The role of vegetable and fruit consumption in the aetiology of squamous cell carcinoma of the oesophagus: a case-control study in Uruguay.

abstract：:Squamous cell carcinoma of the conjunctiva (SCCC) has been associated with HIV infection in equatorial Africa, but the evidence for association with HIV in developed countries, where SCCC is rarer, is controversial. We investigated the risk for SCCC and other eye cancers in the updated U.S. HIV/AIDS Cancer Match Regis...

journal_title：International journal of cancer

authors： Guech-Ongey M,Engels EA,Goedert JJ,Biggar RJ,Mbulaiteye SM

更新日期：2008-06-01 00:00:00

abstract：:Six oncogenic cell lines were established from primary sarcomas that had been induced in thymectomized, aged, BALB/cSt mice by the injection of 3-methylcholanthrene. Of these lines, three produced B-tropic murine leukemia virus (MuLV), i.e. MuLV that would patently infect fibroblasts of BALB/c origin but not those fro...

journal_title：International journal of cancer

authors： Gillespie GY,Jensen FC,Russell SW

更新日期：1978-02-15 00:00:00

abstract：:Representational difference analysis was used to identify genes that are expressed in a human melanoma cell line and not in normal skin. A cDNA clone that appeared to be specific for tumors was obtained and the corresponding gene was sequenced. This new gene was named LAGE-I. Using a LAGE-I probe to screen a cDNA libr...

journal_title：International journal of cancer

authors： Lethé B,Lucas S,Michaux L,De Smet C,Godelaine D,Serrano A,De Plaen E,Boon T

更新日期：1998-06-10 00:00:00

abstract：:Little is known about age-dependent variation in outcomes of cervical cytology with modern technologies. This population-based study evaluated age-dependent changes after routine implementation of ThinPrep and SurePath technology in two independent laboratories, and controlled for time trends in a third laboratory usi...

journal_title：International journal of cancer

authors： Rask J,Lynge E,Franzmann M,Hansen B,Hjortebjerg A,Rygaard C,Schledermann D,Wåhlin A,Rebolj M

更新日期：2014-05-01 00:00:00

abstract：:We examined the biologic properties of a small-cell-lung-carcinoma (SCLC) cell line (designated MN-1112) established from a patient with SCLC who showed paraneoplastic retinopathy syndrome. Morphologic and immunocytochemical analyses showed that MN-1112 cells possess features of the classic type of SCLC. MN-1112 cells...

journal_title：International journal of cancer

authors： Yamaji Y,Matsubara S,Yamadori I,Sato M,Fujita T,Fujita J,Takahara J

更新日期：1996-03-01 00:00:00

abstract：:A panel of monoclonal antibodies and other markers (e.g., terminal deoxynucleotidyl transferase, sheep erythrocyte rosettes, peanut agglutinin) have been used in conjunction with flow cytometry and biochemical analysis to monitor the induction of maturation in human thymic (T) leukaemic cell lines by phorbol ester (TP...

journal_title：International journal of cancer

authors： Delia D,Greaves MF,Newman RA,Sutherland DR,Minowada J,Kung P,Goldstein G

更新日期：1982-01-15 00:00:00

abstract：:Antibodies to the 27 kDa heat shock protein (hsp27) are present in some women with ovarian and endometrial cancers but not in women with nonmalignant conditions or healthy women. The appearance of these antibodies suggests that the corresponding protein (hsp27) may be present in an extracellular form in gynecologic ca...

journal_title：International journal of cancer

authors： Korneeva I,Caputo TA,Witkin SS

更新日期：2002-12-10 00:00:00

abstract：:The Epstein-Barr virus nuclear antigen I (EBNA I) is the only latent EBV antigen consistently expressed in malignant tissues of the nasopharynx. A 20-amino-acid synthetic peptide, p107 contains a major epitope of EBNA I. We tested sera from 210 patients with nasopharyngeal carcinoma (NPC) and from 128 normal individua...

journal_title：International journal of cancer

authors： Foong YT,Cheng HM,Sam CK,Dillner J,Hinderer W,Prasad U

更新日期：1990-06-15 00:00:00

abstract：:Inbred rats were treated with extranuclear tumour membrane fractions or 3 M KCl-solubilized extracts of two antigenically distinct 3-methylcholanthrene-induced sarcomas, Mc7 and Mc57. The rats developed tumour-specific humoral antibody responses, but were not immune to tumour challenge. Moreover, they were unresponsiv...

journal_title：International journal of cancer

authors： Embleton MJ

更新日期：1976-11-15 00:00:00

abstract：:Daphnane-type diterpene gnidimacrin isolated from the Chinese plant Stellera chamaejasme L. is an antitumor agent that activates protein kinase C (PKC). The mechanism of antitumor action of gnidimacrin and the possible involvement of PKC were examined using sensitive K562 and refractory HLE cells. Gnidimacrin did bind...

journal_title：International journal of cancer

authors： Yoshida M,Yokokura H,Hidaka H,Ikekawa T,Saijo N

更新日期：1998-07-17 00:00:00

abstract：:We investigated the expression pattern of the breast cancer associated gene LIV-1 on mRNA and protein level in 111 human breast cancer patients by in situ hybridization as well as immunohistochemistry and focused on the unknown potential of LIV-1 expression levels as a prognostic marker. To our knowledge, this is the ...

journal_title：International journal of cancer

authors： Kasper G,Weiser AA,Rump A,Sparbier K,Dahl E,Hartmann A,Wild P,Schwidetzky U,Castaños-Vélez E,Lehmann K

更新日期：2005-12-20 00:00:00

abstract：:Resistance to cisplatin-based chemotherapy is a major cause of treatment failure in human ovarian cancer. Wild-type TP53 status is often, but not always, associated with cisplatin sensitivity, suggesting that additional factors may be involved. Overexpression/activation of the phosphatidylinositol-3-kinase/Akt pathway...

journal_title：International journal of cancer

authors： Fraser M,Bai T,Tsang BK

更新日期：2008-02-01 00:00:00

abstract：:The partition-defective 3 (PAR-3) protein is implicated in the development and maintenance of cell polarity and is associated with proteins that mediate the changes in cytoskeleton organization required for cell polarity establishment. In this work, we used two original primary cell lines (R-180 and R-305) derived fro...

journal_title：International journal of cancer

authors： Dugay F,Le Goff X,Rioux-Leclerq N,Chesnel F,Jouan F,Henry C,Cabillic F,Verhoest G,Vigneau C,Arlot-Bonnemains Y,Belaud-Rotureau MA

更新日期：2014-05-01 00:00:00

abstract：:Fatty acid ester surfactants, e.g., Cremophor EL and Solutol HS 15, that modulate multi-drug resistance (MDR) have been described; however, the drug potential of these preparations is unclear because of the molecular heterogeneity of these and other commercial surfactants. In previous experiments, an active but still ...

journal_title：International journal of cancer

authors： Buckingham LE,Balasubramanian M,Safa AR,Shah H,Komarov P,Emanuele RM,Coon JS

更新日期：1996-01-03 00:00:00

abstract：:We investigated whether the concentration of fibronectin (FN) in the cerebrospinal fluid (CSF) could be used for identifying patients with subclinical blast-cell infiltration in the central nervous system (CNS) and an increased risk of CNS relapse later in the course of their leukemia. Our series comprised 36 children...

journal_title：International journal of cancer

authors： Rautonen J,Koskiniemi M,Siimes MA,Salonen EM,Vaheri A

更新日期：1989-01-15 00:00:00

abstract：:B-cell chronic lymphocytic leukaemia (B-CLL) cells fail to undergo apoptosis. The mechanism underlying this resistance to cell death is still largely unknown. Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) effectively kills tumour cells but not normal cells, and thus represents an attractive tool for...

journal_title：International journal of cancer

authors： Garofalo M,Romano G,Quintavalle C,Romano MF,Chiurazzi F,Zanca C,Condorelli G

更新日期：2007-03-15 00:00:00

abstract：:The aim of this study was to construct bispecific F(ab')2 [anti-CD3 x anti-BCL1 idiotype (Id)] Abs (BsAbs) which would enable lymphokine-activated killer (LAK) T cells to kill Id+ mouse BCL1 lymphoma cells, and to determine the mechanism(s) underlying cell death. Using 4-day activated LAK T cells from either perforin-...

journal_title：International journal of cancer

authors： Armstrong JM,Vitetta ES

更新日期：1996-12-11 00:00:00

abstract：:The factors associated with risk of lung cancer among nonsmokers have not been fully elucidated, but dietary factors have consistently been shown to play a role. Chinese women are unique in having a high incidence of lung cancer despite a low smoking prevalence. This population is also known to have a high intake of s...

journal_title：International journal of cancer

authors： Seow A,Poh WT,Teh M,Eng P,Wang YT,Tan WC,Chia KS,Yu MC,Lee HP

更新日期：2002-01-20 00:00:00

abstract：:Epstein-Barr virus genome-positive Burkitt's lymphoma is endemic in Africa and Papua New Guinea and in both countries the tumour is restricted to regions with holoendemic malaria. The present work has compared groups of healthy indigenous individuals living in malarious and non-malarious regions of Papua New Guinea fo...

journal_title：International journal of cancer

authors： Moss DJ,Burrows SR,Castelino DJ,Kane RG,Pope JH,Rickinson AB,Alpers MP,Heywood PF

更新日期：1983-06-15 00:00:00

abstract：:Regulatory T cells (Treg) mediate amelioration of disease and immune homeostasis by inhibiting immune activation and maintaining peripheral immune tolerance. The suppressive mechanisms and clinical significance of Treg have not been completely elucidated in patients with acute myeloid leukemia (AML). Here, we demonstr...

journal_title：International journal of cancer

authors： Shenghui Z,Yixiang H,Jianbo W,Kang Y,Laixi B,Yan Z,Xi X

更新日期：2011-09-15 00:00:00

abstract：:Pancreatic adenocarcinoma (PDAC) is known to have a poor prognosis partly because of lack of effective biomarkers. In the test set, we investigated dysbindin (DTNBP1) as a potential biomarker for PDAC by comparing preoperative and postoperative serum mass spectrometry (MS) proteomic profilings. Of the included 50 PDAC...

journal_title：International journal of cancer

authors： Guo X,Lv X,Fang C,Lv X,Wang F,Wang D,Zhao J,Ma Y,Xue Y,Bai Q,Yao X,Chen Y

更新日期：2016-10-15 00:00:00

abstract：:The tumor site is a strong clinical factor in head and neck squamous cell carcinoma (HNSCC). To clarify the biologic and clinical role of p53 alterations in HNSCC, we have examined the prevalence and the nature of p53 alterations in a large cohort of tumors from the different sites. For immunohistochemical analysis of...

journal_title：International journal of cancer

authors： Bosch FX,Ritter D,Enders C,Flechtenmacher C,Abel U,Dietz A,Hergenhahn M,Weidauer H

更新日期：2004-09-10 00:00:00

abstract：:The purpose of this study was to assess the relationship between progression-free survival (PFS) in patients treated with DFMO + PCV (procarbazine, CCNU, vincristine) chemotherapy for malignant gliomas with tumor cell ornithine decarboxylase (ODC) activity. Formalin-fixed slides were obtained for study patients with a...

journal_title：International journal of cancer

authors： Levin VA,Jochec JL,Shantz LM,Aldape KD

更新日期：2007-11-15 00:00:00

abstract：:We previously found that the gene encoding the Myelin and Lymphocyte protein, MAL, was among the most highly expressed genes in serous ovarian cancers from short-term survivors (<3 years) relative to those of long-term survivors (>7 years). In the present study, we have found that this difference in expression is part...

journal_title：International journal of cancer

authors： Lee PS,Teaberry VS,Bland AE,Huang Z,Whitaker RS,Baba T,Fujii S,Secord AA,Berchuck A,Murphy SK

更新日期：2010-03-15 00:00:00

abstract：:Akt is a promising therapeutic target for cancer treatment. In our study, we have identified that 7-deoxynarciclasine (7-DONCS) is a potential inhibitor of Akt, which results in the repression of multiple oncogenic processes in hepatocellular carcinoma (HCC). We have found that 7-DONCS suppresses the growth of HCC by ...

journal_title：International journal of cancer

authors： Yin S,Qiu Y,Jin C,Wang R,Wu S,Liu H,Koo S,Han L,Zhang Y,Gao X,Pang X,Wang T,Yu H

更新日期：2019-12-15 00:00:00

abstract：:With the improvement of treatments, a growing number of survivors with childhood or adolescent central nervous system (CNS) tumor are parenting their own children. We aimed to explore the risk of somatic diseases among children of these survivors compared to population controls. Children of survivors with CNS tumor be...

journal_title：International journal of cancer

authors： Huang W,Sundquist K,Sundquist J,Ji J

更新日期：2020-11-13 00:00:00

abstract：:Immunization of mice with 10(6) irradiated LSTRA murine leukemia cells (LX) induced weak immunity to subsequent tumor-cell challenge. Admixture of low doses (1.4-14 micrograms of C. parvum with the LX usually augmented the immunity. Higher doses (1,400-7,000 micrograms) of admixed C. parvum not only failed to augment ...

journal_title：International journal of cancer

authors： Titus MJ,Bartlett GL,Kreider JW

更新日期：1982-06-15 00:00:00

abstract：:IL-2 gene was introduced through retroviral vectors into the highly malignant and poorly immunogenic 3LL-D122 clone. Both high and low D122-IL-2 secretors showed elimination of tumorigenicity in syngeneic immune-competent mice; however, in nude mice only the high IL-2 secretor showed reduced tumorigenicity as compared...

journal_title：International journal of cancer

authors： Porgador A,Gansbacher B,Bannerji R,Tzehoval E,Gilboa E,Feldman M,Eisenbach L

更新日期：1993-02-01 00:00:00

abstract：:Telomerase appears to be an important factor for the control of cellular proliferation capacity and for tumorigenesis. Enzyme activity is highly increased in almost all human tumors and distinguishes them from benign lesions. Besides its diagnostic value, telomerase activity appears to be associated with tumor progres...

journal_title：International journal of cancer

authors： Hoos A,Hepp HH,Kaul S,Ahlert T,Bastert G,Wallwiener D

更新日期：1998-02-20 00:00:00

abstract：:Non-steroidal anti-inflammatory drugs (NSAIDs), including aspirin, seem to have chemopreventive properties against several types of cancer, particularly colon cancer. Persons with rheumatoid arthritis, an autoimmune disease for which NSAIDs are used commonly, have been reported to be at lower risk of colon cancer but ...

journal_title：International journal of cancer

authors： Cerhan JR,Anderson KE,Janney CA,Vachon CM,Witzig TE,Habermann TM

更新日期：2003-09-20 00:00:00