Myomectomy for fertility enhancement and preservation.

Abstract:

OBJECTIVE:To review, evaluate, and synthesize current published reports assessing the value of abdominal myomectomy in infertile women and those desiring to preserve fertility potential. DATA IDENTIFICATION:Major studies dealing with myomectomy were identified through Medline Searches. STUDY SELECTION:Those papers reporting the results of myomectomy, factors influencing them, and potential future innovations were obtained. RESULTS:More than half of women not previously pregnant and undergoing myomectomy to preserve childbearing capacity for treatment of recurrent pregnancy wastage or previous infertility conceive. The long duration of infertility before surgery, absence of other factors to explain their not conceiving, and short time interval subsequent to surgery in which conception occurs suggests myomectomy has value in treatment of patients with leiomyomata and otherwise unexplained infertility. The operation carries acceptable risk. Approximately 25% of women undergoing myomectomy have recurrent leiomyomata, but most recurrences are sufficiently delayed to allow adequate opportunity for conception. CONCLUSIONS:Abdominal myomectomy is an appropriate alternative to hysterectomy for most women who wish to preserve childbearing potential or enhance it. For the future, myomectomy by endoscopic techniques may hold similar potential.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Verkauf BS

doi

10.1016/s0015-0282(16)55128-0

keywords:

subject

Has Abstract

pub_date

1992-07-01 00:00:00

pages

1-15

issue

1

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(16)55128-0

journal_volume

58

pub_type

杂志文章,评审
  • Outcome of hysteroscopic resection of submucous myomas for infertility.

    abstract:OBJECTIVE:To examine the reproductive outcome after operative hysteroscopic resection of submucous myomas in women for whom no other infertility factor was identified. DESIGN:Fifteen infertile women with submucous myomas underwent an intensive workup to exclude other causes of infertility. Operative hysteroscopy for r...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)57844-3

    authors: Goldenberg M,Sivan E,Sharabi Z,Bider D,Rabinovici J,Seidman DS

    更新日期:1995-10-01 00:00:00

  • Measurement of the ovarian follicle by ultrasound in ovulation induction.

    abstract::Ultrasonic monitoring of ovarian follicles and estimation of serum estradiol were carried out in 12 patients with clomiphene therapy, in 5 patients with gonadotropin therapy, and in 7 normal controls. The average diameter of preovulatory follicles in normal controls was 12,8 mm; in ovulation induction groups it was 2 ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)44055-0

    authors: Ylöstalo P,Rönnberg L,Jouppila P

    更新日期:1979-06-01 00:00:00

  • Advanced surgical sperm recovery is a viable option for intracytoplasmic sperm injection in patients with obstructive or nonobstructive azoospermia.

    abstract:OBJECTIVE:To determine whether advanced sperm retrieval is appropriate in cases of obstructive and nonobstructive azoospermia. DESIGN:Prospective controlled study. SETTING:Tertiary care center. PATIENT(S):Men with obstructive and nonobstructive azoospermia, and their partners. INTERVENTION(S):Surgical sperm retriev...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(99)00298-8

    authors: Jaroudi K,Coskun S,Hollanders J,Al-Hassan S,Al-Sufayan H,Atared A,Merdad T

    更新日期:1999-09-01 00:00:00

  • Fertilization after standard in vitro fertilization versus intracytoplasmic sperm injection in subfertile males using sibling oocytes.

    abstract:OBJECTIVE:To compare conventional IVF with ICSI in the subfertile male population using sibling oocytes. Results from males with isolated severe teratozoospermia also are analyzed. DESIGN:Prospective experimental study. SETTING:University based IVF clinic. PATIENT(S):Group A: 18 patients with one or more abnormaliti...

    journal_title:Fertility and sterility

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0015-0282(98)00538-x

    authors: Pisarska MD,Casson PR,Cisneros PL,Lamb DJ,Lipshultz LI,Buster JE,Carson SA

    更新日期:1999-04-01 00:00:00

  • Hepatic lipase activity during oral and parenteral 17 beta-estradiol replacement therapy: high-density lipoprotein increase may not be antiatherogenic.

    abstract:OBJECTIVE:Hepatic lipase activity is involved in the removal of cholesterol and phospholipid from plasma high-density lipoprotein (HDL) to the liver. Changes in hepatic lipase are responsible for some lipoprotein modifications observed during estrogen administration (i.e., increased HDL levels). The aim of this study w...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)54361-1

    authors: Basdevant A,de Lignieres B,Simon P,Blache D,Ponsin G,Guy-Grand B

    更新日期:1991-06-01 00:00:00

  • Luteal start vaginal micronized progesterone improves pregnancy success in women with recurrent pregnancy loss.

    abstract:OBJECTIVE:To assess the effectiveness of luteal start vaginal micronized P in a recurrent pregnancy loss (RPL) cohort. DESIGN:Observational cohort study using prospectively collected data. SETTING:Not applicable. PATIENT(S):Women seen between 2004 and 2012 with a history of two or more unexplained pregnancy losses <...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2016.11.029

    authors: Stephenson MD,McQueen D,Winter M,Kliman HJ

    更新日期:2017-03-01 00:00:00

  • Association study of AMH and AMHRII polymorphisms with unexplained infertility.

    abstract:OBJECTIVE:To investigate the association of AMH and AMHRII polymorphisms with reproductive abilities in a sample of women with idiopathic infertility. DESIGN:Case-control study. SETTING:University Department of Obstetrics and Gynecology, and University Unit of Clinical Genetics. PATIENT(S):76 women with idiopathic s...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2009.05.025

    authors: Rigon C,Andrisani A,Forzan M,D'Antona D,Bruson A,Cosmi E,Ambrosini G,Tiboni GM,Clementi M

    更新日期:2010-09-01 00:00:00

  • Embryo implantation in in vitro fertilization and intracytoplasmic sperm injection: impact of cleavage status, morphology grade, and number of embryos transferred.

    abstract:OBJECTIVE:The aims of this study were to compare preimplantation embryo quality in intracytoplasmic sperm injection (ICSI) with standard IVF and to examine the impact of age and number and quality of embryos transferred on implantation and pregnancy. DESIGN:Retrospective, controlled clinical study. SETTING:Academic t...

    journal_title:Fertility and sterility

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0015-0282(99)00320-9

    authors: Hsu MI,Mayer J,Aronshon M,Lanzendorf S,Muasher S,Kolm P,Oehninger S

    更新日期:1999-10-01 00:00:00

  • An analysis of fluid loss during transcervical resection of submucous myomas.

    abstract:OBJECTIVE:To determine the contribution of several variables to fluid loss during transcervical resection of submucous myomas. DESIGN:An observational study using multiple linear regression analyses. SETTING:A university-affiliated training hospital and a university department of clinical epidemiology and biostatisti...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(97)00335-x

    authors: Emanuel MH,Hart A,Wamsteker K,Lammes F

    更新日期:1997-11-01 00:00:00

  • Epidermal growth factor promotes stromal cells migration and invasion via up-regulation of hyaluronate synthase 2 and hyaluronan in endometriosis.

    abstract:OBJECTIVE:To investigate the role(s) of hyaluronan synthase 2 (HAS2) and hyaluronan in disease progression of endometriosis and epidermal growth factor (EGF)-induced motility changes of endometriotic cells. DESIGN:A case-control experimental study and in vitro primary cell culture study. SETTING:University hospital-a...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2020.05.005

    authors: Zhan H,Peng B,Ma J,Lin K,Xu K,Lin J,Yong PJ,Leung PCK,Bedaiwy MA,Lin J

    更新日期:2020-10-01 00:00:00

  • Effect of paramethasone acetate upon estrogen action.

    abstract::To test the antiestrogenic action of paramethasone acetate (PA), a group of five postmenopausal women were treated in two ways. For phase I, PA + mestranol, 6 mg + 80 micrograms per day for 10 days, was administered. Ten days were allowed for withdrawal of medication. For phase II, mestranol, 80 micrograms per day for...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:

    authors: Cortés-Gallegos V,Carranco A,Sojo I,Alonso R,Valenzuela-Duriet P

    更新日期:1982-03-01 00:00:00

  • High rate of mixoploidy among human blastocysts cultured in vitro.

    abstract:OBJECTIVE:To determine the incidence and type of mixoploidy in human blastocysts produced in vitro. DESIGN:A laboratory study of spare blastocysts from an IVF program. SETTING:University hospital laboratory. PATIENT(S):Thirty-nine couples undergoing IVF or intracytoplasmic sperm injection. INTERVENTION(S):A total o...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(02)04393-5

    authors: Bielanska M,Tan SL,Ao A

    更新日期:2002-12-01 00:00:00

  • Accuracy of hysterosalpingography and laparoscopic hydrotubation in diagnosis of tubal patency.

    abstract:OBJECTIVE:To compare the diagnostic accuracy of two methods of assessment of tubal patency, viz, hysterosalpingography (HSG) and laparoscopic hydrotubation. DESIGN:One hundred four infertile women who were investigated with both HSG and laparoscopy in King Khalid University Hospital were selected for the study. Comple...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)57540-2

    authors: Adelusi B,al-Nuaim L,Makanjuola D,Khashoggi T,Chowdhury N,Kangave D

    更新日期:1995-05-01 00:00:00

  • Brown oocytes: implications for assisted reproductive technology.

    abstract::Fertilization, embryo development, and successful pregnancy can be achieved after transfer of embryos derived from brown oocytes at the same rate as embryos from morphologically normal oocytes. Therefore, brown oocytes are probably normal and this morphological criterion does not seem to be indicative of any adverse o...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2006.03.056

    authors: Esfandiari N,Burjaq H,Gotlieb L,Casper RF

    更新日期:2006-11-01 00:00:00

  • Role of blood and fibrinogen in development of intraperitoneal adhesions in rats.

    abstract::One hundred and twenty rats were divided into six groups and laparotomized. In three of the groups the cecum was left intact. In one of these groups the cecum was only lifted up through the abdominal incision and then replaced in the abdominal cavity. In another group the intact cecum was bathed with a certain amount ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)43584-3

    authors: Nisell H,Larsson B

    更新日期:1978-10-01 00:00:00

  • A prospective evaluation of uterine abnormalities by saline infusion sonohysterography in 1,009 women with infertility or abnormal uterine bleeding.

    abstract:OBJECTIVE:To evaluate the role of saline infusion sonohysterography (SIS) in the investigation of uterine abnormalities and malformations in patients referred for infertility work-up compared with women with abnormal uterine bleeding (AUB). DESIGN:Prospective cohort study. SETTING:Academically oriented private practi...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2006.05.044

    authors: Tur-Kaspa I,Gal M,Hartman M,Hartman J,Hartman A

    更新日期:2006-12-01 00:00:00

  • Comparison of live-birth defects after luteal-phase ovarian stimulation vs. conventional ovarian stimulation for in vitro fertilization and vitrified embryo transfer cycles.

    abstract:OBJECTIVE:To assess live-birth defects after a luteal-phase ovarian-stimulation regimen (LPS) for in vitro fertilization (IVF) and vitrified embryo transfer (ET) cycles. DESIGN:Retrospective cohort study. SETTING:Tertiary-care academic medical center. PATIENT(S):Infants who were born between January 1, 2013 and May ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2015.02.020

    authors: Chen H,Wang Y,Lyu Q,Ai A,Fu Y,Tian H,Cai R,Hong Q,Chen Q,Shoham Z,Kuang Y

    更新日期:2015-05-01 00:00:00

  • Follicle-stimulating hormone receptor gene mutations are rare in Japanese women with premature ovarian failure and polycystic ovary syndrome.

    abstract:OBJECTIVE:To determine whether the known inactivating FSH receptor gene mutations are present in Japanese women with secondary amenorrhea because of premature ovarian failure (POF) and polycystic ovary syndrome (PCOS). DESIGN:Clinical and molecular studies. SETTING:An outpatient clinic in a university hospital. PATI...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(00)01673-3

    authors: Takakura K,Takebayashi K,Wang HQ,Kimura F,Kasahara K,Noda Y

    更新日期:2001-01-01 00:00:00

  • Comparison of human menopausal gonadotropin, clomiphene citrate, and combined human menopausal gonadotropin-clomiphene citrate stimulation protocols for in vitro fertilization.

    abstract::Human menopausal gonadotropins (hMG) and clomiphene citrate (CC), either alone or in combination, are frequently used for in vitro fertilization (IVF) in an attempt to maximize the number of oocytes recovered and the number of embryos transferred. However, direct comparison of the relative efficacy of these protocols ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)49889-4

    authors: Diamond MP,Hill GA,Webster BW,Herbert CM,Rogers BJ,Osteen KG,Maxson WS,Vaughn WK,Wentz AC

    更新日期:1986-12-01 00:00:00

  • Anabolic steroid-induced hypogonadism: diagnosis and treatment.

    abstract:OBJECTIVE:To develop an understanding of hypogonadal men with a history of anabolic-androgenic steroid (AAS) use and to outline recommendations for management. DESIGN:Review of published literature and expert opinions. Intended as a meta-analysis, but no quality studies met the inclusion criteria. SETTING:Not applica...

    journal_title:Fertility and sterility

    pub_type: 杂志文章,meta分析,评审

    doi:10.1016/j.fertnstert.2014.02.002

    authors: Rahnema CD,Lipshultz LI,Crosnoe LE,Kovac JR,Kim ED

    更新日期:2014-05-01 00:00:00

  • Nasal embryonic LHRH factor (NELF) mutations in patients with normosmic hypogonadotropic hypogonadism and Kallmann syndrome.

    abstract:OBJECTIVE:To determine if mutations in NELF, a gene isolated from migratory GnRH neurons, cause normosmic idiopathic hypogonadotropic hypogonadism (IHH) and Kallmann syndrome (KS). DESIGN:Molecular analysis correlated with phenotype. SETTING:Academic medical center. PATIENT(S):A total of 168 IHH/KS patients as well ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2011.01.010

    authors: Xu N,Kim HG,Bhagavath B,Cho SG,Lee JH,Ha K,Meliciani I,Wenzel W,Podolsky RH,Chorich LP,Stackhouse KA,Grove AM,Odom LN,Ozata M,Bick DP,Sherins RJ,Kim SH,Cameron RS,Layman LC

    更新日期:2011-04-01 00:00:00

  • Influence of severe endometriosis on gene expression of vascular endothelial growth factor and interleukin-6 in granulosa cells from patients undergoing controlled ovarian hyperstimulation for in vitro fertilization-embryo transfer.

    abstract:OBJECTIVE:To evaluate how endometriosis affects expression of vascular endothelial growth factor (VEGF) and interleukin-6 (IL-6) in granulosa cells. DESIGN:Prospective study. SETTING:IVF-ET program at Osaka Medical College. PATIENT(S):Seventeen patients with revised American Fertility Society stage IV endometriosis ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(02)03339-3

    authors: Yamashita Y,Ueda M,Takehara M,Yamashita H,Suzuki Y,Hung YC,Terai Y,Ueki M

    更新日期:2002-10-01 00:00:00

  • Relook hysteroscopy after antitubercular therapy.

    abstract::Hysteroscopic visualization of the endometrium after 6 months of antitubercular therapy showed an improvement in the mucosal morphology. A closer visualization at increased magnification was helpful in demonstrating the remnants of a healing tubercular pathology after antitubercular therapy. ...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2007.07.1346

    authors: Kumar A,Kumar A

    更新日期:2008-03-01 00:00:00

  • Pentoxifylline is not useful in enhancing sperm function in cases with previous in vitro fertilization failure.

    abstract:OBJECTIVE:To assess the efficiency of the addition of pentoxifylline to spermatozoa for in vitro fertilization (IVF) in cases with previous fertilization failure. DESIGN:After retrieval, oocytes were divided at random and inseminated with spermatozoa prepared with or without pentoxifylline. SETTING:In vitro fertiliza...

    journal_title:Fertility and sterility

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0015-0282(16)55641-6

    authors: Tournaye H,Janssens R,Camus M,Staessen C,Devroey P,Van Steirteghem A

    更新日期:1993-01-01 00:00:00

  • Moderate drinking: no impact on female fecundity.

    abstract:OBJECTIVE:To determine the effect of moderate alcohol intake on probability of conception. DESIGN:Prospective cohort study. SETTING:Normal healthy women enrolled in an artificial donor insemination program. PATIENTS:Women starting artificial donor insemination for the very first time were selected. INTERVENTIONS:Al...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)57056-3

    authors: Zaadstra BM,Looman CW,te Velde ER,Habbema JD,Karbaat J

    更新日期:1994-11-01 00:00:00

  • Infertility among women working in horticulture. A follow-up study in the Danish Occupational Hospitalization Register.

    abstract::The possible association between employment in horticulture with potential exposure to pesticides and female infertility was examined by identification of women with hospital contact due to infertility and working in horticulture through the Danish Occupational Hospitalization Register. This follow-up study gave a sta...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2008.04.036

    authors: Hougaard KS,Hannerz H,Feveile H,Bonde JP,Burr H

    更新日期:2009-04-01 00:00:00

  • The feasibility of assessing women's perceptions of the risks and benefits of fertility drug therapy in relation to ovarian cancer risk.

    abstract:OBJECTIVE:To determine the feasibility of asking women undergoing fertility treatment the maximum increased risk of ovarian cancer they would be willing to tolerate in order to take ovulation-induction drugs. DESIGN:A prospective pilot study of women attending fertility clinics over a 2-month period. SETTING:Two tert...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(97)81481-1

    authors: Rosen B,Irvine J,Ritvo P,Shapiro H,Stewart D,Reynolds K,Robinson G,Thomas J,Neuman J,Murphy J

    更新日期:1997-07-01 00:00:00

  • Twice-frozen embryos are no detriment to pregnancy success: a retrospective comparative study.

    abstract:OBJECTIVE:To compare the pregnancy rates (PR) and live birth rates in once- versus twice-frozen ET treatment cycles in the same cohort of women. DESIGN:A retrospective study. SETTING:Fertility clinics, IVF Australia, New South Wales. PATIENT(S):The study population was all women who underwent thawing of twice-frozen...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2011.04.034

    authors: Koch J,Costello MF,Chapman MG,Kilani S

    更新日期:2011-07-01 00:00:00

  • Exaggerated effects of progestogen on uterine artery pulsatility index in Turner's syndrome patients receiving hormone replacement therapy.

    abstract:OBJECTIVE:To investigate the effect of estrogen and progestogen on the resistance to blood flow in the uterine arteries of Turner's syndrome patients. DESIGN:Prospective clinical study. SETTING:A tertiary infertility clinic. PATIENTS:Five Turner's syndrome patients, six patients who had surgical castration, and five...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/s0015-0282(16)57968-0

    authors: Biljan MM,Taylor CT,Matijevic R,Jones SV,Garden AS,Fraser WD,Diver MJ,Kingsland CR

    更新日期:1995-12-01 00:00:00

  • Fetal Val108/158Met catechol-O-methyltransferase (COMT) polymorphism and placental COMT activity are associated with the development of preeclampsia.

    abstract:OBJECTIVE:To evaluate the association between fetal and maternal catechol-O-methyltransferase (COMT) Val158Met and methyl tetrahydrofolate reductase (MTHFR) C677T functional polymorphisms and preeclampsia, examining its influence on placental COMT and in maternal 2-methoxyestradiol (2-ME) plasma levels. DESIGN:Prospec...

    journal_title:Fertility and sterility

    pub_type: 杂志文章

    doi:10.1016/j.fertnstert.2015.09.019

    authors: Pertegal M,Fenoy FJ,Hernández M,Mendiola J,Delgado JL,Bonacasa B,Corno A,López B,Bosch V,Hernández I

    更新日期:2016-01-01 00:00:00