Chromosomal fragmentation is the major consequence of the rdgB defect in Escherichia coli.

Abstract:

:The rdgB mutants depend on recombinational repair of double-strand breaks. To assess other consequences of rdgB inactivation in Escherichia coli, we isolated RdgB-dependent mutants. All transposon inserts making cells dependent on RdgB inactivate genes of double-strand break repair, indicating that chromosomal fragmentation is the major consequence of RdgB inactivation.

journal_name

Genetics

journal_title

Genetics

authors

Lukas L,Kuzminov A

doi

10.1534/genetics.105.051144

keywords:

subject

Has Abstract

pub_date

2006-02-01 00:00:00

pages

1359-62

issue

2

eissn

0016-6731

issn

1943-2631

pii

genetics.105.051144

journal_volume

172

pub_type

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