Laparoscopic radical prostatectomy: prospective evaluation of the learning curve.

Abstract:

OBJECTIVE:We prospectively evaluated the learning curve (LC) of laparoscopic radical prostatectomy (L-RPE) regarding the improvements in operative times (OT) and technical difficulty in one-operator-practice as it compares with open RPE. METHODS:Over 18 months, 50 L-RPE were performed by an inexperienced surgeon in laparoscopy but skilled in open surgery. Difficulty scores were obtained at the completion of each L-RPE comparing L-RPE to open RPE. OT, estimated blood loss (EBL), length of stay, and catheterization time were also obtained. RESULTS:In the ablative part of L-RPE the median difficulty score was significantly higher (p<0.001) for the first 10 cases, decreased dramatically by case 11 becoming equivalent (p=0.3) to open RPE and by case 31 the L-RPE becomes significantly easier than open RPE (p=0.002). The difficulty scores for the urethrovesical anastomosis performance is always uniformly higher for the whole patient series (p<0.001). Median OT decreased significantly from 293 minutes in the first 10 cases to 114 minutes in the last 10 cases (p<0.001). Catheterization time and length of hospitalization, decreased significantly with the progression of the LC. EBL remained stable throughout the patient cases. Obesity, prior surgery, and extension of the procedure (lymphadenectomy, nerve-sparing) significantly increased the OT. CONCLUSION:Although the ablative part of L-RPE has a relatively short LC for a skilled open surgeon reflected by the rapid decrease in difficulty scores and OT by case 21, the performance of anastomosis shows a longer LC. Intensive training on anastomosis may be necessary to master this skill.

journal_name

Eur Urol

journal_title

European urology

authors

Poulakis V,Dillenburg W,Moeckel M,de Vries R,Witzsch U,Zumbé J,Rassweiler J,Becht E

doi

10.1016/j.eururo.2004.09.006

keywords:

subject

Has Abstract

pub_date

2005-02-01 00:00:00

pages

167-75

issue

2

eissn

0302-2838

issn

1873-7560

pii

S0302-2838(04)00465-8

journal_volume

47

pub_type

杂志文章
  • Combination of diffusion-weighted magnetic resonance imaging and extended prostate biopsy predicts lobes without significant cancer: application in patient selection for hemiablative focal therapy.

    abstract:BACKGROUND:Significant cancer in contralateral sides of the prostate that was missed on prostate biopsy (PBx) is a concern in hemiablative focal therapy (FT) of prostate cancer (PCa). However, extended PBx, a common diagnostic procedure, has a limited predictive ability for lobes without significant cancer. OBJECTIVE:...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2012.10.010

    authors: Matsuoka Y,Numao N,Saito K,Tanaka H,Kumagai J,Yoshida S,Koga F,Masuda H,Kawakami S,Fujii Y,Kihara K

    更新日期:2014-01-01 00:00:00

  • Is the diet of patients with interstitial cystitis related to their disease?

    abstract:OBJECTIVE:The dietary habits of interstitial cystitis (IC) patients compared to the average food and fluid consumption of the general population were evaluated and any spontaneous preference or avoidance of specific foodstuffs and fluids of IC patients was investigated. METHODS:A verbal interview with 16 IC patients p...

    journal_title:European urology

    pub_type: 杂志文章

    doi:

    authors: Bade JJ,Peeters JM,Mensink HJ

    更新日期:1997-01-01 00:00:00

  • Retroperitoneal laparoscopic radical nephrectomy for renal cell carcinoma with infrahepatic vena caval thrombus.

    abstract:PURPOSE:The retroperitoneal laparoscopic approach is utilized to treat a right renal tumor with vena caval thrombus reaching infrahepatic veins. MATERIALS AND METHODS:The patient is an 87-year-old woman with a tumor measuring 8 x 9 cm and a vena caval thrombus (7 cm), stretching as far as the subhepatic vein. The retr...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2004.11.010

    authors: Disanto V,Pansadoro V,Portoghese F,Scalese GA,Romano M

    更新日期:2005-03-01 00:00:00

  • Casodex 10-200 mg daily, used as monotherapy for the treatment of patients with advanced prostate cancer. An overview of the efficacy, tolerability and pharmacokinetics from three phase II dose-ranging studies. Casodex Study Group.

    abstract:OBJECTIVES:To evaluate the efficacy, tolerability, endocrinological effects and the pharmacokinetics of Casodex, when given as monotherapy during daily dosing of 10-200 mg to patients with advanced prostate cancer. METHODS:A total of 390 patients with advanced prostate cancer were treated for a minimum of 12 weeks wit...

    journal_title:European urology

    pub_type: 临床试验,杂志文章

    doi:10.1159/000019526

    authors: Tyrrell CJ,Denis L,Newling D,Soloway M,Channer K,Cockshott ID

    更新日期:1998-01-01 00:00:00

  • Cost-effectiveness Analysis of Active Surveillance Strategies for Men with Low-risk Prostate Cancer.

    abstract:BACKGROUND:Active surveillance (AS) has become the recommended management strategy for men with low-risk prostate cancer. However, there is considerable uncertainty about the optimal follow-up schedule in terms of the tests to perform and their frequency. OBJECTIVE:To assess the costs and benefits of different AS foll...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2018.10.055

    authors: Sathianathen NJ,Konety BR,Alarid-Escudero F,Lawrentschuk N,Bolton DM,Kuntz KM

    更新日期:2019-06-01 00:00:00

  • Nocturnal enuresis: basic facts and new horizons.

    abstract::Nocturnal enuresis in children is quite seldom due to psychological factors. Instead, it is caused by a hereditary delay in maturation of the somatic mechanisms (reduction of nocturnal urine production, relaxation of the bladder during sleeping hours, and a normal arousal to a full bladder) which prevent the child fro...

    journal_title:European urology

    pub_type: 杂志文章,评审

    doi:

    authors: Hjälmås K

    更新日期:1998-01-01 00:00:00

  • Localization and function of cannabinoid receptors in the corpus cavernosum: basis for modulation of nitric oxide synthase nerve activity.

    abstract:BACKGROUND:Anandamide, a proposed endogenous cannabinoid (CB) agonist, has been shown to enhance neurogenic responses in vitro of the rat corpus cavernosal tissue (CC). However, no information is available on the distribution of CB-receptors or effects by anandamide in CC from primates or humans. OBJECTIVE:To characte...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2008.12.024

    authors: Gratzke C,Christ GJ,Stief CG,Andersson KE,Hedlund P

    更新日期:2010-02-01 00:00:00

  • When should quality of life be measured after radical cystectomy?

    abstract:AIM:In this prospective study our aim was to establish the time it takes cystectomized patients' to adapt to their new health status. MATERIALS AND METHOD:A total of 68 patients, having radical cystectomy for bladder cancer (64 males and 4 females) were enrolled in the study. The mean age of the group was 55.4 +/- 8.0...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/s0302-2838(02)00351-2

    authors: Kulaksizoglu H,Toktas G,Kulaksizoglu IB,Aglamis E,Unlüer E

    更新日期:2002-10-01 00:00:00

  • Neuroendocrine differentiation in hormone refractory prostate cancer following androgen deprivation therapy.

    abstract:OBJECTIVE:To evaluate the relationship between neuroendocrine differentiation (NED) status and hormone refractory prostate cancer (HRPC) following hormone therapy based on immunohistochemical study. METHODS:Seventy-two prostate cancer specimens obtained at radical prostatectomy and 21 prostate cancer autopsy specimens...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2003.11.032

    authors: Hirano D,Okada Y,Minei S,Takimoto Y,Nemoto N

    更新日期:2004-05-01 00:00:00

  • Experimental model for ureteral autotransplantation in the rat.

    abstract::The development of an experimental model for ureteral autotransplantation without kidney transplantation, in an attempt to confirm viability of the ureter after denervation and total ischemia, is reported. Stages of the study and the experimental microsurgical technique used are discussed. Experiments were carried out...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000474727

    authors: Saladié JM,Blasco FJ

    更新日期:1992-01-01 00:00:00

  • Thick loop transurethral resection of the prostate.

    abstract:OBJECTIVES:To evaluate the safety and efficacy of the new resection loops for transurethral resection of the prostate (TURP). These loops, which are both thicker and have a modified shape, allow simultaneous resection, increased tissue vaporization, and improved hemostasis. METHODS:Two open studies have been performed...

    journal_title:European urology

    pub_type: 杂志文章,评审

    doi:10.1159/000019837

    authors: Perlmutter AP,Vallancien G

    更新日期:1999-02-01 00:00:00

  • Mechanisms of prostate atrophy after glandular botulinum neurotoxin type a injection: an experimental study in the rat.

    abstract:BACKGROUND:Previous studies in humans, dogs, and rats have shown that intraprostatic injection of botulinum neurotoxin type A (BoNTA) reduces gland size. OBJECTIVE:To investigate the role of eventual impairment of sympathetic, parasympathetic, and sensory nerves to gland atrophy after intraprostatic BoNTA administrati...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2008.07.003

    authors: Silva J,Pinto R,Carvallho T,Coelho A,Avelino A,Dinis P,Cruz F

    更新日期:2009-07-01 00:00:00

  • Surgical treatment of Peyronie's disease by the intracavernosal plaque excision method: a new surgical technique.

    abstract:OBJECTIVE:A new surgical method of treating Peyronie's disease consisting in intracavernosal excision of the plaque is presented. MATERIAL AND METHODS:The operation was performed on 16 men aged from 34 to 65 years (mean 50.2 years). The angle of penile curvature was 30 degrees to 60 degrees. Thirteen (81.25%) had impa...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2003.05.001

    authors: Darewicz JS,Darewicz BA,Galek LM,Kudelski J,Badri BM

    更新日期:2004-01-01 00:00:00

  • Tissue adhesives: their use in urology.

    abstract::Tissue adhesives have certain advantages and should be used only for nephropexy and urethropexy but not for orchiopexy. Because of possible incrustation it should be avoided in the urinary collecting system. ...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000471999

    authors: Kelâmi A

    更新日期:1976-01-01 00:00:00

  • Modified pubovaginal sling and Martius graft for repair of the recurrent vesicovaginal fistula involving the internal urinary sphincter.

    abstract::A modified Martius graft interposition flap was used in conjunction with the modified pubovaginal sling bladder suspension to treat a recurrent vesicovaginal fistula involving the proximal urethra and bladder neck. The patient recovered with no incontinence, voiding dysfunction or dyspareunia. Incontinence should be a...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000475169

    authors: Ghoniem GM,Monga M

    更新日期:1995-01-01 00:00:00

  • New method of postprostatectomy bladder irrigation.

    abstract::Bacterial filters have been used to sterilise the hospital water supply in order to provide irrigant for postprostatectomy irrigation. This method was compared retrospectively to bladder irrigation derived from a still on the ward. Postoperative bacteriuria was similar in both groups of 75 patients, occurring in 23.7%...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000471532

    authors: MacDermott JP,Ewing R,Gray BK

    更新日期:1989-01-01 00:00:00

  • The treatment satisfaction scale: a multidimensional instrument for the assessment of treatment satisfaction for erectile dysfunction patients and their partners.

    abstract:BACKGROUND:The development of the Treatment Satisfaction Scale (TSS) was previously reported (Kubin et al., 2004). OBJECTIVE:This article describes the psychometric validation process and psychometric properties (e.g., reliability, validity, and responsiveness) of TSS. METHODS:Initial patient and partner questionnair...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2005.05.008

    authors: DiBenedetti DB,Gondek K,Sagnier PP,Kubin M,Marquis P,Keininger D,Fugl-Meyer AR

    更新日期:2005-09-01 00:00:00

  • Treatment of anterior vaginal wall prolapse with porcine skin collagen implant by the transobturator route: preliminary results.

    abstract:OBJECTIVE:To assess the feasibility and efficacy of porcine skin collagen (Pelvicol) implant by the transobturator route for the treatment of anterior vaginal wall prolapse. PATIENTS AND METHODS:Twenty-seven women with stage III or IV prolapse underwent anterior vaginal wall repair with porcine skin collagen implantat...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2003.09.005

    authors: Salomon LJ,Detchev R,Barranger E,Cortez A,Callard P,Darai E

    更新日期:2004-02-01 00:00:00

  • Laparoscopic and robotic assisted radical prostatectomy--critical analysis of the results.

    abstract:OBJECTIVE:To evaluate the role of laparoscopic radical prostatectomy (LRP) and robotic assisted radical prostatectomy (RLRP) based on personal experience and a review of the literature. MATERIAL AND METHODS:Own experience at one European and one American LRP-center includes more than 2000 cases. We performed a MEDLINE...

    journal_title:European urology

    pub_type: 杂志文章,评审

    doi:10.1016/j.eururo.2005.12.054

    authors: Rassweiler J,Hruza M,Teber D,Su LM

    更新日期:2006-04-01 00:00:00

  • Reassessing the current UICC/AJCC TNM staging for renal cell carcinoma.

    abstract:CONTEXT:The outcome prediction for renal cell cancer (RCC) remains controversial, and although many parameters have been tested for prognostic significance, only a few have achieved widespread acceptance in clinical practice. The TNM staging system defines local extension of the primary tumour (T), involvement of regio...

    journal_title:European urology

    pub_type: 杂志文章,评审

    doi:10.1016/j.eururo.2009.06.036

    authors: Moch H,Artibani W,Delahunt B,Ficarra V,Knuechel R,Montorsi F,Patard JJ,Stief CG,Sulser T,Wild PJ

    更新日期:2009-10-01 00:00:00

  • Combined androgen blockade is the treatment of choice for patients with advanced prostate cancer: the argument for.

    abstract::Combined androgen blockade (CAB) is becoming standard treatment for patients with newly diagnosed advanced prostate cancer. This statement is based on the outcome and long-term evaluation of patients treated in prospective randomised trials. Particularly, patients with 'good' prognostic signs at the time of diagnosis ...

    journal_title:European urology

    pub_type: 杂志文章,评审

    doi:10.1159/000473836

    authors: Debruyne FM

    更新日期:1996-01-01 00:00:00

  • Sexual functioning of adult patients born with meningomyelocele. A pilot study.

    abstract:OBJECTIVES:This pilot study was started to get an impression of the sexual activity and sexual difficulties of adult patients born with meningomyelocele in control at Utrecht University Hospital, and to find out whether these problems deserve more attention from the Spina Bifida Team. METHODS:Seventeen patients (9 men...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000019673

    authors: Vroege JA,Zeijlemaker BY,Scheers MM

    更新日期:1998-01-01 00:00:00

  • Sigmoid kidney associated with renal adenocarcinoma.

    abstract::A rare case of adenocarcinoma in a sigmoid kidney is reported. The literature is reviewed and the operative technique described. Preoperative arteriogram and cavogram are an essential part of the evaluation and provide aid in the surgical approach. ...

    journal_title:European urology

    pub_type: 杂志文章

    doi:

    authors: Vandendris M,Schulman CC,Struyven J,Grégoir W

    更新日期:1975-01-01 00:00:00

  • Transitional cell carcinoma arising from bladder left behind.

    abstract::A case of transitional cell carcinoma arising from a bladder which was left behind for more than 24 years without pyocystis syndrome is described. A search in the literature revealed 10 cases of defunctionalized bladder that developed tumors over a rather short latent period ranging from 3 months to 7 years, and mostl...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000473114

    authors: Asano S,Matsuda M,Takemoto M,Osafune M,Sagawa S

    更新日期:1979-01-01 00:00:00

  • Screening for prostate cancer.

    abstract::Early-stage prostate cancer is usually asymptomatic and therefore, in the past, has often gone undetected, unless diagnosed by a digital rectal examination. More recently, new tests have been introduced, namely prostate-specific antigen and transrectal ultrasound, in order to improve the detection of early-stage disea...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000474379

    authors: Chodak GW

    更新日期:1993-01-01 00:00:00

  • Iglesias resectoscope with simultaneous irrigation, suction and low intravesical pressure.

    abstract::A resectoscope with continuous irrigation, suction and low intravesical pressure has been described. Advantages of this instrument include: no interruption, better endoscopic vision by a continuous clear inflow of more than 500 ml/min at 70 cm pressure, less bleeding, no air bubbles, constant intravesical pressure les...

    journal_title:European urology

    pub_type: 杂志文章

    doi:

    authors: Iglesias JJ,Fiore G

    更新日期:1975-01-01 00:00:00

  • Phosphodiesterase type 5 inhibitors: the day after.

    abstract:OBJECTIVE:Review the literature on phosphodiesterase type 5 inhibitors (PDE5-Is), addressing critical issues in their current and future use, assessing unanswered questions, and identifying research needs. METHODS:A MEDLINE search was conducted on PDE5-Is, with emphasis on clinical trials and experience, for interpret...

    journal_title:European urology

    pub_type: 杂志文章,评审

    doi:10.1016/j.eururo.2006.07.020

    authors: Hatzimouratidis K,Hatzichristou D

    更新日期:2007-01-01 00:00:00

  • p53 immunoreactivity as prognostic marker for cancer-specific survival in prostate cancer.

    abstract:OBJECTIVES:The objective of this study was to evaluate the role of p53 immunoreactivity as a prognostic marker in prostate cancer. METHODS:The nuclear accumulation of the aberrant p53 protein was determined by immunohisto-chemistry on surgical specimens and related to stage, grade and cancer-specific survival in 186 p...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000474147

    authors: Stattin P,Bergh A,Karlberg L,Nordgren H,Damber JE

    更新日期:1996-01-01 00:00:00

  • A novel model of urinary tract differentiation, tissue regeneration, and disease: reprogramming human prostate and bladder cells into induced pluripotent stem cells.

    abstract:BACKGROUND:Primary culture and animal and cell-line models of prostate and bladder development have limitations in describing human biology, and novel strategies that describe the full spectrum of differentiation from foetal through to ageing tissue are required. Recent advances in biology demonstrate that direct repro...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1016/j.eururo.2013.03.054

    authors: Moad M,Pal D,Hepburn AC,Williamson SC,Wilson L,Lako M,Armstrong L,Hayward SW,Franco OE,Cates JM,Fordham SE,Przyborski S,Carr-Wilkinson J,Robson CN,Heer R

    更新日期:2013-11-01 00:00:00

  • Intratesticular effects of cisplatin-based chemotherapy.

    abstract::The question is addressed whether cisplatin-based chemotherapy for germ cell cancer has the same efficacy in intratesticular and in extragonadal sites. For this purpose, 7 patients with germ cell cancer, aged 16-35 years were analysed. Four of the patients had palpable testicular tumors, 3 had occult testicular tumors...

    journal_title:European urology

    pub_type: 杂志文章

    doi:10.1159/000475015

    authors: Dieckmann KP,Loy V

    更新日期:1995-01-01 00:00:00