Brainstem gliomas in children. A Children's Cancer Group review of 119 cases.

Abstract:

:Brainstem gliomas (BSG) with intrinsic and extensive brainstem involvement continue to have a poor outlook despite current treatment approaches. Neuroimaging studies have aided in the differentiation of malignant brainstem tumors from more 'benign' subgroups. A Children's Cancer Group protocol evaluating outcome in children with BSG after treatment with hyperfractionated radiotherapy (7,200-7,800 cGy) was recently completed. The clinical aspects of 119 children entered into this study were reviewed in an attempt to determine risk groups and prognostic indicators. The overall survival of this group was very poor and there was no statistically significant correlation of survival with age, sex, clinical symptoms and signs, or tumor grade. Longer survival was only associated with prolonged duration of brainstem symptoms and signs greater than 1 month prior to diagnosis of the tumor. Improved outlook for children with BSG will require further research in tumor biology and newer therapeutic modalities.

journal_name

Pediatr Neurosurg

journal_title

Pediatric neurosurgery

authors

Kaplan AM,Albright AL,Zimmerman RA,Rorke LB,Li H,Boyett JM,Finlay JL,Wara WM,Packer RJ

doi

10.1159/000121036

subject

Has Abstract

pub_date

1996-01-01 00:00:00

pages

185-92

issue

4

eissn

1016-2291

issn

1423-0305

journal_volume

24

pub_type

杂志文章
  • Three choroid plexus papillomas in a patient with Aicardi syndrome. A case report.

    abstract::Aicardi syndrome is an X-linked dominant disorder primarily defined by the triad of corpus callosum agenesis, infantile spasms and a pathognomonic lacunar chorioretinopathy. Papillomas of the choroid plexus have been reported in affected patients. We report an Aicardi syndrome patient who had three separate choroid pl...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章,评审

    doi:10.1159/000055956

    authors: Taggard DA,Menezes AH

    更新日期:2000-10-01 00:00:00

  • Arachnoid cyst rupture with concurrent subdural hygroma.

    abstract::Arachnoid cysts (ACs) are relatively common intracranial mass lesions, which occur most often in the middle cranial fossa. While these lesions can present as a mass lesion, many are asymptomatic. Rarely, posttraumatic or spontaneous rupture of ACs can result in intracystic hemorrhage, subdural hematoma or subdural hyg...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000028918

    authors: Donaldson JW,Edwards-Brown M,Luerssen TG

    更新日期:2000-03-01 00:00:00

  • Are dermoid and epidermoid tumors preventable complications of myelomeningocele repair?

    abstract::Dermoids and epidermoids found at reoperation for tethered cord following myelomeningocele repair have been attributed to inadequate excision of cutaneous elements and 'implantation' in the repair site. This study reviews the pathological findings in excised placodes from fresh myelomeningoceles and specimens from tet...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章,评审

    doi:10.1159/000120780

    authors: Storrs BB

    更新日期:1994-01-01 00:00:00

  • Cerebral sparganosis in a child.

    abstract::Cerebral sparganosis in childhood is very rare. Until 1996, 2 cases in children up to 15 years of age had been described. We report a case of cerebral sparganosis in a 6-year-old girl who presented with seizures. Sequential brain magnetic resonance imaging scans spaced over 4 months showed a lesion which migrated from...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章,评审

    doi:10.1159/000121171

    authors: Kim CY,Cho BK,Kim IO,Hwang YS,Wang KC

    更新日期:1997-02-01 00:00:00

  • Pediatric brain tumors in a 10-year period from 1986 to 1995 in Yamaguchi prefecture: epidemiology and comparison with adult brain tumors.

    abstract::The epidemiology of pediatric brain tumor was studied in a 10-year period from 1986 to 1995 in Yamaguchi prefecture. The total number of pediatric brain tumors was 83, and the incidence was 2.5/100, 000/year, which did not change during the period. The sign most frequently seen was intracranial hypertension, whereas f...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000028636

    authors: Nomura S,Nishizaki T,Yamashita K,Ito H

    更新日期:1998-03-01 00:00:00

  • Traumatic Pediatric Posterior Fossa Extradural Hematomas: A Tertiary-Care Trauma Center Experience from India.

    abstract:INTRODUCTION:Traumatic posterior fossa extradural hematomas (PFEDH) are rare lesions constituting <10% of all extradural hematomas. Reliance on clinical findings alone is not recommended as these are nonspecific; for all suspicious cases, it is advisable to conduct a CT scan. Only a handful of pediatric studies have be...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000438488

    authors: Prasad GL,Gupta DK,Sharma BS,Mahapatra AK

    更新日期:2015-01-01 00:00:00

  • Intracranial nasal dermoid sinus cyst associated with colloid cyst of the third ventricle. Case report and new concepts.

    abstract::A case of a 16-year-old male with both a nasal dermoid sinus cyst (NDSC) and a third ventricle colloid cyst is presented. The NDSC was excised via a single-stage combined intracranial-extracranial approach and the third ventricle colloid cyst was resected endoscopically. The pathogenetic theories of NDSC and third ven...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000028862

    authors: Cheng ML,Chang SD,Pang D,Adler JR

    更新日期:1999-10-01 00:00:00

  • Do grip and pinch strength predict neurologic complications in children with spina bifida and hydrocephalus?

    abstract:BACKGROUND:Neurological complications occur commonly in children with meningomyelocele and can cause significant morbidity and mortality. An earlier study suggested that acute changes in grip and pinch strength could be used to identify individuals at increased risk for developing a neurological complication. OBJECTIV...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000092356

    authors: Liptak GS,Fried R,Baltus-Hebert E,Eyer Tierney S,Fucile S,Doremus TL

    更新日期:2006-01-01 00:00:00

  • Pediatric skull base surgery. 1. Embryology and developmental anatomy.

    abstract::Surgical pathology of the pediatric cranial base is uncommon, but in affected children, traditional operative techniques and management philosophies predominate. While the creation of multidisciplinary skull base teams synergistically pools the talents of individual specialties, a better understanding of the developme...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章,评审

    doi:10.1159/000067558

    authors: Gruber DP,Brockmeyer D

    更新日期:2003-01-01 00:00:00

  • The perception of complications in pediatric spine surgery: a comparative survey of surgeons, caregivers and patients.

    abstract:BACKGROUND/AIMS:The perception of a surgical complication may differ between surgeons and patients. In pediatric spine surgery, the perception of the parent or primary caregiver may also differ. In order to better define these relationships, we performed a pilot study surveying a convenience sample of pediatric spinal ...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000319364

    authors: Fulkerson DH,Vachhrajani S,Brayton A,Kulkarni AV,Jea A

    更新日期:2010-01-01 00:00:00

  • An unusual case of traumatic intracranial hemorrhage caused by wakeboarding.

    abstract::Wakeboarding is a relatively new and exciting sporting activity which is similar to water-skiing. While there have been several reports of water-skiing-related injuries, there has been nothing reported in the literature so far concerning injuries in wakeboarding. We present the case of a 14-year-old male who sustained...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000028957

    authors: Chia JK,Goh KY,Chan C

    更新日期:2000-06-01 00:00:00

  • Experimental split cord malformations.

    abstract:OBJECTIVE:To induce experimental split cord malformations (SCMs) produced through the surgical induction of a dorsal midline fistula. METHODS:In addition, the theory of embryogenesis of SCMs was verified by examining the developmental process of this experimentally induced anomaly. In Cynopus pyrrhogaster (amphibian) ...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000058425

    authors: Emura T,Asashima M,Furue M,Hashizume K

    更新日期:2002-05-01 00:00:00

  • Diagnosis and management of the Dandy-Walker malformation: 30 years of experience.

    abstract::Thirty-seven patients with Dandy-Walker malformation were treated between 1959 and 1989. Eighty percent of patients became symptomatic by 3 years of age, with 70% presenting within the 1st year of life. Hydrocephalus was present in 91% of patients at the time of diagnosis. Clinical presentation was most often heralded...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000120660

    authors: Osenbach RK,Menezes AH

    更新日期:1992-01-01 00:00:00

  • Towards development of a survival prediction tool for pediatric head injury.

    abstract:BACKGROUND:The ability to provide an accurate prognosis for children with traumatic brain injury (TBI) would be useful for the children's families and the caregivers. In this study we examined whether an appropriate mathematical model can predict survival in this patient population. METHODS:Data from the Children's Ho...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000340068

    authors: Kouznetsov E,Brennan M,Vassilyadi M

    更新日期:2012-01-01 00:00:00

  • Transient Anton's syndrome: a presenting feature of acute epidural hematoma at the confluens sinuum.

    abstract::Although unilateral epidural hematomas are well known, bilateral presentation, especially at the confluens sinuum, is uncommon, and its diagnosis may be delayed, thus causing morbidity. We report a case of acute posttraumatic cortical blindness due to epidural hematoma at the confluens sinuum caused by venous sinus te...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000068813

    authors: Yilmazlar S,Taskapilioglu O,Aksoy K

    更新日期:2003-03-01 00:00:00

  • Adenovirus encephalitis and widespread ependymitis in a child with AIDS.

    abstract::A 4-year-old child with AIDS developed encephalitis 2 months prior to death. Adenovirus was cultured from the cerebrospinal fluid. At autopsy, sections of the brain revealed complete sloughing of the intracranial ependyma, with marked gliosis and edema of the periventricular white matter. Cells with large, dark, smudg...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000120551

    authors: Anders KH,Park CS,Cornford ME,Vinters HV

    更新日期:1990-01-01 00:00:00

  • The early years of hemispherectomy.

    abstract::Today, hemispherectomy is a well-established procedure for the treatment of some sorts of catastrophic epilepsies. This, however, has not always been the case. The technique was developed to deal with brain tumors; however, the initial results were not remarkable. Moreover, when its morbidity became evident, it was al...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章,评审

    doi:10.1159/000085870

    authors: de Almeida AN,Marino R Jr

    更新日期:2005-05-01 00:00:00

  • Endoscopic biopsy for tumors of the third ventricle.

    abstract::Twelve patients underwent endoscopic biopsy of a tumor involving the third ventricle. Nine patients had no significant medical history while 3 had a history of cancer. Unique characteristics of each case dictated the optimal surgical technique. Endoscopic tumor biopsy was combined with additional procedures in 9 cases...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000028994

    authors: Souweidane MM,Sandberg DI,Bilsky MH,Gutin PH

    更新日期:2000-09-01 00:00:00

  • Ascending transaqueductal cystoventriculoperitoneal shunting in Dandy-Walker malformation: technical note.

    abstract::The optimal treatment for Dandy-Walker malformation is still controversial. Ventriculoperitoneal shunting, cystoperitoneal shunting or combinations are the most common surgical options in the management of this clinical entity. Endoscopic procedures like ventriculocystostomy, 3rd ventriculostomy or endoscopy-assisted ...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000353610

    authors: Unal OF,Aras Y,Aydoseli A,Akcakaya MO

    更新日期:2012-01-01 00:00:00

  • Peculiarities and Patterns of Cervical Spine Injuries in Children and Adolescents: A Retrospective Series of 84 Patients from a Single Institute.

    abstract::Cervical spine injuries occur infrequently in children but are associated with significant disability and mortality. A retrospective analysis was performed of 84 consecutive pediatric spine injuries treated at our institute from January 2002 to December 2011. The mean age was 14.7 years. There were 18 patients (21%) i...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000439540

    authors: Babu RA,Arivazhagan A,Devi BI,Bhat DI,Sampath S,Chandramouli BA

    更新日期:2016-01-01 00:00:00

  • Rare Infratentorial and Supratentorial Localization of Juvenile Angiofibroma: A Case Report.

    abstract::Angiofibromas are rare tumors of the head and neck that mostly occur in the sphenopalatine region. We present a case of angiofibroma in a young male patient with an unusual and extremely rare localization, which to our knowledge has not been described before. It was situated in the tentorium and spread to the supraten...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000448051

    authors: Pašalić I,Trninić I,Nemir J,Jednačak H,Žarković K,Mrak G

    更新日期:2016-01-01 00:00:00

  • Fibrous dysplasia of the skull in children.

    abstract::Early diagnosis of skull fibrous dysplasia in children is relatively easy, based on a history of painless progressive bony bulging. The therapeutic approach is still controversial, due to the benignity of the lesion. However, the clinical course may be unpredictable, with sudden appearance of symptoms, some of which c...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000120649

    authors: Di Rocco C,Marchese E,Velardi F

    更新日期:1992-01-01 00:00:00

  • Dynamic Changes in Arteriovenous Malformations (AVMs): Spontaneous Growth and Resolution of AVM-Associated Aneurysms in Two Pediatric Patients.

    abstract::Arteriovenous malformations (AVMs) of the central nervous system are dynamic lesions that can change with time. One of the most clinically important concerns is the development and potential rupture of AVM-associated aneurysms. In this report, we review pediatric cases of de novo development of AVM-associated aneurysm...

    journal_title:Pediatric neurosurgery

    pub_type:

    doi:10.1159/000501041

    authors: Koch MJ,Mahal BAV,Hadzipasic M,Fehnel KP,Chapman PH,Loeffler JS,Orbach DB,Smith ER

    更新日期:2019-01-01 00:00:00

  • Utility of clinical and radiographic findings in the management of traumatic epidural hematoma.

    abstract:BACKGROUND:There are currently no clear guidelines for the management and radiological monitoring of pediatric patients with epidural hematomas (EDH). We aim to compare clinical and radiographic characteristics of pediatric EDH patients managed with observation alone versus surgical evacuation and to describe results o...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000363143

    authors: Flaherty BF,Loya J,Alexander MD,Pandit R,Ha BY,Torres RA,Schroeder AR

    更新日期:2013-01-01 00:00:00

  • Fully endoscopic supraorbital resection of congenital middle cranial fossa arachnoid cysts: report of 2 cases.

    abstract::Intracranial congenital arachnoid cysts are benign intra-arachnoidal fluid collections with a wall composed of arachnoid cells encompassing a cavity containing a fluid similar to cerebrospinal fluid. This cavity frequently communicates with the subarachnoid space. Arachnoid cysts are reported to account for about 1% o...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000103314

    authors: Kabil MS,Shahinian HK

    更新日期:2007-01-01 00:00:00

  • Electroencephalography features of primary epileptogenic regions in surgically treated MRI-negative infantile spasms.

    abstract:OBJECTIVE:To evaluate the surgical outcome for intractable, MRI-negative infantile spasms (IS), and to identify diagnostic targets in the focal epileptogenic area by methods other than MRI. METHODS:We retrospectively studied 9 patients who had had surgery for intractable IS, and whose lesions did not appear on MRI. We...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000321925

    authors: Hur YJ,Lee JS,Kim DS,Hwang T,Kim HD

    更新日期:2010-01-01 00:00:00

  • Gastric perforation due to ventriculo-peritoneal shunt.

    abstract::Gastric perforation is a complication that can arise from ventriculo-peritoneal (VP) shunting. Careful examination of a newborn girl admitted to our department revealed several neurological problems. A VP shunt was inserted under direct visualization, leaving 20 cm of the catheter in the peritoneal cavity. The infant ...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000120834

    authors: Alonso-Vanegas M,Alvarez JL,Delgado L,Mendizabal R,Jiménez JL,Sanchez-Cabrera JM

    更新日期:1994-01-01 00:00:00

  • Stereotactic radiosurgery in children and adolescents.

    abstract::Stereotactic radiosurgery has had an increasing role in the treatment of selected intracranial lesions in pediatric patients. In our first 44 months experience, 60 of the patients (9%) treated were less than or equal to 18 years of age. Current indications for radiosurgery include primary treatment of high-risk arteri...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000120530

    authors: Kondziolka D,Lunsford LD,Flickinger JC

    更新日期:1990-01-01 00:00:00

  • The Total Calvarial Remodeling with Transsutural Distraction Osteogenesis of 21 Cases of Craniosynostosis: New, Efficient, Safe and Natural Method in Craniosynostosis Surgery.

    abstract:INTRODUCTION:The majority of the present distraction osteogenesis techniques involve local site expansion that only produces localized decompression and affords limited decompression and cosmetic results. We designed a new surgical procedure, total calvarial transsutural distraction osteogenesis (TSuDO). METHODS:We pe...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000381860

    authors: Park DH,Yoon SH

    更新日期:2015-01-01 00:00:00

  • Cytogenetic studies of pediatric brain and spinal cord tumors.

    abstract::Seventy pediatric patients with brain and spinal cord tumors had cytogenetic analysis of 99 samples of their tumors. Successful analysis was accomplished in 95%. Tumors included 43 gliomas, 9 medulloblastomas and a variety of other lesions. Forty-three patients had normal chromosomes; 28 of these had benign tumors and...

    journal_title:Pediatric neurosurgery

    pub_type: 杂志文章

    doi:10.1159/000120569

    authors: Chadduck WM,Boop FA,Sawyer JR

    更新日期:1991-01-01 00:00:00