Abstract:
BACKGROUND:Retroperitoneal soft tissue sarcomas (RSTS) are a rare and uncommon entity with a poor 5-year overall survival (OS) of approximately 50%, even though they rarely metastasize. The aim of the present study was to analyze the survival of patients with RSTS treated at our institution. PATIENTS AND METHODS:Patients with RSTS treated between 1990 and 2008 were included. Variables analyzed were age, sex, histological type, TNM stage, tumor size, grade of differentiation, and treatment (surgery, chemotherapy only, radiotherapy only, adjuvant radiotherapy, and best supportive care). R0, R1, and R2 resection were analyzed. Overall survival, recurrence-free survival (RFS), cancer-specific survival (CSS), and survival comparison by stage, grade, and type of resection were analyzed. RESULTS:Data for 46 patients were analyzed, 20 men and 26 women. Median age was 51.1 years. Surgery with a curative intent was performed in 32 patients, and R0 resection was feasible in 19 (59.4%). The 5- and 10-year OS rates were 47 and 30%, respectively, for the entire group. The median CSS for resected patients was 102 months; the 5-year OS for stages I, III, and IV was 83, 37, and 0%, respectively; the 5-year OS for low histological grade disease and high histological grade disease was 82 and 35%, respectively; and for R0, R1, and R2 resection, the 5-year OS was 81, 56, and 14%, respectively. Median RFS was 79 months. CONCLUSIONS:Incomplete surgical resection, unresectable disease, high histological grade, and advanced TNM stage are associated with a poor survival in patients with RSTS. Complete resection is still the treatment of choice.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
García-Aceituno L,Villarreal-Garza C,Perfecto M,León-Rodríguez Edoi
10.1007/s00268-010-0473-9subject
Has Abstractpub_date
2010-07-01 00:00:00pages
1511-6issue
7eissn
0364-2313issn
1432-2323journal_volume
34pub_type
杂志文章abstract:BACKGROUND:We hypothesized that a dedicated collaborative transdisciplinary Geriatric Surgery Service (GSS) will improve care for elderly colorectal surgery patients. METHODS:Patients older than 75 years of age who underwent major colorectal surgery were included in this study. The Geriatric Surgery Service employed a...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-011-1112-9
更新日期:2011-07-01 00:00:00
abstract::Surgical management of hepatic hydatid disease has been associated with an overall local recurrence rate of approximately 10%. Local recurrence is rarely seen following complete resection of an intact cyst and is usually the result of spillage of live parasites or leaving a residual cyst wall containing germinal epith...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s002680020011
更新日期:2001-01-01 00:00:00
abstract::Pancreas transplantation has emerged as the single most effective way to achieve normal glucose homeostasis inpatients with type I insulin-dependent diabetes mellitus. Optimal immunosuppressive strategies for pancreas transplantation continue to evolve with the use of newer, more potent immunosuppressive agents,partic...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-001-0207-0
更新日期:2002-02-01 00:00:00
abstract:BACKGROUND:Linitis plastica-type gastric carcinoma remains a disease with poor prognosis despite an aggressive surgical approach. Although a prominent pattern of disease failure is peritoneal carcinomatosis, some patients experience rapid disease progression without signs of the peritoneal disease. METHODS:Clinicopath...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-008-9672-z
更新日期:2008-09-01 00:00:00
abstract:IMPORTANCE:In resource-limited settings, identification of successful and sustainable task-shifting interventions is important for improving care. OBJECTIVE:To determine whether the training of lay people to take vital signs as trauma clerks is an effective and sustainable method to increase availability of vital sign...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-017-4121-5
更新日期:2017-12-01 00:00:00
abstract::Pectus excavatum (PE) is one of the most common anomalies of childhood. It occurs in approximately 1 in every 400 births, with males afflicted 5 times more often than females. PE is usually recognized in infancy, becomes much more severe during adolescent growth years, and remains constant throughout adult life. Sympt...
journal_title:World journal of surgery
pub_type: 社论,评审
doi:10.1007/s00268-003-7025-5
更新日期:2003-05-01 00:00:00
abstract:BACKGROUND:Adhesions due to the reactions caused by the grafts used in primary vascular operations can lead to various problems when a secondary operation is necessary. These problems include bleeding, injuries to neighboring organs, and complications occurring due to a prolonged operation. We investigated the effects ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-0750-1
更新日期:2006-09-01 00:00:00
abstract:BACKGROUND:The decision to proceed to simple underwater seal drainage or apply active suction to the underwater seal after lung resection is mostly based on surgeon preference. The purpose of this study was to test whether routine application of active suction is necessary after lobectomy. PATIENTS AND METHODS:This wa...
journal_title:World journal of surgery
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00268-008-9741-3
更新日期:2008-11-01 00:00:00
abstract:BACKGROUND:Sepsis is common in surgical patients, and its presence influences the outcomes in those to undergo surgery. Factors such as advanced age, presence of comorbidities and many other conditions increase mortality in surgical patients with sepsis. The sequential organ failure assessment (SOFA) score simplified i...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-020-05708-7
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:There is emerging evidence indicating that distractions in the operating room (OR) are prevalent. Studies have shown a negative impact of distractions, but they have been conducted mostly with residents in simulated environments. We tested the hypothesis that intraoperative distractions are associated with d...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-013-2315-z
更新日期:2014-04-01 00:00:00
abstract:BACKGROUND:Trauma continues to be a major health problem worldwide, particularly in the developing world, with high mortality and morbidity. Yet most developing countries lack an organized trauma system. Furthermore, developing countries do not have in place any accreditation process for trauma centers; thus, no accept...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-014-2538-7
更新日期:2014-08-01 00:00:00
abstract:BACKGROUND:Human factors research has suggested benefits of consistent teams yet no surgical team consistency measures have been established for teamwork improvement initiatives. METHODS:Retrospective analysis was conducted of teams performing consecutive elective procedures of unilateral primary total knee and hip re...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-014-2866-7
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:The objective of this study was to compare the prevalence of Helicobacter pylori (HP) seropositivity in patients undergoing bariatric surgery with that of the general population. METHODS:H. pylori serologies, tested by ELISA, were collected on 240 morbidly obese patients seen at the Cleveland Clinic Florida...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-008-9608-7
更新日期:2008-09-01 00:00:00
abstract::Fifty patients reoperated for failed Nissen fundoplication are presented; 29 patients (group 2) were operated between 1983 and 1988 while 21 patients (group 1) were operated before 1983. In group 1, the "slipped Nissen" had been the most frequent cause of reoperation (48%). In group 2, the most frequent causes for the...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/BF01658439
更新日期:1989-11-01 00:00:00
abstract:BACKGROUND:The use of the Harmonic Scalpel (HS) for cystic duct ligation began with little data about its efficacy or safety. On the other hand, there is not any literature available about the use of PlasmaKinetic Sealer (PK) for closing the cystic duct in laparoscopic cholecystectomy (LC). Therefore, this study was de...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-010-0819-3
更新日期:2011-04-01 00:00:00
abstract::The success of parathyroid surgery is determined by the identification and removal of all parathyroid tumors. Parathyroid tumors accumulate and retain 2-methoxyisobutylisonitrile (MIBI) labeled with technetium-99m. Intravenous injection of this radiopharmacon prior to parathyroid surgery allows identification of parat...
journal_title:World journal of surgery
pub_type: 临床试验,杂志文章
doi:10.1007/s002689900427
更新日期:1998-06-01 00:00:00
abstract:BACKGROUND:Selective nonoperative management (SNOM) of penetrating neck injuries (PNI) has steadily gained favor, but indications for surgery and adjunctive diagnostic studies remain debated. The purpose of the present study is to validate a protocol of SNOM of PNI based on physical examination, which further dictates ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-008-9766-7
更新日期:2008-12-01 00:00:00
abstract::Acute acalculous cholecystitis (AAC) is a well known complication in severely traumatized patients. Existing data of AAC originate from retrospective analyses and episodic case reports. In a prospective study 45 polytraumatized patients admitted to our intensive care unit from January 1989 to June 1990 were clinically...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/BF02067089
更新日期:1992-11-01 00:00:00
abstract:BACKGROUND:PDGFR-β is used as a stromal biomarker and is functional in mesenchymal cells of the tumor microenvironment. The significance of stromal PDGFR-β expression in non-small cell lung cancer (NSCLC) in patients undergoing preoperative chemo- or chemoradiotherapy had not been determined. METHODS:Patients with NSC...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-018-4560-7
更新日期:2018-09-01 00:00:00
abstract:BACKGROUND:The management of positive ductal margins with carcinoma in situ (R1-CIS) after resection is controversial. The aim of this study was to evaluate the impact of R1-CIS on survival in patients who underwent resection for distal cholangiocarcinoma. METHODS:We enrolled 121 consecutive patients with distal chola...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-020-05799-2
更新日期:2021-01-01 00:00:00
abstract:BACKGROUND:Sometimes, it seems to be difficult to preserve the aberrant hepatic artery (HA) during pancreaticoduodenectomy (PD), with respect to en bloc lymph node dissection, especially in the case of aberrant right hepatic artery (RHA). Therefore, we evaluated the influence of incomplete en bloc lymph node (LN) disse...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-009-0063-x
更新日期:2009-08-01 00:00:00
abstract:BACKGROUND:Papillary thyroid carcinoma (PTC) frequently recurs to the lymph nodes, which may not be fatal immediately but is a stressor for physicians and patients. Recurrence to the distant organs, although less frequent, is often life-threatening, and the lung and bone are organs to which PTC is likely to recur. In t...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-012-1423-5
更新日期:2012-06-01 00:00:00
abstract:BACKGROUND:The estimation of physiologic ability and surgical stress (E-PASS) has been used to produce a numerical estimate of expected mortality and morbidity after elective gastrointestinal surgery. The aim of this study was to validate E-PASS in a selected cohort of patients requiring liver resections (LR). METHODS...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-009-9989-2
更新日期:2009-06-01 00:00:00
abstract::Gastric emptying times and symptoms were recorded in 18 patients after total gastrectomy and either a 15-cm J-pouch (n = 10) or a standard esophagojejunal anastomosis (n = 8). A solid test meal labeled with 99mTc was used to compare the emptying times. The postoperative symptoms and nutritional status were also assess...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/BF01659117
更新日期:1993-09-01 00:00:00
abstract:BACKGROUND:A PubMed search of the biomedical literature was carried out to systematically review the role of laparoscopy in colonic diverticular disease. All original reports comparing elective laparoscopic, hand-assisted, and open colon resection for diverticular disease of the colon, as well as original reports evalu...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-012-1872-x
更新日期:2013-03-01 00:00:00
abstract::A variety of techniques have been used for surgical treatment of hepatic hydatid cysts. The objective of this study is to describe the technique of diaphragm myoplasty, and to present our experience in the treatment of selected patients with hydatid disease of the liver by means of this alternative surgical technique....
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-002-6558-3
更新日期:2003-02-01 00:00:00
abstract:BACKGROUND:Intestinal epithelial cell apoptosis has been reported in sepsis as a mechanism of organ failure. The aim of this study was to clarify the role of apoptosis-regulating proteins (bcl-2, bax, cytochrome-c, and caspase-8) in septic rats by studying their expression in gastric and intestinal epithelial cells. M...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-0742-1
更新日期:2007-04-01 00:00:00
abstract::Squamous cell carcinoma of the anus (SCCA) is a rare disease in the average population but is an increasing concern among immunocompromised individuals, such as the HIV-seropositive. Coinfection with human papillomavirus (HPV) in this population is common. HPV infection is difficult to clear with a compromised immune ...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-008-9835-y
更新日期:2009-04-01 00:00:00
abstract:BACKGROUND:Medullary thyroid cancer (MTC) represents the third most common type of thyroid cancer, and the prognosis depends on the stage of the disease at diagnosis and completeness of tumor resection. In 2009, the American Thyroid Association (ATA) published guidelines with evidence-based recommendations for the trea...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-016-3643-6
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:The reported high incidence of 30-60% postoperative pain after an elective day surgical orchidopexy is undesirable. We evaluated the efficacy of our analgesic regimen for unilateral orchidopexy in preschool children performed as a day surgical procedure. METHODS:Between January 2004 and December 2006, 247 c...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-008-9847-7
更新日期:2009-03-01 00:00:00