Abstract:
:The various antihypertensive regimens have varying effects on glucose metabolism and the development of diabetes mellitus. Recent large hypertension trials have shown great differences in the development of new-onset diabetes among antihypertensive drug therapies. The incidence of diabetes is unchanged or increased by thiazide diuretics and b-adrenergic blockers, and unchanged or decreased by angiotensin-converting enzyme inhibitors, calcium channel blockers, and angiotensin-receptor blockers. The differences in new-onset diabetes mellitus have not influenced the outcome of cardiovascular mortality and morbidity in all of the large clinical trials, but drug-induced diabetes among hypertensive patients is known to carry the same cardiovascular risk as that seen in patients with previously known diabetes; however, it might take years for the increased risk to become apparent.
journal_name
Curr Hypertens Repjournal_title
Current hypertension reportsauthors
Aksnes TA,Reims HM,Kjeldsen SE,Mancia Gdoi
10.1007/s11906-005-0029-9keywords:
subject
Has Abstractpub_date
2005-08-01 00:00:00pages
298-303issue
4eissn
1522-6417issn
1534-3111journal_volume
7pub_type
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