Abstract：
:A growing body of literature suggests that the experience of clinical pain differs across ethnocultural groups. Additionally, some evidence indicates greater sensitivity to experimentally induced pain among African Americans; however, most studies have included only one pain modality. This study examined ethnic differences in responses to multiple experimental pain stimuli, including heat pain, cold pressor pain, and ischemic pain. Heat pain threshold and tolerance, ratings of repetitive suprathreshold heat, and ischemic and cold pressor pain threshold and tolerance were assessed in 120 (62 African American, 58 white) healthy young adults. Also, several psychological instruments were administered. No ethnic group differences emerged for threshold measures, but African Americans had lower tolerances for heat pain, cold pressor pain and ischemic pain compared to whites. Ratings of intensity and unpleasantness for suprathreshold heat stimuli were significantly higher among African Americans. African Americans reported greater use of passive pain coping strategies and higher levels of hypervigilance. Controlling for passive pain coping did not account for group differences in pain responses, while controlling for hypervigilance rendered group differences in heat pain tolerance and ischemic pain tolerance non-significant. These findings demonstrate differences in laboratory pain responses between African Americans and whites across multiple stimulus modalities, and effect sizes for these differences in pain tolerance were moderate to large for suprathreshold measures. Hypervigilance partly accounted for group differences. Additional research to determine the mechanisms underlying these effects is warranted.
journal_name
Painjournal_title
Painauthors
Campbell CM,Edwards RR,Fillingim RBdoi
10.1016/j.pain.2004.08.013keywords:
subject
Has Abstractpub_date
2005-01-01 00:00:00pages
20-6issue
1-2eissn
0304-3959issn
1872-6623pii
S0304-3959(04)00388-4journal_volume
113pub_type
杂志文章相关文献
PAIN文献大全abstract：:The relation between personality characteristics and the psychological functioning of headache patients has long been a topic of interest. Early investigations focused on clinical and anecdotal reports while recent research has moved toward a more objective evaluation of headache groups by using the MMPI. However, the...
journal_title：Pain
pub_type： 杂志文章,评审
doi：10.1016/0304-3959(86)90037-0
更新日期：1986-02-01 00:00:00
abstract：:Changes in perception of pure thermal stimuli delivered to the hand at threshold intensity were observed during ischemic nerve block in 27 healthy subjects in order to study the significance of unmyelinated cutaneous cold receptors for thermal sensibility. Paresthesias and an increasing feeling of numbness were follow...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(84)90112-X
更新日期：1984-12-01 00:00:00
abstract：:The present paper describes the pain reducing effect of high and low frequency transcutaneous electrical nerve stimulation (TENS) and 100 Hz mechanical vibratory stimulation as compared to placebo stimulation of the HoKu point in 50 patients suffering acute oro-facial pain. Ten of the 30 patients receiving actual stim...
journal_title：Pain
pub_type： 临床试验,杂志文章
doi：10.1016/0304-3959(85)90100-9
更新日期：1985-11-01 00:00:00
abstract：:Blockade of the noradrenergic input to the nucleus raphe magnus (NRM) by the injection of alpha-adrenergic antagonists produces hypoalgesia. Previous studies show that this hypoalgesia is blocked by the intrathecal injection of either phentolamine or methysergide. The present study demonstrates that depletion of spina...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(83)90113-6
更新日期：1983-07-01 00:00:00
abstract：:The neurochemical effects of adenosine signaling in small-fiber neuropathy leading to neuropathic pain are yet to be explored in a direct manner. This study examined this system at the level of ligand (through the ectonucleotidase activity of prostatic acid phosphatase [PAP]) and adenosine A1 receptors (A1Rs) in resin...
journal_title：Pain
pub_type： 杂志文章
doi：10.1097/j.pain.0000000000001246
更新日期：2018-08-01 00:00:00
abstract：:Patients with schizophrenia report reduced pain sensitivity in clinical studies, but experimental studies are required to establish pain sensitivity as a potential endophenotype. We conducted a systematic review of electronic databases from database inception until April 15, 2015, including experimental studies invest...
journal_title：Pain
pub_type： 杂志文章,meta分析
doi：10.1097/j.pain.0000000000000304
更新日期：2015-11-01 00:00:00
abstract：:The existence of prostaglandin (PG) receptors in the spinal cord has been demonstrated, but their role in sensory processing is not yet well defined. PGE1 is widely used clinically as a vasodilator. The present study was designed to investigate the effects of intrathecally administered PGE1 on the transmission of diff...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(95)00055-0
更新日期：1995-12-01 00:00:00
abstract：:Chronic pain due to surgery, radiotherapy, or chemotherapy is prevalent in long-term cancer survivors. Chronic pain due to successful cancer treatment should be treated as chronic nonmalignant pain, primarily with nonpharmacological strategies. Based on complete national data from the Cancer Registry of Norway and the...
journal_title：Pain
pub_type： 杂志文章
doi：10.1097/j.pain.0000000000001459
更新日期：2019-04-01 00:00:00
abstract：:Chronic or episodic severe itch is recurrent in atopic dermatitis (AD). Nonhistaminergic itch pathways are suggested to dominate in AD itch, contributing to an "itch-scratch-itch cycle" that prolongs and worsens itch, pain, and skin lesions. We hypothesized that nonhistaminergic neuronal sensitization contributes to i...
journal_title：Pain
pub_type： 杂志文章
doi：10.1097/j.pain.0000000000000980
更新日期：2017-09-01 00:00:00
abstract：:The efficacy of amitriptyline was evaluated in 28 patients with chronic oral-facial pain. Most of the patients had evidence of musculoskeletal pain while some had a history suggesting pain of neurogenic origin. Two patients had mixed elements of neurogenic and musculoskeletal pain. Amitriptyline was more effective tha...
journal_title：Pain
pub_type： 临床试验,杂志文章
doi：10.1016/0304-3959(87)90036-4
更新日期：1987-11-01 00:00:00
abstract：:On a no treatment trial, a group of 24 oriental subjects rated cold pressor pain as significantly more painful and distressing than did a group of 24 occidental subjects. For half of the Orientals and half of the Occidentals, a second trial was conducted after acupuncture analgesia had been induced. The remaining 12 O...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(77)90086-0
更新日期：1977-10-01 00:00:00
abstract：:To characterize the contribution of interleukin-6 (IL-6) to spinal cord injury pain (SCIP), we employed a clinically relevant rat contusion model of SCIP. Using Western blots, we measured IL-6 levels in lumbar segments (L1-L5), at the lesion site (T10), and in the corresponding lumbar and thoracic dorsal root ganglia ...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2013.03.026
更新日期：2013-07-01 00:00:00
abstract：:Several studies have implicated a potential role for histamine H(3) receptors in pain processing, although the data are somewhat conflicting. In the present study we investigated the effects of the novel potent and highly selective H(3) receptor antagonists GSK189254 (6-[(3-cyclobutyl-2,3,4,5-tetrahydro-1H-3-benzazepi...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2007.11.006
更新日期：2008-08-15 00:00:00
abstract：:Morphine (M) and hydromorphone (HM) are commonly used opioid analgesics for cancer pain. Opioid rotation is often necessary in the event of toxicity and/or inadequate analgesia. Equianalgesic reference tables based on single dose comparisons are possibly inadequate for patients on chronic treatment and developing tole...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/s0304-3959(97)00018-3
更新日期：1997-08-01 00:00:00
abstract：:Both physicians and nurses are responsible for adequate pain management. The aim of this study was to assess pain management behavior of physicians and nurses, and to evaluate the effects of a Pain Monitoring Program for nurses on the extent to which nurses administer analgesics. The Pain Monitoring Program consisted ...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/S0304-3959(00)00344-4
更新日期：2000-12-15 00:00:00
abstract：:A randomized, double-blind, placebo-controlled study of low-level laser therapy (LLLT) in 90 subjects with chronic neck pain was conducted with the aim of determining the efficacy of 300 mW, 830 nm laser in the management of chronic neck pain. Subjects were randomized to receive a course of 14 treatments over 7 weeks ...
journal_title：Pain
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/j.pain.2006.05.018
更新日期：2006-09-01 00:00:00
abstract：:Injured afferent neurons produce spontaneous activity that is generated away from the normal impulse generation site. Since this activity, referred to as ectopic discharges, may play a significant role in neuropathic pain, it is important to systematically analyze the activity in various pain states. The present study...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/s0304-3959(99)00219-5
更新日期：2000-02-01 00:00:00
abstract：:The antinociception effect of clomipramine and the combination of clomipramine and morphine was evaluated using the constant temperature hot plate test, the increasing temperature hot plate test and the formalin test in mice. Both a single dose of clomipramine (10 mg/kg) given intraperitoneally (i.p.) and chronic clom...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(88)90295-3
更新日期：1988-06-01 00:00:00
abstract：:Neuropathic pain behaviour is not observed in neonatal rats and tactile allodynia does not develop in the spared nerve injury (SNI) model until rats are 4 weeks of age at the time of surgery. Since activated spinal microglia are known to play a key role in neuropathic pain, we have investigated whether the microglial ...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2006.09.018
更新日期：2007-04-01 00:00:00
abstract：:This study focuses on changes in adrenergic sensitivity in untransected sensory axons that innervate an area of skin made neuropathic by transection of neighboring nerves. The segmental nerve injury model is favorable for this since all axons in the L5 and L6 nerves are transected whereas the L4 axons are intact. Earl...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/S0304-3959(98)00252-8
更新日期：1999-04-01 00:00:00
abstract：:It has been suggested that a number of peptides may be involved in the transmission of pain. In order to evaluate the possible role of peptides in the development of headache, we have, in the present study, examined the presence of nerve fibres containing neuropeptide Y (NPY), vasoactive intestinal peptide (VIP), subs...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(86)90162-4
更新日期：1986-12-01 00:00:00
abstract：:A cold pressor task (CPT) was used with 203 college students (112 women and 91 men) in a study of sex differences in pain response. Physiological measures were taken before and after pain induction, and sex-differentiating personality traits were assessed with the Personal Attributes Questionnaire (PAQ). The Pain Cata...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2004.08.017
更新日期：2004-11-01 00:00:00
abstract：:Persistent Idiopathic Facial Pain (PIFP) is a poorly understood chronic pain syndrome of the face, formerly known as atypical facial pain. It is characterized by a constant painful sensation without neurological abnormalities and without clinically objectifiable cause. Similarities to neuropathic pain conditions have ...
journal_title：Pain
pub_type： 杂志文章
doi：10.1097/j.pain.0000000000002126
更新日期：2020-10-26 00:00:00
abstract：:The blood vessels and the pial surface of the brain, spinal cord and its roots are innervated by primary afferent neurones. Here, we have electrophysiologically characterized the functional properties of a subpopulation of these afferent fibres that supply the ventral roots of the cat sacral spinal cord. We have taken...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(91)90167-V
更新日期：1991-04-01 00:00:00
abstract：:Plastic changes in the anterior cingulate cortex (ACC) are critical in pain hypersensitivity caused by peripheral nerves injury. The Notch signaling pathway has been shown to regulate synaptic differentiation and transmission. Therefore, this study was to investigate the function of the Notch signaling pathway in the ...
journal_title：Pain
pub_type： 杂志文章
doi：10.1097/j.pain.0000000000002014
更新日期：2021-01-01 00:00:00
abstract：:We investigated the question of how cultural and linguistic backgrounds affect relationships among ratings (reported by patients with metastatic cancer) of pain's interference with such functions as activity, mood, and sleep. Multidimensional scaling (MDS) was used to analyze ratings of pain interference from a sample...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(96)03131-4
更新日期：1996-10-01 00:00:00
abstract：:Clinicians use patients' recall of pain and disability relief as indicators of therapeutic effectiveness. Recall can change over time, however, and is influenced by factors other than true relief, including current health status. We have determined the trend in the relative contribution of current pain/disability and ...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/s0304-3959(01)00377-3
更新日期：2002-01-01 00:00:00
abstract：:Sensory neuron-specific receptors (SNSRs) belong to a large family of GPCRs, known as Mrgs (Mas-related genes), many of which are preferentially expressed in primary afferent nociceptors. Selective SNSR agonists produce pain-like behaviors in rats, showing that SNSR activation is sufficient to produce pain. However, i...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/j.pain.2009.02.010
更新日期：2009-05-01 00:00:00
abstract：:In the present study 366 patients suffering acute or chronic musculoskeletal pain of different origin were given vibratory stimulation for the pain. Many of the patients had previously had treatments of various kinds without satisfactory relief. The effect of vibratory stimulation was assessed during and after stimula...
journal_title：Pain
pub_type： 杂志文章
doi：10.1016/0304-3959(84)90808-X
更新日期：1984-09-01 00:00:00
abstract：:Potential applications of attention bias modification (ABM) for acute and chronic pain patients are investigated. In study 1, 54 acute back pain patients (46 of whom completed the study) were recruited at their initial physiotherapy session and randomised to receive 1 session of ABM or placebo. Patients were followed ...
journal_title：Pain
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.pain.2011.12.014
更新日期：2012-03-01 00:00:00
