Abstract:
:This study was conducted to standardize a clinical test to assess cognitive functions in children between 3-14 years and to evaluate its use in patients with encephalopathy. We included 50 children in Group A with non-neurological illness. Another 50 children were included in Group B with encephalopathy due to varied etiologies. The Mini Mental State Examination (MMSE) used in adults was modified, using tests from standardized assessment tools previously used in Indian children. It was administered independently by two observers at admission and after a few days in the two Groups. In Group A, the mean and SD of the score in various age groups were calculated. Sensitivity and specificity of the test in predicting poor outcome with a cut-off score of 10 was calculated at admission and after a mean of 4 days. The average time taken for the test was 6.03 minutes. No significant interobserver variability was found. Cut off abnormal scores calculated as 2 SD below mean in different age groups were 3 to 5 years 24, 6 to 8 years 28, 9 to 11 years 30, 12 to 14 years 35. In children with encephalopathy a score below 10 predicted poor outcome with a sensitivity of 35 percent and specificity of 100 percent at admission. Retest after 4 days had sensitivity and specificity of 68 percent and 100 percent respectively. We conclude that the modified Child MMSE may be used as a screening test to assess and monitor cognitive functions in children.
journal_name
Indian Pediatrjournal_title
Indian pediatricsauthors
Jain M,Passi GRkeywords:
subject
Has Abstractpub_date
2005-09-01 00:00:00pages
907-12issue
9eissn
0019-6061issn
0974-7559journal_volume
42pub_type
临床试验,杂志文章abstract:Context:Infantile colic is self-limiting condition but it can be a cause of anxiety for parents and challenge for doctors. The challenge for the doctors lies in correct identification of the condition and appropriate management. The objective of this review article is to summarize the pathophysiology, treatment options...
journal_title:Indian pediatrics
pub_type: 杂志文章,评审
doi:
更新日期:2018-11-15 00:00:00
abstract::The present study was undertaken to find out the best simple anthropometric parameter for identifying low birth weight babies (LBW). A total of 1000 newborn babies were subjected to anthropometry within 48 hours of life. Birth weight was significantly correlated (p less than 0.001) with thigh circumference (TC), mid-a...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract:OBJECTIVE:To assess the Vitamin A status of pregnant women in their third trimester using maternal serum retinol levels as the indicator; and (ii) To assess the impact of postpartum Vitamin A supplementation on the Vitamin A status of exclusively breastfed infants. DESIGN:Prospective randomized single blind controlled...
journal_title:Indian pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:2000-11-01 00:00:00
abstract:OBJECTIVE:To assess the effects of delayed cord clamping (DCC) on hemoglobin (Hb), mean corpuscular volume (MCV) and ferritin level in infants 2 months or older. EVIDENCE ACQUISITION:Meta-analysis of randomized control trials searched systematically from PubMed, Cochrane and Web of science. Trials published from Jan 1...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2020-09-15 00:00:00
abstract::A study of infant feeding practices was carried out as part of a larger longitudinal study of an urban birth cohort in an area of South Delhi, India. 802 mothers of children over 1 year of age were selected randomly for interview. The study group is considered to be a representative sampling of the economic, cultura...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1976-11-01 00:00:00
abstract::We assessed the clinical response and side effects of Ferrous sulfate (FS) and Iron polymaltose complex (IPC) in 118 children with Iron deficiency anemia (IDA). Subjects were randomized to receive therapy with either oral IPC (Group A, n=59) or oral FS (Group B, n=59); all were given elemental iron in three divided do...
journal_title:Indian pediatrics
pub_type: 杂志文章,随机对照试验
doi:
更新日期:2009-10-01 00:00:00
abstract::In 2017, a 10-year-old girl, who was allegedly raped and impregnated, was denied an abortion on the basis of the Medical Termination of Pregnancy Act 1971. This perspective re-examines this issue while prioritizing the best interest of the child. We recommend that boards should be constituted at district-level hospita...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2018-10-15 00:00:00
abstract::A pilot study was undertaken to develop a feasible neonatal screening strategy for hemoglobinopathies. Isoelectric focusing using dried blood spots samples as a primary screening technique was standardized for the first time in India. The screened positives were confirmed by high performance liquid chromatography foll...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND:There is limited literature available on the phenotypic and mutation spectrum of Indian patients with Lysosomal storage disorders (LSD). OBJECTIVE:To elucidate the clinical, biochemical and mutation spectrum and to study the management options in Indian patients with lysosomal storage disorders. DESIGN:Des...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-012-0192-4
更新日期:2012-10-01 00:00:00
abstract:OBJECTIVE:To determine the clinical utility of serum neutrophil gelatinase-associated lipocalin (NGAL) as an early marker of acute kidney injury in asphyxiated neonates with hypoxic ischemic encephalopathy (HIE). DESIGN:Cohort study. SETTINGS:National Intensive Care Unit of Maternity Hospital, Ain Shams University, C...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-013-0153-6
更新日期:2013-05-08 00:00:00
abstract::This retrospective analysis documents the usefulness of fiberoptic bronchoscopy in finding the etiology of 56 cases of unresolved atelectasis in infancy, over a two year period (June 2005 to May 2007). Fiberoptic bronchoscopy identified the etiology leading to a revised diagnosis and change in management strategy in 3...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-010-0134-y
更新日期:2010-07-01 00:00:00
abstract:BACKGROUND:Neuroschistosomiasis is an uncommonly reported disease. CASE CHARACTERISTICS:An adolescent Indian boy residing in Kenya presented with headache, visual symptoms and seizures, with MRI showing space-occupying lesions in the occipital lobe and cerebellum. OBSERVATION:Brain biopsy was diagnostic of neuro-schi...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2018-11-15 00:00:00
abstract:OBJECTIVE:To evaluate the effect of clofibrate for unconjugated hyperbilirubinemia in neonates. METHODS:A systematic review with meta-analysis of randomized controlled trials or quasi-randomized controlled trials was conducted to evaluate the clofibrate treatment in neonates with unconjugated hyperbilirubinemia. We fo...
journal_title:Indian pediatrics
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s13312-012-0012-x
更新日期:2012-01-01 00:00:00
abstract::The skinfold thickness (SFT) was measured in 750 Punjabi newborns at triceps and subscapular sites using a Harpenden's Caliper. It was correlated with various maternal and neonatal factors. SFT increased with increasing gestation but showed a decline after 40 weeks. There was a positive correlation of SFT with birth w...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1991-11-01 00:00:00
abstract::Transfusion-associated graft-versus-host disease (TA-GVHD) is a dreaded complication in immunocompromized hosts. The diagnosis is often delayed because of lack of awareness and the non-specific clinical features. More than 90% patients succumb to refractory infections. The only effective preventive measure is administ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2004-12-01 00:00:00
abstract:BACKGROUND:Lipoid pneumonia is a rare form of pneumonia caused by aspiration of fatty substances. CASE CHARACTERISTICS:Acute respiratory distress syndrome in an infant due to accidental aspiration of baby oil massage. INTERVENTION:Large volume bronchoalveolar lavage. OUTCOME:Gradual recovery over a period of 5 month...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-015-0569-2
更新日期:2015-01-01 00:00:00
abstract::30 MEDLINE indexed Indian journals publishing clinical trials were identified and their editorial policies on trial registration were assessed. Trial registration number was required in 9 journals (30%).16 journals (53.33%) encouraged adherence to the CONSORT Statement, while 22 (73.33%) mentioned ICMJE Guidelines. ...
journal_title:Indian pediatrics
pub_type: 信件
doi:10.1007/s13312-013-0092-2
更新日期:2013-03-01 00:00:00
abstract::The year 2013 marks 50 years of both newborn screening and the Indian Academy of Pediatrics. India has seen a lot of change in terms of motivation, evolution and implementation of newborn screening as pilot projects for few disorders. Facilities for implementing screening using tandem mass spectrometry or what is term...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-013-0187-9
更新日期:2013-07-01 00:00:00
abstract::One hundred and seventy children of chronic seizures with strong clinical suspicion of an underlying intracranial lesion as its cause were studied by Magnetic Resonance Imaging (MRI). Maximum number of patients were between 6-12 years, males outnumbering females. Structural abnormalities were seen in 158 of the 170 pa...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1991-07-01 00:00:00
abstract::Capillaria hepatica is a very rare zoonotic infestation which primarily infests rodents and is rarely found in humans. The presenting features are fever of unknown origin, hepatomegaly and peripheral eosinophilia. Liver biopsy remains the cornerstone of diagnosis. Treatment of choice is Albendazole and outcome is gene...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2007-10-01 00:00:00
abstract::In this study, 78 middle ear aspiration samples from 59 children between the ages of 2 14 who have undergone myringotomy under general anesthesia were included. The presence of DNA genome of Chlamydia trachomatis was analyzed with polymerase chain reaction in the aspiration material. The relationship between the natur...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2005-07-01 00:00:00
abstract::Fluconazole has been used as prophylaxis against systemic fungal infections in preterm neonates. We conducted a study to determine whether cessation of a policy of prophylactic fluconazole results in a resurgence of fungal infections in a unit. Neonates born in the 3 epoches: A 36-month pre-Fluconazole prophylaxis epo...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2005-12-01 00:00:00
abstract::One hundred and four cases of osteoarticular tuberculosis were studied. There were 74 boys (71.2%) and 30 girls (28.8%). The mean age at the onset of symptoms was 7.3 years, ranging from 9 months to 18 years. Seventy four cases (71%) reported 3 months after onset of symptoms. The spine was the commonest site involved ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1992-09-01 00:00:00
abstract::We report on the etiology and the short term outcome (3 month) of children with acute renal failure (ARF) at a tertiary care centre in north India. Acute tubular necrosis was the commonest cause of ARF (33%) especially in children <5 years of age; while in children >10 years, glomerulonephritis was the commonest cause...
journal_title:Indian pediatrics
pub_type: 信件
doi:
更新日期:2011-06-01 00:00:00
abstract::The morbidity pattern and nutritional profile was evaluated of school children who resided around Mosaboni Copper Mines and in surrounding villages of Ghatsila subdivision in Singhbhum district of Bihar State, India. A total of 1424 school children (816 boys and 608 girls) between 5-17 years old were studied. Children...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1989-06-01 00:00:00
abstract:OBJECTIVES:To develop age and gender specific waist circumference references for urban Indian children aged 3 -16 years. DESIGN:Cross-sectional study. SETTING:Urban preschools and schools of Bangalore. PARTICIPANTS:9060 children (5172 boys and 3888 girls) in the age group of 3-16 years. METHODS:Weight, height, and ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-011-0126-6
更新日期:2011-10-01 00:00:00
abstract::Hepatic abscess in a neonate is a rare but serious disorder. Diagnosis of hepatic abscess requires a high index of suspicion in any septic neonate. CT scan and ultrasound of liver are the most sensitive diagnostic tests in detection of hepatic abscess. Portal vein thrombosis and portal cavernoma formation is hitherto ...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2003-10-01 00:00:00
abstract::The study was undertaken to compare the antibody response of 6-12 weeks old infants after three doses of standard trivalent oral polio vaccine (TOPV) (Groups A; (n = 42) with three doses of double the amount of TOPV (Group B; n = 35). Seroconversions in Group A were 64.2, 80.9% and 57.1% for Types I, II and III poliov...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:1991-10-01 00:00:00
abstract::Neural tube defects (NTD) comprise of a group of congenital malformations that include spina bifida, anencephaly and encephalocele. Reports have implicated zinc deficiency as one of the causative factors of NTDs. We compared the serum zinc level of 23 newborns having neural tube defects with 35 healthy controls by spe...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:
更新日期:2006-09-01 00:00:00
abstract::Madhya Pradesh has made remarkable progress in facility based management of severe acute malnutrition, and has developed a model that is being replicated in many states. India has uniquely high prevalence of both stunting and wasting, implying that both severe acute malnutrition and severe chronic malnutrition co-exis...
journal_title:Indian pediatrics
pub_type: 杂志文章
doi:10.1007/s13312-014-0341-z
更新日期:2014-02-01 00:00:00