Abstract：
:Node dissection for melanoma remains the most important therapeutic decision for the optimal management of the patient with melanoma. In Australia and in some parts of the United States, the majority of patients with intermediate thickness melanoma (1.6-4.00 mm) will undergo elective lymph node dissection. In Europe, the majority of patients with similar lesions are treated with wide local excision only. The development of an agreed policy for node dissection for melanoma awaits the results of 2 current, prospective randomized trials confirming or disproving the efficacy of elective lymph node dissection. Non-randomized studies showing a benefit or not showing a benefit are readily available but the only 2 prospective randomized studies published to date showing a benefit, have been criticized on methodologic grounds. This paper summarizes the evidence and opinions on both sides of this debate. The clinician charged with responsibility for this important decision must, as yet, make the decision to dissect lymph nodes on the basis of a perspective derived from the best available evidence.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
McCarthy WH,Shaw HM,Cascinelli N,Santinami M,Belli Fkeywords:
subject
Has Abstractpub_date
1992-03-01 00:00:00pages
203-13issue
2eissn
0364-2313issn
1432-2323journal_volume
16pub_type
杂志文章,评审abstract：BACKGROUND:Chronic pilonidal disease is a debilitating condition that typically affects young adults. There is a wide variety of available therapeutic strategies reflecting the inconsistent outcomes attributed to the various operative approaches. The majority involve excision of the sinus tract followed by either prima...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-011-1138-z
更新日期：2011-08-01 00:00:00
abstract：:We evaluated the morbidity associated with primary closure by interrupted subcuticular absorbable sutures following emergency appendectomy. In a prospective clinical trial over a 12-month period, 216 children who underwent emergency appendectomy had skin closure using subcuticular interrupted absorbable polyglactin 4-...
journal_title：World journal of surgery
pub_type： 临床试验,杂志文章
doi：10.1007/s002689900007
更新日期：1996-01-01 00:00:00
abstract：BACKGROUND:The present study was designed to evaluate the relationship between preoperative Toll-like receptor (TLR) expression in peripheral blood monocytes (PBMC) and the postoperative inflammatory cytokine secretion from PBMC, as well as the postoperative infectious complications in patients with gastrointestinal ca...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0839-z
更新日期：2011-02-01 00:00:00
abstract：BACKGROUND:The aim of the present study was to evaluate the efficacy of cholestyramine ointment (15 %) in reducing postoperative pain at rest and during defecation after open hemorrhoidectomy. METHODS:A total of 91 patients with third and fourth degree hemorrhoids undergoing open hemorrhoidectomy were included in this...
journal_title：World journal of surgery
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00268-012-1895-3
更新日期：2013-03-01 00:00:00
abstract：BACKGROUND:Restless legs syndrome (RLS) is a common and poorly understood movement disorder that leads to unpleasant leg sensations. Although RLS can be idiopathic, secondary etiologies such as iron deficiency and renal failure are common. The aim of this prospective cohort study was to evaluate whether RLS is a common...
journal_title：World journal of surgery
pub_type： 临床试验,杂志文章
doi：10.1007/s00268-013-2185-4
更新日期：2013-12-01 00:00:00
abstract：BACKGROUND:Abdominal compartment syndrome (ACS) is a difficult entity with two main problems during its course: (1) survival of the patient during the early period and (2) closure of the open wounds during the late period. In this study we evaluated the decision to decompress according to the level of intraabdominal pr...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-007-9286-x
更新日期：2008-01-01 00:00:00
abstract：:A new technique utilizing miniaturized (2 mm) instrumentation to perform laparoscopic cholecystectomy (LC) is introduced. The safety and efficacy of this mini-LC were assessed. Fifty consecutive mini-LCs were performed using one 10-mm port and three 2-mm ports (cumulative port size 16 mm). A 2-mm fiberoptic video-lapa...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/pl00013163
更新日期：1999-02-01 00:00:00
abstract：BACKGROUND:Anal manometry is a useful tool for testing the effectiveness of surgical treatment. However, most techniques for anal pressure measurement are not easily available because of high cost. The aim of the present study was to introduce an easy and reproducible method for measuring anal pressures in testing the ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-006-0365-1
更新日期：2007-02-01 00:00:00
abstract：:The geographic distribution of duodenal ulcer and its characteristics in rural areas of high incidence in developing countries are reviewed. The choice of surgical procedures is discussed in light of the bulky diet and nutritional problems of these countries. A vagotomy procedure is advised for duodenal ulcer and a B...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF01654731
更新日期：1977-01-01 00:00:00
abstract：INTRODUCTION:Response rates to systemic chemotherapy for patients who have failed irinotecan-based chemotherapy for liver-dominant metastatic colorectal cancer range between 10 and 18 % with overall survival between 7 and 9 months. The aim of this study was to assess the efficacy and safety of hepatic arterial irinotec...
journal_title：World journal of surgery
pub_type： 杂志文章,多中心研究
doi：10.1007/s00268-015-3386-9
更新日期：2016-05-01 00:00:00
abstract：:Patients with short bowel syndrome (SBS) receiving total parenteral nutrition (TPN) have a high incidence of catheter-related sepsis, one of its major complications. The aim of this study was to correlate the length of remaining small bowel (RSB) with septic episodes related to the central venous catheter in a group o...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002680010274
更新日期：2000-12-01 00:00:00
abstract：BACKGROUND:Postoperative ascites (POA) is a common complication after liver resection (LR). The aim of the present study was to identify the risk factors for developing POA and to evaluate its clinical significance in the prognosis of patients with hepatocellular carcinoma (HCC). METHODS:We performed a retrospective a...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-011-1367-1
更新日期：2012-02-01 00:00:00
abstract：BACKGROUND:The treatment of acute limb ischemia (ALI) has barely changed over the last years. However, the progressive implementation of anticoagulants, antiplatelet agents or statins within the population might have modified the profile and prognosis of patients suffering an ALI. The aim of this study was to evaluate ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-4511-3
更新日期：2018-08-01 00:00:00
abstract：BACKGROUND:Open surgical cricopharyngeal myotomy(CM) is considered standard of care for Zenker's diverticulum(ZD). Trans-oral CM has been described using a rigid stapling device for two decades; however, this remains problematic for severely kyphotic patients. This problem can be overcome with flexible endoscopy utiliz...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3442-0
更新日期：2016-06-01 00:00:00
abstract：:Postoperative complications in patients with obstructive jaundice remain increased when associated with endotoxemia and the inflammatory response due to gut barrier failure. Administration of glutamine has been proposed to maintain the integrity of the gut mucosa and thus reduce bacterial translocation (BT), but the e...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-7721-4
更新日期：2005-10-01 00:00:00
abstract：INTRODUCTION:Preventing secondary insult to the brain is imperative following traumatic brain injury (TBI). Although TBI does not preclude nonoperative management (NOM) of splenic injuries, development of hypotension in this setting may be detrimental and could therefore lead trauma surgeons to a lower threshold for op...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-4494-0
更新日期：2018-08-01 00:00:00
abstract：BACKGROUND:Laparoscopic hepatectomy (LH) is established as a safe and feasible treatment option for liver tumors. However, whether the adoption of laparoscopic approach for malignant tumors, such as hepatocellular carcinoma (HCC), will compromise the long-term result is still unknown. This study was designed to evaluat...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-011-1212-6
更新日期：2011-10-01 00:00:00
abstract：:A total of 143 patients who underwent hepatic resection for hepatocellular carcinoma in our department were reviewed. The review was conducted for two periods: 1970-1982 (early period) and 1983-1990 (late period), that is, the periods before and after introduction of the hepatic surgical technique involving the use of...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF01659138
更新日期：1993-09-01 00:00:00
abstract：:This study was conducted retrospectively to examine the efficacy of Traverso reconstruction compared with Billroth I reconstruction after pylorus-preserving pancreaticoduodenectomy, in the prevention of several complications. Pylorus-preserving pancreaticoduodenectomy is an aggressive surgery, and insufficiency of the...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-7697-0
更新日期：2005-07-01 00:00:00
abstract：BACKGROUND:Scarce data are available on the characteristics of postoperative organ failure (POF) and mortality after gastrectomy. We aimed to describe the causes of organ failure and mortality related to gastrectomy for gastric cancer and to identify patients with POF who are at a risk of failure to rescue (FTR). METH...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-020-05382-9
更新日期：2020-05-01 00:00:00
abstract：:There are three basic roles of laparoscopic surgery for patients with colorectal cancer. First, although infrequently needed prior to therapy, diagnostic or staging laparoscopy may be valuable in certain colorectal cancer patients. Second, the laparoscopic approach may offer several attractive features for the palliat...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s002689900294
更新日期：1997-09-01 00:00:00
abstract：:This article surveys in an interdisciplinary fashion the evolution of ancient Greek medicine and traumatology in particular. In sounding out the key methods and themes of Greek medicine, we cite a range of medical treatises and correlate them to the rich evidence of ancient Greek art (iconography), which often is expl...
journal_title：World journal of surgery
pub_type： 历史文章,杂志文章
doi：10.1007/s00268-003-6931-x
更新日期：2004-04-01 00:00:00
abstract：BACKGROUND:Splenic trauma is a common organ injury following blunt abdominal trauma. In order to establish the contemporary epidemiology of blunt splenic trauma in Scotland and to detect risk factors associated with patient outcomes, analysis of a multi-center database of trauma patients was performed. METHODS:The stu...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-007-9218-9
更新日期：2007-11-01 00:00:00
abstract：BACKGROUND:This study was designed to establish the current demographic and treatment patterns of mandibular fractures in two urban centers (Lagos University Teaching Hospital, Lagos, and National Hospital, Abuja) in Nigeria. METHODS:All cases of mandibular fractures diagnosed and treated at the Department of Oral and...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-008-9773-8
更新日期：2008-12-01 00:00:00
abstract：BACKGROUND:Approximately half of trauma patients develop post-traumatic depression. It is suggested that beta-blockade impairs trauma memory recollection, reducing depressive symptoms. This study investigates the effect of early beta-blockade on depression following severe traumatic injuries in patients without signifi...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-017-3935-5
更新日期：2017-07-01 00:00:00
abstract：:Some 25%-70% of sporadic medullary thyroid carcinomas (MTCs) are associated with somatic mutations within the RET proto-oncogene. In a significant number of MTCs, however, no such genetic variations can be detected, which implies alternative pathogenic molecular alterations. To assess altered RET mutation-specific gen...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-004-7748-y
更新日期：2005-04-01 00:00:00
abstract：BACKGROUND:Variously described as Courvoisier's law, sign, or even gallbladder, this eponymous "law" has been taught to medical students since the publication of Courvoisier's treatise in 1890. METHODS:We reviewed Courvoisier's original "law," the modern misconceptions surrounding it, and the contemporary evidence sup...
journal_title：World journal of surgery
pub_type： 传,历史文章,杂志文章
doi：10.1007/s00268-008-9908-y
更新日期：2009-04-01 00:00:00
abstract：BACKGROUND:Complications are important indicators of immediate postoperative outcomes. The Clavien-Dindo classification (CDC) is a widely used index for the classification of surgical complications. More recently, the comprehensive complication index (CCI) has also been introduced for classifying postoperative complica...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-020-05859-7
更新日期：2021-03-01 00:00:00
abstract：BACKGROUND:Surgical site infection (SSI) is a common cause of major morbidity after liver resection. This study aimed to identify the risk factors for incisional and organ/space SSIs after liver resection. METHODS:Our liver surgery database was retrospectively analyzed for patients treated between January 2009 and Nov...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-014-2922-3
更新日期：2015-05-01 00:00:00
abstract：BACKGROUND:Human factors research has suggested benefits of consistent teams yet no surgical team consistency measures have been established for teamwork improvement initiatives. METHODS:Retrospective analysis was conducted of teams performing consecutive elective procedures of unilateral primary total knee and hip re...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-014-2866-7
更新日期：2015-04-01 00:00:00
