Abstract:
BACKGROUND:Restless legs syndrome (RLS) is a common and poorly understood movement disorder that leads to unpleasant leg sensations. Although RLS can be idiopathic, secondary etiologies such as iron deficiency and renal failure are common. The aim of this prospective cohort study was to evaluate whether RLS is a common feature in patients undergoing parathyroidectomy for renal hyperparathyroidism (rHPT) and if RLS-related symptoms can be influenced by surgery. METHODS:After providing written consent, patients who underwent a parathyroidectomy for rHPT between January and November 2011 answered a validated RLS-screening-questionnaire (RLSSQ). If this was suggestive for RLS a confirming questionnaire (IRLS) was also completed on the day before surgery, on the fifth postoperative day, and again during follow-up (minimum 12 months). Perioperative parathyroid hormone and calcium levels, as well as the scores of the questionnaires were analyzed. RESULTS:Twenty-one patients (14 men, 7 women) with a mean age of 47.8 ± 3.2 years underwent total parathyroidectomy with bilateral cervical thymectomy and parathyroid autotransplantation for rHPT. The mean score of the RLSSQ of all 21 patients prior to operation was 6.1 ± 0.5. In 10 of 21 patients (47.6 %) the results of the RLSSQ were suggestive for RLS with a mean score of 8.0 ± 0.3. The consecutive scores of the IRLS in these latter patients significantly dropped from 26.6 ± 1.4 to 19.0 ± 2.2 between the preoperative and postoperative settings (p < 0.05). After a mean follow-up of 17.3 ± 3.7 months the mean scores of the RLSSQ and the IRLS were 6.1 ± 0.6 and 16.3 ± 1.8. CONCLUSIONS:rHPT may play a major role in the severity of RLS-associated symptoms in patients with renal failure. Consequently, parathyroidectomy may prove to be a valuable tool to reduce RLS-associated morbidity in affected patients. However, larger prospective trials are required to confirm the possible relation between RLS and rHPT seen in the present study
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Schneider R,Karakas E,Bartsch DK,Schlosser Kdoi
10.1007/s00268-013-2185-4subject
Has Abstractpub_date
2013-12-01 00:00:00pages
2866-71issue
12eissn
0364-2313issn
1432-2323journal_volume
37pub_type
临床试验,杂志文章abstract:BACKGROUND:Spleen-preserving procedures deserve every effort by surgeons to reduce the risk of overwhelming postsplenectomy infection. Partial splenectomy at hospitals with restricted sources remains technically demanding. We describe our method of partial splenectomy for benign splenic cysts with the aid of a Lin clam...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-007-9240-y
更新日期:2007-11-01 00:00:00
abstract::Cardiovascular disease [atherosclerosis and subsequent myocardial infarction (MI)] has been associated with primary hyperparathyroidism. We aimed at studying cardiovascular events before and after surgery and mortality after surgery for primary hyperparathyroidism using a historical follow-up design. A total of 674 pa...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-002-6541-z
更新日期:2003-02-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/BF00295930
更新日期:1995-09-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章,评审
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journal_title:World journal of surgery
pub_type: 杂志文章
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-020-05571-6
更新日期:2020-09-01 00:00:00
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journal_title:World journal of surgery
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doi:10.1007/s00268-004-7290-y
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journal_title:World journal of surgery
pub_type: 杂志文章,评审
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-016-3563-5
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journal_title:World journal of surgery
pub_type: 杂志文章
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更新日期:2012-06-01 00:00:00
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journal_title:World journal of surgery
pub_type: 临床试验,杂志文章
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更新日期:1994-11-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-010-0412-9
更新日期:2010-06-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002689900418
更新日期:1998-05-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-007-9267-0
更新日期:2007-12-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-009-0319-5
更新日期:2010-04-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s00268-015-3019-3
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:The aim of this study was to evaluate and investigate the complications of carotid endarterectomy (CEA) and carotid artery stenting (CAS) by performing a meta-analysis based on prospective randomized controlled trials (RCTs). METHODS:We performed a search of multiple electronic databases for RCTs containing...
journal_title:World journal of surgery
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s00268-008-9862-8
更新日期:2009-03-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-017-4423-7
更新日期:2018-07-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
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更新日期:2005-06-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-0440-z
更新日期:2006-07-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/pl00013179
更新日期:1999-03-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-014-2879-2
更新日期:2015-03-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
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更新日期:1992-07-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002689900508
更新日期:1998-09-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章,已发布勘误
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更新日期:2020-06-01 00:00:00
abstract::Gastric cancer is a disease in which the main treatment is surgical extirpation. The modifications introduced in the surgical treatment over the last decades were accompanied by a clear increase of survival, which reaches global values of 61% at 5 years in Japan. One of the reasons that contribute to this improvement ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-001-0228-8
更新日期:2002-03-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-010-0473-9
更新日期:2010-07-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
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更新日期:2019-11-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
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更新日期:2015-05-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章,评审
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