Abstract：
PURPOSE:This study explored the role of the left posterior parietal cortex (PPC) in saccades, vergence, and combined saccade-vergence movements by means of transcranial magnetic stimulation (TMS) in humans. METHODS:TMS was applied over the left PPC for 80, 90, or 100 ms after target onset. In a control experiment, TMS was applied over the primary motor cortex at 90 ms after target onset. RESULTS:Relative to no TMS trials, TMS over the left PPC increased the latency of only certain types of eye movements: saccades to right, convergence, and convergence combined with rightward saccades. It had no such effect on saccades to the left, divergence, saccades combined with divergence, or left saccades combined with convergence. TMS over the vertex had no effect on the latency of any type of eye movement. Thus, the effects of TMS on latency are both area- and eye-movement specific. TMS of the left PPC or the motor cortex did not alter the accuracy of any type of eye movement. The results are in contrast to those of prior studies of the right PPC, which is involved in the initiation of any type of eye movement. CONCLUSIONS:The findings suggest that the right PPC is involved primarily in the processing of fixation disengagement, whereas the left PPC provides the signal that is also necessary to initiate eye movements and could occur in parallel with the process (model of Findlay and Walker). Such a functional role of the left PPC seems to be topographically organized and concerns a saccade to the right and convergence alone or combined with a saccade to the right.
journal_name
Invest Ophthalmol Vis Scijournal_title
Investigative ophthalmology & visual scienceauthors
Yang Q,Kapoula Zdoi
10.1167/iovs.03-1291keywords:
subject
Has Abstractpub_date
2004-07-01 00:00:00pages
2231-9issue
7eissn
0146-0404issn
1552-5783journal_volume
45pub_type
杂志文章abstract：PURPOSE:This study sought to examine the acute effects of ocular ischemia and reperfusion on retinal function and determine the extent to which recovery during reperfusion is improved by allopurinol (AP), a blocker of xanthine oxidase (XO). The latter is presumed to be a major factor in the formation of free radicals a...
journal_title：Investigative ophthalmology & visual science
pub_type： 杂志文章
doi：
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abstract：PURPOSE:To examine the relationship between circulating inflammatory markers, hemostatic factors, and age-related maculopathy (ARM). METHODS:A population-based, cross-sectional case-control study drawn from the Blue Mountains Eye Study included 159 early and 38 late ARM cases, and 433 controls matched for age, gender,...
journal_title：Investigative ophthalmology & visual science
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journal_title：Investigative ophthalmology & visual science
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journal_title：Investigative ophthalmology & visual science
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更新日期：2009-02-01 00:00:00
abstract：PURPOSE:To describe the variation in ocular biometry in adult Chinese individuals in Singapore. METHODS:This study was a population-based, cross-sectional survey of adult Chinese persons aged 40 to 81 years residing in Tanjong Pagar district, Singapore. Axial ocular dimensions, including axial length (AL), anterior ch...
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journal_title：Investigative ophthalmology & visual science
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doi：
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doi：
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journal_title：Investigative ophthalmology & visual science
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journal_title：Investigative ophthalmology & visual science
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doi：
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journal_title：Investigative ophthalmology & visual science
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doi：
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