Abstract:
:Lactadherin is a phosphatidylserine-binding glycoprotein secreted by macrophages. Less than 0.5% of normal circulating red cells showed any binding to lactadherin. However, the red cells from patients with sickle cell disease showed 2 to 10-fold increases in lactadherin binding. Further, lactadherin stimulated the phagocytosis of sickle red blood cells by macrophages suggesting a potential role in sickle red cell clearance.
journal_name
Haematologicajournal_title
Haematologicaauthors
Dasgupta SK,Thiagarajan Pkeywords:
subject
Has Abstractpub_date
2005-09-01 00:00:00pages
1267-8issue
9eissn
0390-6078issn
1592-8721journal_volume
90pub_type
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