Anabolic steroid-induced hypogonadism: diagnosis and treatment.

Abstract:

OBJECTIVE:To develop an understanding of hypogonadal men with a history of anabolic-androgenic steroid (AAS) use and to outline recommendations for management. DESIGN:Review of published literature and expert opinions. Intended as a meta-analysis, but no quality studies met the inclusion criteria. SETTING:Not applicable. PATIENT(S):Men seeking treatment for symptomatic hypogonadism who have used nonprescribed AAS. INTERVENTION(S):History and physical examination followed by medical intervention if necessary. MAIN OUTCOME MEASURES(S):Serum testosterone and gonadotropin levels, symptoms, and fertility restoration. RESULT(S):Symptomatic hypogonadism is a potential consequence of AAS use and may depend on dose, duration, and type of AAS used. Complete endocrine and metabolic assessment should be conducted. Management strategies for anabolic steroid-associated hypogonadism (ASIH) include judicious use of testosterone replacement therapy, hCG, and selective estrogen receptor modulators. CONCLUSION(S):Although complications of AAS use are variable and patient specific, they can be successfully managed. Treatment of ASIH depends on the type and duration of AAS use. Specific details regarding a patient's AAS cycle are important in medical management.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Rahnema CD,Lipshultz LI,Crosnoe LE,Kovac JR,Kim ED

doi

10.1016/j.fertnstert.2014.02.002

subject

Has Abstract

pub_date

2014-05-01 00:00:00

pages

1271-9

issue

5

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(14)00140-X

journal_volume

101

pub_type

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