Research: advances in cell biology relevant to critical illness.

abstract：:Nosocomial pneumonia is a dynamic disease with multiple etiologic agents and a changing natural history. The highest attack rates and mortality occur in patients with ventilator-associated pneumonia. Diagnosis of nosocomial pneumonia is often made by clinical criteria that are sensitive but lack specificity. The use o...

journal_title：Current opinion in critical care

authors： Craven DE,De Rosa FG,Thornton D

更新日期：2002-10-01 00:00:00

abstract：:Critical illness polyneuropathy (CIP) is a syndrome that was first extensively described in the early 1980s, mainly in patients with failure to wean from mechanical ventilation. The syndrome is further characterized by limb muscle weakness, usually more pronounced distally than proximally, and is often accompanied by ...

journal_title：Current opinion in critical care

authors： van Mook WN,Hulsewé-Evers RP

更新日期：2002-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Acute coagulopathy of trauma has only been described relatively recently. Developing early in the postinjury phase, it is associated with increased transfusion requirements and poor outcomes. This review examines the possible initiators, mechanism and clinical importance of acute coagulopathy. RECENT...

journal_title：Current opinion in critical care

authors： Brohi K,Cohen MJ,Davenport RA

更新日期：2007-12-01 00:00:00

abstract：PURPOSE OF REVIEW:The pulmonary artery catheter is one of the most scrutinized monitors used in intensive care today. Pulmonary artery catheter use is declining due to limited demonstrated beneficial outcomes and the advancement of less invasive monitoring. This study discusses the current use of the pulmonary artery c...

journal_title：Current opinion in critical care

authors： Greenberg SB,Murphy GS,Vender JS

更新日期：2009-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Management of the patient with traumatic brain injury is a rapidly advancing field, characterized in recent years by an improved understanding of intracranial pathophysiology and ways in which outcomes can be improved. Many traditional therapies, such as fluid restriction and hyperventilation, have be...

journal_title：Current opinion in critical care

authors： Dutton RP,McCunn M

更新日期：2003-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the clear rationale for evidence-based medicine (EvBM) in the challenging realms of resuscitation research, yet also provide case examples in which even the well designed, multicentered randomized clinical trial may have had unrecognized limitations, and thus misleading results. This is whe...

journal_title：Current opinion in critical care

authors： Pepe PE,Aufderheide TP

更新日期：2017-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a minimally invasive damage control procedure for life-threatening abdominal or pelvic haemorrhage. The purpose of this review is to summarize the current understanding and experience with REBOA, outline potential future applications...

journal_title：Current opinion in critical care

authors： Perkins ZB,Lendrum RA,Brohi K

更新日期：2016-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Therapeutic hypothermia following out-of-hospital cardiac arrest improves neurological recovery. Coupled with neurological benefit, multiple complications including infection have been associated with therapeutic hypothermia following out-of-hospital cardiac arrest. In this review, we will discuss the...

journal_title：Current opinion in critical care

authors： Kuchena A,Merkel MJ,Hutchens MP

更新日期：2014-10-01 00:00:00

abstract：:Cardiac arrest survival rates remain low despite increased access to advanced cardiac life support. Survival from cardiac arrest is, at least in part, related to the perfusion pressures and blood flow achieved during cardiopulmonary resuscitation (CPR). A number of alternative CPR devices have been developed that aim ...

journal_title：Current opinion in critical care

authors： Smith T

更新日期：2002-06-01 00:00:00

abstract：PURPOSE OF REVIEW:This article reviews current concepts in perioperative pulmonary management. RECENT FINDINGS:Preoperative risk assessment tools for perioperative pulmonary complications (POPCs) are evolving for both children and adults. Intraoperative management strategies have a demonstrable effect on outcomes. Lat...

journal_title：Current opinion in critical care

authors： Johnson DC,Kaplan LJ

更新日期：2011-08-01 00:00:00

abstract：PURPOSE OF REVIEW:The gut has long been hypothesized to be the 'motor' of multiple organ dysfunction syndrome. This review serves as an update on new data elucidating the role of the gut as the propagator of organ failure in critical illness. RECENT FINDINGS:Under basal conditions, the gut absorbs nutrients and serves...

journal_title：Current opinion in critical care

authors： Meng M,Klingensmith NJ,Coopersmith CM

更新日期：2017-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Progress has been made in our understanding of gut dysfunction in critical illness. This review will outline new findings and give perspectives based on previous knowledge and concurrent advances in nutrition. RECENT FINDINGS:The relationship between gut dysfunction and poor outcomes in critical illn...

journal_title：Current opinion in critical care

authors： Chapple LS,Plummer MP,Chapman MJ

更新日期：2021-01-21 00:00:00

abstract：PURPOSE OF REVIEW:Prerenal failure is used to designate a reversible form of acute renal dysfunction. However, the terminology encompasses several different conditions that vary considerably. The lack of a widely accepted definition for prerenal failure makes it impossible to determine the epidemiology, natural history...

journal_title：Current opinion in critical care

authors： Macedo E,Mehta RL

更新日期：2009-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Delayed awakening after targeted temperature management (TTM) and sedation is frequent among cardiac arrest patients. Differentiating between prolonged coma and irreversible cerebral damage can be challenging, therefore the utilization of a multimodal approach is recommended by international guideline...

journal_title：Current opinion in critical care

authors： Oddo M,Friberg H

更新日期：2017-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Although providing palliative care in the ICU has become a priority, the success of different methods to integrate palliative care into the ICU has varied. This review examines the current evidence supporting the different models of palliative care delivery and highlights areas for future study. RECE...

journal_title：Current opinion in critical care

authors： Hua M,Wunsch H

更新日期：2014-12-01 00:00:00

abstract：PURPOSE OF REVIEW:In the past 12 years, atherosclerosis and the acute coronary syndromes have turned out to be thromboinflammatory diseases. Recent data suggest that inflammation also plays an important role in the pathogenesis and outcome of cardiogenic shock. This review will summarize recent advances in the understa...

journal_title：Current opinion in critical care

authors： Geppert A,Huber K

更新日期：2004-10-01 00:00:00

abstract：PURPOSE OF REVIEW:Successful treatment of cardiac arrest requires that an electrically stable and mechanically competent cardiac activity be promptly reestablished. However, many interventions used to attempt to reestablish cardiac activity may also inflict additional myocardial injury and, in turn, compromise resuscit...

journal_title：Current opinion in critical care

authors： Gazmuri RJ,Ayoub IM,Kolarova J

更新日期：2003-06-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize clinical evidence for intraoperative ventilation settings, which could protect against postoperative pulmonary complications (PPCs) in surgical patients with uninjured lungs. RECENT FINDINGS:There is convincing evidence for protection against PPCs by low tidal volumes: benefit was found ...

journal_title：Current opinion in critical care

authors： Schultz MJ,Abreu MG,Pelosi P

更新日期：2015-08-01 00:00:00

abstract：PURPOSE OF REVIEW:Transfusion of red blood cells in the trauma patient can be lifesaving. The question is how much and when? It is important to weigh the risks and benefits of red blood cell transfusions, as well alternatives to transfusion as these products are not benign. RECENT FINDINGS:We explore the evidence, and...

journal_title：Current opinion in critical care

authors： McIntyre LA,Hebert PC

更新日期：2006-12-01 00:00:00

abstract：PURPOSE OF REVIEW:To discuss the role of microcirculatory abnormalities in critically ill patients and the link between systemic hemodynamics and microvascular perfusion. RECENT FINDINGS:Microcirculatory alterations have been repeatedly observed in patients with severe sepsis, but recent findings show that these also ...

journal_title：Current opinion in critical care

authors： De Backer D,Ortiz JA,Salgado D

更新日期：2010-06-01 00:00:00

abstract：PURPOSE OF REVIEW:Professional organizations, consensus groups, and stakeholders are calling for better palliative care in acute care settings, particularly in ICUs. Our ability to deliver that care is dependent on the outcomes associated with palliative care in the ICU. This review provides a conceptual framework for ...

journal_title：Current opinion in critical care

authors： Aslakson RA,Bridges JF

更新日期：2013-10-01 00:00:00

abstract：PURPOSE OF REVIEW:To summarize new concepts regarding the occurrence, prevention, and management of medical complications following subarachnoid hemorrhage. RECENT FINDINGS:Data regarding the impact of common medical complications after subarachnoid hemorrhage on delayed cerebral ischemia and neurological outcome afte...

journal_title：Current opinion in critical care

authors： Wartenberg KE,Mayer SA

更新日期：2006-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Mechanical ventilation is a common intervention provided by pediatric intensivists. This fact notwithstanding, the management of mechanical ventilation in pediatrics is largely guided by a few pediatric trials along with careful interpretation and application of adult data. RECENT FINDINGS:A low tida...

journal_title：Current opinion in critical care

authors： Turner DA,Arnold JH

更新日期：2007-02-01 00:00:00

abstract：:The use of therapeutic moderate hypothermia for treating severe traumatic brain injury has been reported for more than 50 years. However, the most intense investigation of this treatment has occurred during the last 10 to 15 years. Virtually all preclinical studies have documented a robust treatment effect, not only i...

journal_title：Current opinion in critical care

authors： Marion DW

更新日期：2002-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Acute respiratory distress syndrome has been considered a morphologic and functional expression of lung injury caused by a variety of insults. Two distinct forms of acute respiratory distress syndrome/acute lung injury are described, because there are differences between pulmonary acute respiratory di...

journal_title：Current opinion in critical care

authors： Rocco PR,Zin WA

更新日期：2005-02-01 00:00:00

abstract：PURPOSE OF REVIEW:Multiple factors influence the dependability of intensive care provision. The management of a group of unstable, critically ill patients requires focused attention from the clinical team. Medical simulation is an important tool to improve safety and team work within the ICU. RECENT FINDINGS:The criti...

journal_title：Current opinion in critical care

authors： Fox-Robichaud AE,Nimmo GR

更新日期：2007-12-01 00:00:00

abstract：PURPOSE OF REVIEW:Ventilator weaning forms an integral part in critical care medicine and strategies to shorten duration are rapidly evolving alongside our knowledge of the relevant physiological processes. The purpose of the current review is to discuss new physiological and clinical insights in ventilator weaning tha...

journal_title：Current opinion in critical care

authors： Haaksma ME,Tuinman PR,Heunks L

更新日期：2021-02-01 00:00:00

abstract：:Tracheostomy is one of the most common surgical procedures in the intensive care unit. Since the introduction of percutaneous techniques, tracheostomy has become increasingly popular. The technique is relatively easy, and the early and late complication rates are relatively low.It is unknown at which moment tracheosto...

journal_title：Current opinion in critical care

authors： van Heurn LW

更新日期：2000-08-01 00:00:00

abstract：PURPOSE OF REVIEW:To review and examine the efficacy of recently described medical and surgical interventions after acute ischaemic stroke using data from well conducted, clinical trials and systematic reviews. This review will consider recently published or updated articles. RECENT FINDINGS:As therapeutic options evo...

journal_title：Current opinion in critical care

authors： Andrews PJ

更新日期：2004-04-01 00:00:00

abstract：PURPOSE OF REVIEW:Research and studies related to the long-term consequences of intensive care are increasing. This review focuses on some of the most recent knowledge in this field. RECENT FINDINGS:Still studies regarding the health-related quality of life (HRQOL) in survivors after intensive care are frequently publ...

journal_title：Current opinion in critical care

authors： Flaatten H

更新日期：2010-10-01 00:00:00