Changes of 5-HT receptor subtype mRNAs in rat dorsal root ganglion by bee venom-induced inflammatory pain.

abstract：:AMPA receptor (AMPAR) trafficking has emerged as a fundamental concept for understanding mechanisms of learning and memory as well as many neurological disorders. Classical conditioning is a simple and highly conserved form of associative learning. Our studies use an ex vivo brainstem preparation in which to study cel...

journal_title：Neuroscience letters

authors： Keifer J,Tiwari NK,Buse L,Zheng Z

更新日期：2017-04-03 00:00:00

abstract：:Human sweat and sebaceous glands were studied immunohistochemically with a monoclonal antibody recognizing a vasoactive intestinal polypeptide (VIP) receptor. The staining pattern correlated well with the known distribution of sympathetic VIP-containing nerves in the human skin. The luminal cell layer of the sweat gla...

journal_title：Neuroscience letters

authors： Kummer W,Herbst WM,Heym C

更新日期：1990-03-14 00:00:00

abstract：:Several studies have demonstrated that the human motor cortex is activated by the mere observation of actions performed by others. In the present study, we explored whether the perception of 'impoverished motion stimuli', such as shadow animations, is sufficient to activate motor areas. To do so, transcranial magnetic...

journal_title：Neuroscience letters

authors： Alaerts K,Van Aggelpoel T,Swinnen SP,Wenderoth N

更新日期：2009-09-25 00:00:00

abstract：:The present investigation assessed the effect of chronic blockade of kainate/quisqualate binding sites with 6-cyano-7-nitroquinoxaline-2,3-dione (CNQX) on preproenkephalin (PPE) and preprotachykinin (PPT) mRNA abundance in the neostriatum of the rat brain. Daily injection of CNQX for seven consecutive days decreased P...

journal_title：Neuroscience letters

authors： Villegas M,Angulo JA

更新日期：1995-05-19 00:00:00

abstract：:Dopamine receptor D4 (DRD4) is activated by the neurotransmitter dopamine and links to many neurological and psychiatric conditions because of its close relationship with prefrontal cortex and other important brain regions. To explore the possibility that genetic variants of DRD4 gene predispose to children with menta...

journal_title：Neuroscience letters

authors： Zhang K,Zhang M,He H,Zhang J,Chi W,Guo Y,Huang S,Zheng Z,Zhang F,Gao X

更新日期：2012-05-10 00:00:00

abstract：:The objective of this study was to investigate whether berberine in Coptidis Rhizoma extract could be transported in primary cultured cerebral neurons and to study the uptake and transport behavior of berberine through the neurons. The present results showed that the uptake of berberine by the neurons increased linear...

journal_title：Neuroscience letters

authors： Wang X,Xing D,Wang W,Lei F,Su H,Du L

更新日期：2005-05-06 00:00:00

abstract：:The possibility that single electrical shock stimulation of somatic afferent nerves could evoke a reflex response in vagal efferent nerves innervating the stomach was examined using anesthetized, artificially-ventilated rats. A single shock to a hindlimb afferent nerve (tibial nerve) produced two distinct reflex compo...

journal_title：Neuroscience letters

authors： Kimura A,Sato A,Sato Y,Suzuki A

更新日期：1996-05-24 00:00:00

abstract：:To elucidate the early histopathological changes after transient focal cerebral ischemia, we made 1 h intraluminal occlusion of the middle cerebral artery on rats. After different reperfusion time, from minutes to 3 days, argyrophil III method was used for the demonstration of 'collapsed' (argyrophilic, dark) neurons....

journal_title：Neuroscience letters

authors： Czurkó A,Nishino H

更新日期：1993-11-12 00:00:00

abstract：:Previous studies showed egocentric but not allocentric mental rotation tasks to be impaired in microgravity when feedback cues about vertical surroundings were restricted. Those studies are difficult to reconcile, however, since they were limited not only to small subject groups, but also differed dramatically in desi...

journal_title：Neuroscience letters

authors： Dalecki M,Dern S,Steinberg F

更新日期：2013-01-15 00:00:00

abstract：:Dependency of taste buds and taste papillae on innervation has been debated for a long time. Previous research showed neurotrophins, brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3), play an important role for the establishment of the lingual gustatory and somatosensory innervation. BDNF null mutant ...

journal_title：Neuroscience letters

authors： Ito A,Nosrat IV,Nosrat CA

更新日期：2010-03-08 00:00:00

abstract：:The distribution and cellular localisation of somatostatin receptor subtype 4 (SSTR4) was investigated in the adult rat brain using the technique of in situ hybridisation with subtype specific oligonucleotide probes. Somatostatin receptor subtype 4 was found mainly in the hippocampus CA1 > CA2 > CA3 pyramidal cells an...

journal_title：Neuroscience letters

authors： Harrington KA,Schindler M,Humphrey PP,Emson PC

更新日期：1995-03-16 00:00:00

abstract：:The level of endogenous nerve growth factor (NGF) in rat sciatic nerve was determined using a highly sensitive two-site enzyme immunoassay. After crushing this nerve NGF accumulated linearly distal to the crush during the first 12 h to reach levels 13-fold higher than in the uncrushed contralateral side. In contrast, ...

journal_title：Neuroscience letters

authors： Korsching S,Thoenen H

更新日期：1983-08-19 00:00:00

abstract：:CART peptides are important neurotransmitters, but little is known about their receptors or signaling pathways in cells. In this study we describe the effects of CART 55-102 on the stimulation of extracellular signal-related kinase (ERK) in a pituitary-derived cell line. CART 55-102 treatment resulted in markedly enha...

journal_title：Neuroscience letters

authors： Lakatos A,Prinster S,Vicentic A,Hall RA,Kuhar MJ

更新日期：2005-08-12 00:00:00

abstract：:A peptide consisting of residues 25-35 of the amyloid beta protein was applied to single neurons while monitoring membrane current by whole cell voltage clamp recording. Within minutes of direct exposure of a neuron to the amyloid beta peptide, a paroxysmal increase in neuronal membrane conductance was observed. This ...

journal_title：Neuroscience letters

authors： Simmons MA,Schneider CR

更新日期：1993-02-19 00:00:00

abstract：:Samples of human cerebral cortex were stained immunocytochemically for tyrosine hydroxylase (TH) and gamma-aminobutyric acid (GABA). TH-positive neurons were in small number and predominated in the deep infragranular layers V-VI contrasting with numerous GABA-positive neurons scattered in all layers. Co-localization o...

journal_title：Neuroscience letters

authors： Trottier S,Geffard M,Evrard B

更新日期：1989-11-20 00:00:00

abstract：:To determine whether diabetes mellitus alters the lipid order and composition of cerebral microvessels, streptozotocin-induced diabetic rats were studied after 5 weeks of chronic hyperglycemia. Diabetes did not affect membrane order or the thermotropic transition temperature of cerebral microvessels as determined from...

journal_title：Neuroscience letters

authors： Mooradian AD,Smith TL

更新日期：1992-10-12 00:00:00

abstract：:The regional cerebral blood flow (rCBF) was measured with positron emission tomography in eight normal volunteers with the purpose of measuring rCBF changes related to the comprehension of an unfamiliar spoken languages. When attempting to comprehend the meaning of words, the left hemisphere showed dominant increases ...

journal_title：Neuroscience letters

authors： Kawashima R,Itoh M,Hatazawa J,Miyazawa H,Yamada K,Matsuzawa T,Fukuda H

更新日期：1993-10-14 00:00:00

abstract：:An abnormal distribution of phosphorylated neurofilaments is present in some human neurodegenerative disorders including Parkinson's disease, Alzheimer's disease, and amyotrophic lateral sclerosis. This study reports the changes of phosphorylated neurofilaments observed in rat spinal cord after intrathecal injection o...

journal_title：Neuroscience letters

authors： Hugon J,Vallat JM

更新日期：1990-10-30 00:00:00

abstract：:Conduction velocities of antidromically evoked impulses along the goldfish Mauthner axon were found to be inversely correlated with body length. To test the hypothesis that such a relation is accompanied by a reduction in axonal diameter with increasing fish size, Mauthner axon diameters were measured. A parabolic rel...

journal_title：Neuroscience letters

authors： Funch PG,Kinsman SL,Faber DS,Koenig E,Zottoli SJ

更新日期：1981-12-11 00:00:00

abstract：:The nucleus raphe magnus belongs to the thermoafferent system. Following iontophoretic choleratoxin b injections in its rostral part, a substantial to large number of anterogradely labeled varicose fibres were observed in the medial and lateral preoptic areas, the bed nucleus, the substantia innominata, the ventral pa...

journal_title：Neuroscience letters

authors： Hermann DM,Luppi PH,Peyron C,Hinckel P,Jouvet M

更新日期：1996-10-04 00:00:00

abstract：:The epsilon4 allele of the apolipoprotein E gene (APOE) has repeatedly been associated with increased risk for Alzheimer's disease (AD). Bullido and colleagues recently identified a polymorphism in the promoter region of the APOE gene (-491A/T) and found that -491A homozygosity predicted AD independently of APOE epsil...

journal_title：Neuroscience letters

authors： Town T,Paris D,Fallin D,Duara R,Barker W,Gold M,Crawford F,Mullan M

更新日期：1998-08-14 00:00:00

abstract：:In this study, it was investigated whether context-dependent sensitization of catalepsy changes the firing pattern in striatum. Rats were treated with either haloperidol (0.5 mg/kg i.p.) or saline, and tested on catalepsy with a concomitant single-unit measurement of the spiny I activity. Administration of haloperidol...

journal_title：Neuroscience letters

authors： Frank ST,Schmidt WJ

更新日期：2004-01-02 00:00:00

abstract：:Experiments were done in conscious rats to investigate the effect of intravenous infusion of hypertonic saline on the induction of the protein Fos, in brainstem neurons. Neurons containing Fos-like immunoreactivity were observed in the caudal nucleus of the solitary tract (NTS), the caudal and rostral ventrolateral me...

journal_title：Neuroscience letters

authors： Hochstenbach SL,Solano-Flores LP,Ciriello J

更新日期：1993-08-20 00:00:00

abstract：:The present study shows that cultured fibroblasts from sporadic Alzheimer's disease patients are deficient in protein kinase C-regulated secretion of amyloid precursor protein. In particular, Alzheimer fibroblasts show a reduced basal secretion and a reduced response at low concentrations of phorbol-12,13-dibutyrate, ...

journal_title：Neuroscience letters

authors： Bergamaschi S,Binetti G,Govoni S,Wetsel WC,Battaini F,Trabucchi M,Bianchetti A,Racchi M

更新日期：1995-12-01 00:00:00

abstract：:The insular cortex (IC) processes multimodal sensory information including gustatory, visceral, nociceptive, and thermal sensation, and is considered to play a role in the regulation of homeostasis. The IC receives dense histaminergic projection from the tuberomamillary nucleus in the hypothalamus, and recent studies ...

journal_title：Neuroscience letters

authors： Takei H,Song L,Ebihara K,Shirakawa T,Koshikawa N,Kobayashi M

更新日期：2012-06-14 00:00:00

abstract：:Occurrence of neurocalcin, a calcium-binding protein with three EF hand motifs, was examined immunohistochemically in the rat olfactory epithelium and vomeronasal organ epithelium. Immunoreactivity was detected in receptor cells in these epithelia. Immunoreactions were distributed in cytoplasm associated with outer mi...

journal_title：Neuroscience letters

authors： Iino S,Kobayashi S,Okazaki K,Hidaka H

更新日期：1995-05-19 00:00:00

abstract：:The effects of the serotonin agonist MK-212, on rat plasma ACTH were examined. MK-212 significantly increased plasma ACTH levels, and this effect was blocked by the 5-HT1C antagonists mesulergine and metergoline but not by spiperone, ketanserin, or (-)-pindolol. The results suggest that MK-212 activates the 5-HT1C rec...

journal_title：Neuroscience letters

authors： King BH,Brazell C,Dourish CT,Middlemiss DN

更新日期：1989-10-23 00:00:00

abstract：:The effect of dexmedetomidine, a selective alpha2-adrenoreceptor agonist and neuroprotective agent on the expression of immediate early genes and heat shock protein hsp70, was studied using quantitative in situ hybridization in a global ischemia model. At the dose previously shown to be neuroprotective dexmedetomidine...

journal_title：Neuroscience letters

authors： Wittner M,Sivenius J,Koistinaho J

更新日期：1997-08-29 00:00:00

abstract：:Brain-derived neurotrophic factor (BDNF) and insulin promote the survival of 6-7 day old post-natal rat cerebellar granule cells. Previous studies using the PI3 kinase inhibitor, wortmannin and the over-expression of protein kinase B (PKB) have indicated that both PI3 kinase and PKB activation are central for insulin-...

journal_title：Neuroscience letters

authors： Foulstone EJ,Tavaré JM,Gunn-Moore FJ

更新日期：1999-04-02 00:00:00

abstract：:Five monkeys vocalizing at self-pace (self-paced vocalization) were well trained to vocalize in response to a monkey call (audio-initiated vocalization). Field potentials associated with audio-initiated vocalizations were recorded by using electrodes which were implanted chronically on the surface and at a 2.0-3.0 mm ...

journal_title：Neuroscience letters

authors： Gemba H,Kyuhou S,Matsuzaki R,Amino Y

更新日期：1999-09-03 00:00:00