YAPI, a new Yersinia pseudotuberculosis pathogenicity island.

abstract：:An extracellular cytolysin produced by Vibrio metschnikovii was purified by acid precipitation, phenyl-Sepharose CL-4B chromatography, and rechromatography on a phenyl-Sepharose CL-4B column and high-performance liquid chromatography on a Mono Q (anion-exchange) column. The purified cytolysin had a molecular weight of...

journal_title：Infection and immunity

authors： Miyake M,Honda T,Miwatani T

更新日期：1988-04-01 00:00:00

abstract：:A zone of extracellular digestion of the mucin layer around Candida albicans blastoconidia was observed by transmission electron microscopy in the jejunum of mice inoculated intragastrically (G. T. Cole, K. R. Seshan, L. M. Pope, and R. J. Yancey, J. Med. Vet. Mycol. 26:173-185, 1988). This observation prompted the hy...

journal_title：Infection and immunity

authors： Colina AR,Aumont F,Deslauriers N,Belhumeur P,de Repentigny L

更新日期：1996-11-01 00:00:00

abstract：:The possibility that preexisting specific serum antibody could suppress a defined mucosal immune response to a topically applied antigen was studied in rats. Hyperimmune serum antibody induced by parenteral immunization of rats with cholera toxoid markedly suppressed the mucosal immune response to enterically applied ...

journal_title：Infection and immunity

authors： Pierce NF

更新日期：1980-10-01 00:00:00

abstract：:Despite the high prevalence of cutaneous infections, little is known about the role of host immune responsiveness during Staphylococcus aureus dermatitis. We have recently described a murine model of infectious dermatitis induced by superantigen-producing S. aureus. To assess the role of neutrophils in staphylococcal ...

journal_title：Infection and immunity

authors： Mölne L,Verdrengh M,Tarkowski A

更新日期：2000-11-01 00:00:00

abstract：:El Tor and non-O1 strains of Vibrio cholerae were analyzed to determine whether synthesis of secreted hemolysin was influenced by the concentration of iron in the medium. Synthesis of hemolysin was found to be iron regulated in both El Tor and non-O1 isolates. Increased levels of hemolytic activity were detected in su...

journal_title：Infection and immunity

authors： Stoebner JA,Payne SM

更新日期：1988-11-01 00:00:00

abstract：:The superoxide anion (O2-)-generating activity of guinea pig macrophages stimulated by wheat germ agglutinin (WGA), immune complexes, or phorbol myristate acetate (PMA) was studied after short- and long-term exposures of the cells to muramyl dipeptide (MDP) or lipopolysaccharide (LPS). Neither MDP nor LPS alone induce...

journal_title：Infection and immunity

authors： Yagawa K,Kaku M,Ichinose Y,Nagao S,Tanaka A,Tomoda A

更新日期：1984-07-01 00:00:00

abstract：:Previous studies have demonstrated that both Ixodes scapularis saliva and Borrelia burgdorferi antigens modulated lymphokines and monokines in vitro. The studies presented here were designed to delineate the role of I. scapularis and B. burgdorferi in modulation of the host immune response in vivo. Infestation of C3H/...

journal_title：Infection and immunity

authors： Zeidner N,Mbow ML,Dolan M,Massung R,Baca E,Piesman J

更新日期：1997-08-01 00:00:00

abstract：:Under certain circumstances, soluble antigens, particulate antigens, and/or microorganisms have been shown to bind to primate erythrocytes via complement receptor 1 (CR1) in the presence of specific antibodies and complement. This immune adherence reaction, specific for CR1, can lead to neutralization of antigens in t...

journal_title：Infection and immunity

authors： Powers JH,Buster BL,Reist CJ,Martin E,Bridges M,Sutherland WM,Taylor RP,Scheld WM

更新日期：1995-04-01 00:00:00

abstract：:Purified R-28 antigen from an M-protein-poor, R-antigen-rich strain of group A Streptococcus was prepared by sequential treatment of an acid extract of whole cells with ammonium sulfate fractionation and hydroxylapatite (HA) column chromatography. Purified R-28 antigen was eluted only with 0.10 M sodium phosphate, pH ...

journal_title：Infection and immunity

authors： Johnson RH

更新日期：1975-10-01 00:00:00

abstract：:Dialyzable Lawrence-type transfer factor was prepared from the spleen cells of CF1 mice inoculated with Coccidioides immitis- and Candida albicans-killed vaccines and with live Mycobacterium tuberculosis vaccine (BCG). These preparations were shown to transfer antigen-specific cell-mediated immunity to naive mice, as ...

journal_title：Infection and immunity

authors： Rifkind D,Frey JA,Petersen EA,Dinowitz M

更新日期：1977-04-01 00:00:00

abstract：:Escherichia coli strains isolated from newborn infants were injected intraperitoneally into infant rats. Strains possessing the K1 capsular polysaccharide antigen were significantly more virulent than strains lacking this antigen. When 5-day-old animals were injected with 1.2 X 10(1) colony forming units of a K1 E. co...

journal_title：Infection and immunity

authors： Bortolussi R,Ferrieri P,Wannamaker LW

更新日期：1978-11-01 00:00:00

abstract：:The ability of some typical enteropathogenic Escherichia coli (EPEC) strains to adhere to, invade, and increase interleukin-8 (IL-8) production in intestinal epithelial cells in vitro has been demonstrated. However, few studies regarding these aspects have been performed with atypical EPEC (aEPEC) strains, which are e...

journal_title：Infection and immunity

authors： Sampaio SC,Gomes TA,Pichon C,du Merle L,Guadagnini S,Abe CM,Sampaio JL,Le Bouguénec C

更新日期：2009-10-01 00:00:00

abstract：:Adherence of blastoconidia to epidermal corneocytes is an early event in Candida colonization and infection of the skin. Pathogenic species adhere more avidly than nonpathogenic species, transform to hyphal growth, and invade the stratum corneum of the skin. Adherence was studied by scanning electron microscopy of exp...

journal_title：Infection and immunity

authors： Ray TL,Payne CD

更新日期：1988-08-01 00:00:00

abstract：:Vesicular stomatitis virus (Indiana strain) will only grow in T lymphocytes which have been stimulated to undergo cell division. Evidence is presented that a considerable enrichment of the vesicular stomatitis virus-replicating T cells may be accomplished in the mouse spleen by passing the spleen cells over glass wool...

journal_title：Infection and immunity

authors： Webb DR,Munshi S,Banerjee AK

更新日期：1981-04-01 00:00:00

abstract：:Infection with highly pathogenic Streptococcus suis can cause septic shock, which is characterized by high levels of inflammatory cytokines and a high mortality rate. Our previous study indicated that TREM-1 (triggering receptor expressed on myeloid cells 1) was upregulated in swine spleen cells in response to S. suis...

journal_title：Infection and immunity

authors： Yang C,Chen B,Zhao J,Lin L,Han L,Pan S,Fu L,Jin M,Chen H,Zhang A

更新日期：2015-08-01 00:00:00

abstract：:The 54-kDa extracellular metalloprotease ZapA is an important virulence factor of uropathogenic Proteus mirabilis. While ZapA has the ability to degrade host immunoglobulins (Igs), the dramatic attenuation of virulence in ZapA mutants suggests that this enzyme may have a broader spectrum of activity. This hypothesis w...

journal_title：Infection and immunity

authors： Belas R,Manos J,Suvanasuthi R

更新日期：2004-09-01 00:00:00

abstract：:In an Escherichia coli strain of human origin, ampicillin resistance and heat-stable enterotoxin activity were shown by EcoRI restriction endonuclease and genetic analysis to be in an 80-megadalton plasmid. ...

journal_title：Infection and immunity

authors： Stieglitz H,Fonseca R,Olarte J,Kupersztoch-Portnoy YM

更新日期：1980-11-01 00:00:00

abstract：:The mouse system provides an excellent model for studying host resistance to Naegleria fowleri, the agent of primary amoebic meningoencephalitis. Innate resistance to infection with N. fowleri was examined with respect to infecting dose and the age, sex, and strain of mice. Intravenous inoculation with 10(7) amoebae p...

journal_title：Infection and immunity

authors： Haggerty RM,John DT

更新日期：1978-04-01 00:00:00

abstract：:An escape variant of Borrelia burgdorferi, selected with a monoclonal antibody to OspB, expressed a truncated form of OspB, the result of point mutations in the ospB gene leading to a premature termination codon. A single amino acid position in the C terminus of OspB was critical for monoclonal antibody recognition. T...

journal_title：Infection and immunity

authors： Coleman JL,Rogers RC,Rosa PA,Benach JL

更新日期：1994-01-01 00:00:00

abstract：:Some clinical strains of Vibrio cholerae non-O1 produce an extracellular factor that evokes a rapid and dramatic cytotoxic response which manifests as cell rounding of Chinese hamster ovary (CHO) and HeLa cells without accompanying membrane damage. This study was performed to establish the identity of the non-membrane...

journal_title：Infection and immunity

authors： Saha PK,Koley H,Nair GB

更新日期：1996-08-01 00:00:00

abstract：:The importance of bacterial phospholipases during serum-mediated killing of Escherichia coli was examined by using wild-type DR+ DS+ and an isogenic phospholipase-deficient mutant DR- DS-. No difference in serum sensitivity was observed when the parental DR+ DS+ and mutant DR- DS- strains were exposed to various conce...

journal_title：Infection and immunity

authors： Kreutzer DL,Vandermaten M,Buller CS,Robertson DC,Hirata AA

更新日期：1977-10-01 00:00:00

abstract：:Mutation of retS (rtsM) of Pseudomonas aeruginosa strain PA103 reduces its virulence in both ocular and respiratory murine models of infection. In vitro, retS mutants exhibit loss of the ExsA-regulated type III secretion system (TTSS), reduced twitching motility, and a decrease in association with, invasion of, and su...

journal_title：Infection and immunity

authors： Zolfaghar I,Evans DJ,Ronaghi R,Fleiszig SM

更新日期：2006-07-01 00:00:00

abstract：:Ocular exposure of mice to live elementary bodies of Chlamydia trachomatis serovar A results in immunological sensitization of the mice. This reactivity is manifested by the development of early (5 h) and delayed-type (24 h) dermal reactivity and serovar-specific antibody formation against either live or irradiated (1...

journal_title：Infection and immunity

authors： Colley DG,Goodman TG,Barsoum IS

更新日期：1986-10-01 00:00:00

abstract：:We constructed hha derivatives from both a clinical uropathogenic Escherichia coli isolate (strain FVL4) and a wild E. coli strain causing bovine diarrhea (strain CCB21) and analyzed the effect of the hha allele on the expression of the different virulence factors exhibited by these strains. Expression of hemolysin an...

journal_title：Infection and immunity

authors： Mouriño M,Madrid C,Balsalobre C,Prenafeta A,Muñoa F,Blanco J,Blanco M,Blanco JE,Juarez A

更新日期：1996-07-01 00:00:00

abstract：:Experiments were conducted in which rhesus monkeys were infected with mumps virus by inoculation into the parotid gland. Virus was isolated from buccal swab specimens from animals up to 6 days after inoculation. Immunofluorescence staining for mumps antigen was positive, and infectious virus was recovered from tissue ...

journal_title：Infection and immunity

authors： Flanagan TD,Andrada JA,Barron AL,Witebsky E

更新日期：1971-05-01 00:00:00

abstract：:Several viruses were categorized on the basis of their ability to spread from cell to contiguous cell and form plaques in the presence of antiviral antibody. Herpes simplex virus, cytomegalovirus, and vaccinia, measles, and foamy viruses were able to spread in the presence of neutralizing antibody, whereas coxsackievi...

journal_title：Infection and immunity

authors： Hooks JJ,Burns W,Hayashi K,Geis S,Notkins AL

更新日期：1976-11-01 00:00:00

abstract：:A clone bank of Pasteurella haemolytica A1 was constructed by partial digestion of the genomic DNA with Sau3A and ligation of 5- to 10-kilobase-pair fragments into the BamHI site of the plasmid vector pBR322. After transformation into Escherichia coli K-12, a total of 4 X 10(3) recombinant clones was obtained. These w...

journal_title：Infection and immunity

authors： Lo RY,Shewen PE,Strathdee CA,Greer CN

更新日期：1985-12-01 00:00:00

abstract：:The in vitro effects of pneumolysin, a sulfhydryl-activated toxin produced by Streptococcus pneumoniae, on various functions of human polymorphonuclear leukocytes (PMNLs) was investigated. Treatment of PMNLs with highly purified toxin significantly inhibited respiratory burst (in response to stimulation), ability to k...

journal_title：Infection and immunity

authors： Paton JC,Ferrante A

更新日期：1983-09-01 00:00:00

abstract：:Phorbol myristate acetate stimulated oxidative metabolism in alveolar macrophages and blood neutrophils. This compound also stimulated lysozyme release from neutrophils but not from alveolar macrophages. These findings suggest that the regulation of lysozyme release from alveolar macrophages is different than for poly...

journal_title：Infection and immunity

authors： Biggar WD

更新日期：1978-08-01 00:00:00

abstract：:Hypoferremia, the reduction of plasma transferrin iron levels during infection, has been shown to control Neisseria meningitidis infection in mice. The exact nature of the mechanism that regulates this response has been obscure. We have previously shown that hypoferremia does not result from an accelerated removal of ...

journal_title：Infection and immunity

authors： Letendre ED,Holbein BE

更新日期：1984-05-01 00:00:00