Adenovirus encephalitis and widespread ependymitis in a child with AIDS.

Abstract:

:A 4-year-old child with AIDS developed encephalitis 2 months prior to death. Adenovirus was cultured from the cerebrospinal fluid. At autopsy, sections of the brain revealed complete sloughing of the intracranial ependyma, with marked gliosis and edema of the periventricular white matter. Cells with large, dark, smudgy intranuclear inclusions, consistent with adenovirus inclusions, were also seen in subependymal locations. In situ hybridization studies confirmed the presence of adenovirus DNA in these cells. This represents a case of morphologically proven adenovirus encephalitis in a pediatric AIDS patient.

journal_name

Pediatr Neurosurg

journal_title

Pediatric neurosurgery

authors

Anders KH,Park CS,Cornford ME,Vinters HV

doi

10.1159/000120551

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

316-20

issue

6

eissn

1016-2291

issn

1423-0305

journal_volume

16

pub_type

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