Dual occurrence of pineal germinoma and testicular seminoma. Case report and review of the literature.

Abstract:

:A 16-year-old male presented with obstructive hydrocephalus secondary to pineal germinoma. There have been many reported cases of abdominal metastasis of pineal germinoma after ventriculoperitoneal shunting. Endoscopic ventriculostomy was preferred in our case, thus avoiding iatrogenic peritoneal seeding, but spinal metastasis was unavoidable. Metastatic infiltration of the ventricular system and spinal meninges is the commonest mode of spread. Later, the patient underwent orchidectomy for an asymptomatic left testicular seminoma. He responded to chemotherapy, and had a complete recurrence-free remission for more than 10 years. As far as we know there are only a handful of reported cases of dual occurrence of two primary germ cell tumors (GCT), i.e. gonadal seminoma and pineal germinoma with spinal seeding. We also addressed the controversial subject of radiation versus chemotherapy in the management of patients with pineal germinomas. A review of the relevant literature and recommendations for future treatment of similar cases are discussed.

journal_name

Pediatr Neurosurg

journal_title

Pediatric neurosurgery

authors

Ho CL,Deruytter MJ

doi

10.1159/000089508

keywords:

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

38-44

issue

1

eissn

1016-2291

issn

1423-0305

pii

89508

journal_volume

42

pub_type

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