Abstract：
PURPOSE:To evaluate and compare outcomes of eyes that underwent laser suture lysis (LSL) after initial trabeculectomy with mitomycin C (MMC) to those that did not require such an intervention.
METHODS:We reviewed the charts of consecutive patients with open-angle glaucoma who underwent initial trabeculectomy with mitomycin C at the Jules Stein Eye Institute between 1998 and 2003. Primary outcome measures were intraocular pressure (IOP) control at 1 year and success rate of trabeculectomy according to following criteria: criteria A, IOP < 21 mm Hg with >or=20% IOP reduction and criteria B, IOP < 15 mm Hg with >or=30% IOP reduction. Kaplan-Meier survival analysis and Cox's proportional hazards regression analysis were used to estimate and determine influence of laser suture lysis on success rates after trabeculectomy.
RESULTS:Laser suture lysis was performed in 95 eyes (84 patients) whereas 146 eyes (121 patients) did not require it. IOP was significantly higher at 12 months in laser suture lysis eyes compared with non-laser suture lysis eyes (12.9 +/- 5.2 mm Hg versus 11.0 +/- 4.1 mm Hg; P = 0.04). Laser suture lysis eyes also had decreased success rates with criteria B (57% compared with 73% at 1 year for non-LSL eyes; P = 0.005). However, only late laser suture lysis (last LSL session >10 days after trabeculectomy) was associated with worse outcome in Cox's proportional hazards model using criteria B (HR = 2.26; P = 0.004). Late hypotony occurred in 4% and 1% of non-LSL and LSL eyes, respectively.
CONCLUSIONS:Eyes that undergo laser suture lysis >10 days after initial trabeculectomy with mitomycin C are more likely to have poorer long-term IOP control than eyes not requiring laser suture lysis or eyes undergoing laser suture lysis journal_name journal_title authors doi keywords: subject pub_date pages issue eissn issn pii journal_volume pub_type
abstract：PURPOSE:To compare characteristics of functioning blebs (FBs) and nonfunctioning blebs (NFBs) with en-face spectral-domain optical coherence tomography (OCT). METHODS:We evaluated 41 blebs of 38 patients after a first-time trabeculectomy. Eyes were classified into 2 groups: FBs (22 eyes) and NFBs (19 eyes). En-face OC...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000319
更新日期：2016-05-01 00:00:00
abstract：PURPOSE:To determine if treatment with prostaglandin (PG) analogues affects keratocyte density as an indirect measure of extracellular matrix in the corneal stroma. PATIENTS AND METHODS:In this case control study, 129 eyes from 68 patients were examined: 52 eyes had only PG analogue therapy for at least 3 years, 37 ey...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e3181ca7c7a
更新日期：2010-12-01 00:00:00
abstract：PURPOSE:Estimate patient adherence to glaucoma medications and identify potential determinants of nonadherence. DESIGN:Descriptive study. METHODS:Two hundred patients with open angle glaucoma, ocular hypertension, or glaucoma suspects were interviewed regarding their glaucoma and its treatment and their charts were r...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e3181815421
更新日期：2009-03-01 00:00:00
abstract：:We determined the results of routine whole-field scotopic vision testing in consecutive patients with ocular hypertension or glaucoma who underwent Humphrey automated perimetric testing and optic disc examination. In 39 ocular hypertensive patients we found a mean threshold of 16.7 +/- 7.4 dB and in 61 glaucoma patien...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：
更新日期：1994-01-01 00:00:00
abstract：PURPOSE:To evaluate the effect of a single treatment of contact diode laser transscleral cyclophotocoagulation (TSCP) on intraocular pressure (IOP) in patients with refractory glaucoma and perform a historical meta-analysis of the relationship between successful IOP control and various laser parameters. METHODS:Clinic...
journal_title：Journal of glaucoma
pub_type： 杂志文章,meta分析
doi：10.1097/00061198-200208000-00009
更新日期：2002-08-01 00:00:00
abstract：PURPOSE:To determine the prevalence of abnormal short-wavelength automated perimetry (SWAP) visual fields in subjects with elevated intraocular pressures (IOP) for 7 existing definitions of mild glaucomatous loss, and to explore the agreement between them. PATIENTS AND METHODS:Seven hundred and forty-four eyes of 379 ...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/01.ijg.0000146363.90506.b2
更新日期：2005-02-01 00:00:00
abstract：:We report 2 bilateral cases that presented as primary ocular hypertension and primary angle-closure glaucoma, respectively; however, they were subsequently discovered to be harboring secretory pituitary tumors. After transsphenoidal tumor resection, intraocular pressures (IOPs) in all 4 eyes returned to normal levels....
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e31829521f2
更新日期：2015-03-01 00:00:00
abstract：:A 54-year-old Indian male with a diagnosis of ocular hypertension was started on a prostaglandin analog (PGA) in both eyes to lower intraocular pressure. Six years later, he developed progressively increasing bilateral limbal conjunctival hyperpigmentation. Travoprost was discontinued and replaced with brinzolamide an...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000255
更新日期：2016-01-01 00:00:00
abstract：PURPOSE:The purpose of this study was to perform a comparison of static and dynamic pupillometry measurements in patients with clinically unilateral pseudoexfoliation syndrome (PES) and age-matched controls. METHODS:This prospective cross-sectional study consisted of 38 patients with unilateral PES and 40 control part...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000953
更新日期：2018-06-01 00:00:00
abstract：PURPOSE:To evaluate the relationship between glaucomatous structural damage assessed by the Cirrus Spectral Domain OCT (SDOCT) and functional loss as measured by standard automated perimetry (SAP). METHODS:Four hundred twenty-two eyes (78 healthy, 210 suspects, 134 glaucomatous) of 250 patients were recruited from the...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e31822af27a
更新日期：2012-01-01 00:00:00
abstract：PURPOSE:To describe a simple method and outcomes of remodeling dysesthetic, oversized filtering blebs. PATIENTS AND METHODS:Retrospective chart review of the initial consecutive patients who had undergone "bleb window"-pexy (BWP) over a 1-year period. Patients with symptomatic, oversized, and dysmorphic blebs that did...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e3181815a06
更新日期：2009-09-01 00:00:00
abstract：PURPOSE:To assess the prevalence of optic disc hemorrhage in Asian patients with established glaucoma using a recently described, highly sensitive detection method. MATERIALS AND METHODS:Patients entering a trial of glaucoma filtering surgery in Southeast Asia (The Singapore 5FU Study) were assessed for the presence o...
journal_title：Journal of glaucoma
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1097/00061198-200306000-00008
更新日期：2003-06-01 00:00:00
abstract：PURPOSE:To compare the surgical outcomes between phaco-viscocanalostomy and phaco-trabeculotomy in open-angle glaucoma. PATIENTS AND METHODS:In a nonrandomized, retrospective clinical study, 110 eyes underwent phaco-viscocanalostomy (VCS group), and 110 eyes underwent phaco-trabeculotomy (LOT group). The mean follow-u...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/01.ijg.0000212265.96864.77
更新日期：2006-10-01 00:00:00
abstract：PURPOSE:To determine whether a structure-function model developed for normal age-related losses of retinal ganglion cells also models the retinal ganglion cell losses in glaucomatous optic neuropathy. METHODS:The model to relate age-related loss of retinal nerve fiber layer thickness and reduced sensitivity for standa...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e31820bcfbe
更新日期：2012-02-01 00:00:00
abstract：PURPOSE:To evaluate rates of adherence to free follow-up eye exam appointments among participants in the Philadelphia Glaucoma Detection and Treatment Project. PATIENTS AND METHODS:Ophthalmologists and testing equipment were brought directly to participants at risk for glaucoma at 43 community sites in Philadelphia. T...
journal_title：Journal of glaucoma
pub_type： 杂志文章,多中心研究
doi：10.1097/IJG.0000000000000716
更新日期：2017-08-01 00:00:00
abstract：PRCIS:Ahmed glaucoma valve implantation using the upside-down technique resulted in an aqueous humor outflow pathway, occurring primarily on the scleral side and secondarily on the conjunctival side, and was effective in treating refractory glaucoma. PURPOSE:To describe the Ahmed glaucoma valve (AGV) surgical techniqu...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000001791
更新日期：2021-01-13 00:00:00
abstract：:The recent advent of in vivo two-photon microscopy has allowed the repeat imaging of cortical structures at microscopic resolution within intact brains. Recent data obtained using this imaging technique shows that dendritic spines, the postsynaptic sites of the majority of excitatory synapses in the central nervous sy...
journal_title：Journal of glaucoma
pub_type： 杂志文章,评审
doi：10.1097/IJG.0b013e3182934a30
更新日期：2013-06-01 00:00:00
abstract：PURPOSE:To investigate the efficacy and safety of a treatment strategy with latanoprost and dorzolamide in primary pediatric glaucoma patients partially responsive to surgery. PATIENTS AND METHODS:Children with primary pediatric glaucoma having postsurgical untreated intraocular pressure (IOP) between 22 and 26 mm Hg ...
journal_title：Journal of glaucoma
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1097/IJG.0000000000000773
更新日期：2017-11-01 00:00:00
abstract：PURPOSE:To determine whether the multifocal visual evoked potential (mfVEP) technique can detect early functional damage in ocular hypertensive (OHT) and glaucoma suspect (GS) patients with normal standard achromatic automated perimetry (SAP) results. PATIENTS AND METHODS:Twenty-five GS patients (25 eyes), 25 patients...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/01.ijg.0000212237.26466.0e
更新日期：2006-08-01 00:00:00
abstract：PURPOSE:Pseudoexfoliation (PEX) syndrome, an age-related, systemic, elastic microfibrillopathy, is characterized by fibrillar-granular deposits in the anterior segment of the eye. Although not representing a true amyloidosis, PEX syndrome shares some features with amyloid disorders, such as Alzheimer disease. It has be...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e3181ca76c4
更新日期：2010-10-01 00:00:00
abstract：PURPOSE:To report plateau iris configuration (PIC) in subjects who have the long anterior zonule (LAZ) clinical trait. METHODS:Two elderly African American males who exhibited LAZ and had partial appositional angle closure persisting after laser iridotomy were imaged with high-resolution ultrasonography to examine for...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e31815c3b04
更新日期：2008-08-01 00:00:00
abstract：PURPOSE:To report a case of Ahmed glaucoma valve-induced hypotony that was successfully managed with postoperative intraluminal stenting of the aqueous shunt tube. PATIENT AND METHODS:We describe a 68-year-old man with advanced uveitic glaucoma with an intraocular pressure (IOP) of 25 mm Hg in the left eye. The patien...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000869
更新日期：2018-03-01 00:00:00
abstract：INTRODUCTION:We present a case of persistent aqueous misdirection, after Ahmed glaucoma valve surgery, despite undergoing an anterior vitrectomy with hyaloido-zonulectomy and iridectomy. CASE REPORT:A 73-year-old female patient, 4 months after phacotrabeculectomy, was referred with persistent high intraocular pressure...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000877
更新日期：2018-04-01 00:00:00
abstract：PURPOSE:Our purpose was to evaluate the clinical outcomes of the Ex-PRESS miniature glaucoma device placed under a partial-thickness scleral flap as a single procedure or combined with phacoemulsification cataract surgery. METHODS:This was a comparative consecutive case series of 345 eyes: 231 eyes treated with Ex-PRE...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e31818fb44e
更新日期：2009-08-01 00:00:00
abstract：PURPOSE:The purpose of this article was to report the efficacy of intravitreal bevacizumab to resolve secondary angle-closure glaucoma caused by biliary tract carcinoma metastasis to the iris. MATERIALS AND METHODS:A 52-year-old white woman who was under systemic chemotherapy for biliary tract carcinoma presented with...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000959
更新日期：2018-06-01 00:00:00
abstract：PURPOSE:To examine the reproducibility of the new digital Goldmann applanation tonometer AT 900D (DGT) for measuring intraocular pressure and to compare its readings with those provided by the conventional analog Goldmann tonometer (AGT). METHODS:In 3 different sessions (S1, S2, and S3), 3 intraocular pressure measure...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e31820bd1e9
更新日期：2012-03-01 00:00:00
abstract：PURPOSE:To evaluate strength of associations between optical coherence tomography (OCT)-angiography vessel density (VD) measurements in the macula and peripapillary region of the optic nerve head (ONH) with standard structural OCT thickness measures. MATERIALS AND METHODS:This cross-sectional study included 333 eyes o...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0000000000000862
更新日期：2018-03-01 00:00:00
abstract：PURPOSE:To study the relationship between optic disc hemorrhages and four different groups of medications used in general vascular disease and diabetes. METHODS:The authors screened citizens of the city of Malmö, Sweden who were between 57 and 79 years old (32,918 subjects), in order to find individuals with undetecte...
journal_title：Journal of glaucoma
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1097/00061198-200206000-00011
更新日期：2002-06-01 00:00:00
abstract：PURPOSE:To determine if a new, normative, race-specific database enhances the ability of confocal scanning laser ophthalmoscopy to differentiate normal from glaucomatous eyes. METHODS:One eye of eligible normal and glaucoma patients was enrolled. All subjects underwent a complete ophthalmologic examination, standard a...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/01.ijg.0000212289.00917.a8
更新日期：2006-12-01 00:00:00
abstract：PURPOSE:To evaluate the reproducibility of retinal nerve fiber layer (RNFL) thickness measurements in normal and glaucoma patients using the spectral optical coherence tomography (OCT)/scanning laser ophthalmosope (SLO). METHODS:One experienced operator measured peripapillary RNFL thickness 3 times in succession in 98...
journal_title：Journal of glaucoma
pub_type： 杂志文章
doi：10.1097/IJG.0b013e3181ca7cbe
更新日期：2010-12-01 00:00:00
