Pini-Prato GP,Tonetti MS

    更新日期：2013-02-01 00:00:00

  • The effect of oral irrigation with a magnetic water treatment device on plaque and calculus.

    abstract：:Calculus formation on tooth surfaces is analogous to the formation of lime and scale deposits in plumbing. Magnetic water devices have been shown to significantly reduce scale deposits in industry; therefore an oral irrigator with a magnetic water device may have a similar effect on calculus. To test this hypothesis, ...

    journal_title：Journal of clinical periodontology

    pub_type： 临床试验,杂志文章,随机对照试验

    doi：10.1111/j.1600-051x.1993.tb00366.x

    authors： Watt DL,Rosenfelder C,Sutton CD

    更新日期：1993-05-01 00:00:00

  • Gingival phenotypes in young male adults.

    abstract：:In a previous study on 42 young adult, periodontally healthy subjects without any attrition, abrasion or crown restoration, gingival thickness (GTH) was determined at facial aspects of premolars, canines and incisors by a novel ultrasonic device. GTH strongly depended on periodontal probing depth, width of gingiva (WG...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1111/j.1600-051x.1997.tb01186.x

    authors： Müller HP,Eger T

    更新日期：1997-01-01 00:00:00

  • Does obesity influence the subgingival microbiota composition in periodontal health and disease?

    abstract：AIM:To evaluate whether obesity affects the subgingival microbial composition of patients with periodontal health or chronic periodontitis (CP). MATERIALS AND METHODS:Based on periodontal parameters, body mass index and waist-hip ratio, 166 patients were allocated into one of the following groups: Normal weight (NW) p...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1111/jcpe.12634

    authors： Maciel SS,Feres M,Gonçalves TE,Zimmermann GS,da Silva HD,Figueiredo LC,Duarte PM

    更新日期：2016-12-01 00:00:00

  • Prevalence of 6 putative periodontal pathogens in subgingival plaque samples from Romanian adult periodontitis patients.

    abstract：:The aim of the present study was to determine by standard cultivation procedures the detection frequencies of Porphyromonas gingivalis, Prevotella intermedia, Fusobacterium nucleatum, Actinobacillus actinomycetemcomitans, Bacteroides forsythus, and Capnocytophaga species as well as various enteric rods in subgingival ...

    journal_title：Journal of clinical periodontology

    pub_type： 杂志文章

    doi：10.1111/j.1600-051x.1996.tb00546.x

    authors： Ali RW,Velcescu C,Jivanescu MC,Lofthus B,Skaug N

    更新日期：1996-02-01 00:00:00