Abstract：
:The objective of the present study was to relate changes in certain muscle characteristics and indicators of metabolism in response to endurance training to the concomitant changes in time to exhaustion (T(lim)) at a work rate corresponding to maximal oxygen uptake VO(2speak). Eight healthy sedentary subjects pedalled on a cycle ergometer 2 h a day, 6 days a week, for 4 weeks. Training caused increases in VO(2peak) (by 8%), T(lim) (from 299 +/- 23 s before to 486 +/- 63 s after training), citrate synthase and 3-hydroxyl-acyl-CoA dehydrogenase (HAD) activities (by 54% and 16%, respectively) and capillary density (by 31%). Decreases in activity of lactate dehydrogenase (LDH) and muscle type of LDH (by 24% and 28%, respectively) and the phosphofructokinase/citrate synthase ratio (by 37%) were also observed. Respiratory exchange ratio (RER) tended to be lower (P < 0.1) at all relative work rates after training while the corresponding ventilation rates (VE) were unchanged. At the same absolute work rate, RER and (VE) were lower after training (P < 0.05). The improvement of T(lim) with training was related to the increases in HAD activity (r = 0.91, P = 0.0043), and to the decreases in RER calculated for Pa(peak) (r = 0.71, P = 0.0496). The present results suggest that the training-induced adaptations in fat metabolism might influence T(lim) at a work rate corresponding to VO(2peak) and stimulate the still debated and incompletely understood role of fat metabolism during short high-intensity exercise.
journal_name
Eur J Appl Physioljournal_title
European journal of applied physiologyauthors
Messonnier L,Denis C,Prieur F,Lacour JRdoi
10.1007/s00421-005-1325-4keywords:
subject
Has Abstractpub_date
2005-07-01 00:00:00pages
434-41issue
4eissn
1439-6319issn
1439-6327journal_volume
94pub_type
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journal_title：European journal of applied physiology
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journal_title：European journal of applied physiology
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journal_title：European journal of applied physiology
pub_type： 杂志文章
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journal_title：European journal of applied physiology
pub_type： 杂志文章,随机对照试验
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