Inhibition of Helicobacter pylori in vitro by various berry extracts, with enhanced susceptibility to clarithromycin.

abstract：:ANRIL is a long noncoding RNA transcribed from the INK4 locus that encodes three tumor suppressor genes, p15, p16, and ARF. Previous studies demonstrated that ANRIL represses p15 and p16, which positively regulate the pRB pathway, leading to repression of cellular senescence of human normal fibroblasts. However, the r...

journal_title：Molecular and cellular biochemistry

authors： Naemura M,Tsunoda T,Inoue Y,Okamoto H,Shirasawa S,Kotake Y

更新日期：2016-01-01 00:00:00

abstract：:Human glomerular mesangial cells (HMCs) have a finite lifespan and eventually enter irreversible growth arrest known as cellular senescence which is thought to contribute to kidney aging and age-related kidney disorders, such as chronic kidney disease. The signal transducer and activator of transcription 1 (STAT1) is ...

journal_title：Molecular and cellular biochemistry

authors： Jiao S,Meng F,Zhang J,Yang X,Zheng X,Wang L

更新日期：2012-06-01 00:00:00

abstract：:To evaluate the effects of the in vivo endotoxin treatment of the rat on (1) the contractile responses in the subsequently isolated papillary muscle to adrenergic and cholinergic agonists and (2) the biochemical parameters (cyclic GMP, nitric oxide synthesis, protein phosphorylation and ADP-ribosyslation) in the subse...

journal_title：Molecular and cellular biochemistry

authors： Sulakhe PV,Sandirasegarane L,Davis JP,Vo XT,Costain WJ,Mainra RR

更新日期：1996-10-01 00:00:00

abstract：:The flux through the de novo pyrimidine biosynthetic pathway is controlled by the multifunctional protein CAD, which catalyzes the first three steps. The cell cycle dependent regulation of pyrimidine biosynthesis is a consequence of sequential phosphorylation of CAD Thr456 and Ser1406 by the MAP kinase and PKA cascade...

journal_title：Molecular and cellular biochemistry

authors： Kotsis DH,Masko EM,Sigoillot FD,Di Gregorio R,Guy-Evans HI,Evans DR

更新日期：2007-07-01 00:00:00

abstract：:In order to study the mechanism of entry and localization of bilirubin (BR) into cell membrane, binding of BR to sealed and human serum albumin (HSA)-entrapped sealed membranes was studied by CD spectroscopy. An induced bisignate CD cotton effects (CDCEs) of BR-bound sealed membranes were observed with maxima at 515 n...

journal_title：Molecular and cellular biochemistry

authors： Rashid H,Khan MM,Tayyab S

更新日期：2005-09-01 00:00:00

abstract：:Susceptibility of four major rat tissues to oxidative damage in terms of lipid peroxidation induced by in vitro by ascorbate-Fe2+ in homogenates and mitochondria has been examined. Lipid peroxidation, as assessed by thiobarbituric acid reactive substances (TBARS) and conjugated dienes was maximum in brain followed by ...

journal_title：Molecular and cellular biochemistry

authors： Pushpendran CK,Subramanian M,Devasagayam TP,Singh BB

更新日期：1998-01-01 00:00:00

abstract：:To help resolve the controversy as to whether or not Na(+)-H+ exchange is functioning during reperfusion of the ischemic myocardium we assessed the effects of dimethylamiloride (DMA, an amiloride analogue possessing selectivity for inhibition of the Na(+)-H+ exchanger) on cardiac function and intracellular pH during i...

journal_title：Molecular and cellular biochemistry

authors： Docherty JC,Yang L,Pierce GN,Deslauriers R

更新日期：1997-11-01 00:00:00

abstract：:The native form of phospholamban is not known and it is presently under debate whether this protein exists as a monomer or an oligomer in cardiac sarcoplasmic reticulum. The currently accepted model for phospholamban is pentameric, based primarily on its behavior in SDS-polyacrylamide gel electrophoresis. In this stud...

journal_title：Molecular and cellular biochemistry

authors： Harrer JM,Kranias EG

更新日期：1994-11-23 00:00:00

abstract：:The present study was aimed to delineate in vivo mechanisms of orally administered fisetin with special reference to mitochondrial dysfunction in lung tissues employing benzo(a)pyrene (B(a)P) as the model lung carcinogen. The recent revival of interest in the study of mitochondria has been stimulated by the evidence t...

journal_title：Molecular and cellular biochemistry

authors： Ravichandran N,Suresh G,Ramesh B,Manikandan R,Choi YW,Vijaiyan Siva G

更新日期：2014-05-01 00:00:00

abstract：:Henna leaf (Lawsonia inermis), commonly known as Mehndi is cultivated throughout India and is a very popular natural dye to color hand and hair. It is an integral part of indigenous culture, and is also known for its medicinal value. The effect of 200 and 400 mg/kg body weight of 80% ethanolic extract of the fresh lea...

journal_title：Molecular and cellular biochemistry

authors： Dasgupta T,Rao AR,Yadava PK

更新日期：2003-03-01 00:00:00

abstract：:Cyclic AMP (300 micron) activates phosphofructokinase from dialyzed haemolysates of mature rat erythrocytes. The main conclusions are: a) Cyclic AMP, at pH 7.1 and low concentrations of fructose-6-phosphate, is able to reverse the inhibition produced by different amounts of ATP (up to 1.5 mM). b) The cyclic nucleotide...

journal_title：Molecular and cellular biochemistry

authors： Pinilla M,Luque J

更新日期：1977-05-03 00:00:00

abstract：:Diabetes mellitus is a serious global health problem, and cardiovascular complications are the major cause of morbidity and mortality in diabetic patients. The chronic effects of neonatal alloxan- (ALX) induced diabetes mellitus on ventricular myocyte contraction and intracellular Ca(2+) transport have been investigat...

journal_title：Molecular and cellular biochemistry

authors： Howarth FC,Hassan Z,Qureshi MA

更新日期：2011-01-01 00:00:00

abstract：:The present study is to investigate the effect and mechanism of action of interleukin (IL)-17A and its receptor IL-17RA on non-small cell lung cancer (NSCLC). A total of 139 NSCLC patients were included in the study. NSCLC tissues and tumor-adjacent tissues were collected from the patients. Human NSCLC cell lines H157...

journal_title：Molecular and cellular biochemistry

authors： Wu Z,He D,Zhao S,Wang H

更新日期：2019-05-01 00:00:00

abstract：:Idiopathic pes equinovarus is a congenital deformity of the foot and lower leg defined as a fixation of the foot in adduction, supination, and varus. Although the pathogenesis of clubfoot remains unclear, it has been suggested that fibroblasts and growth factors are involved. To directly analyze the protein compositio...

journal_title：Molecular and cellular biochemistry

authors： Ošt'ádal M,Eckhardt A,Herget J,Mikšík I,Dungl P,Chomiak J,Frydrychová M,Burian M

更新日期：2015-03-01 00:00:00

abstract：:Calpain inhibitors show the potential to serve as non-surgical alternatives in treating diabetic cataract and other types of these disorders. Here, we have tested the recently developed calpain inhibitor, SJA6017, for its ability to inhibit cataractogenesis in porcine lenses. These lenses were incubated in increasing ...

journal_title：Molecular and cellular biochemistry

authors： Biswas S,Harris F,Singh J,Phoenix DA

更新日期：2004-06-01 00:00:00

abstract：:Inadequate migration and invasion of the trophoblast cells during embryo implantation is one of the reasons for pregnancy-related complications such as intrauterine growth restriction and preeclampsia. In the present study, relevance of WNT ligands and integrins associated with hepatocyte growth factor (HGF)-mediated ...

journal_title：Molecular and cellular biochemistry

authors： Chaudhary P,Malhotra SS,Babu GS,Sobti RC,Gupta SK

更新日期：2019-03-01 00:00:00

abstract：:Cardiac hypertrophy is an independent risk factor in the development of heart failure. However, the cellular mechanisms underlying the transition from compensated hypertrophy to heart failure are incompletely understood. The aim of this study was to investigate changes in myocardial substrate utilisation and function ...

journal_title：Molecular and cellular biochemistry

authors： Akki A,Smith K,Seymour AM

更新日期：2008-04-01 00:00:00

abstract：:Mucus hypersecretion is a major manifestation in patients with chronic inflammatory airway diseases, and MUC5AC protein is a major component of airway mucus. Earlier studies have demonstrated that neutrophil elastase (NE), a serine protease, mainly produced by neutrophils, stimulates the production of MUC5AC from airw...

journal_title：Molecular and cellular biochemistry

authors： Zhong T,Perelman JM,Kolosov VP,Zhou XD

更新日期：2011-12-01 00:00:00

abstract：:Some properties of a submitochondrial cell-free system for protein synthesis are described. The system was prepared from rat liver mitochondria lysed with Triton X-100, and the lysate was characterized by a linear rate of [14C]amino acid incorporation for 15-20 min with subsequent decline in activity. The incorporatio...

journal_title：Molecular and cellular biochemistry

authors： Kisselev OI,Gaitskhoki VS,Neifakh SA

更新日期：1977-02-04 00:00:00

abstract：:Cross-talk between coding RNAs and regulatory non-coding microRNAs, within human genome, has provided compelling evidence for the existence of flexible checkpoint control of T-Cell activation. The present study attempts to demonstrate that the interplay between miR-2909 and its effector KLF4 gene has the inherent capa...

journal_title：Molecular and cellular biochemistry

authors： Kaul D,Malik D,Wani S

更新日期：2019-01-01 00:00:00

abstract：:We examined the Hepatitis C virus (HCV) genome in the myocardium and liver obtained at autopsy from seven patients with HCV-positive liver cirrhosis and hepatocellular carcinoma (HCC) by in situ hybridization and histopathological studies. The HCV virus genome was detected in the myocardium of one patient as well as i...

journal_title：Molecular and cellular biochemistry

authors： Takeda A,Sakata A,Takeda N

更新日期：1999-05-01 00:00:00

abstract：:Frequent abnormalities in 7p12 locus in different tumors like lung cancer candidate this region for novel regulatory elements. MiRNAs as novel regulatory elements encoded within the human genome are potentially oncomiRs or miR suppressors. Here, we have used bioinformatics tools to search for the novel miRNAs embedded...

journal_title：Molecular and cellular biochemistry

authors： Hoballa MH,Soltani BM,Mowla SJ,Sheikhpour M,Kay M

更新日期：2018-07-01 00:00:00

abstract：:Cultured cardiac myocytes were depleted of ATP by incubation with oligomycin (1 mg/ml). Then the ability of the cells to oxidize various substrates and to restore ATP levels was studied. Following ATP depletion, the cells were found to be able to oxidize glucose given alone, but not palmitate. However, with both subst...

journal_title：Molecular and cellular biochemistry

authors： Tirosh R,Mishor T,Pinson A

更新日期：1996-09-20 00:00:00

abstract：:The aim of the work was to study the influence of vaspin on oxidative stress-induced apoptosis of mouse mesenchymal stem cells (MSCs). MSCs originated from bone marrow of C57BL/6 mouse were treated with vaspin and/or H2O2 in a dose-dependent manner. Cellular viability detected by CCK-8 and cell apoptosis studied by fl...

journal_title：Molecular and cellular biochemistry

authors： Zhu X,Zhang L,Chen Y,Chen B,Huang H,Lv J,Hu S,Shen J

更新日期：2019-12-01 00:00:00

abstract：:In this review we analyze the concepts and the experimental data on the mechanisms of the regulation of energy metabolism in muscle cells. Muscular energetics is based on the force-length relationship, which in the whole heart is expressed as a Frank-Starling law, by which the alterations of left ventricle diastolic v...

journal_title：Molecular and cellular biochemistry

authors： Saks VA,Kuznetsov AV,Vendelin M,Guerrero K,Kay L,Seppet EK

更新日期：2004-01-01 00:00:00

abstract：:Cytosolic purine nucleoside phosphorylase (PNPase) is a well known, and described enzyme which exists in a variety of organisms, both procaryotic and eucaryotic. More recently this enzyme was found in bovine liver mitochondria. The mitochondrial purine nucleoside phosphorylase was purified 63 fold and has a molecular ...

journal_title：Molecular and cellular biochemistry

authors： Haag R,Lewis RA

更新日期：1994-06-29 00:00:00

abstract：:The heptahelical lutropin receptor (LHR) signals primarily via the Gs-adenylyl cyclase pathway and undergoes ligand-mediated receptor desensitization and internalization. A loss-of-function rat LHR mutant was recently described in which a single amino acid residue replacement in exoloop 3, K583E, had no effect on huma...

journal_title：Molecular and cellular biochemistry

authors： Bhowmick N,Narayan P,Puett D

更新日期：1998-10-01 00:00:00

abstract：:Stratifin is a member of 14-3-3 protein family, a highly conserved group of proteins constituted by seven isoforms. They are involved in numerous crucial intracellular functions such as cell cycle and apoptosis, regulation of signal transduction pathways, cellular trafficking, cell proliferation and differentiation, c...

journal_title：Molecular and cellular biochemistry

authors： Medina A,Ghaffari A,Kilani RT,Ghahary A

更新日期：2007-11-01 00:00:00

abstract：:The present study was designed to induce massive accumulation of calcium in the myocardium and to evaluate the effect of calcium overload on myocardial contractile function and biochemical activity of cardiac subcellular membranes. Rats were treated with an oral administration of 500,000 units/kg of vitamin D3 for 3 c...

journal_title：Molecular and cellular biochemistry

authors： Takeo S,Tanonaka R,Tanonaka K,Miyake K,Hisayama H,Ueda N,Kawakami K,Tsumura H,Katsushika S,Taniguchi Y

更新日期：1991-10-16 00:00:00

abstract：:The antioxidant efficacy of vitamin E on Perchloroethylene (PER) induced cytotoxicity has been studied in rats. Feeding PER to rats for 42 days using sesame oil as vehicle alters total protein and protein bound carbohydrate components in liver and kidney of experimental animals. Supplementation of vitamin E prevented ...

journal_title：Molecular and cellular biochemistry

authors： Ebrahim AS,Gopalakrishnan R,Murugesan A,Sakthisekaran D

更新日期：1995-03-09 00:00:00