Abstract:
PURPOSE:To investigate the efficacy of currently available correction factors in correcting intraocular pressure (IOP) measurements for the errors induced by the normal variations in corneal structural characteristics. MATERIALS AND METHODS:Central corneal thickness (CCT) and corneal radius of curvature were measured on 324 individuals (175 normal: group 1 and 149 had either open angle glaucoma or ocular hypertension: group 2). IOP was measured in all normal subjects with the Goldmann applanation tonometer and the highest recorded IOP was obtained from patient charts for subjects with either open angle glaucoma or ocular hypertension. Regression analysis was performed on IOP, CCT, and corneal radius of curvature. The corrected IOP was also calculated using the models proposed by Ehlers and Orssengo and Pye. Linear regression analysis was used to calculate the residual association between corneal parameters and corrected IOP. RESULTS:There was a significant positive correlation between IOP measured using Goldmann applanation tonometer and the CCT in both groups. There was no significant correlation between corneal radius of curvature and IOP in either group. There was a significant negative correlation in both the groups between CCT and corrected IOP calculated using the models of Ehlers and Orssengo and Pye. This indicates that the Ehlers and Orssengo and Pye models may significantly overestimate the effect of CCT on IOP measurement. CONCLUSION:The effect of CCT and IOP as observed in the present study and by other studies in literature is less than predicted by both the Ehlers formula and the Orssengo and Pye model. Correcting IOP for the effect of CCT using these models could be erroneous and lead to overcorrection of IOP, thus resulting in erroneously low corrected IOP eyes with thicker cornea and erroneously high corrected IOP in eyes with thinner cornea.
journal_name
J Glaucomajournal_title
Journal of glaucomaauthors
Gunvant P,O'Leary DJ,Baskaran M,Broadway DC,Watkins RJ,Vijaya Ldoi
10.1097/01.ijg.0000176940.81799.33keywords:
subject
Has Abstractpub_date
2005-10-01 00:00:00pages
337-43issue
5eissn
1057-0829issn
1536-481Xpii
00061198-200510000-00003journal_volume
14pub_type
杂志文章abstract:PURPOSE:Our purpose was to evaluate the clinical outcomes of the Ex-PRESS miniature glaucoma device placed under a partial-thickness scleral flap as a single procedure or combined with phacoemulsification cataract surgery. METHODS:This was a comparative consecutive case series of 345 eyes: 231 eyes treated with Ex-PRE...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e31818fb44e
更新日期:2009-08-01 00:00:00
abstract::Management of glaucoma during pregnancy represents a challenge for the physician. Important disease and patients' health decisions begin even before conception and continue throughout pregnancy and breastfeeding. The data on this topic is limited due to ethical and legal constraints and challenges of conducting large,...
journal_title:Journal of glaucoma
pub_type: 杂志文章,评审
doi:10.1097/IJG.0000000000001324
更新日期:2019-10-01 00:00:00
abstract:PURPOSE:The aim of this study was to quantitatively study the retinal nerve fiber layer (RNFL) thickness in children born prematurely with isolated optic nerve cupping. PATIENTS AND METHODS:Six otherwise healthy premature children with clinical evidence of increased cup to disc ratios were enrolled in this observation...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000006
更新日期:2014-01-01 00:00:00
abstract:PURPOSE:To evaluate the neuroprotective effect of rasagiline (N-propargyl-1 (R)-aminoindan), a selective monoamine oxidase inhibitor, on the survival of retinal ganglion cells (RGCs) in glaucomatous rat eyes. Rasagiline is an FDA approved anti-Parkinson disease drug with neuroprotective capabilities that were shown in ...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e3181e3d101
更新日期:2011-06-01 00:00:00
abstract::The most effective way to control glaucoma is by lowering intraocular pressure (IOP) in order to prevent the progression of the disease. Glaucoma drainage devices (GDDs) are surgical option reserved for refractory cases and have been designed to address known complications of conventional filtering surgery. They are, ...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000001417
更新日期:2020-02-01 00:00:00
abstract:PURPOSE:To identify the distribution, variation, and determinants of ganglion cell-inner plexiform layer (GC-IPL) thickness in healthy Turkish children measured by high-definition optical coherence tomography (HD-OCT). PATIENTS AND METHODS:This institutional study involved 296 eyes from 296 healthy children aged betwe...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000168
更新日期:2015-06-01 00:00:00
abstract::The mainstay of open-angle glaucoma surgery involves subconjunctival drainage of aqueous fluid. Insertion of the XEN Gel Stent leads to formation of a subconjunctival bleb to assist in the drainage of aqueous fluid and offers the advantage of ease and speed of insertion with conjunctival sparing over traditional surgi...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000001058
更新日期:2018-10-01 00:00:00
abstract:PURPOSE:To assess how glaucoma patients use their topical medications. METHODS:142 subjects were tested before an examiner as to how they used their eyedrops. RESULTS:Fifty-six patients (39.4%) used one drop. The number of drops instilled increased with age. The tip of the bottle touched the ocular surface in 78 (54....
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:
更新日期:1995-06-01 00:00:00
abstract:PURPOSE:The most common reason for long-term failure of glaucoma filtering surgery (GFS) is scarring of the external filtering "bleb" tissues. The identification of the factors that mediate this process, as well as the development and initial testing of new therapies to limit scarring is enhanced by the use of appropri...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/01.ijg.0000131482.86547.5a
更新日期:2004-10-01 00:00:00
abstract:PURPOSE:To investigate the amount of intraocular pressure (IOP) asymmetry in a large group of ethnically diverse patients with and without glaucoma, and to delineate the risk for glaucoma which increasing amounts of IOP asymmetry confer upon the patient. PATIENTS AND METHODS:Collaborative retrospective study of 326 gl...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e318237bfb8
更新日期:2013-03-01 00:00:00
abstract:PURPOSE:To find the dropout rate and identify the clinical characteristics of patients who drop out in the first year of follow-up from a glaucoma clinic. DESIGN:Descriptive hospital-based study at a tertiary hospital eye department. METHODS:Clinical characteristics of consecutive patients newly diagnosed with glauco...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e31815768b3
更新日期:2008-04-01 00:00:00
abstract:PURPOSE:To assess the reproducibility of retinal nerve fiber layer thickness and macular thickness measurements using OCT-3. METHODS:Randomly chosen eyes of healthy individuals were scanned following pupillary dilation by two trained operators (RGO, RV) using OCT-3 (software version A1.1, Carl Zeiss Meditec, Inc., Dub...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/00061198-200406000-00012
更新日期:2004-06-01 00:00:00
abstract:PURPOSE:The purpose of this article was to report the efficacy of intravitreal bevacizumab to resolve secondary angle-closure glaucoma caused by biliary tract carcinoma metastasis to the iris. MATERIALS AND METHODS:A 52-year-old white woman who was under systemic chemotherapy for biliary tract carcinoma presented with...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000959
更新日期:2018-06-01 00:00:00
abstract:PURPOSE:The aim of this study was to compare the peripapillary vessel density between eyes with pseudoexfoliation glaucoma (PXG) and eyes with primary open-angle glaucoma (POAG). METHODS:Peripapillary vessel density in the radial peripapillary capillaries was assessed using optical coherence tomography angiography, an...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000001062
更新日期:2018-11-01 00:00:00
abstract:OBJECTIVE:To evaluate the risk of developing glaucoma in patients taking systemic fluoroquinolones. METHODS:A case-control study was carried out among a cohort of subjects who had visited an ophthalmologist in the Province of British Columbia, Canada from 2000 to 2007. Cases were identified as those newly diagnosed wi...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e31829463c1
更新日期:2014-09-01 00:00:00
abstract:PRECIS:Repeated use of the Micropulse P3 (MP3) probe during micropulse transscleral cyclophotocoagulation is associated with an increase in laser output over time. PURPOSE:The purpose of this study was to examine the laser efficacy of the MP3 probe following repeated use. METHODS:This was an observational study carri...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000001277
更新日期:2019-08-01 00:00:00
abstract:PRECIS:Hypotony keratopathy is a potential complication of hypotony following trabeculectomy and successful treatment depends on increasing intraocular pressure (IOP). PURPOSE:To evaluate corneal decompensation in patients following trabeculectomy with adjuvant mitomycin C (MMC). We propose "hypotony keratopathy" as a...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000001425
更新日期:2020-02-01 00:00:00
abstract::PRéCIS:: Glaucomatous eyes without detectable 10-2 visual field loss showed significant macular vessel density loss, especially in inferior quadrant of perifoveal area. Macular vessel density loss spatially corresponded with structural and functional damage. PURPOSE:The purpose of this study was to investigate the ch...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000001578
更新日期:2020-10-01 00:00:00
abstract:PURPOSE:To evaluate and compare the findings and changes of the anterior chamber angle configuration with indentation ultrasound biomicroscopy (UBM) gonioscopy in relative pupillary block (RPB), peripheral anterior synechia (PAS), and plateau iris configuration (PIC). METHODS:This study included 73 eyes of 52 patients...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/01.ijg.0000141366.45974.3a
更新日期:2004-12-01 00:00:00
abstract:PURPOSE:Primary open-angle glaucoma is a significant health-economic burden in both the United States and Europe that is likely to increase. This study compared treatment patterns and cost among patients with primary open-angle glaucoma in these locations. METHODS:Retrospective medical chart reviews were conducted in ...
journal_title:Journal of glaucoma
pub_type: 杂志文章,多中心研究
doi:10.1097/IJG.0b013e3180575202
更新日期:2007-08-01 00:00:00
abstract:PURPOSE:To compare the intraocular pressure-lowering effect of unoprostone isopropyl (unoprostone) 0.12% and latanoprost 0.005%. A correlation between the intraocular pressure-lowering effect of unoprostone and latanoprost was also evaluated. METHODS:A single-masked randomized study included 18 patients between 49 and...
journal_title:Journal of glaucoma
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1097/00061198-200112000-00009
更新日期:2001-12-01 00:00:00
abstract::Elastin is the major protein of elastic fibers and is responsible for the elastic recoil. Elastic fibers are a major component of the extracellular matrix in the human lamina cribrosa and undergo marked changes in primary open-angle glaucoma. Ultrastructural and immunocytochemical analysis demonstrated fragmentation o...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:
更新日期:1994-10-01 00:00:00
abstract:PURPOSE:To describe a new and simple technique of glaucoma tube extension that carries several advantages over previously described techniques. PATIENTS AND METHODS:A retrospective noncomparative case series of 3 patients (1 adult and 2 pediatric cases) with glaucoma tube retraction managed by the "tube-in-tube" techn...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000567
更新日期:2017-02-01 00:00:00
abstract:PRECIS:Glycerin-preserved, human-donor, corneoscleral patch grafts are effective and safe for glaucoma drainage device (GDD) implantation, and they are comparable to previously reported materials. It can be preserved with the sterile technique for up to 12 months. PURPOSE:To evaluate the efficacy and safety of glyceri...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000001610
更新日期:2020-11-01 00:00:00
abstract:PURPOSE:To examine the reproducibility of the new digital Goldmann applanation tonometer AT 900D (DGT) for measuring intraocular pressure and to compare its readings with those provided by the conventional analog Goldmann tonometer (AGT). METHODS:In 3 different sessions (S1, S2, and S3), 3 intraocular pressure measure...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e31820bd1e9
更新日期:2012-03-01 00:00:00
abstract:PURPOSE:To evaluate the safety and efficacy of Ahmed Glaucoma Valve implantation (AGVI) for the management of neovascular glaucoma (NVG) associated with proliferative diabetic retinopathy (PDR) in the vitrectomized eyes. PATIENTS AND METHODS:We reviewed the medical records of patients with NVG associated with PDR who ...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e3181f3eb06
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:Estimate patient adherence to glaucoma medications and identify potential determinants of nonadherence. DESIGN:Descriptive study. METHODS:Two hundred patients with open angle glaucoma, ocular hypertension, or glaucoma suspects were interviewed regarding their glaucoma and its treatment and their charts were r...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e3181815421
更新日期:2009-03-01 00:00:00
abstract:PURPOSE:To examine clinical outcomes following an initial trabeculectomy with mitomycin-C for secondary glaucoma associated with uveitis in Behçet disease (BD) patients. DESIGN:Retrospective interventional case series. PATIENTS AND METHODS:Twenty-two eyes in 18 patients with uveitic glaucoma (UG) associated with Behç...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000665
更新日期:2017-07-01 00:00:00
abstract:OBJECTIVES:To evaluate the outcomes of trabeculectomy with mitomycin-C (MMC) in uveitis associated with Vogt-Koyanagi-Harada disease (VKH). METHODS:Retrospective cohort study included 27 eyes of 15 patients with uveitic glaucoma associated with VKH disease who underwent trabeculectomy with MMC as a first glaucoma proc...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0000000000000384
更新日期:2016-06-01 00:00:00
abstract:PURPOSE:To determine whether a structure-function model developed for normal age-related losses of retinal ganglion cells also models the retinal ganglion cell losses in glaucomatous optic neuropathy. METHODS:The model to relate age-related loss of retinal nerve fiber layer thickness and reduced sensitivity for standa...
journal_title:Journal of glaucoma
pub_type: 杂志文章
doi:10.1097/IJG.0b013e31820bcfbe
更新日期:2012-02-01 00:00:00